Neurosurgery Thesis Topics

NEUROSURGERY THESIS TOPICS FOR Mch/DNB

Neurosurgery thesis topics

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Neurosurgery Thesis Topics

SECTION 1: TRAUMATIC BRAIN INJURY AND NEUROTRAUMA
  1. Comparative study on outcomes of early versus delayed decompressive craniectomy in severe traumatic brain injury in Indian tertiary hospitals.

  2. Randomised controlled trial evaluating the role of hypothermia therapy in improving neurological outcomes in patients with severe head injury.

  3. Observational study on the correlation between Marshall CT classification and long-term functional outcomes in moderate to severe head injury.

  4. Comparative analysis of hypertonic saline versus mannitol in the control of raised intracranial pressure in traumatic brain injury patients.

  5. Retrospective study assessing predictors of mortality in patients undergoing surgery for acute subdural hematoma.

  6. Randomised controlled trial comparing early tracheostomy versus late tracheostomy in traumatic brain injury patients requiring prolonged ventilation.

  7. Prospective study evaluating the utility of serum neuron-specific enolase in prognostication after traumatic brain injury.

  8. Comparative study of conservative versus surgical management of traumatic brain contusions with midline shift less than 5 mm.

  9. Retrospective analysis of post-traumatic hydrocephalus incidence following decompressive craniectomy in traumatic brain injury.

  10. Prospective cohort study on the role of continuous electroencephalogram monitoring in detecting subclinical seizures in severe traumatic brain injury.

SECTION 2: SPINAL DISORDERS AND SPINAL SURGERY

  1. Randomised controlled trial comparing minimally invasive versus open lumbar discectomy in patients with single-level lumbar disc herniation.

  2. Comparative study of clinical outcomes between posterior cervical fusion and anterior cervical discectomy and fusion in multi-level cervical spondylotic myelopathy.

  3. Observational study evaluating the incidence and management outcomes of spinal tuberculosis in a high-burden Indian centre.

  4. Retrospective study comparing outcomes of laminectomy versus laminoplasty in cervical compressive myelopathy.

  5. Comparative analysis of long-term outcomes in lumbar canal stenosis treated with decompression alone versus decompression with fusion.

  6. Randomised controlled trial assessing the effectiveness of epidural steroid injection versus surgical decompression in lumbar radiculopathy.

  7. Prospective study on outcomes of instrumentation versus non-instrumented fusion in thoracolumbar spinal trauma.

  8. Comparative study of surgical outcomes in anterior versus posterior approaches in cervical spine tuberculosis.

  9. Retrospective study assessing the rate of surgical site infections in spine surgeries using conventional versus antibiotic-coated implants.

  10. Observational study of functional recovery in patients undergoing surgery for intramedullary spinal cord tumors.

SECTION 3: VASCULAR NEUROSURGERY

  1. Comparative study of endovascular coiling versus microsurgical clipping in patients with ruptured anterior communicating artery aneurysms.

  2. Randomised controlled trial comparing intraoperative indocyanine green video angiography versus digital subtraction angiography in aneurysm clipping surgeries.

  3. Retrospective study assessing predictors of outcome in patients with spontaneous intracerebral hemorrhage undergoing surgical evacuation.

  4. Prospective study evaluating the use of flow diverters in the management of large and giant intracranial aneurysms.

  5. Comparative analysis of surgical versus endovascular treatment in patients with brain arteriovenous malformations.

  6. Randomised controlled trial evaluating outcomes of early surgery versus conservative management in cerebellar hemorrhage with mass effect.

  7. Observational study of perioperative complications in cerebral revascularization surgeries in Indian patients with moyamoya disease.

  8. Retrospective analysis of outcomes of patients undergoing decompressive hemicraniectomy for malignant middle cerebral artery infarction.

  9. Prospective study comparing surgical outcome in patients with ruptured versus unruptured posterior circulation aneurysms.

  10. Comparative evaluation of hybrid operating room versus conventional setup in surgical management of complex vascular lesions.

SECTION 4: NEURO-ONCOLOGY

  1. Randomised controlled trial comparing awake craniotomy versus general anesthesia in eloquent area glioma surgeries.

  2. Comparative study of extent of resection and neurological outcomes in low-grade gliomas using intraoperative magnetic resonance imaging versus conventional surgery.

  3. Observational study on survival and recurrence rates in patients with glioblastoma treated with surgery followed by temozolomide and radiotherapy.

  4. Retrospective study evaluating prognostic factors in patients undergoing resection for brain metastases from lung carcinoma.

  5. Prospective study of cognitive function and quality of life in patients undergoing surgery for low-grade gliomas.

  6. Comparative study of surgical outcomes between meningiomas located at convexity and skull base.

  7. Randomised controlled trial evaluating early versus delayed surgery in patients with incidental low-grade glioma.

  8. Observational study on the pattern of recurrence in high-grade gliomas in relation to extent of resection and adjuvant therapy.

  9. Retrospective analysis of complications in patients undergoing resection of giant vestibular schwannomas.

  10. Comparative evaluation of functional outcome in patients with spinal cord tumors managed with gross total versus subtotal resection.

SECTION 5: FUNCTIONAL NEUROSURGERY AND EPILEPSY SURGERY

  1. Randomised controlled trial comparing deep brain stimulation versus lesioning in medically refractory Parkinson’s disease.

  2. Comparative study of anterior temporal lobectomy versus selective amygdalohippocampectomy in patients with drug-resistant temporal lobe epilepsy.

  3. Observational study on neuropsychological outcome in patients undergoing epilepsy surgery for mesial temporal sclerosis.

  4. Retrospective analysis of seizure freedom and quality of life after surgery for focal cortical dysplasia.

  5. Prospective study comparing vagus nerve stimulation and medical management in refractory epilepsy.

  6. Randomised controlled trial evaluating subthalamic versus globus pallidus stimulation in advanced Parkinson’s disease.

  7. Comparative study of outcomes of surgical management versus medical therapy in patients with hemifacial spasm.

  8. Observational study of outcomes and complications in patients undergoing dorsal rhizotomy for spasticity.

  9. Retrospective analysis of long-term seizure outcomes in pediatric epilepsy surgery.

  10. Comparative evaluation of intraoperative electrocorticography versus preoperative imaging in identifying seizure foci.

SECTION 6: CONGENITAL NEUROSURGICAL DISORDERS

  1. Comparative study of outcomes in children with myelomeningocele undergoing early versus delayed repair.

  2. Randomised controlled trial comparing ventriculoperitoneal shunting versus endoscopic third ventriculostomy in infants with congenital hydrocephalus.

  3. Observational study on neurodevelopmental outcomes in children with Dandy-Walker malformation undergoing surgical intervention.

  4. Retrospective analysis of surgical outcomes in patients with Chiari I malformation with and without syringomyelia.

  5. Comparative study of posterior fossa decompression with versus without duraplasty in pediatric Chiari malformation.

  6. Randomised controlled trial evaluating the efficacy of endoscopic versus open surgical treatment of arachnoid cysts in pediatric patients.

  7. Observational study of surgical complications and long-term outcome in children undergoing detethering of spinal cord.

  8. Retrospective study on the incidence of shunt malfunction in pediatric hydrocephalus managed with programmable versus fixed pressure valves.

  9. Prospective study comparing neurodevelopmental outcomes in children with craniosynostosis treated surgically versus conservatively.

  10. Comparative evaluation of open versus endoscopic cranial vault remodeling in children with sagittal craniosynostosis.

SECTION 7: PERIPHERAL NERVE SURGERY

  1. Comparative study of surgical outcomes in patients undergoing nerve transfer versus nerve grafting in brachial plexus injuries.

  2. Randomised controlled trial evaluating functional recovery following sural nerve grafting in traumatic sciatic nerve injury.

  3. Observational study on clinical and electrophysiological outcomes following decompression surgery in carpal tunnel syndrome.

  4. Retrospective analysis of surgical outcomes in patients undergoing ulnar nerve transposition for cubital tunnel syndrome.

  5. Comparative study of early versus delayed repair of facial nerve injuries due to trauma.

  6. Randomised controlled trial evaluating platelet-rich plasma versus saline injection in improving nerve regeneration post-repair.

  7. Prospective study assessing outcomes of surgical management in traumatic peroneal nerve injuries.

  8. Comparative study of tendon transfer versus nerve grafting in neglected radial nerve palsy.

  9. Retrospective study on surgical outcomes in schwannomas of peripheral nerves in extremities.

  10. Observational study on quality of life in patients with chronic pain following peripheral nerve injuries.

SECTION 8: HYDROCEPHALUS AND CEREBROSPINAL FLUID DISORDERS

  1. Comparative study of complications between ventriculoperitoneal and ventriculoatrial shunt placements in hydrocephalus.

  2. Randomised controlled trial comparing programmable versus fixed pressure valves in patients undergoing cerebrospinal fluid shunting.

  3. Observational study on the utility of endoscopic third ventriculostomy in post-tuberculous hydrocephalus.

  4. Retrospective analysis of cerebrospinal fluid overdrainage syndrome in patients with shunts for normal pressure hydrocephalus.

  5. Comparative evaluation of endoscopic third ventriculostomy outcomes in aqueductal stenosis versus post-hemorrhagic hydrocephalus.

  6. Prospective study of infection rates in external ventricular drainage versus lumbar drainage in patients with cerebrospinal fluid leaks.

  7. Randomised controlled trial assessing the efficacy of prophylactic antibiotics in reducing shunt infections.

  8. Comparative study of outcomes in patients with cerebrospinal fluid rhinorrhea treated with endoscopic versus open surgical repair.

  9. Retrospective study on long-term outcomes of shunt surgeries in congenital hydrocephalus.

  10. Observational study on complications and outcomes in patients undergoing revision of ventriculoperitoneal shunt.

SECTION 9: SKULL BASE SURGERY

  1. Comparative study of endoscopic endonasal versus transcranial approach in anterior skull base meningiomas.

  2. Randomised controlled trial evaluating intraoperative neuromonitoring in skull base tumor resections involving cranial nerves.

  3. Observational study on postoperative cerebrospinal fluid leaks following endoscopic skull base surgeries.

  4. Retrospective study of clinical outcomes and complications in patients undergoing resection of clival chordomas.

  5. Comparative analysis of gross total versus subtotal resection in patients with petroclival meningiomas.

  6. Prospective study on visual outcomes following surgery for tuberculum sellae meningiomas.

  7. Randomised controlled trial comparing nasal mucosal flap versus fascia lata graft for skull base defect reconstruction.

  8. Observational study on management strategies for recurrent skull base tumors.

  9. Retrospective study evaluating surgical outcomes in glomus jugulare tumors operated via infratemporal fossa approach.

  10. Comparative study of operative duration, blood loss, and outcomes between open and endoscopic skull base surgeries.

SECTION 10: NEUROCRITICAL CARE AND POSTOPERATIVE MANAGEMENT

 

  1. Randomised controlled trial comparing early versus late mobilization in neurosurgical intensive care patients.

  2. Comparative study of different weaning strategies from mechanical ventilation in postoperative neurosurgical patients.

  3. Observational study on incidence and predictors of deep vein thrombosis in neurosurgical intensive care patients.

  4. Retrospective analysis of electrolyte disturbances and their impact on outcomes in neurocritical care.

  5. Prospective study evaluating outcomes of early enteral nutrition in postoperative neurosurgical patients.

  6. Randomised controlled trial comparing intensive blood pressure control versus standard care in aneurysmal subarachnoid hemorrhage.

  7. Comparative study on infection rates in patients with external ventricular drain versus lumbar drain.

  8. Observational study on the utility of neuromonitoring parameters in predicting neurological recovery in comatose patients post-neurosurgery.

  9. Retrospective analysis of causes and outcomes of unplanned re-operations in neurosurgical cases.

  10. Comparative study evaluating outcomes in patients managed with standard intensive care versus neurosurgical high-dependency unit following elective craniotomy.

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