Transfusion Medicine THESIS TOPICS FOR MD/DNB

Research Topics

Transfusion Medicine Thesis Topics

Choosing the right transfusion medicine thesis topics is critical for ensuring a strong academic foundation and career progression in medical research. Carefully selected transfusion medicine thesis topics allow students to focus on cutting-edge areas such as blood component therapy, transfusion-transmitted infections, immunohematology, transfusion practices in critical care, and hemovigilance.

These sections provide ample scope for research innovation. Moreover, well-structured transfusion medicine thesis topics pave the way for high-quality dissertations that can be published in reputed medical journals—a key requirement for academic promotions and faculty appointments.

A meticulously chosen transfusion medicine thesis topic not only reflects scholarly intent but also contributes significantly to advancements in patient care and clinical guidelines. Therefore, invest time and effort in selecting the most relevant transfusion medicine thesis topics aligned with both your interest and research trends.

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📌 Updated for 2025–2026 MD Transfusion Medicine Thesis Topics
This Transfusion Medicine thesis topics list is updated for the 2025–2026 academic cycle. These topics are curated based on recent dissertations, examiner expectations, feasibility in Indian blood banks and transfusion services, and publication trends in hematology and transfusion journals.

High-yield and clinically important transfusion research areas
Feasible studies using routine blood bank, component lab and transfusion service workload
Thesis topics with strong publication potential in transfusion science journals

A hospital-based observational study evaluating the reasons for donor deferral and its impact on donor return rates in a tertiary care blood bank.
A comparative study analyzing the impact of pre-donation hydration strategies on vasovagal reactions in voluntary blood donors.
A prospective study evaluating the effect of donor education and counseling on donor retention and repeat donation rates.
A randomized controlled trial comparing the impact of different hemoglobin screening methods on donor acceptance and deferral rates in blood donation camps.
A hospital-based comparative study assessing the prevalence of iron deficiency in regular blood donors versus first-time blood donors.
A prospective observational study evaluating the effect of frequent blood donation on ferritin levels and hemoglobin recovery in voluntary blood donors.
A retrospective study analyzing the trends in voluntary versus replacement blood donation and its impact on blood component availability.
A prospective study evaluating the effectiveness of mobile blood donation drives in increasing donor participation in rural areas.
A hospital-based study assessing the impact of incentives on voluntary blood donor motivation and donation frequency.
A comparative study on the prevalence of infectious markers in voluntary versus replacement blood donors in a tertiary care center.
A prospective study evaluating the effect of different anticoagulants on storage lesion development in packed red blood cells.
A hospital-based comparative study analyzing the impact of different storage temperatures on platelet function and viability.
A randomized controlled trial evaluating the efficacy of rejuvenation solutions in extending the shelf life of stored red blood cells.
A prospective study assessing the impact of leukoreduction on the incidence of febrile non-hemolytic transfusion reactions in thalassemia patients.
A hospital-based study analyzing the changes in metabolic parameters in stored packed red blood cells over different storage durations.
A retrospective study comparing the clinical outcomes of patients receiving fresh versus stored red blood cell transfusions in intensive care units.
A prospective observational study evaluating the impact of irradiation on post-transfusion complications in immunocompromised patients.
A randomized controlled trial assessing the impact of washing red blood cells on transfusion-related adverse reactions in neonates.
A comparative study evaluating the efficacy of different platelet additive solutions in improving platelet storage quality.
A prospective study analyzing the impact of red cell deformability on post-transfusion oxygen delivery in critically ill patients.
A hospital-based study assessing the prevalence of weak D variants and its impact on RhD typing in blood donors and recipients.
A retrospective study analyzing the incidence and clinical significance of Rh and Kell alloimmunization in multi-transfused patients.
A comparative study evaluating the performance of different gel card techniques in detecting irregular antibodies in pregnant women.
A hospital-based observational study assessing the prevalence of naturally occurring anti-M antibodies and its impact on transfusion compatibility.
A prospective study evaluating the role of molecular genotyping in resolving blood group discrepancies in patients requiring chronic transfusions.
A hospital-based study analyzing the incidence of ABO-incompatible platelet transfusion and its impact on transfusion outcomes.
A comparative study evaluating the clinical significance of anti-E and anti-c alloantibodies in multi-transfused sickle cell disease patients.
A prospective study assessing the impact of donor-recipient HLA matching on platelet transfusion efficacy in alloimmunized patients.
A retrospective study analyzing the prevalence and impact of RhD alloimmunization in pregnant women and hemolytic disease of the fetus and newborn.
A hospital-based study evaluating the use of extended red cell antigen matching in reducing alloimmunization in thalassemia patients.
A randomized controlled trial comparing the effectiveness of pathogen-reduced versus standard platelets in reducing transfusion-related infections.
A prospective study evaluating the impact of apheresis platelet transfusion versus random donor platelets on platelet recovery in thrombocytopenic patients.
A hospital-based comparative study assessing the efficacy of cryopreserved platelets versus fresh platelets in trauma-induced coagulopathy.
A retrospective study analyzing the trends in platelet utilization and wastage in a tertiary care hospital.
A prospective study evaluating the impact of ABO compatibility on the efficacy of platelet transfusion in oncology patients.
A hospital-based observational study assessing the incidence of platelet refractoriness and its correlation with HLA alloimmunization.
A randomized controlled trial comparing the clinical outcomes of prophylactic versus therapeutic platelet transfusion in dengue-associated thrombocytopenia.
A retrospective study analyzing the role of mean platelet volume in predicting platelet transfusion requirements in critically ill patients.
A prospective observational study evaluating the impact of pathogen-reduced platelets on post-transfusion bleeding risk in hematology patients.
A hospital-based study assessing the role of platelet microparticles in transfusion efficacy and thrombotic complications in critically ill patients.
A comparative study evaluating the impact of different massive transfusion protocols on outcomes in trauma patients with hemorrhagic shock.
A hospital-based retrospective study analyzing the incidence and predictors of coagulopathy in trauma patients requiring massive transfusion.
A randomized controlled trial comparing fibrinogen concentrate versus cryoprecipitate in the management of trauma-induced coagulopathy.
A prospective observational study evaluating the impact of point-of-care viscoelastic hemostatic assays on blood product utilization in massive transfusion.
A hospital-based study analyzing the role of whole blood transfusion versus component therapy in patients with severe hemorrhage.
A retrospective study evaluating the trends in plasma transfusion practices and its impact on patient outcomes in a tertiary care center.
A prospective study analyzing the effectiveness of early platelet transfusion in preventing traumatic brain injury-associated coagulopathy.
A hospital-based comparative study assessing the effectiveness of high-ratio plasma to red blood cell transfusion in reducing mortality in trauma patients.
A randomized controlled trial comparing the efficacy of prothrombin complex concentrate versus fresh frozen plasma in the reversal of anticoagulation.
A retrospective study evaluating the role of transfusion algorithms in optimizing blood product usage in patients undergoing major surgery.
A prospective study evaluating the effect of pathogen reduction on the clotting factor activity in plasma transfusions.
A hospital-based observational study analyzing the impact of transfusion-related immunomodulation on sepsis risk in critically ill patients.
A randomized controlled trial comparing the effectiveness of fresh frozen plasma versus solvent-detergent plasma in correcting coagulopathy.
A retrospective study analyzing the impact of ABO-incompatible plasma transfusion on clinical outcomes in patients undergoing liver transplantation.
A prospective observational study assessing the role of fibrinogen levels in predicting transfusion requirements in postpartum hemorrhage.
A hospital-based comparative study evaluating the safety and efficacy of solvent-detergent plasma versus cryoprecipitate in disseminated intravascular coagulation.
A randomized controlled trial comparing early plasma transfusion versus standard care in patients with sepsis-induced coagulopathy.
A retrospective study analyzing the incidence and outcomes of transfusion-associated circulatory overload in pediatric versus adult intensive care unit patients.
A prospective study evaluating the effectiveness of individualized transfusion strategies in patients with chronic liver disease and bleeding tendencies.
A hospital-based study analyzing the impact of prolonged storage on coagulation factor levels in fresh frozen plasma.
A randomized controlled trial assessing the effectiveness of pooled solvent-detergent plasma versus standard fresh frozen plasma in patients undergoing cardiac surgery.
A prospective observational study evaluating the effect of hyperhemolysis syndrome in sickle cell disease patients requiring chronic transfusions.
A hospital-based comparative study analyzing the prevalence and risk factors for alloimmunization in thalassemia major patients receiving chronic transfusions.
A retrospective study evaluating the clinical impact of red cell exchange transfusion versus simple transfusion in sickle cell crisis management.
A prospective study assessing the long-term effects of chronic transfusions on iron overload and liver function in thalassemia patients.
A hospital-based study analyzing the role of therapeutic red cell exchange in the management of stroke prevention in sickle cell disease patients.
A randomized controlled trial comparing the efficacy of iron chelation therapy in patients with transfusion-dependent anemia receiving different transfusion regimens.
A retrospective study evaluating the transfusion requirements and complications in patients with myelodysplastic syndrome receiving chronic transfusions.
A hospital-based observational study assessing the impact of extended antigen matching on transfusion efficacy and alloimmunization in sickle cell disease patients.
A prospective study analyzing the effect of donor age and sex on transfusion outcomes in multi-transfused hematology patients.
A randomized controlled trial comparing prophylactic versus therapeutic red cell exchange transfusion in acute chest syndrome in sickle cell disease.
A hospital-based comparative study assessing the impact of leukoreduction on alloimmunization and transfusion reactions in transfusion-dependent patients.
A prospective observational study analyzing the impact of transfusion thresholds on outcomes in neonates requiring red blood cell transfusions.
A retrospective study evaluating the incidence and impact of transfusion-induced iron overload in patients with aplastic anemia.
A hospital-based study analyzing the effectiveness of extended red cell antigen matching in reducing hemolytic transfusion reactions in hematology patients.
A prospective study evaluating the role of therapeutic plasma exchange in the management of thrombotic thrombocytopenic purpura.
A randomized controlled trial comparing different anticoagulants in apheresis procedures and their impact on donor adverse events.
A hospital-based study analyzing the impact of granulocyte apheresis therapy in patients with refractory neutropenia-related infections.
A retrospective study assessing the outcomes of plasma exchange in critically ill patients with Guillain-Barré syndrome.
A prospective study evaluating the role of leukapheresis in the management of patients with hyperleukocytosis due to acute leukemia.
A hospital-based comparative study analyzing the impact of red cell exchange versus simple transfusion in the management of severe malaria.
A randomized controlled trial comparing different therapeutic plasma exchange regimens in patients with severe autoimmune diseases.
A prospective study evaluating the effectiveness of therapeutic platelet apheresis in patients with thrombotic thrombocytopenic purpura.
A hospital-based observational study assessing the outcomes of extracorporeal photopheresis in patients with steroid-refractory graft-versus-host disease.
A retrospective study analyzing the impact of therapeutic plasma exchange in critically ill patients with severe hypertriglyceridemia-induced pancreatitis.
A prospective study evaluating the role of apheresis in the management of severe dengue with hyperfibrinolysis.
A hospital-based study assessing the impact of different anticoagulants on platelet yield and donor adverse effects in platelet apheresis.
A randomized controlled trial comparing plasma exchange versus intravenous immunoglobulin therapy in patients with chronic inflammatory demyelinating polyneuropathy.
A retrospective study evaluating the safety and efficacy of double-volume exchange transfusion in neonatal hyperbilirubinemia.
A hospital-based study analyzing the prevalence and clinical outcomes of transfusion-related acute lung injury in critically ill patients.
A prospective study evaluating the impact of transfusion-associated graft-versus-host disease prevention strategies in immunocompromised patients.
A hospital-based comparative study assessing the incidence and severity of hemolytic transfusion reactions in patients receiving ABO-mismatched platelet transfusions.
A randomized controlled trial evaluating the efficacy of pre-storage leukoreduction in reducing febrile non-hemolytic transfusion reactions.
A retrospective study analyzing the role of machine learning in predicting transfusion reactions based on pre-transfusion parameters.
A prospective observational study evaluating the impact of delayed transfusion reactions on hemoglobin recovery and patient outcomes.
A hospital-based study assessing the risk factors and outcomes of transfusion-associated circulatory overload in neonates and pediatric patients.
A retrospective study evaluating the incidence and clinical impact of transfusion-associated bacterial sepsis in a tertiary care blood bank.
A prospective study analyzing the impact of transfusion protocols on minimizing hemolysis in neonatal exchange transfusion.
A hospital-based study assessing the effectiveness of gamma-irradiated blood products in preventing transfusion-associated graft-versus-host disease.
A randomized controlled trial evaluating the efficacy of universal leukoreduction versus targeted leukoreduction in reducing transfusion-related complications.

Frequently Asked Questions – Transfusion Medicine Thesis Topics (2025–2026)

1. How do I choose a feasible MD Transfusion Medicine thesis topic for the 2025–2026 academic year?

Choose a topic based on routine blood bank operations such as antibody screening, component preparation, donor selection, transfusion reactions and compatibility testing. Ensure adequate sample size, reliable data availability and feasibility of performing required tests within your centre’s facilities.

2. Which study designs are commonly accepted for MD Transfusion Medicine theses?

Common designs include cross-sectional studies, retrospective record-based analyses, immunohematology profiling, donor demographic studies, transfusion reaction audits, component utilization audits, and diagnostic accuracy studies for blood grouping or antibody detection methods. These designs are practical and preferred across Indian transfusion services.

3. What should I discuss with my guide before finalising a Transfusion Medicine thesis topic?

Discuss donor availability, data completeness in blood bank software/logbooks, need for specialized immunohematology equipment, feasibility of follow-up for transfusion reactions, and workload distribution in your centre. Confirm that similar topics were recently approved in your university and that the proposed study can yield meaningful outcomes within the residency period.