Ophthalmology thesis topics for MS/DNB

1. Cornea and Ocular Surface Disorders

1. Comparative study of visual outcomes and complications between deep anterior lamellar keratoplasty and penetrating keratoplasty in patients with keratoconus.

2. A cross-sectional study on the prevalence and pattern of dry eye disease among computer professionals in urban India.

3. Observational study on the microbial profile and antibiotic susceptibility in infectious keratitis in a tertiary care hospital.

4. Comparative evaluation of therapeutic outcomes of amniotic membrane transplantation versus conventional therapy in non-healing corneal ulcers.

5. A prospective study on the correlation of tear film breakup time and Schirmer’s test in patients with autoimmune connective tissue disorders.

6. Cross-sectional study assessing quality of life in patients with pterygium before and after surgical excision.

7. Comparative study of clinical outcomes between topical cyclosporine and corticosteroids in vernal keratoconjunctivitis.

8. Observational study of meibomian gland dysfunction and its association with systemic conditions in elderly patients.

9. Evaluation of corneal nerve density using in vivo confocal microscopy in patients with type 2 diabetes mellitus.

10. Comparative study of visual acuity outcomes after collagen cross-linking with epithelium-on versus epithelium-off techniques in keratoconus.

2. Lens and Cataract

1. Comparative study of visual outcomes and patient satisfaction between multifocal and monofocal intraocular lenses in cataract surgery.

2. Cross-sectional analysis of preoperative factors influencing intraoperative complications in phacoemulsification.

3. Observational study on posterior capsular opacification rates in hydrophobic versus hydrophilic intraocular lenses over a two-year follow-up.

4. Comparative study of intraoperative and postoperative outcomes in manual small incision cataract surgery versus phacoemulsification in rural India.

5. Assessment of biometric changes in the crystalline lens with age using optical coherence biometry.

6. Cross-sectional study of barriers to early cataract surgery uptake in geriatric population of a semi-urban Indian community.

7. Comparative study of corneal endothelial cell loss in phacoemulsification versus femtosecond laser-assisted cataract surgery.

8. Prospective observational study on visual outcomes after cataract surgery in patients with pseudoexfoliation syndrome.

9. Comparative study of intraocular pressure changes post-cataract surgery with different viscoelastic agents.

10. Cross-sectional study on cataract surgical coverage and associated factors in a tribal population.

3. Glaucoma

1. Comparative study of intraocular pressure control between prostaglandin analogs and beta-blockers in primary open-angle glaucoma.

2. Observational study on correlation between central corneal thickness and intraocular pressure in patients with glaucoma.

3. Cross-sectional analysis of visual field defects and their impact on quality of life in primary open-angle glaucoma patients.

4. Comparative study of ocular hypotensive efficacy and side-effect profile of brimonidine and timolol in Indian patients.

5. Evaluation of structural changes in retinal nerve fiber layer using OCT in patients with ocular hypertension.

6. Cross-sectional study of angle configuration in primary angle closure suspects using anterior segment OCT.

7. Observational study on compliance and barriers to glaucoma medication adherence in an Indian tertiary care setting.

8. Comparative study of outcomes between trabeculectomy with mitomycin C and Ahmed glaucoma valve implantation in refractory glaucoma.

9. Cross-sectional study of glaucoma awareness among first-degree relatives of patients with primary open-angle glaucoma.

10. Prospective study of visual outcomes after minimally invasive glaucoma surgeries in Indian patients.

4. Retina and Vitreous

1. Observational study on pattern of diabetic retinopathy in patients attending a tertiary care hospital in North India.

2. Comparative study of intravitreal bevacizumab versus ranibizumab in treatment-naïve diabetic macular edema.

3. Cross-sectional study on macular thickness and visual acuity in patients with idiopathic epiretinal membrane using spectral-domain OCT.

4. Observational study on the prevalence and clinical features of retinal vein occlusion in hypertensive patients.

5. Comparative study of surgical outcomes of pars plana vitrectomy with and without internal limiting membrane peeling in macular hole repair.

6. Evaluation of choroidal thickness in patients with high myopia using swept-source OCT.

7. Cross-sectional study on retinal findings in patients with dengue fever in a tertiary care hospital.

8. Observational study of retinal detachment patterns and surgical outcomes in pseudophakic patients.

9. Prospective study on long-term visual outcomes of patients receiving anti-VEGF therapy for neovascular age-related macular degeneration.

10. Comparative study of outcomes of pneumatic retinopexy versus scleral buckle in rhegmatogenous retinal detachment.

5. Uveitis and Intraocular Inflammation

1. Observational study on clinical spectrum and etiology of uveitis in a tertiary care center in South India.

2. Cross-sectional study on systemic associations in patients with non-infectious anterior uveitis.

3. Comparative study of efficacy of oral corticosteroids versus periocular steroid injections in intermediate uveitis.

4. Evaluation of diagnostic utility of aqueous humor polymerase chain reaction in infectious uveitis.

5. Cross-sectional study on HLA-B27 positivity and its correlation with recurrent anterior uveitis.

6. Observational study on visual outcomes in pediatric uveitis cases with different treatment regimens.

7. Comparative study of posterior uveitis due to tuberculosis versus sarcoidosis using multimodal imaging.

8. Prospective study on complications and outcomes in patients with panuveitis under immunosuppressive therapy.

9. Cross-sectional study of choroidal thickness in patients with active and quiescent uveitis.

10. Comparative study of biological therapy versus conventional immunosuppressives in refractory non-infectious uveitis.

6. Pediatric Ophthalmology and Strabismus

1. Observational study on the pattern and etiology of pediatric strabismus in an Indian tertiary care center.

2. Cross-sectional analysis of refractive errors in school-going children in semi-urban India.

3. Comparative study of visual outcomes after early versus late amblyopia therapy in children aged 3–8 years.

4. Observational study on association of ocular findings in children with cerebral palsy.

5. Prospective study on surgical outcomes in patients with intermittent exotropia undergoing bilateral lateral rectus recession.

6. Cross-sectional study on prevalence of convergence insufficiency in adolescents using smartphones.

7. Comparative study of botulinum toxin injection versus surgery in essential infantile esotropia.

8. Observational study of ocular manifestations in children with Down syndrome.

9. Cross-sectional study on awareness and health-seeking behavior of parents regarding childhood eye diseases.

10. Comparative study of binocular vision outcomes in accommodative versus non-accommodative esotropia.

7. Neuro-Ophthalmology

1. Cross-sectional study on visual field defects in patients with pituitary adenomas pre- and post-surgery.

2. Comparative study of optic disc changes in ischemic optic neuropathy versus optic neuritis using optical coherence tomography.

3. Observational study on ocular manifestations in patients with intracranial hypertension.

4. Evaluation of cranial nerve involvement in diabetic and hypertensive patients presenting with diplopia.

5. Cross-sectional study on visual pathway abnormalities in multiple sclerosis using visual evoked potentials.

6. Comparative study of pupillary abnormalities in pharmacologic versus neurologic anisocoria.

7. Observational study of visual symptoms in patients with migraine with aura.

8. Evaluation of oculomotor abnormalities in patients with Parkinson’s disease.

9. Comparative study of treatment outcomes in idiopathic intracranial hypertension with and without lumbar puncture.

10. Cross-sectional study on prevalence of optic atrophy in chronic renal disease patients.

8. Oculoplasty and Orbit

1. Cross-sectional study on pattern of orbital tumors in a tertiary referral center in India.

2. Comparative study of surgical outcomes in external versus endonasal dacryocystorhinostomy.

3. Observational study of ocular prosthesis use and psychosocial impact in post-enucleation patients.

4. Prospective study on outcomes of upper eyelid reconstruction using different flaps post-tumor excision.

5. Comparative study of eyelid laxity procedures in involutional entropion versus ectropion.

6. Cross-sectional study on cosmetic disfigurement and quality of life in patients with thyroid eye disease.

7. Observational study of congenital ptosis and associated ocular abnormalities.

8. Evaluation of orbital imaging in diagnosis of proptosis in pediatric versus adult patients.

9. Comparative study of surgical outcomes in dermoid cyst excision by anterior versus lateral orbitotomy.

10. Cross-sectional study on prevalence and impact of blepharospasm in elderly population.

9. Refractive Errors and Low Vision

1. Cross-sectional study on pattern of refractive errors and compliance to spectacle use in rural school children.

2. Comparative study of visual outcomes and patient satisfaction between LASIK and SMILE procedures.

3. Observational study on the effect of uncorrected refractive errors on academic performance in adolescents.

4. Cross-sectional study on awareness and usage of low vision aids among visually impaired adults.

5. Comparative study of visual rehabilitation outcomes using optical versus electronic magnification in low vision patients.

6. Prospective study on change in refractive error pattern in children with progressive myopia over three years.

7. Cross-sectional analysis of astigmatism types in Indian cataract surgery candidates.

8. Observational study on prevalence and associated factors of presbyopia in an urban working population.

9. Comparative study of night driving performance in patients with corrected myopia versus hyperopia.

10. Cross-sectional study of refractive error distribution in tribal versus urban adolescent populations.

10. Recent Studies and Advances in Ophthalmology

1. Prospective observational study on efficacy of gene therapy in patients with Leber congenital amaurosis.

2. Comparative study of artificial intelligence-based screening versus conventional fundus examination for diabetic retinopathy detection.

3. Cross-sectional analysis of teleophthalmology adoption and satisfaction among rural practitioners in India.

4. Evaluation of outcomes of 3D heads-up display system in vitreoretinal surgeries compared to conventional microscope.

5. Prospective study on efficacy and safety of sustained-release dexamethasone implants in non-infectious posterior uveitis.

6. Comparative study of robotic-assisted versus manual cataract surgery in terms of precision and outcomes.

7. Cross-sectional study on knowledge and attitudes towards stem cell therapy among ophthalmologists in India.

8. Observational study on complications of blue light exposure from digital devices among urban youth.

9. Prospective study of corneal endothelial cell changes after femtosecond laser-assisted refractive surgery.

10. Comparative study of optical coherence tomography angiography and fluorescein angiography in diagnosing retinal vascular disorders.