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Choosing the right pathology thesis topics is crucial for academic and professional success. A well-chosen topic ensures relevance, research depth, and potential for future publication. In pathology, thesis topics can be classified under various sections such as histopathology, hematopathology, cytopathology, forensic pathology, and molecular pathology.
Each section offers unique research avenues for postgraduates to explore clinically significant and innovative ideas. Selecting relevant pathology thesis topics also helps in aligning with ongoing departmental studies, making data collection easier and more authentic.
Moreover, a well-researched thesis can later be transformed into a publishable manuscript in reputed medical journals, which is now a mandatory criterion for promotions and faculty appointments in medical colleges. Hence, students must meticulously choose from the available pathology thesis topics to ensure academic excellence and career advancement. Quality pathology thesis topics pave the way for innovation in diagnostics and patient care.
Study of morphological and immunophenotypic patterns in acute leukemias using flow cytometry.
Comparative analysis of peripheral smear and automated counter findings in anemia among pregnant women.
Observational study of platelet indices in dengue fever and their correlation with disease severity.
Evaluation of bone marrow aspiration and biopsy findings in pancytopenia cases.
Study of hematological parameters in patients with chronic kidney disease on hemodialysis.
Assessment of iron studies in microcytic hypochromic anemia and correlation with bone marrow iron grading.
Comparative study of coagulation profile in patients with liver cirrhosis versus healthy controls.
Cross-sectional analysis of hemoglobin variants using HPLC in suspected hemoglobinopathies.
Study of red cell distribution width as a prognostic marker in sepsis.
Evaluation of leukocyte morphological changes in peripheral smear of patients with COVID-19.
Comparative study of conventional Pap smear and liquid-based cytology in screening cervical lesions.
Study of cytomorphological features of thyroid lesions with histopathological correlation.
Evaluation of fine needle aspiration cytology in diagnosing lymph node lesions with histopathological correlation.
Observational study of urine cytology in suspected cases of urothelial carcinoma.
Assessment of the role of cell block preparation in increasing diagnostic yield in effusion cytology.
Comparative study of cytological features in tuberculous versus metastatic lymphadenopathy.
Cross-sectional analysis of atypical squamous cells of undetermined significance in cervical cytology.
Study of cytological grading of breast carcinomas and correlation with histological grade.
Diagnostic utility of immunocytochemistry in serous effusions.
Evaluation of endoscopic ultrasound-guided FNAC in pancreatic lesions.
Comparative analysis of histological patterns in non-neoplastic and neoplastic skin lesions.
Study of endometrial biopsy findings in abnormal uterine bleeding across different age groups.
Evaluation of renal biopsy specimens in patients with nephrotic syndrome: a clinicopathological correlation.
Cross-sectional analysis of inflammatory and neoplastic colorectal lesions from colonoscopic biopsies.
Study of liver biopsies in patients with chronic hepatitis B and C and correlation with serum fibrosis markers.
Observational study of gastric biopsies in dyspeptic patients with emphasis on H. pylori association.
Correlation of histological grading and hormone receptor status in breast carcinoma.
Evaluation of lung biopsies in interstitial lung diseases using ATS/ERS classification.
Histomorphological spectrum of CNS tumors in a tertiary care center.
Comparative study of squamous cell carcinoma and adenocarcinoma of the cervix using tissue architecture and grading.
Study of HER2/neu expression in breast carcinoma and its correlation with clinicopathological parameters.
Evaluation of Ki-67 proliferative index in various grades of gliomas.
Comparative analysis of EGFR expression in lung adenocarcinoma and squamous cell carcinoma.
Study of PD-L1 expression in urothelial carcinoma and correlation with tumor grade and stage.
Immunohistochemical evaluation of p53 and Bcl-2 in colorectal carcinoma.
Observational study of molecular markers in lymphomas using immunohistochemistry.
Correlation of CD117 and DOG1 expression in gastrointestinal stromal tumors with risk stratification.
Study of androgen receptor expression in prostate carcinoma and correlation with Gleason score.
Evaluation of WT1 and Calretinin in distinguishing mesothelioma from adenocarcinoma in pleural biopsies.
Comparative analysis of BRCA mutation status and histopathological features in ovarian cancer patients.
Evaluation of antinuclear antibody patterns in autoimmune connective tissue diseases.
Study of renal biopsies in lupus nephritis with immunofluorescence findings and clinicopathological correlation.
Immunohistochemical study of CD3 and CD20 in classification of non-Hodgkin lymphoma.
Comparative analysis of IgA nephropathy and other glomerulonephritis using immunofluorescence.
Study of CD10 and Bcl-6 expression in follicular lymphoma and its prognostic significance.
Cross-sectional study of autoimmune markers in inflammatory myopathies.
Immunohistochemical expression of hormone receptors in endometrial carcinoma and correlation with tumor grade.
Evaluation of light chain restriction in plasma cell neoplasms using kappa and lambda immunostaining.
Study of complement C3 and C1q deposition in immune complex glomerulonephritis.
Evaluation of HLA-B27 positivity in spondyloarthropathies and correlation with clinical severity.
Comparative study of urine dipstick test and microscopic analysis in diagnosing urinary tract infections.
Evaluation of proteinuria using spot urine protein/creatinine ratio versus 24-hour urine protein.
Cross-sectional study of glycated hemoglobin levels in diabetic patients and their correlation with fasting and postprandial blood sugar.
Study of pre-analytical errors in routine clinical pathology lab and their impact on test results.
Observational study of biological variation in thyroid function tests.
Evaluation of platelet indices in dengue patients and their clinical correlation.
Comparative study of fasting versus random blood sugar in screening for diabetes mellitus.
Analysis of reference intervals of common biochemical parameters in a local adult population.
Study of turnaround time in high-volume diagnostic laboratory and factors affecting it.
Evaluation of CRP and ESR as markers of inflammation in rheumatoid arthritis patients.
Histopathological study of brain tumors with WHO grading and correlation with clinical findings.
Immunohistochemical evaluation of IDH1 and GFAP in gliomas.
Study of morphological features in CNS tuberculomas and their differentiation from neoplasms.
Comparative analysis of meningiomas and schwannomas based on histopathological and immunohistochemical features.
Study of microglial activation in cases of neurodegenerative diseases.
Evaluation of hippocampal sclerosis in patients with intractable epilepsy.
Cross-sectional analysis of brain biopsies in HIV patients with neurological symptoms.
Study of CNS lymphomas with emphasis on CD20 and Ki-67 expression.
Histopathological spectrum of pediatric brain tumors in a tertiary care hospital.
Evaluation of amyloid deposition in Alzheimer’s disease using Congo red and immunohistochemistry.
Study of placental histopathological findings in preeclampsia and eclampsia.
Evaluation of congenital malformations and associated histopathological changes in stillbirth autopsies.
Comparative study of meconium-stained and normal placentas for signs of fetal distress.
Study of autopsy findings in neonatal deaths and their clinical correlation.
Histopathological analysis of pediatric renal biopsies in nephrotic syndrome.
Evaluation of placental changes in gestational diabetes mellitus.
Study of liver histopathology in neonatal cholestasis.
Correlation of birth weight with placental weight and histological findings.
Cross-sectional analysis of pediatric lymph node biopsies for infectious versus neoplastic causes.
Study of histopathological changes in lungs of neonates with respiratory distress syndrome.
Histopathological study of tubercular lymphadenitis with correlation to acid-fast bacilli staining and culture.
Evaluation of liver biopsies in patients with chronic viral hepatitis and fibrosis staging.
Study of granulomatous inflammation in skin biopsies and differential diagnoses.
Comparative study of histological features of fungal and bacterial osteomyelitis.
Cross-sectional analysis of intestinal tuberculosis versus Crohn’s disease in resected specimens.
Study of splenic histopathology in patients with malaria and correlation with parasitemia.
Evaluation of pulmonary biopsy specimens in cases of non-resolving pneumonia.
Histopathological spectrum of HIV-associated opportunistic infections in lymph node biopsies.
Study of renal biopsies in post-infectious glomerulonephritis and correlation with serological markers.
Comparative study of leprosy spectrum using skin biopsy and bacteriological index.
Immunohistochemical evaluation of mismatch repair proteins in colorectal carcinoma for microsatellite instability.
Study of p16 expression in cervical intraepithelial neoplasia and its correlation with HPV status.
Comparative analysis of digital pathology and conventional microscopy in diagnosis of breast lesions.
Evaluation of circulating tumor cells in breast cancer patients and correlation with disease stage.
Study of programmed death ligand-1 (PD-L1) expression in non-small cell lung carcinoma and its therapeutic relevance.
Molecular profiling of sarcomas using next-generation sequencing techniques.
Analysis of liquid biopsy for detection of EGFR mutations in lung carcinoma patients.
Study of artificial intelligence-based image analysis in grading prostate carcinoma.
Role of multiplex PCR in diagnosis of tubercular lymphadenitis from biopsy specimens.
Evaluation of microRNA expression patterns in oral squamous cell carcinoma.
© 2025 Medical Thesis Topics
© 2025 Medical Thesis Topics