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PREMIUM THESIS TOPICS

Pediatric Cardiology Thesis Topics

Below is the current list of 300 free paediatric cardiology thesis topics, covering congenital heart disease both acyanotic and cyanotic, echocardiographic and electrocardiographic reference work, rheumatic fever and rheumatic heart disease, cardiomyopathy and myocarditis, arrhythmias, syncope and childhood hypertension, heart failure and pulmonary hypertension, cardiac changes in systemic disease, and preventive cardiology, for MD and DNB candidates in Paediatrics. These also serve as paediatric cardiology research topics for board residents and postgraduate students outside India. Every title uses a cross-sectional, observational, comparative, diagnostic or analytical design that can be completed within a single thesis period using children already attending the cardiology clinic, the paediatric wards or the echocardiography list, together with investigations already performed for clinical reasons. Each topic generates a complete paediatrics protocol and paediatrics synopsis in editable format.

Last reviewed and updated: August 2026

📌 Updated for 2026–2027 MD and DNB Paediatrics admissions

This list of paediatric cardiology thesis topics is updated for the 2026–27 academic cycle. Topics are reviewed against recent dissertations, examiner preferences, feasibility in Indian district and tertiary paediatric units, and the reporting standards now expected in paediatric echocardiographic research.

  • Designs achievable on the existing echocardiography and electrocardiography list, with no additional sedation or contrast
  • Reference-value and screening topics for units without an interventional cardiology service
  • Strong publication potential, particularly in Indian paediatric Z-score data, rheumatic screening and preventive cardiology
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  • Introduction / Synopsis
  • Research Question
  • Aim of the Study
  • Primary Objective
  • Secondary Objectives
  • Materials and Methods
  • Inclusion Criteria
  • Exclusion Criteria
  • Sample Size Calculation
  • Methodology
  • Statistical Analysis
  • Ethical Considerations
  • Review of Literature
  • References
  • Gantt Chart / Study Timeline
  • Patient Information Sheet
  • Consent Form
  • Data Collection Form

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Congenital Heart Disease: Clinical Profile and Epidemiology

  1. Clinical and Echocardiographic Profile of Congenital Heart Disease among Children Attending a Tertiary Care Hospital: A Cross-Sectional Observational Study
  2. Spectrum of Congenital Heart Disease among Children Presenting to a Paediatric Cardiology Clinic: A Cross-Sectional Observational Study
  3. Prevalence and Pattern of Acyanotic Congenital Heart Disease among Children: A Cross-Sectional Study
  4. Prevalence and Pattern of Cyanotic Congenital Heart Disease among Children: A Cross-Sectional Study
  5. Comparative Evaluation of Clinical Characteristics of Children with Cyanotic and Acyanotic Congenital Heart Disease: A Cross-Sectional Study
  6. Age-Wise Distribution of Different Congenital Heart Defects among Children: A Cross-Sectional Observational Study
  7. Clinical Profile of Congenital Heart Disease Presenting during Infancy: A Cross-Sectional Observational Study
  8. Clinical Profile of Congenital Heart Disease among Preschool Children: A Cross-Sectional Observational Study
  9. Clinical Profile of Congenital Heart Disease among School-Aged Children and Adolescents: A Cross-Sectional Observational Study
  10. Association of Age at Diagnosis with Type and Severity of Congenital Heart Disease among Children: A Cross-Sectional Analytical Study
  11. Pattern of Presenting Symptoms among Children with Congenital Heart Disease: A Cross-Sectional Observational Study
  12. Association of Presenting Symptoms with Anatomical Type of Congenital Heart Disease: A Cross-Sectional Analytical Study
  13. Pattern of Cardiac Murmurs among Children with Echocardiographically Confirmed Congenital Heart Disease: A Cross-Sectional Observational Study
  14. Association of Clinical Murmur Characteristics with Echocardiographic Diagnosis among Children: A Cross-Sectional Analytical Study
  15. Diagnostic Utility of Clinical Examination for Detection of Congenital Heart Disease among Children Referred for Echocardiography: A Cross-Sectional Study
  16. Clinical and Echocardiographic Profile of Congenital Heart Disease among Children with Recurrent Respiratory Infections: A Cross-Sectional Observational Study
  17. Prevalence of Congenital Heart Disease among Children Presenting with Failure to Thrive: A Cross-Sectional Study
  18. Association of Congenital Heart Disease Type with Growth Failure among Children: A Cross-Sectional Analytical Study
  19. Spectrum of Congenital Heart Disease among Children Presenting with Cyanosis: A Cross-Sectional Observational Study
  20. Clinical and Echocardiographic Profile of Children Presenting with Digital Clubbing and Suspected Congenital Heart Disease: A Cross-Sectional Observational Study
  21. Prevalence of Congenital Heart Disease among Children with Genetic and Chromosomal Syndromes: A Cross-Sectional Study
  22. Pattern of Congenital Heart Defects among Children with Down Syndrome: A Cross-Sectional Observational Study
  23. Comparative Evaluation of Congenital Heart Defect Patterns in Syndromic and Non-Syndromic Children: A Cross-Sectional Study
  24. Association of Maternal Risk Factors with Congenital Heart Disease among Children: A Cross-Sectional Analytical Study
  25. Association of Maternal Diabetes Mellitus with Pattern of Congenital Heart Disease among Children: A Cross-Sectional Analytical Study
  26. Association of Parental Consanguinity with Congenital Heart Disease among Children: A Cross-Sectional Analytical Study
  27. Association of Family History of Congenital Heart Disease with Cardiac Defect Patterns among Children: A Cross-Sectional Analytical Study
  28. Extracardiac Congenital Anomalies among Children with Congenital Heart Disease: A Cross-Sectional Observational Study
  29. Comparative Evaluation of Extracardiac Anomalies in Cyanotic and Acyanotic Congenital Heart Disease: A Cross-Sectional Study
  30. Clinical, Demographic and Echocardiographic Spectrum of Congenital Heart Disease among Children at a Tertiary Care Centre: A Cross-Sectional Observational Study

Acyanotic Congenital Heart Disease

  1. Clinical and Echocardiographic Profile of Ventricular Septal Defect among Children: A Cross-Sectional Observational Study
  2. Distribution of Anatomical Types of Ventricular Septal Defect among Children: A Cross-Sectional Study
  3. Association of Ventricular Septal Defect Size with Clinical Symptoms among Children: A Cross-Sectional Analytical Study
  4. Association of Ventricular Septal Defect Size with Growth Parameters among Children: A Cross-Sectional Analytical Study
  5. Comparative Evaluation of Clinical Features in Children with Small and Large Ventricular Septal Defects: A Cross-Sectional Study
  6. Pulmonary Artery Pressure Profile among Children with Ventricular Septal Defect: A Cross-Sectional Observational Study
  7. Association of Ventricular Septal Defect Size with Pulmonary Artery Pressure: A Cross-Sectional Analytical Study
  8. Clinical and Echocardiographic Profile of Atrial Septal Defect among Children: A Cross-Sectional Observational Study
  9. Distribution of Anatomical Types of Atrial Septal Defect among Children: A Cross-Sectional Study
  10. Association of Atrial Septal Defect Size with Right Ventricular Dimensions among Children: A Cross-Sectional Analytical Study
  11. Comparative Evaluation of Clinical and Echocardiographic Characteristics of Different Types of Atrial Septal Defect: A Cross-Sectional Study
  12. Pulmonary Artery Pressure Profile among Children with Atrial Septal Defect: A Cross-Sectional Observational Study
  13. Clinical and Echocardiographic Profile of Patent Ductus Arteriosus among Children: A Cross-Sectional Observational Study
  14. Association of Patent Ductus Arteriosus Size with Clinical Severity among Children: A Cross-Sectional Analytical Study
  15. Association of Patent Ductus Arteriosus Size with Pulmonary Artery Pressure: A Cross-Sectional Analytical Study
  16. Comparative Evaluation of Clinical Characteristics of Small and Haemodynamically Significant Patent Ductus Arteriosus: A Cross-Sectional Study
  17. Clinical and Echocardiographic Profile of Atrioventricular Septal Defect among Children: A Cross-Sectional Observational Study
  18. Comparative Evaluation of Partial and Complete Atrioventricular Septal Defects among Children: A Cross-Sectional Study
  19. Association of Atrioventricular Septal Defect with Nutritional Status among Children: A Cross-Sectional Analytical Study
  20. Clinical and Echocardiographic Profile of Pulmonary Valve Stenosis among Children: A Cross-Sectional Observational Study
  21. Association of Pulmonary Valve Gradient with Clinical Characteristics among Children with Pulmonary Stenosis: A Cross-Sectional Analytical Study
  22. Comparative Evaluation of Mild, Moderate and Severe Pulmonary Valve Stenosis among Children: A Cross-Sectional Study
  23. Clinical and Echocardiographic Profile of Aortic Stenosis among Children: A Cross-Sectional Observational Study
  24. Association of Aortic Valve Gradient with Left Ventricular Hypertrophy among Children with Aortic Stenosis: A Cross-Sectional Analytical Study
  25. Clinical and Echocardiographic Profile of Coarctation of the Aorta among Children: A Cross-Sectional Observational Study
  26. Association of Upper-Lower Limb Blood Pressure Gradient with Echocardiographic Severity of Coarctation of the Aorta: A Cross-Sectional Analytical Study
  27. Comparative Evaluation of Growth Parameters in Children with Ventricular Septal Defect, Atrial Septal Defect and Patent Ductus Arteriosus: A Cross-Sectional Study
  28. Comparative Evaluation of Pulmonary Artery Pressure in Common Acyanotic Congenital Heart Defects: A Cross-Sectional Study
  29. Electrocardiographic Patterns among Children with Common Acyanotic Congenital Heart Disease: A Cross-Sectional Observational Study
  30. Clinical and Echocardiographic Spectrum of Acyanotic Congenital Heart Disease among Children: A Cross-Sectional Observational Study

Cyanotic Congenital Heart Disease

  1. Clinical and Echocardiographic Profile of Tetralogy of Fallot among Children: A Cross-Sectional Observational Study
  2. Age and Clinical Presentation of Children with Tetralogy of Fallot at a Tertiary Care Hospital: A Cross-Sectional Study
  3. Association of Oxygen Saturation with Haemoglobin and Haematocrit Levels among Children with Tetralogy of Fallot: A Cross-Sectional Analytical Study
  4. Association of Severity of Right Ventricular Outflow Tract Obstruction with Oxygen Saturation among Children with Tetralogy of Fallot: A Cross-Sectional Analytical Study
  5. Comparative Evaluation of Growth Parameters in Children with Tetralogy of Fallot and Acyanotic Congenital Heart Disease: A Cross-Sectional Study
  6. Prevalence and Severity of Secondary Erythrocytosis among Children with Cyanotic Congenital Heart Disease: A Cross-Sectional Study
  7. Association of Oxygen Saturation with Haematological Parameters among Children with Cyanotic Congenital Heart Disease: A Cross-Sectional Analytical Study
  8. Iron Status among Children with Cyanotic Congenital Heart Disease: A Cross-Sectional Observational Study
  9. Prevalence of Iron Deficiency among Children with Cyanotic Congenital Heart Disease: A Cross-Sectional Study
  10. Association of Iron Deficiency with Hyperviscosity Symptoms among Children with Cyanotic Congenital Heart Disease: A Cross-Sectional Analytical Study
  11. Clinical and Echocardiographic Profile of Transposition of the Great Arteries among Children: A Cross-Sectional Observational Study
  12. Clinical and Echocardiographic Profile of Tricuspid Atresia among Children: A Cross-Sectional Observational Study
  13. Clinical and Echocardiographic Profile of Pulmonary Atresia among Children: A Cross-Sectional Observational Study
  14. Clinical and Echocardiographic Profile of Total Anomalous Pulmonary Venous Connection among Children: A Cross-Sectional Observational Study
  15. Comparative Evaluation of Clinical Characteristics of Tetralogy of Fallot and Other Cyanotic Congenital Heart Diseases: A Cross-Sectional Study
  16. Prevalence of Digital Clubbing among Children with Cyanotic Congenital Heart Disease: A Cross-Sectional Study
  17. Association of Digital Clubbing Severity with Oxygen Saturation among Children with Cyanotic Congenital Heart Disease: A Cross-Sectional Analytical Study
  18. Growth and Nutritional Status among Children with Cyanotic Congenital Heart Disease: A Cross-Sectional Observational Study
  19. Association of Chronic Hypoxaemia with Growth Failure among Children with Cyanotic Congenital Heart Disease: A Cross-Sectional Analytical Study
  20. Comparative Evaluation of Nutritional Status in Cyanotic and Acyanotic Congenital Heart Disease: A Cross-Sectional Study
  21. Renal Function Profile among Children with Cyanotic Congenital Heart Disease: A Cross-Sectional Observational Study
  22. Association of Haematocrit with Renal Function Parameters among Children with Cyanotic Congenital Heart Disease: A Cross-Sectional Analytical Study
  23. Coagulation Profile among Children with Cyanotic Congenital Heart Disease: A Cross-Sectional Observational Study
  24. Association of Oxygen Saturation with Coagulation Parameters among Children with Cyanotic Congenital Heart Disease: A Cross-Sectional Analytical Study
  25. Platelet Count and Platelet Indices among Children with Cyanotic Congenital Heart Disease: A Cross-Sectional Study
  26. Electrocardiographic Patterns among Children with Tetralogy of Fallot: A Cross-Sectional Observational Study
  27. Chest Radiographic Findings among Children with Cyanotic Congenital Heart Disease: A Cross-Sectional Observational Study
  28. Comparative Evaluation of Haematological Abnormalities among Different Cyanotic Congenital Heart Defects: A Cross-Sectional Study
  29. Clinical Profile of Hypercyanotic Spells among Children with Tetralogy of Fallot: A Cross-Sectional Observational Study
  30. Clinical, Haematological and Echocardiographic Spectrum of Cyanotic Congenital Heart Disease among Children: A Cross-Sectional Observational Study

Paediatric Echocardiography, Electrocardiography and Cardiac Imaging

  1. Echocardiographic Reference Values of Left Ventricular Dimensions among Healthy Children: A Cross-Sectional Observational Study
  2. Association of Left Ventricular Dimensions with Age, Height, Weight and Body Surface Area among Children: A Cross-Sectional Analytical Study
  3. Echocardiographic Assessment of Left Ventricular Systolic Function among Healthy Children: A Cross-Sectional Observational Study
  4. Comparative Evaluation of Left Ventricular Systolic Function across Different Paediatric Age Groups: A Cross-Sectional Study
  5. Echocardiographic Assessment of Left Ventricular Diastolic Function among Healthy Children: A Cross-Sectional Observational Study
  6. Association of Left Ventricular Diastolic Parameters with Age and Body Surface Area among Children: A Cross-Sectional Analytical Study
  7. Echocardiographic Evaluation of Right Ventricular Dimensions among Healthy Children: A Cross-Sectional Observational Study
  8. Association of Right Ventricular Dimensions with Anthropometric Parameters among Children: A Cross-Sectional Analytical Study
  9. Echocardiographic Assessment of Right Ventricular Systolic Function among Children Using Tricuspid Annular Plane Systolic Excursion: A Cross-Sectional Study
  10. Association of Tricuspid Annular Plane Systolic Excursion with Age and Body Surface Area among Healthy Children: A Cross-Sectional Analytical Study
  11. Echocardiographic Assessment of Pulmonary Artery Dimensions among Healthy Children: A Cross-Sectional Observational Study
  12. Association of Aortic Root Dimensions with Age, Height and Body Surface Area among Children: A Cross-Sectional Analytical Study
  13. Comparative Evaluation of Aortic Root and Pulmonary Artery Dimensions across Paediatric Age Groups: A Cross-Sectional Study
  14. Echocardiographic Assessment of Left Atrial Dimensions among Healthy Children: A Cross-Sectional Observational Study
  15. Association of Left Atrial Size with Age and Body Surface Area among Children: A Cross-Sectional Analytical Study
  16. Echocardiographic Evaluation of Inferior Vena Cava Diameter and Collapsibility among Healthy Children: A Cross-Sectional Study
  17. Association of Inferior Vena Cava Diameter with Age and Body Surface Area among Children: A Cross-Sectional Analytical Study
  18. Electrocardiographic Parameters among Healthy School-Aged Children: A Cross-Sectional Observational Study
  19. Comparative Evaluation of Electrocardiographic Parameters across Different Paediatric Age Groups: A Cross-Sectional Study
  20. Association of Electrocardiographic Intervals with Age, Sex and Anthropometric Parameters among Children: A Cross-Sectional Analytical Study
  21. Prevalence and Pattern of Incidental Electrocardiographic Abnormalities among Apparently Healthy School Children: A Cross-Sectional Study
  22. Electrocardiographic Profile of Children with Congenital Heart Disease: A Cross-Sectional Observational Study
  23. Association of Electrocardiographic Ventricular Hypertrophy Criteria with Echocardiographic Findings among Children: A Cross-Sectional Analytical Study
  24. Comparative Evaluation of Electrocardiographic and Echocardiographic Detection of Left Ventricular Hypertrophy in Children: A Cross-Sectional Study
  25. Comparative Evaluation of Electrocardiographic and Echocardiographic Detection of Right Ventricular Hypertrophy in Children: A Cross-Sectional Study
  26. Diagnostic Utility of Chest Radiography in Children with Suspected Congenital Heart Disease: A Cross-Sectional Study
  27. Association of Cardiothoracic Ratio on Chest Radiography with Echocardiographic Cardiac Dimensions among Children: A Cross-Sectional Analytical Study
  28. Echocardiographic Profile of Children Referred for Evaluation of an Asymptomatic Cardiac Murmur: A Cross-Sectional Observational Study
  29. Diagnostic Yield of Echocardiography among Children with Asymptomatic Cardiac Murmurs: A Cross-Sectional Study
  30. Clinical and Imaging Correlation among Children Referred for Suspected Structural Heart Disease: A Cross-Sectional Analytical Study

Rheumatic Fever and Rheumatic Heart Disease

  1. Clinical and Echocardiographic Profile of Acute Rheumatic Fever among Children: A Cross-Sectional Observational Study
  2. Spectrum of Cardiac Involvement among Children with Acute Rheumatic Fever: A Cross-Sectional Study
  3. Prevalence and Pattern of Carditis among Children with Acute Rheumatic Fever: A Cross-Sectional Observational Study
  4. Association of Clinical Features with Echocardiographic Carditis among Children with Acute Rheumatic Fever: A Cross-Sectional Analytical Study
  5. Comparative Evaluation of Clinical and Subclinical Carditis among Children with Acute Rheumatic Fever: A Cross-Sectional Study
  6. Prevalence and Pattern of Valvular Involvement among Children with Rheumatic Heart Disease: A Cross-Sectional Study
  7. Comparative Evaluation of Mitral and Aortic Valve Involvement among Children with Rheumatic Heart Disease: A Cross-Sectional Study
  8. Echocardiographic Severity of Mitral Regurgitation among Children with Rheumatic Heart Disease: A Cross-Sectional Observational Study
  9. Association of Mitral Regurgitation Severity with Clinical Symptoms among Children with Rheumatic Heart Disease: A Cross-Sectional Analytical Study
  10. Echocardiographic Profile of Aortic Regurgitation among Children with Rheumatic Heart Disease: A Cross-Sectional Observational Study
  11. Comparative Evaluation of Isolated and Multivalvular Rheumatic Heart Disease among Children: A Cross-Sectional Study
  12. Left Ventricular Dimensions and Function among Children with Rheumatic Mitral Regurgitation: A Cross-Sectional Study
  13. Association of Valvular Disease Severity with Left Ventricular Function among Children with Rheumatic Heart Disease: A Cross-Sectional Analytical Study
  14. Pulmonary Artery Pressure Profile among Children with Rheumatic Heart Disease: A Cross-Sectional Observational Study
  15. Association of Pulmonary Hypertension with Severity of Rheumatic Valvular Disease among Children: A Cross-Sectional Analytical Study
  16. Electrocardiographic Abnormalities among Children with Acute Rheumatic Fever: A Cross-Sectional Observational Study
  17. Association of Electrocardiographic Abnormalities with Echocardiographic Carditis in Acute Rheumatic Fever: A Cross-Sectional Analytical Study
  18. Clinical Profile of Sydenham Chorea among Children with Acute Rheumatic Fever: A Cross-Sectional Observational Study
  19. Association of Sydenham Chorea with Echocardiographic Valvular Abnormalities among Children: A Cross-Sectional Analytical Study
  20. Clinical Profile of Arthritis among Children with Acute Rheumatic Fever: A Cross-Sectional Observational Study
  21. Comparative Evaluation of Children with First-Episode and Recurrent Acute Rheumatic Fever: A Cross-Sectional Study
  22. Nutritional Status among Children with Rheumatic Heart Disease: A Cross-Sectional Observational Study
  23. Association of Rheumatic Heart Disease Severity with Growth Parameters among Children: A Cross-Sectional Analytical Study
  24. Knowledge and Practices Regarding Secondary Prophylaxis among Caregivers of Children with Rheumatic Heart Disease: A Cross-Sectional Study
  25. Adherence to Secondary Prophylaxis among Children with Rheumatic Heart Disease: A Cross-Sectional Study
  26. Factors Associated with Poor Adherence to Secondary Prophylaxis among Children with Rheumatic Heart Disease: A Cross-Sectional Analytical Study
  27. Health-Related Quality of Life among Children and Adolescents with Rheumatic Heart Disease: A Cross-Sectional Study
  28. Association of Disease Severity with Quality of Life among Children with Rheumatic Heart Disease: A Cross-Sectional Analytical Study
  29. School Attendance and Academic Difficulties among Children with Rheumatic Heart Disease: A Cross-Sectional Observational Study
  30. Clinical, Echocardiographic and Psychosocial Profile of Paediatric Rheumatic Heart Disease: A Cross-Sectional Observational Study

Acquired Heart Disease, Myocarditis and Cardiomyopathy

  1. Clinical and Echocardiographic Profile of Cardiomyopathy among Children: A Cross-Sectional Observational Study
  2. Spectrum of Cardiomyopathies among Children Attending a Paediatric Cardiology Centre: A Cross-Sectional Study
  3. Clinical Profile of Dilated Cardiomyopathy among Children: A Cross-Sectional Observational Study
  4. Echocardiographic Characteristics of Dilated Cardiomyopathy among Children: A Cross-Sectional Study
  5. Association of Left Ventricular Ejection Fraction with Clinical Severity among Children with Dilated Cardiomyopathy: A Cross-Sectional Analytical Study
  6. Nutritional Status among Children with Dilated Cardiomyopathy: A Cross-Sectional Observational Study
  7. Association of Growth Failure with Severity of Ventricular Dysfunction among Children with Dilated Cardiomyopathy: A Cross-Sectional Analytical Study
  8. Electrocardiographic Abnormalities among Children with Dilated Cardiomyopathy: A Cross-Sectional Observational Study
  9. Comparative Evaluation of Electrocardiographic and Echocardiographic Abnormalities among Children with Dilated Cardiomyopathy: A Cross-Sectional Study
  10. Clinical and Echocardiographic Profile of Hypertrophic Cardiomyopathy among Children: A Cross-Sectional Observational Study
  11. Association of Left Ventricular Hypertrophy Severity with Clinical Characteristics in Paediatric Hypertrophic Cardiomyopathy: A Cross-Sectional Analytical Study
  12. Comparative Evaluation of Dilated and Hypertrophic Cardiomyopathy among Children: A Cross-Sectional Study
  13. Clinical and Echocardiographic Profile of Suspected Myocarditis among Children: A Cross-Sectional Observational Study
  14. Electrocardiographic Abnormalities among Children with Myocarditis: A Cross-Sectional Observational Study
  15. Association of Cardiac Biomarkers with Ventricular Function among Children with Myocarditis: A Cross-Sectional Analytical Study
  16. Comparative Evaluation of Cardiac Biomarkers in Children with Myocarditis and Non-Cardiac Febrile Illness: A Cross-Sectional Study
  17. Clinical and Echocardiographic Profile of Pericardial Effusion among Children: A Cross-Sectional Observational Study
  18. Aetiological Spectrum of Pericardial Effusion among Children: A Cross-Sectional Study
  19. Association of Pericardial Effusion Size with Clinical Features among Children: A Cross-Sectional Analytical Study
  20. Clinical and Echocardiographic Profile of Tuberculous Pericardial Disease among Children: A Cross-Sectional Observational Study
  21. Cardiac Involvement among Children with Multisystem Inflammatory Syndrome: A Cross-Sectional Observational Study
  22. Echocardiographic Abnormalities among Children with Multisystem Inflammatory Syndrome: A Cross-Sectional Study
  23. Association of Inflammatory Markers with Cardiac Dysfunction among Children with Multisystem Inflammatory Syndrome: A Cross-Sectional Analytical Study
  24. Coronary Artery Abnormalities among Children with Kawasaki Disease: A Cross-Sectional Observational Study
  25. Association of Clinical Characteristics with Coronary Artery Abnormalities among Children with Kawasaki Disease: A Cross-Sectional Analytical Study
  26. Comparative Evaluation of Children with Kawasaki Disease with and without Coronary Artery Involvement: A Cross-Sectional Study
  27. Echocardiographic Profile of Cardiac Involvement among Children with Chronic Kidney Disease: A Cross-Sectional Observational Study
  28. Cardiac Abnormalities among Children with Chronic Anaemia: A Cross-Sectional Observational Study
  29. Comparative Evaluation of Cardiac Function among Children with Chronic Anaemia and Healthy Children: A Cross-Sectional Study
  30. Clinical and Echocardiographic Spectrum of Acquired Heart Disease among Children: A Cross-Sectional Observational Study

Paediatric Arrhythmias, Syncope and Hypertension

  1. Clinical and Electrocardiographic Profile of Arrhythmias among Children: A Cross-Sectional Observational Study
  2. Spectrum of Cardiac Rhythm Abnormalities among Children Referred for Electrocardiography: A Cross-Sectional Study
  3. Clinical Profile of Supraventricular Tachycardia among Children: A Cross-Sectional Observational Study
  4. Electrocardiographic Characteristics of Supraventricular Tachycardia among Children: A Cross-Sectional Study
  5. Comparative Evaluation of Arrhythmia Patterns among Children with and without Structural Heart Disease: A Cross-Sectional Study
  6. Prevalence and Pattern of Electrocardiographic Abnormalities among Children Presenting with Palpitations: A Cross-Sectional Study
  7. Association of Palpitation Characteristics with Electrocardiographic Findings among Children: A Cross-Sectional Analytical Study
  8. Clinical Profile of Children Presenting with Syncope to a Tertiary Care Hospital: A Cross-Sectional Observational Study
  9. Aetiological Spectrum of Syncope among Children and Adolescents: A Cross-Sectional Study
  10. Prevalence of Cardiac Causes among Children Presenting with Syncope: A Cross-Sectional Study
  11. Electrocardiographic Abnormalities among Children Presenting with Syncope: A Cross-Sectional Observational Study
  12. Comparative Evaluation of Clinical Characteristics of Cardiac and Non-Cardiac Syncope among Children: A Cross-Sectional Study
  13. Diagnostic Yield of Electrocardiography among Children Presenting with Syncope: A Cross-Sectional Study
  14. Clinical and Electrocardiographic Profile of Prolonged Corrected QT Interval among Children: A Cross-Sectional Observational Study
  15. Association of Serum Electrolyte Abnormalities with Corrected QT Interval among Hospitalised Children: A Cross-Sectional Analytical Study
  16. Prevalence of Hypertension among School-Aged Children and Adolescents: A Cross-Sectional Study
  17. Association of Childhood Hypertension with Body Mass Index: A Cross-Sectional Analytical Study
  18. Comparative Evaluation of Blood Pressure among Normal-Weight, Overweight and Obese Children: A Cross-Sectional Study
  19. Association of Waist Circumference with Elevated Blood Pressure among School-Aged Children: A Cross-Sectional Analytical Study
  20. Association of Family History of Hypertension with Blood Pressure among Adolescents: A Cross-Sectional Analytical Study
  21. Association of Dietary Salt Intake with Blood Pressure among School-Aged Children: A Cross-Sectional Analytical Study
  22. Association of Physical Activity with Blood Pressure among Adolescents: A Cross-Sectional Analytical Study
  23. Association of Screen Time with Elevated Blood Pressure among School-Aged Children: A Cross-Sectional Analytical Study
  24. Comparative Evaluation of Blood Pressure in Urban and Rural School Children: A Cross-Sectional Study
  25. Prevalence of White-Coat Hypertension among Children Referred for Elevated Clinic Blood Pressure: A Cross-Sectional Study
  26. Clinical and Aetiological Profile of Secondary Hypertension among Children: A Cross-Sectional Observational Study
  27. Echocardiographic Assessment of Left Ventricular Mass among Children with Hypertension: A Cross-Sectional Study
  28. Association of Blood Pressure Severity with Left Ventricular Mass among Hypertensive Children: A Cross-Sectional Analytical Study
  29. Prevalence of Left Ventricular Hypertrophy among Children with Hypertension: A Cross-Sectional Study
  30. Cardiovascular Risk Profile among Overweight and Obese Children with Elevated Blood Pressure: A Cross-Sectional Observational Study

Heart Failure and Pulmonary Hypertension

  1. Clinical Profile of Heart Failure among Children Admitted to a Tertiary Care Hospital: A Cross-Sectional Observational Study
  2. Aetiological Spectrum of Heart Failure among Children: A Cross-Sectional Study
  3. Comparative Evaluation of Heart Failure Characteristics in Children with Congenital and Acquired Heart Disease: A Cross-Sectional Study
  4. Clinical and Echocardiographic Correlates of Heart Failure Severity among Children: A Cross-Sectional Analytical Study
  5. Association of Left Ventricular Ejection Fraction with Clinical Heart Failure Severity among Children: A Cross-Sectional Analytical Study
  6. Association of Nutritional Status with Severity of Heart Failure among Children: A Cross-Sectional Analytical Study
  7. Prevalence of Growth Failure among Children with Chronic Heart Failure: A Cross-Sectional Study
  8. Haematological Profile of Children with Heart Failure: A Cross-Sectional Observational Study
  9. Prevalence of Anaemia among Children with Heart Failure and Its Association with Clinical Severity: A Cross-Sectional Analytical Study
  10. Serum Electrolyte Abnormalities among Children with Heart Failure: A Cross-Sectional Observational Study
  11. Renal Function Profile among Children with Heart Failure: A Cross-Sectional Observational Study
  12. Association of Renal Dysfunction with Severity of Paediatric Heart Failure: A Cross-Sectional Analytical Study
  13. Liver Function Abnormalities among Children with Heart Failure: A Cross-Sectional Observational Study
  14. Association of Hepatic Dysfunction with Clinical Severity of Heart Failure among Children: A Cross-Sectional Analytical Study
  15. Electrocardiographic Abnormalities among Children with Heart Failure: A Cross-Sectional Observational Study
  16. Chest Radiographic Findings among Children with Heart Failure: A Cross-Sectional Observational Study
  17. Association of Cardiothoracic Ratio with Echocardiographic Ventricular Dysfunction among Children with Heart Failure: A Cross-Sectional Analytical Study
  18. Clinical and Echocardiographic Profile of Pulmonary Hypertension among Children: A Cross-Sectional Observational Study
  19. Aetiological Spectrum of Pulmonary Hypertension among Children: A Cross-Sectional Study
  20. Prevalence of Pulmonary Hypertension among Children with Congenital Heart Disease: A Cross-Sectional Study
  21. Comparative Evaluation of Pulmonary Hypertension in Different Left-to-Right Shunt Lesions among Children: A Cross-Sectional Study
  22. Association of Shunt Defect Size with Pulmonary Artery Pressure among Children: A Cross-Sectional Analytical Study
  23. Association of Oxygen Saturation with Pulmonary Artery Pressure among Children with Congenital Heart Disease: A Cross-Sectional Analytical Study
  24. Echocardiographic Assessment of Right Ventricular Function among Children with Pulmonary Hypertension: A Cross-Sectional Study
  25. Association of Pulmonary Artery Pressure with Right Ventricular Function among Children: A Cross-Sectional Analytical Study
  26. Comparative Evaluation of Right Ventricular Function in Children with and without Pulmonary Hypertension: A Cross-Sectional Study
  27. Nutritional Status among Children with Pulmonary Hypertension: A Cross-Sectional Observational Study
  28. Association of Pulmonary Hypertension Severity with Growth Parameters among Children: A Cross-Sectional Analytical Study
  29. Functional Status and Quality of Life among Children with Pulmonary Hypertension: A Cross-Sectional Study
  30. Clinical and Echocardiographic Spectrum of Paediatric Heart Failure and Pulmonary Hypertension: A Cross-Sectional Observational Study

Nutrition, Growth and Systemic Disease-Related Cardiac Changes

  1. Nutritional Status among Children with Congenital Heart Disease: A Cross-Sectional Observational Study
  2. Prevalence of Underweight, Stunting and Wasting among Children with Congenital Heart Disease: A Cross-Sectional Study
  3. Comparative Evaluation of Growth Parameters in Children with Cyanotic and Acyanotic Congenital Heart Disease: A Cross-Sectional Study
  4. Association of Oxygen Saturation with Growth Parameters among Children with Congenital Heart Disease: A Cross-Sectional Analytical Study
  5. Association of Heart Failure Severity with Nutritional Status among Children with Congenital Heart Disease: A Cross-Sectional Analytical Study
  6. Dietary Intake and Its Association with Nutritional Status among Children with Congenital Heart Disease: A Cross-Sectional Analytical Study
  7. Prevalence of Anaemia among Children with Congenital Heart Disease: A Cross-Sectional Study
  8. Comparative Evaluation of Haematological Parameters in Cyanotic and Acyanotic Congenital Heart Disease: A Cross-Sectional Study
  9. Iron Status among Children with Congenital Heart Disease: A Cross-Sectional Observational Study
  10. Association of Iron Deficiency with Growth Failure among Children with Congenital Heart Disease: A Cross-Sectional Analytical Study
  11. Vitamin D Status among Children with Congenital Heart Disease: A Cross-Sectional Observational Study
  12. Association of Vitamin D Levels with Cardiac Function among Children with Congenital Heart Disease: A Cross-Sectional Analytical Study
  13. Echocardiographic Assessment of Cardiac Function among Children with Severe Acute Malnutrition: A Cross-Sectional Observational Study
  14. Comparative Evaluation of Cardiac Function in Children with Severe Acute Malnutrition and Normally Nourished Children: A Cross-Sectional Study
  15. Association of Severity of Malnutrition with Left Ventricular Function among Children: A Cross-Sectional Analytical Study
  16. Echocardiographic Changes among Children with Iron Deficiency Anaemia: A Cross-Sectional Observational Study
  17. Association of Haemoglobin Concentration with Left Ventricular Dimensions among Children with Anaemia: A Cross-Sectional Analytical Study
  18. Cardiac Function among Children with Sickle Cell Disease: A Cross-Sectional Observational Study
  19. Echocardiographic Abnormalities among Children with Transfusion-Dependent Beta Thalassaemia: A Cross-Sectional Study
  20. Association of Serum Ferritin Levels with Cardiac Function among Children with Transfusion-Dependent Beta Thalassaemia: A Cross-Sectional Analytical Study
  21. Echocardiographic Profile of Children with Chronic Kidney Disease: A Cross-Sectional Observational Study
  22. Prevalence of Left Ventricular Hypertrophy among Children with Chronic Kidney Disease: A Cross-Sectional Study
  23. Association of Blood Pressure with Left Ventricular Mass among Children with Chronic Kidney Disease: A Cross-Sectional Analytical Study
  24. Cardiac Function among Children with Nephrotic Syndrome: A Cross-Sectional Observational Study
  25. Echocardiographic Abnormalities among Children with Systemic Lupus Erythematosus: A Cross-Sectional Observational Study
  26. Cardiac Involvement among Children with Juvenile Idiopathic Arthritis: A Cross-Sectional Observational Study
  27. Echocardiographic Assessment of Cardiac Function among Children with Type 1 Diabetes Mellitus: A Cross-Sectional Study
  28. Association of Glycaemic Control with Cardiac Function among Children with Type 1 Diabetes Mellitus: A Cross-Sectional Analytical Study
  29. Cardiovascular Risk Factors among Overweight and Obese Children: A Cross-Sectional Observational Study
  30. Association of Childhood Obesity with Echocardiographic Cardiac Structural and Functional Parameters: A Cross-Sectional Analytical Study

Preventive Cardiology, Quality of Life and Caregiver Perspectives

  1. Cardiovascular Risk Factor Profile among School-Aged Children and Adolescents: A Cross-Sectional Observational Study
  2. Prevalence of Overweight, Obesity and Elevated Blood Pressure among School-Aged Children: A Cross-Sectional Study
  3. Association of Body Mass Index with Blood Pressure and Resting Heart Rate among School Children: A Cross-Sectional Analytical Study
  4. Association of Waist-to-Height Ratio with Cardiovascular Risk Factors among Adolescents: A Cross-Sectional Analytical Study
  5. Lipid Profile among Overweight and Obese Children and Adolescents: A Cross-Sectional Observational Study
  6. Comparative Evaluation of Lipid Profile in Obese and Normal-Weight Children: A Cross-Sectional Study
  7. Association of Body Mass Index with Lipid Abnormalities among School-Aged Children: A Cross-Sectional Analytical Study
  8. Association of Physical Activity with Cardiovascular Risk Factors among Adolescents: A Cross-Sectional Analytical Study
  9. Association of Screen Time and Sedentary Behaviour with Cardiovascular Risk Factors among School Children: A Cross-Sectional Analytical Study
  10. Association of Dietary Patterns with Cardiovascular Risk Factors among Adolescents: A Cross-Sectional Analytical Study
  11. Comparative Evaluation of Cardiovascular Risk Factors among Urban and Rural School Children: A Cross-Sectional Study
  12. Family History of Cardiovascular Disease and Its Association with Cardiometabolic Risk Factors among Adolescents: A Cross-Sectional Analytical Study
  13. Knowledge and Practices Regarding Cardiovascular Health among School-Going Adolescents: A Cross-Sectional Study
  14. Knowledge of Congenital Heart Disease among Parents of Affected Children: A Cross-Sectional Study
  15. Caregiver Knowledge Regarding Warning Signs and Home Care of Children with Congenital Heart Disease: A Cross-Sectional Observational Study
  16. Treatment Adherence and Associated Factors among Children with Chronic Heart Disease: A Cross-Sectional Analytical Study
  17. Health-Related Quality of Life among Children with Congenital Heart Disease: A Cross-Sectional Study
  18. Comparative Evaluation of Quality of Life in Children with Cyanotic and Acyanotic Congenital Heart Disease: A Cross-Sectional Study
  19. Association of Disease Severity with Health-Related Quality of Life among Children with Congenital Heart Disease: A Cross-Sectional Analytical Study
  20. Association of Nutritional Status with Quality of Life among Children with Congenital Heart Disease: A Cross-Sectional Analytical Study
  21. School Attendance and Academic Difficulties among Children with Congenital Heart Disease: A Cross-Sectional Observational Study
  22. Association of Functional Limitation with School Absenteeism among Children with Heart Disease: A Cross-Sectional Analytical Study
  23. Psychosocial Problems among Adolescents with Congenital Heart Disease: A Cross-Sectional Observational Study
  24. Caregiver Burden among Parents of Children with Congenital Heart Disease: A Cross-Sectional Study
  25. Factors Associated with Caregiver Burden among Families of Children with Congenital Heart Disease: A Cross-Sectional Analytical Study
  26. Psychological Distress among Parents of Children with Congenital Heart Disease: A Cross-Sectional Observational Study
  27. Association of Disease Severity with Parental Psychological Distress among Children with Congenital Heart Disease: A Cross-Sectional Analytical Study
  28. Knowledge and Practices Regarding Infective Endocarditis Prevention among Caregivers of Children with Heart Disease: A Cross-Sectional Study
  29. Awareness of Long-Term Cardiac Care Requirements among Adolescents with Congenital Heart Disease and Their Caregivers: A Cross-Sectional Study
  30. Clinical, Nutritional, Functional and Psychosocial Profile of Children with Chronic Heart Disease Attending a Tertiary Care Centre: A Cross-Sectional Observational Study

Alongside protocols and synopses, support is also available for departmental presentations, journal club presentations, ethics committee presentations, and posters and oral presentations for medical conferences — for postgraduate residents, board trainees and research scholars across India and the GCC. Prepared by a practising doctor with long experience in medical publishing and thesis supervision.

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Studying outside India?

The topics above work as research questions anywhere — what changes is the document your institution expects. Two different routes, depending on which applies.

Board residents — SCFHS, Arab Board, OMSB, KIMS, QCHP, NHRA, DHA and DOH

Residency programmes across the Gulf carry a mandatory research requirement, and the equivalent of an Indian synopsis is the research proposal submitted to the IRB before a research project begins. The format differs from the Indian one: it additionally requires a Gantt chart, a budget and resources section, and a Declaration of Helsinki statement.

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PhD and Master's candidates — Saudi Arabia, Malaysia, the Gulf and beyond

University graduate programmes generally require a full research proposal of roughly 6,000 to 10,000 words, with an extended literature review, a theoretical framework and a detailed methodology chapter — considerably longer and deeper than a residency proposal. These are written individually, by a medical doctor, with no artificial intelligence generation and no plagiarism, and revised until the supervisor accepts them.

Enquire about a PhD research proposal →

🔥 Trending research areas in paediatric cardiology for 2026–27

Based on recent dissertations, examiner preferences and current practice in paediatric units across India, these are the emerging high-interest areas:

  • Indian paediatric echocardiographic reference values and Z-scores, where most published nomograms remain Western in origin
  • Echocardiographic screening for rheumatic heart disease using the definite and borderline criteria rather than clinical auscultation alone
  • Cardiac function in undernutrition and chronic anaemia, where the choice between raw and body-size-indexed reporting decides the conclusion
  • Blood pressure and cardiometabolic risk in school children, with left ventricular mass as the measurable end-organ outcome

Protocol and synopsis guidance

What a paediatric cardiology protocol must contain

A paediatric cardiology protocol is judged on internal consistency: the research question, objectives, methodology and statistical plan must all describe the same study. The primary objective should be a single measurable endpoint — one prevalence, one comparison, one association, one diagnostic estimate — with everything else demoted to secondary objectives. Beyond that, almost every topic on this page rests on a measurement made on a growing child, and the protocol has to say how that measurement was made comparable.

Nothing measured in millimetres means anything until it is related to body size. Left ventricular dimensions, right ventricular dimensions, aortic root, pulmonary artery, left atrium, tricuspid annular plane systolic excursion, left ventricular mass and inferior vena cava diameter all scale with growth, so a raw value from a four-year-old and a fourteen-year-old cannot sit in the same column. State that measurements are converted to Z-scores or indexed to body surface area, name the body surface area formula — Haycock, Mosteller and DuBois disagree in small children and the Z-score moves with the choice — and name the nomogram or reference dataset with its citation. Where an Indian reference does not exist for the parameter, say that a Western nomogram is being applied and that this is a limitation, which is exactly the gap the reference-value topics on this page are designed to fill.

Pulmonary artery pressure is estimated, not measured, and sometimes cannot be obtained at all. The echocardiographic figure comes from the peak tricuspid regurgitation velocity with an assumed or estimated right atrial pressure, so the protocol must state the method, state the right atrial pressure assumption, and state what was done for the child with no measurable regurgitant jet — who must be reported as unobtainable rather than quietly dropped. Two further cautions matter for the shunt topics. In an unrestrictive ventricular septal defect or a large ductus, the right ventricular systolic pressure reflects systemic pressure transmitted through the defect and is not by itself evidence of pulmonary vascular disease. And a definitive diagnosis of pulmonary hypertension is a catheterisation diagnosis, so objectives and conclusions should read as echocardiographically estimated pulmonary artery pressure rather than as pulmonary hypertension diagnosed.

Blood pressure needs its own methods paragraph. State the device and its validation for paediatric use, the cuff bladder size selected against the child's arm circumference, the arm used, the posture, the rest period before measurement, and the number of readings averaged. State the reference table used to classify the reading, with the age, sex and height percentile lookup, since Indian and international tables give different classifications for the same child. And be honest about what a single visit can establish: hypertension in children is defined on readings from three separate occasions, so a one-visit cross-sectional study reports elevated blood pressure or hypertensive-range readings, not hypertension. The white-coat topic exists precisely because that distinction is real.

Name the criteria edition for rheumatic work. State which revision of the Jones criteria is used, apply the moderate-to-high-risk population provisions that apply in India, and where echocardiographic screening is involved, use the World Heart Federation definite and borderline definitions with their morphological and Doppler requirements. Without them, physiological regurgitation gets counted as rheumatic disease and the prevalence is meaningless. Record whether the diagnosis was clinical, subclinical or both, since the clinical-versus-subclinical carditis topics turn on that single field.

Record the conditions of the study, not just the result. Heart rate belongs in every dataset here, because diastolic indices, ejection fraction and corrected QT all move with it, and Bazett's formula overcorrects in a tachycardic child. State whether the child was sedated, crying, febrile or anaemic at the time. For every echocardiographic parameter, state the view, where in the cardiac cycle the measurement was taken, whether M-mode or two-dimensional measurement was used, and the machine and probe. Name who performed and reported the studies, their level of training, and whether the reporter knew the clinical diagnosis — and for any concordance or diagnostic accuracy topic, state that the reading was independent and blinded. Report intra-observer and inter-observer agreement on a defined subset; in echocardiographic dissertations that subset is the difference between a believable paper and an unpublishable one.

Paediatrics synopsis versus paediatrics protocol

A paediatrics synopsis is the condensed document of two to four pages — title, introduction, aim and objectives, brief methodology, sample size and references — submitted for registration of the dissertation topic. The paediatrics protocol is the expanded version of twelve to twenty pages carrying the full review of literature, detailed methodology including measurement definitions and imaging technique, the statistical plan, the study timeline and the annexures.

Four annexures carry particular weight on this subject. The measurement definition annexure should list every echocardiographic and electrocardiographic parameter with the view or lead, the point in the cardiac cycle, the measurement convention and the units — this is what an examiner checks when reported values differ from published series. The reference and Z-score annexure reproduces the nomogram source, the body surface area formula and the cut-offs applied, including the paediatric electrocardiographic criteria used for ventricular hypertrophy, which are age-specific and not the adult voltage rules. The instrument annexure carries any quality-of-life, adherence or caregiver burden questionnaire with its scoring key and licence correspondence. And the consent set requires a parent or guardian information sheet and consent form in the local language plus a separate age-appropriate assent form.

Two paediatric specifics that examiners look for. Where healthy children are recruited — the reference-value topics, the school-based studies and every comparison group — the protocol must define what healthy means, how it was verified, and what happens when the scan finds a lesion, because in a series of apparently normal children it will. And the protocol must state the sedation position explicitly: whether any child is sedated for the study, and if the unit's practice is to sedate infants for echocardiography, that no child is sedated for research purposes alone.

In practice the synopsis is extracted from the protocol rather than written separately, which is faster and produces a more coherent document. Check the university's prescribed proforma before submission, since rejections on formatting grounds are common and entirely avoidable.

Sample size and statistical analysis

Match the formula to the design. Prevalence topics — congenital heart disease among syndromic children, pulmonary hypertension in shunt lesions, left ventricular hypertrophy in hypertension, elevated blood pressure in school children — use a single proportion formula with an expected prevalence from a cited comparable study and a stated precision. Comparative topics need a two-mean or two-proportion calculation with both expected values referenced. Diagnostic topics are sized on expected sensitivity and specificity, with the number required being the number of children with the target condition, from which the total follows using the expected prevalence in the referred population. Name the citation that supplied the input.

Reference-value studies need far more children than a comparison study, and this is the commonest sizing error on this page. Estimating a mean precisely is easy; estimating a 95th or 5th centile precisely is not, and a nomogram is a statement about the tails. A reference series must also be stratified, because the values change with age and body size, so the sample size applies to each age band rather than to the whole series — sixty children spread across infancy to adolescence produce no usable reference at any age. State the age bands in advance, state the target number per band, and define the healthy population by explicit criteria rather than by absence of complaint.

Correlating a cardiac dimension with age, height, weight or body surface area is guaranteed to succeed and proves nothing. Several topics in the imaging section are worded as associations of that kind, and a Pearson coefficient of 0.8 between left ventricular dimension and body surface area is a restatement of growth, not a finding. Handle them as they are meant to be handled: fit a regression, preferably allometric, report the equation with its coefficient of determination and standard error of estimate, and present predicted values with prediction intervals across the range of body size. That produces a usable nomogram, which is publishable; a correlation coefficient is not.

Indexing to body surface area breaks in exactly the children several topics here study. Dividing a small heart by a small body returns a value that can look normal or high, so a wasted child with genuinely reduced cardiac dimensions may index into the reference range. This is a large part of why published studies of cardiac function in severe acute malnutrition disagree with one another, and it affects the malnutrition, chronic anaemia, cyanotic growth-failure and heart-failure comparisons on this list. Where the comparison group differs systematically in body size from the study group, state the indexing method in the objective, report raw values alongside indexed values, and consider indexing to height rather than body surface area since height is less disturbed by acute weight loss. A conclusion that reverses depending on the denominator must be presented with both denominators.

Distinguish the agreement studies from the accuracy studies, because both appear on this page and they need different analyses. The electrocardiographic versus echocardiographic hypertrophy topics are paired comparisons of two tests on the same child using age-specific paediatric criteria: report agreement as Cohen's kappa alongside sensitivity and specificity, and state which paediatric voltage criteria were applied, since adult rules misclassify children routinely. The clinical examination and chest radiography topics, by contrast, are true diagnostic accuracy studies, because echocardiography is a genuine reference standard for structural disease — report sensitivity, specificity, predictive values and likelihood ratios with confidence intervals, and note that the predictive values belong to the referral population studied. Where two methods measure the same continuous quantity, such as cardiothoracic ratio against echocardiographic dimensions, use Bland-Altman analysis with limits of agreement rather than correlation alone.

Referral filtering runs through the whole page. A spectrum of congenital heart disease compiled from an echocardiography list describes children who were referred for echocardiography, which is determined by who noticed a murmur, who could afford the journey and which lesions survive to reach a tertiary centre. Duct-dependent and severely cyanotic lesions are systematically under-represented in a series drawn from an out-patient clinic, and that is worth stating rather than concluding that the lesion is rare locally. Word prevalence objectives as prevalence among children attending, and keep school-based and hospital-based recruitment analytically separate.

Name the tests. Continuous variables are summarised as mean with standard deviation where normally distributed and median with interquartile range otherwise, with normality formally tested; gradients, ejection fraction and pressure estimates are frequently skewed. Two independent groups use the t-test or Mann-Whitney U test, three or more groups analysis of variance or the Kruskal-Wallis test with a stated post-hoc correction. Proportions use the chi-squared test with Fisher's exact test for sparse cells. Where a study reports twenty echocardiographic parameters across two groups, nominate the primary endpoint in advance and treat the remainder as exploratory or apply a stated correction, because at that width some comparison will reach significance by chance alone.

Frequently Asked Questions – Paediatric Cardiology Thesis Topics (2026–27)

1. How do I choose a feasible paediatric cardiology thesis topic for the 2026–27 academic year?

Start from the echocardiography list. Count how many paediatric studies the unit performs in a year, who performs them, and whether a resident may be present and record measurements. That single fact decides most of this page, because a topic requiring a hundred echocardiograms is straightforward where a paediatric cardiologist runs a weekly list and impossible where children are sent to an adult cardiology department that reports in a sentence.

Then match the topic to what the unit actually sees. Ventricular septal defect, atrial septal defect, patent ductus arteriosus and rheumatic heart disease accumulate in any general paediatric service; transposition, tricuspid atresia and total anomalous pulmonary venous connection do not, and a profile study of a rare lesion in a unit without a cardiac surgical programme will not fill. Cardiac biomarkers, lipid profiles and vitamin D differ in availability and cost. Where a topic needs healthy children — the reference values and the school-based studies — confirm that school permission or a well-child source exists before registering, since that is the arrangement that most often fails after approval.

2. Which study designs are commonly accepted for MD and DNB Paediatrics dissertations in cardiology?

Descriptive clinical and echocardiographic profiles remain the most common and are readily accepted: a defined group of children with a stated lesion, described across clinical, echocardiographic, electrocardiographic and growth parameters. Prevalence studies of a complication within a lesion group, comparative studies between lesions or against healthy children, and analytical studies associating an echocardiographic measurement with a clinical variable are all established.

Two further categories publish particularly well. Reference-value studies in healthy children produce Indian normative data, which is genuinely scarce and citable for years afterwards, and they suit a unit with echocardiography access but few complex cases. Diagnostic accuracy and yield studies — clinical examination against echocardiography, electrocardiography in syncope, echocardiography in asymptomatic murmurs — are accepted and straightforward to write up. Questionnaire-based studies of quality of life, adherence to secondary prophylaxis and caregiver burden are equally acceptable and are often the most feasible option where imaging access is limited.

3. What should I discuss with my guide before finalising the topic?

Bring three to five shortlisted titles rather than one, since guides frequently rule out a topic on grounds a new resident cannot see — a senior resident already attached to the cardiology list, a departmental project on the same register, a machine due for replacement.

Settle six things in that meeting: how many children with the required lesion attend annually and how the count was made; who will perform the echocardiograms, whether their reporting is standardised, and whether they will measure the additional parameters the study needs; which nomogram and body surface area formula the department expects; who will act as second observer for the reliability subset and, where the design requires it, whether blinded independent reporting is possible; whether healthy children or school access are needed and who obtains permission; and which journal the eventual paper is aimed at. Where the topic needs biochemistry, nephrology, endocrinology or a cardiac surgical service, secure that cooperation formally rather than on an informal understanding.

4. Can pulmonary hypertension be diagnosed on echocardiography alone?

Not definitively, and the wording of the objective should reflect that. Echocardiography estimates pulmonary artery systolic pressure from the peak tricuspid regurgitation velocity plus an assumed right atrial pressure; the formal diagnosis rests on mean pulmonary artery pressure measured at catheterisation, which very few thesis populations will have undergone. Word objectives and conclusions as echocardiographically estimated pulmonary artery pressure, and state the assumption used for right atrial pressure.

Three practical points for the twenty or so topics on this page that involve pulmonary artery pressure. Some children yield no measurable jet. Adequate tricuspid regurgitation is absent in a proportion of children, and those children must be reported as unobtainable with a number, not silently excluded, because dropping them biases the series toward higher pressures. A high right ventricular pressure in a large shunt is not automatically pulmonary vascular disease. In an unrestrictive ventricular septal defect or a large ductus, systemic pressure is transmitted to the right ventricle, so the estimate reflects the defect rather than the pulmonary vasculature; state the defect size and restriction status alongside every estimate. Use supporting evidence rather than a single number. Right ventricular size and function, septal configuration, pulmonary acceleration time and right atrial size all belong in the dataset, and a study that reports them reads as competent where one reporting a single derived figure does not.

5. What is the difference between a paediatrics synopsis and a protocol?

The synopsis is the condensed two to four page document submitted for topic registration. The protocol is the full document of twelve to twenty pages containing the detailed review of literature, methodology with measurement definitions and imaging technique, the nomogram and reference cut-offs applied, the statistical plan, the timeline and the annexures including the consent and assent set. The synopsis is normally extracted from the completed protocol.

6. What ethical clearance does a paediatric cardiology dissertation need?

Institutional ethics committee approval before any data collection, under the national ethical guidelines for biomedical research involving human participants and the specific provisions governing research in children. Where school children are studied, written permission from the school authority or education department is required in addition, and committees ask to see it.

Consent and assent. Written informed consent from a parent or legal guardian in the local language, and written assent from the child from about seven years of age. State that participation is voluntary and that refusal does not affect the child's cardiac care or surgical listing — a reassurance that matters to a family waiting for an operation.

Healthy children carry the heaviest justification. A child recruited for a reference-value study gains nothing clinically, so the protocol must justify the burden, keep it minimal, and state plainly that no child is sedated for research and that no additional investigation involving radiation or contrast is performed. Where a scan requires the infant to be settled, state that only children already sedated for clinical indications are included, or that the study is confined to age groups who tolerate it awake.

Incidental findings are certain here, not hypothetical. Screening apparently healthy children with echocardiography and electrocardiography will detect septal defects, bicuspid valves, borderline rheumatic changes, prolonged corrected QT intervals and occasionally something serious. The protocol must state in advance who informs the family, how, and the named referral pathway, including what is done with a borderline finding that may cause anxiety without requiring treatment. The same applies to school blood pressure studies, where a child with hypertensive-range readings needs a route to repeat measurement and assessment rather than a line in a results table.

Confidentiality and images. Echocardiographic and radiographic images carry patient identifiers, which must be removed before storage or publication, with a study code replacing the hospital number and the linking key held separately. Photographs of a child with clubbing, cyanosis or a syndromic appearance require separate written consent, and identifiable facial images should be avoided. For adolescents completing quality-of-life or psychosocial questionnaires, state who else sees the responses.

Clearance commonly takes six to ten weeks and retrospective approval is not granted.

7. Should echocardiographic measurements be reported raw, indexed to body surface area, or as Z-scores?

As Z-scores wherever a published nomogram exists, indexed to body surface area where it does not, and raw only alongside one of the other two — and this decision has to be made before data collection, because it determines what the proforma records. The reason is that every dimension on this page grows with the child, so a raw millimetre value is uninterpretable without knowing the child's size, and a study reporting mean left ventricular dimensions across an age range from infancy to adolescence has produced a number that describes nobody in the series. Three things must be stated explicitly in the methodology. The body surface area formula. Haycock, Mosteller and DuBois give measurably different values in small children, and since body surface area sits in the denominator, the indexed result and the Z-score both move with the formula chosen. Name it and use it consistently. The nomogram and its population. Most paediatric Z-score datasets in wide use derive from Western populations, and Indian children differ in body proportions, so a child may be classed as dilated or hypertrophic partly because of the reference. Name the source, and where none fits, say so in the limitations — that gap is precisely what the reference-value topics on this page exist to fill. What indexing does in a small or wasted child. This is the trap, and it affects the severe acute malnutrition, chronic anaemia, cyanotic growth-failure and heart-failure comparisons directly. Dividing a small heart by a small body surface area returns a value that can look normal or even elevated, so a child with genuinely reduced chamber dimensions indexes into the normal range and the study concludes that cardiac size is preserved. Much of the published disagreement about cardiac function in undernutrition comes from exactly this. Where the two groups differ systematically in body size — which is the whole point of those comparisons — report raw values and indexed values side by side, consider indexing to height rather than body surface area since height is less disturbed by acute weight loss, and state in the discussion which denominator the conclusion depends on. A finding that survives both denominators is worth reporting; a finding that reverses between them is a finding about arithmetic, and saying so honestly is what distinguishes a thesis that gets published from one that gets questioned.

8. Is a PhD research proposal different from an MD synopsis?

Substantially. A PhD proposal typically runs 6,000 to 10,000 words and carries an extended critical literature review, a theoretical framework, a detailed methodology chapter and a discussion of expected contribution to the field. An MD synopsis is a two to four page registration document. The research question can be the same; the depth expected is not.

9. When should the thesis topic be registered?

Most universities require registration within six to nine months of joining. Shortlist in the first two months, finalise with the guide by the third, and file for ethics clearance immediately afterwards. Recruitment here depends on someone else's list, which residents consistently underestimate: echocardiography slots are limited, the cardiologist may visit weekly, and a study needing additional measurements on each scan adds time to a list that is already full. Where school or community access is required, start that permission alongside the ethics submission. Close the data collection window at least six months before submission.

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