Liver Biopsy and Common Diffuse Liver Disease

1. Diagnostic spectrum of ultrasound-guided liver biopsies from adults with unexplained persistent liver enzyme elevation using routine histomorphology and special stains, correlated with clinical and biochemical diagnosis: a hospital-based cross-sectional study.
2. Adequacy of percutaneous liver biopsy specimens assessed by core length and complete portal tract count, correlated with ability to establish a definitive histopathological diagnosis: a retrospective laboratory audit.
3. Inter-observer agreement for assessing portal inflammation, interface activity, lobular inflammation and hepatocellular injury in adult liver biopsies using standardized semiquantitative criteria: an archival blinded agreement study.
4. Histopathological distribution of hepatitic, cholestatic, steatotic, granulomatous and vascular injury patterns in adult liver biopsies with abnormal liver function tests: a retrospective cross-sectional study.
5. Correlation of serum aminotransferase elevation with lobular inflammation, hepatocellular ballooning and necrosis in liver biopsies from adults with hepatitic biochemical profiles: an archival clinicopathological study.
6. Correlation of alkaline phosphatase and bilirubin concentrations with canalicular cholestasis, ductular reaction and portal oedema in liver biopsies from adults with cholestatic biochemical profiles: a retrospective study.
7. Diagnostic contribution of Masson trichrome staining for grading hepatic fibrosis against routine haematoxylin and eosin assessment in adult liver biopsies with chronic liver disease: a comparative cross-sectional study.
8. Diagnostic contribution of reticulin staining for assessing hepatic plate architecture in liver biopsies with suspected regenerative or neoplastic lesions, using integrated histopathological diagnosis as reference: an archival study.
9. Diagnostic utility of Perls Prussian blue staining for hepatic iron deposition in liver biopsies from adults with chronic liver disease, correlated with serum ferritin and transferrin saturation: a cross-sectional study.
10. Diagnostic utility of periodic acid-Schiff staining with diastase for hepatocellular cytoplasmic inclusions in biopsies with unexplained chronic liver disease, using final clinicopathological diagnosis as reference: an archival study.
11. Frequency and clinicopathological significance of ductular reaction in adult liver biopsies with chronic hepatitic and cholestatic disorders, correlated with fibrosis stage and serum alkaline phosphatase: a cross-sectional study.
12. Histological distribution of hepatocellular ballooning, apoptosis and spotty necrosis in adult liver biopsies with elevated aminotransferases, correlated with serum enzyme levels at biopsy: a retrospective cross-sectional study.
13. Correlation of portal inflammation severity with fibrosis stage in adult liver biopsies from chronic liver disease, using Masson trichrome staining as fibrosis assessment method: an archival clinicopathological study.
14. Histopathological spectrum of sinusoidal dilatation and congestion in adult liver biopsies, correlated with cardiac disease, portal hypertension and radiological vascular abnormalities: a retrospective cross-sectional study.
15. Inter-observer agreement for fibrosis staging in chronic liver disease using routine haematoxylin and eosin and Masson trichrome-stained liver biopsy sections: an archival blinded microscopy study.
16. Correlation of biopsy adequacy with concordance between histopathological diagnosis and final multidisciplinary diagnosis in adults undergoing liver biopsy for unexplained liver dysfunction: a retrospective study.
17. Histological patterns of cholestasis in adult liver biopsies using hepatocellular, canalicular and ductular parameters, correlated with biochemical and imaging evidence of obstruction: a cross-sectional study.
18. Histopathological spectrum of infiltrative liver disease in biopsies showing sinusoidal or portal infiltrates, using morphology and limited immunohistochemistry, with final integrated diagnosis as reference: an archival study.
19. Diagnostic yield of special stains in adult liver biopsies with initially indeterminate morphology, comparing routine histology alone with final diagnosis after targeted special staining: a retrospective diagnostic impact study.
20. Laboratory audit of liver biopsy reporting for adequacy, injury pattern, fibrosis stage, special-stain utilisation and clinicopathological correlation in a tertiary teaching hospital: a retrospective quality study.

Acute and Chronic Hepatitis

21. Histopathological spectrum of acute hepatitis in liver biopsies from adults with recent jaundice and aminotransferase elevation, correlated with viral serology and documented drug exposure: a retrospective cross-sectional study.
22. Correlation of lobular inflammation and hepatocellular necrosis with serum aminotransferase concentrations in adults with biopsy-confirmed acute hepatitis: a hospital-based clinicopathological cross-sectional study.
23. Histological features of acute hepatitis A in adults with positive serology, using lobular inflammation and cholestasis as parameters, correlated with bilirubin and aminotransferase levels: a retrospective study.
24. Histopathological spectrum of acute hepatitis E in adults with serologically confirmed infection, correlated with bilirubin, aminotransferases and coagulation parameters at diagnosis: a retrospective cross-sectional study.
25. Comparative histopathology of acute viral and drug-induced hepatitis using lobular inflammation, eosinophils, cholestasis and necrosis, with clinical aetiological diagnosis as reference: an archival comparative study.
26. Histological spectrum of chronic hepatitis B in liver biopsies from adults with persistent hepatitis B surface antigen positivity, correlated with viral load where routinely available and fibrosis stage: a retrospective study.
27. Correlation of interface hepatitis and portal inflammation with serum aminotransferases in adults with chronic hepatitis B undergoing clinically indicated liver biopsy: an archival clinicopathological study.
28. Histological staging of fibrosis in chronic hepatitis B using Masson trichrome staining, correlated with platelet count and serum albumin at biopsy: a retrospective cross-sectional study.
29. Histopathological spectrum of chronic hepatitis C in liver biopsies from serologically confirmed cases, using portal lymphoid aggregates and steatosis as parameters, correlated with fibrosis stage: an archival study.
30. Comparative histopathology of chronic hepatitis B and chronic hepatitis C using portal inflammation, interface activity, steatosis and fibrosis as parameters: a retrospective comparative cross-sectional study.
31. Inter-observer agreement for grading necroinflammatory activity in chronic viral hepatitis using standardized histological scoring criteria on archived liver biopsies: a blinded agreement study.
32. Inter-observer agreement for fibrosis staging in chronic viral hepatitis using Masson trichrome-stained liver biopsies and standardized staging criteria: an archival blinded study.
33. Correlation of platelet count with histological fibrosis stage in adults with chronic viral hepatitis undergoing liver biopsy: a retrospective clinicopathological study using fibrosis stage as reference.
34. Diagnostic performance of routinely available serum aminotransferase and platelet-based parameters for advanced fibrosis against liver biopsy fibrosis stage in chronic viral hepatitis: a retrospective diagnostic accuracy study.
35. Frequency of steatosis in chronic viral hepatitis and its correlation with fibrosis stage and metabolic risk factors at the time of biopsy: an archival cross-sectional study.
36. Histological characteristics of severe acute hepatitis with confluent or bridging necrosis, correlated with coagulation derangement and bilirubin at presentation: a retrospective cross-sectional liver biopsy study.
37. Morphological spectrum of submassive hepatic necrosis in liver tissue from acute liver failure, correlated with documented aetiology and biochemical severity at tissue sampling: an archival study.
38. Histopathological assessment of regenerative activity following severe acute hepatic injury using hepatocyte rosettes and ductular reaction, correlated with extent of parenchymal loss: an archival cross-sectional study.
39. Correlation of serum bilirubin with histological cholestasis severity in acute viral hepatitis using semiquantitative canalicular and hepatocellular cholestasis scoring: a retrospective study.
40. Clinicopathological audit of acute and chronic hepatitis biopsies assessing concordance among clinical aetiology, viral serology, histological pattern, activity grade and fibrosis stage: a retrospective study.

Steatotic Liver Disease

41. Histopathological spectrum of metabolic dysfunction-associated steatotic liver disease in adult liver biopsies using steatosis, ballooning, lobular inflammation and fibrosis, correlated with metabolic risk factors: a cross-sectional study.
42. Correlation of body mass index with percentage macrovesicular steatosis in adult liver biopsies from patients with metabolic dysfunction-associated steatotic liver disease: a retrospective clinicopathological study.
43. Association of diabetes mellitus with hepatocellular ballooning and fibrosis stage in adults with biopsy-proven metabolic dysfunction-associated steatotic liver disease: an archival cross-sectional study.
44. Association of dyslipidaemia with steatosis grade and lobular inflammation in adults with biopsy-proven metabolic dysfunction-associated steatotic liver disease: a retrospective study.
45. Correlation of serum alanine aminotransferase with steatosis, ballooning and lobular inflammation in adult liver biopsies with metabolic dysfunction-associated steatotic liver disease: a cross-sectional study.
46. Correlation of platelet count and serum albumin with fibrosis stage in adults with biopsy-proven metabolic dysfunction-associated steatotic liver disease: a retrospective clinicopathological study.
47. Inter-observer agreement for grading steatosis percentage in metabolic dysfunction-associated steatotic liver disease using routine haematoxylin and eosin-stained liver biopsies: an archival blinded study.
48. Inter-observer agreement for identifying hepatocellular ballooning in metabolic dysfunction-associated steatohepatitis using standardized morphological criteria: an archival blinded microscopy study.
49. Histological distribution of zone three perisinusoidal fibrosis in metabolic dysfunction-associated steatohepatitis, correlated with ballooning and lobular inflammation: an archival cross-sectional study.
50. Diagnostic contribution of Masson trichrome staining for perisinusoidal fibrosis in metabolic dysfunction-associated steatohepatitis compared with routine haematoxylin and eosin examination: a comparative study.
51. Frequency and morphological characteristics of Mallory-Denk bodies in steatohepatitis, correlated with ballooning severity and fibrosis stage: an archival cross-sectional liver biopsy study.
52. Comparative histopathology of simple steatosis and steatohepatitis using ballooning, lobular inflammation and pericellular fibrosis, with integrated histological diagnosis as reference: an archival study.
53. Comparative histopathology of metabolic dysfunction-associated and alcohol-related steatohepatitis using steatosis distribution, ballooning, neutrophils and fibrosis pattern: a retrospective cross-sectional study.
54. Histopathological spectrum of alcohol-related liver disease in liver biopsies and resections, including steatosis, steatohepatitis and cirrhosis, correlated with documented alcohol exposure: a retrospective study.
55. Correlation of documented alcohol exposure with steatosis grade, neutrophilic inflammation and pericellular fibrosis in adults with alcohol-related liver disease: an archival clinicopathological study.
56. Frequency and distribution of microvesicular steatosis in adult liver biopsies, correlated with documented metabolic, drug-related and acute systemic clinical conditions: a retrospective cross-sectional study.
57. Histological comparison of fibrosis distribution in metabolic dysfunction-associated steatohepatitis and chronic viral hepatitis using Masson trichrome staining: an archival comparative cross-sectional study.
58. Diagnostic performance of routine biochemical fibrosis indices calculated from available laboratory parameters against histological fibrosis stage in metabolic dysfunction-associated steatotic liver disease: a retrospective study.
59. Histopathological spectrum of steatotic liver changes in cholecystectomy patients undergoing clinically indicated liver sampling, correlated with obesity, diabetes and dyslipidaemia: a cross-sectional study.
60. Histopathology audit of liver biopsies with steatotic liver disease for steatosis percentage, ballooning, lobular inflammation, fibrosis stage and completeness of standardized reporting: a retrospective quality study.

Liver Fibrosis and Cirrhosis

61. Histological distribution of portal, periportal, bridging and perisinusoidal fibrosis in adult liver biopsies with chronic liver disease, correlated with documented aetiology: an archival cross-sectional study.
62. Correlation of serum albumin with histological fibrosis stage in adults with chronic liver disease undergoing biopsy: a retrospective clinicopathological study using Masson trichrome-based fibrosis assessment.
63. Correlation of platelet count with histological fibrosis stage in chronic liver disease using liver biopsy as reference standard: a retrospective diagnostic correlation study.
64. Diagnostic accuracy of platelet count for advanced hepatic fibrosis against Masson trichrome-based fibrosis staging in adult liver biopsies: a retrospective diagnostic accuracy study.
65. Correlation of ultrasonographic features of cirrhosis with histological architectural distortion and fibrosis stage in patients with paired imaging and liver tissue: a retrospective study.
66. Histopathological spectrum of cirrhosis in explant, resection and biopsy specimens, categorized by viral, alcohol-related, metabolic, autoimmune and cholestatic aetiologies: an archival cross-sectional study.
67. Comparative histomorphology of viral and metabolic cirrhosis using nodule size, septal fibrosis, steatosis and inflammatory activity: an archival comparative cross-sectional study.
68. Comparative histomorphology of alcohol-related and viral cirrhosis using steatosis, pericellular fibrosis, portal inflammation and regenerative nodules: an archival cross-sectional study.
69. Inter-observer agreement for fibrosis staging in chronic liver disease using standardized criteria on Masson trichrome-stained biopsy sections: an archival blinded microscopy study.
70. Inter-observer agreement for recognition of established cirrhosis in fragmented liver biopsies using architectural and fibrosis parameters: an archival blinded agreement study.
71. Diagnostic contribution of reticulin staining for evaluating regenerative nodularity in cirrhotic liver specimens compared with routine haematoxylin and eosin sections: an archival comparative study.
72. Histological characteristics of regenerative nodules in cirrhotic liver using reticulin architecture and cytological features, correlated with background fibrosis and aetiology: an archival cross-sectional study.
73. Frequency of low-grade and high-grade dysplastic nodules in cirrhotic liver resection specimens, using morphology and reticulin staining, correlated with coexisting hepatocellular carcinoma: an archival study.
74. Histological differentiation of regenerative and dysplastic nodules in cirrhotic liver using cell density, plate thickness and reticulin framework, with consensus diagnosis as reference: an archival study.
75. Correlation of splenomegaly and thrombocytopenia with histological cirrhosis and fibrosis stage in adults with chronic liver disease: a retrospective clinicopathological study.
76. Association of portal hypertension-related clinical findings with fibrosis stage and regenerative nodularity in liver tissue from chronic liver disease: a retrospective cross-sectional study.
77. Frequency and morphology of cholestasis in cirrhotic liver specimens and its association with bilirubin concentration and documented aetiology: an archival clinicopathological study.
78. Frequency of hepatocellular dysplasia in cirrhotic liver surrounding hepatocellular carcinoma, correlated with fibrosis pattern and underlying aetiology: an archival resection-specimen study.
79. Histopathological comparison of cirrhotic and non-cirrhotic background liver in hepatocellular carcinoma resections using fibrosis, steatosis and inflammatory activity parameters: an archival comparative study.
80. Histopathology reporting audit of chronic liver disease biopsies for aetiological pattern, inflammatory activity, fibrosis stage and relevant special-stain documentation: a retrospective laboratory quality study.

Cholestatic and Obstructive Liver Disease

81. Histopathological spectrum of cholestatic liver injury in adult liver biopsies using canalicular cholestasis, ductular reaction and portal oedema, correlated with bilirubin and alkaline phosphatase: a cross-sectional study.
82. Comparative histomorphology of intrahepatic and extrahepatic cholestasis using bile plugs, ductular proliferation and portal changes, with imaging-defined obstruction as comparator: a retrospective study.
83. Correlation of serum alkaline phosphatase with ductular reaction severity in liver biopsies from adults with cholestatic biochemical profiles: an archival clinicopathological cross-sectional study.
84. Correlation of serum bilirubin with histological canalicular cholestasis grade in adults undergoing liver biopsy for unexplained jaundice: a retrospective cross-sectional study.
85. Histological features of extrahepatic biliary obstruction in liver biopsies using portal oedema, ductular reaction and cholestasis, correlated with radiological level of obstruction: a retrospective study.
86. Diagnostic accuracy of ductular reaction and portal oedema for extrahepatic biliary obstruction against imaging and operative findings as reference standard: an archival diagnostic study.
87. Histopathological spectrum of primary biliary cholangitis in adult liver biopsies using bile duct injury, portal inflammation and ductopenia, correlated with available autoimmune serology: a retrospective study.
88. Correlation of florid duct lesions and ductopenia with fibrosis stage in biopsy-proven primary biliary cholangitis: an archival cross-sectional study using routine morphology and Masson trichrome staining.
89. Histopathological spectrum of primary sclerosing cholangitis using periductal fibrosis, duct loss and cholestasis, correlated with cholangiographic abnormalities where available: a retrospective study.
90. Diagnostic contribution of Masson trichrome staining for periductal fibrosis in suspected sclerosing cholangitis compared with routine haematoxylin and eosin examination: an archival comparative study.
91. Comparative histopathology of primary biliary cholangitis and primary sclerosing cholangitis using duct injury, portal inflammation and fibrosis distribution: an archival comparative cross-sectional study.
92. Histological spectrum of secondary sclerosing cholangitis in patients with documented biliary obstruction or recurrent cholangitis, correlated with imaging findings: a retrospective cross-sectional study.
93. Frequency and morphology of bile infarcts in severe cholestatic liver disease, correlated with serum bilirubin and radiological evidence of obstruction: an archival clinicopathological study.
94. Histological changes in prolonged biliary obstruction assessed by ductular proliferation, portal fibrosis and cholestasis, correlated with documented duration of obstruction: a retrospective study.
95. Inter-observer agreement for grading ductular reaction and duct loss in cholestatic liver disease using standardized morphological criteria: an archival blinded microscopy study.
96. Correlation of ductopenia severity with biochemical cholestasis in adult liver biopsies from chronic cholangiopathic disorders: a retrospective cross-sectional study.
97. Histopathological evaluation of cholestatic hepatitis associated with drug exposure using hepatocellular injury and canalicular cholestasis, compared with clinical causality assessment: a retrospective study.
98. Histological patterns of sepsis-associated cholestasis in liver tissue from patients with documented severe infection, correlated with bilirubin and alkaline phosphatase: an archival study.
99. Radiology-pathology correlation of biliary dilatation with histological obstructive changes in liver biopsies from patients with suspected extrahepatic obstruction: a retrospective study.
100. Laboratory audit of cholestatic liver biopsy reports for bile duct assessment, cholestasis pattern, ductular reaction, fibrosis and clinicoradiological correlation: a retrospective quality study.

Infectious and Granulomatous Liver Disease

101. Histopathological spectrum of granulomatous inflammation in adult liver biopsies, categorized by necrotising and non-necrotising patterns, correlated with microbiological and clinical diagnosis: a retrospective cross-sectional study.
102. Diagnostic utility of caseation, epithelioid granulomas and Langhans giant cells for hepatic tuberculosis against microbiological or clinicopathological confirmation as reference standard: an archival diagnostic study.
103. Diagnostic yield of Ziehl-Neelsen staining in liver biopsies with granulomatous inflammation suspicious for tuberculosis, using final clinicopathological diagnosis as reference: a retrospective diagnostic accuracy study.
104. Histopathological spectrum of hepatic tuberculosis in biopsy and resection specimens using granuloma morphology, necrosis and fibrosis, correlated with extrahepatic tuberculosis: an archival cross-sectional study.
105. Comparative histopathology of tuberculous and non-tuberculous hepatic granulomas using necrosis, inflammatory background and special-stain findings: an archival comparative diagnostic study.
106. Histopathological spectrum of pyogenic liver abscess wall specimens using necrosis, neutrophilic inflammation and granulation tissue, correlated with available microbiological culture findings: a retrospective study.
107. Diagnostic evaluation of amoebic liver abscess tissue using necrotic morphology and identification of trophozoites, compared with clinical and microbiological diagnosis: an archival study.
108. Histopathological spectrum of hydatid disease of the liver using laminated membrane, brood capsules and host tissue reaction, correlated with preoperative imaging: a retrospective study.
109. Diagnostic accuracy of histopathological examination for hydatid disease against operative and radiological diagnosis in resected hepatic cystic lesions: a retrospective diagnostic study.
110. Histopathological spectrum of fungal liver infections using routine morphology and periodic acid-Schiff staining, correlated with available microbiological confirmation and immune status: an archival study.
111. Diagnostic yield of periodic acid-Schiff staining in necrotising hepatic lesions suspicious for fungal infection, using final clinicopathological diagnosis as reference: an archival diagnostic study.
112. Histopathological characteristics of Candida-associated hepatic lesions using microabscesses and fungal forms, correlated with documented immunosuppression or haematological disease: a retrospective study.
113. Histological spectrum of parasitic hepatic lesions encountered in surgical pathology specimens, using morphology and special stains where indicated: an archival descriptive cross-sectional study.
114. Frequency and morphological characteristics of non-infectious granulomas in adult liver biopsies, correlated with documented drug exposure, autoimmune disease and systemic granulomatous disease: a retrospective study.
115. Histopathological spectrum of foreign-body granulomas in liver tissue using polarizable material and giant-cell response, correlated with prior surgery or intervention: an archival study.
116. Comparative diagnostic yield of routine morphology and targeted special stains in granulomatous liver disease, using final integrated clinicopathological diagnosis as reference: an archival study.
117. Correlation of granuloma distribution within portal, lobular and periportal compartments with final aetiological diagnosis in adult liver biopsies: a retrospective cross-sectional study.
118. Inter-observer agreement for classification of necrotising versus non-necrotising hepatic granulomas using routine histology: an archival blinded microscopy study.
119. Clinicopathological correlation of granulomatous liver disease using fever, liver enzyme profile, imaging findings and tissue morphology at diagnosis: a retrospective cross-sectional study.
120. Laboratory audit of liver biopsies with granulomatous inflammation for special-stain utilisation, microbiological correlation and final aetiological diagnosis: a retrospective quality study.

Drug- and Toxin-Induced Liver Injury

121. Histopathological spectrum of suspected drug-induced liver injury in adult liver biopsies using hepatitic, cholestatic, mixed and steatotic patterns, correlated with documented medication exposure: a retrospective study.
122. Comparative histopathology of hepatocellular and cholestatic drug-induced liver injury using necrosis, inflammation, eosinophils and cholestasis as index parameters: an archival cross-sectional study.
123. Correlation of biochemical hepatocellular injury pattern with lobular hepatitis and necrosis in biopsies from clinically suspected drug-induced liver injury: a retrospective clinicopathological study.
124. Correlation of biochemical cholestatic injury pattern with canalicular cholestasis and ductular reaction in biopsies from clinically suspected drug-induced liver injury: a retrospective study.
125. Histopathological spectrum of antitubercular drug-associated liver injury using hepatocellular necrosis, inflammation and cholestasis, correlated with documented treatment history: a retrospective cross-sectional study.
126. Histological characteristics of drug-associated granulomatous hepatitis using granuloma morphology and eosinophilic inflammation, correlated with documented medication exposure: an archival study.
127. Frequency and morphology of eosinophils in suspected drug-induced hepatitis, correlated with clinical drug causality assessment and final diagnosis: a retrospective cross-sectional study.
128. Histopathological spectrum of drug-associated steatohepatitis using steatosis, ballooning and pericellular fibrosis, correlated with documented drug exposure and metabolic factors: an archival study.
129. Histological patterns of chronic drug-induced liver injury using portal inflammation, fibrosis and duct injury, correlated with duration of medication exposure: a retrospective study.
130. Diagnostic differentiation of drug-induced hepatitis from autoimmune hepatitis using plasma cells, eosinophils and interface activity, with final clinical diagnosis as reference: an archival comparative study.
131. Diagnostic differentiation of drug-induced cholestasis from mechanical biliary obstruction using portal oedema, ductular reaction and imaging findings as reference: a retrospective study.
132. Histopathological spectrum of herbal and traditional medicine-associated liver injury in adults with documented exposure, using hepatitic and cholestatic injury patterns: a retrospective cross-sectional study.
133. Histological assessment of vascular-pattern drug injury using sinusoidal congestion and venular abnormalities, correlated with documented medication exposure: an archival observational study.
134. Inter-observer agreement for classifying drug-induced liver injury into hepatocellular, cholestatic and mixed histological patterns: an archival blinded microscopy study.
135. Correlation of serum bilirubin with histological cholestasis severity in clinically suspected drug-induced liver injury: a retrospective clinicopathological cross-sectional study.
136. Correlation of serum aminotransferases with hepatocellular necrosis severity in clinically suspected drug-induced liver injury: a retrospective cross-sectional study using semiquantitative histological scoring.
137. Frequency of bile duct injury and ductopenia in chronic drug-induced liver injury, correlated with cholestatic biochemical abnormalities: an archival cross-sectional study.
138. Comparative histopathology of drug-induced and acute viral hepatitis using lobular inflammation, portal inflammation, eosinophils and cholestasis: an archival comparative diagnostic study.
139. Diagnostic contribution of liver biopsy to clinically indeterminate suspected drug-induced liver injury, measured by change in final aetiological categorization after histopathological review: a retrospective study.
140. Histopathology audit of suspected drug-induced liver injury biopsies for injury-pattern description, fibrosis, eosinophils, cholestasis and documented clinicomedication correlation: a retrospective quality study.

Autoimmune and Immune-Mediated Liver Disease

141. Histopathological spectrum of autoimmune hepatitis in adult liver biopsies using interface hepatitis, plasma cells and lobular activity, correlated with available autoimmune serology: a retrospective cross-sectional study.
142. Correlation of plasma cell density with biochemical and serological features in biopsy-proven autoimmune hepatitis: an archival clinicopathological study using standardized semiquantitative inflammatory assessment.
143. Correlation of interface hepatitis severity with serum aminotransferases in adults with biopsy-proven autoimmune hepatitis: a retrospective cross-sectional clinicopathological study.
144. Correlation of fibrosis stage with serum albumin and platelet count in biopsy-proven autoimmune hepatitis: an archival cross-sectional study using Masson trichrome-based fibrosis staging.
145. Comparative histopathology of autoimmune hepatitis and chronic viral hepatitis using plasma cells, interface activity and lobular inflammation, with clinical diagnosis as reference: an archival study.
146. Comparative histopathology of autoimmune hepatitis and drug-induced hepatitis using interface activity, plasma cells, eosinophils and cholestasis: an archival diagnostic correlation study.
147. Inter-observer agreement for grading interface hepatitis in autoimmune hepatitis using standardized semiquantitative criteria: an archival blinded microscopy study.
148. Histological spectrum of primary biliary cholangitis using florid duct lesions, portal inflammation and ductopenia, correlated with available antimitochondrial antibody results: a retrospective study.
149. Correlation of bile duct loss with fibrosis stage and biochemical cholestasis in biopsy-proven primary biliary cholangitis: an archival cross-sectional study.
150. Histological spectrum of primary sclerosing cholangitis using periductal fibrosis, duct injury and ductopenia, correlated with cholangiography where available: a retrospective study.
151. Comparative histopathology of autoimmune hepatitis and primary biliary cholangitis using interface activity, plasma cells and bile duct injury: an archival comparative study.
152. Histopathological characteristics of autoimmune overlap-pattern liver disease using combined hepatitic and cholangiopathic features, correlated with available serology: a retrospective cross-sectional study.
153. Frequency of autoimmune overlap morphology among liver biopsies initially diagnosed as autoimmune hepatitis or primary biliary cholangitis: an archival review study using final integrated diagnosis.
154. Histopathological spectrum of immunoglobulin G4-related hepatobiliary disease using plasma cell-rich inflammation and fibrosis, correlated with available serum immunoglobulin G4 levels: an archival study.
155. Diagnostic contribution of immunoglobulin G4 immunohistochemistry in selected hepatobiliary biopsies with dense lymphoplasmacytic inflammation, using final integrated diagnosis as reference: an archival study.
156. Histological assessment of treatment-related changes in repeat autoimmune hepatitis biopsies using inflammatory activity and fibrosis, compared with pretreatment biopsy where available: a paired archival study.
157. Correlation of biochemical remission status with residual histological inflammation in clinically indicated follow-up biopsies from autoimmune hepatitis: a retrospective paired clinical-pathological study.
158. Inter-observer agreement for bile duct injury and ductopenia assessment in autoimmune cholangiopathies using standardized criteria: an archival blinded microscopy study.
159. Diagnostic performance of combined interface hepatitis and plasma cell-rich inflammation for autoimmune hepatitis against final multidisciplinary diagnosis as reference standard: a retrospective diagnostic study.
160. Laboratory audit of autoimmune liver disease biopsies for histological activity, fibrosis stage, bile duct injury and serological correlation: a retrospective quality study.

Metabolic and Storage Liver Disease

161. Histopathological spectrum of hepatic iron deposition in adult liver biopsies using Perls Prussian blue staining, correlated with serum ferritin and transferrin saturation: a retrospective cross-sectional study.
162. Semiquantitative grading of hepatocellular and reticuloendothelial iron deposition using Perls Prussian blue staining, correlated with underlying clinical diagnosis: an archival cross-sectional study.
163. Diagnostic differentiation of primary-pattern and secondary-pattern hepatic iron overload using distribution of Perls Prussian blue-positive iron, with clinical diagnosis as reference: an archival study.
164. Correlation of hepatic iron deposition grade with fibrosis stage in adults with iron overload undergoing liver biopsy: a retrospective clinicopathological study.
165. Histopathological spectrum of Wilson disease in liver biopsies using steatosis, hepatitic injury and fibrosis, correlated with available biochemical diagnostic findings: a retrospective study.
166. Diagnostic contribution of rhodanine staining for copper-associated protein in liver biopsies from clinically suspected Wilson disease, using final clinical diagnosis as reference: an archival study.
167. Comparative histopathology of Wilson disease and metabolic dysfunction-associated steatotic liver disease using steatosis, glycogenated nuclei and inflammatory features: an archival comparative study.
168. Histopathological characteristics of alpha-1 antitrypsin deficiency using periodic acid-Schiff-positive diastase-resistant globules, correlated with available clinical and biochemical diagnosis: an archival study.
169. Diagnostic yield of periodic acid-Schiff staining with diastase for alpha-1 antitrypsin-type inclusions in unexplained chronic liver disease: an archival diagnostic correlation study.
170. Histological spectrum of glycogen accumulation in paediatric and adult liver biopsies with suspected metabolic disease, correlated with final clinical diagnosis: an archival cross-sectional study.
171. Histopathological spectrum of storage-pattern liver disease using hepatocellular vacuolation and sinusoidal storage cells, correlated with established clinical diagnosis: an archival descriptive study.
172. Diagnostic contribution of routine morphology and targeted special stains in metabolic liver disease, using final clinicopathological diagnosis as reference standard: a retrospective study.
173. Frequency of unsuspected hepatic iron overload in liver biopsies performed for chronic liver disease of other documented aetiologies: an archival cross-sectional study.
174. Association of hepatic iron deposition with fibrosis severity in chronic viral and steatotic liver disease: an archival comparative cross-sectional study using Perls Prussian blue staining.
175. Frequency and distribution of glycogenated nuclei in metabolic dysfunction-associated steatotic liver disease, correlated with diabetes mellitus and fibrosis stage: an archival study.
176. Histopathological spectrum of secondary iron overload in patients with chronic transfusion exposure, correlated with documented transfusion burden and serum ferritin: a retrospective study.
177. Inter-observer agreement for semiquantitative hepatic iron grading using Perls Prussian blue-stained liver biopsy sections: an archival blinded microscopy study.
178. Inter-observer agreement for recognition of periodic acid-Schiff-positive diastase-resistant hepatocellular inclusions in suspected alpha-1 antitrypsin deficiency: an archival blinded study.
179. Clinicopathological correlation of inherited metabolic liver disease using age, biochemical abnormalities, histological injury pattern and fibrosis stage at biopsy: a retrospective cross-sectional study.
180. Laboratory audit of metabolic liver disease biopsies for appropriate utilisation and diagnostic yield of Perls Prussian blue, periodic acid-Schiff with diastase and rhodanine stains: a retrospective study.

Hepatic Vascular and Congestive Disorders

181. Histopathological spectrum of congestive hepatopathy in liver biopsies and resections using sinusoidal congestion, centrilobular atrophy and fibrosis, correlated with documented cardiac disease: a retrospective study.
182. Correlation of right-sided cardiac dysfunction with centrilobular congestion and fibrosis severity in liver tissue from patients with congestive hepatopathy: a retrospective clinicopathological study.
183. Histological characteristics of cardiac cirrhosis using central-to-central bridging fibrosis and sinusoidal congestion, correlated with duration of cardiac disease: an archival study.
184. Histopathological spectrum of Budd-Chiari syndrome using sinusoidal congestion, centrilobular necrosis and fibrosis, correlated with radiological hepatic venous obstruction: a retrospective study.
185. Diagnostic accuracy of centrilobular congestion and hepatocyte loss for hepatic venous outflow obstruction against radiological diagnosis as reference standard: an archival diagnostic study.
186. Comparative histopathology of congestive hepatopathy and Budd-Chiari syndrome using sinusoidal congestion, venous changes and fibrosis distribution: an archival comparative study.
187. Histopathological features of portal hypertension in non-cirrhotic liver biopsies using portal venopathy, sinusoidal dilatation and regenerative changes, correlated with clinical portal hypertension: a retrospective study.
188. Morphological spectrum of obliterative portal venopathy in liver biopsies from patients with non-cirrhotic portal hypertension, correlated with imaging and endoscopic findings: an archival study.
189. Histological evaluation of nodular regenerative hyperplasia using reticulin staining and preserved fibrosis pattern, correlated with portal hypertension: an archival diagnostic study.
190. Diagnostic contribution of reticulin staining for nodular regenerative hyperplasia compared with routine haematoxylin and eosin examination: an archival comparative diagnostic study.
191. Histopathological spectrum of portal vein thrombosis-associated liver changes using portal venous abnormalities and regenerative alterations, correlated with radiological thrombosis: a retrospective study.
192. Histological features of sinusoidal obstruction syndrome using sinusoidal congestion and central venular narrowing, correlated with documented treatment exposure: an archival clinicopathological study.
193. Comparative histopathology of sinusoidal obstruction syndrome and congestive hepatopathy using venular injury, congestion and fibrosis distribution: an archival diagnostic study.
194. Correlation of ascites and splenomegaly with portal vascular and sinusoidal abnormalities in non-cirrhotic portal hypertension liver biopsies: a retrospective cross-sectional study.
195. Inter-observer agreement for recognition of portal venopathy in liver biopsies using standardized portal vein morphological criteria: an archival blinded microscopy study.
196. Inter-observer agreement for grading sinusoidal dilatation and congestion in adult liver biopsies using standardized semiquantitative criteria: an archival blinded study.
197. Correlation of fibrosis distribution with clinical portal hypertension in patients with vascular liver disorders: an archival cross-sectional study using Masson trichrome-stained biopsies.
198. Histopathological changes in liver tissue from patients with chronic passive venous congestion, correlated with serum bilirubin and liver enzyme profile: a retrospective study.
199. Radiology-pathology correlation of hepatic venous and portal venous abnormalities with corresponding liver biopsy vascular patterns: a retrospective cross-sectional study.
200. Histopathology audit of vascular-pattern liver biopsies for sinusoidal changes, portal and central venous abnormalities, fibrosis distribution and radiological correlation: a retrospective quality study.

Hepatocellular Carcinoma

201. Histopathological spectrum of hepatocellular carcinoma in liver resection specimens classified according to current World Health Organization criteria, correlated with tumour size and pathological stage: an archival cross-sectional study.
202. Correlation of histological differentiation with tumour size, vascular invasion and satellite nodules in hepatocellular carcinoma resection specimens: a retrospective clinicopathological study.
203. Histological distribution of trabecular, pseudoglandular and solid growth patterns in hepatocellular carcinoma, correlated with tumour differentiation and vascular invasion: an archival cross-sectional study.
204. Frequency and pathological characteristics of steatohepatitic hepatocellular carcinoma, correlated with metabolic risk factors and background steatotic liver disease: an archival clinicopathological study.
205. Histomorphological characteristics of clear-cell hepatocellular carcinoma using percentage clear-cell component and tumour differentiation, correlated with background liver disease: an archival cross-sectional study.
206. Histological features of scirrhous hepatocellular carcinoma using stromal proportion and growth pattern, compared with conventional hepatocellular carcinoma: an archival comparative study.
207. Frequency and clinicopathological associations of macrotrabecular growth in hepatocellular carcinoma, correlated with tumour size, vascular invasion and pathological stage: an archival study.
208. Association of microscopic vascular invasion with tumour size, differentiation, capsule status and satellite nodules in hepatocellular carcinoma: an archival prognostic pathology study.
209. Correlation of tumour capsule invasion with microscopic vascular invasion and satellite nodules in resected hepatocellular carcinoma: a retrospective cross-sectional study.
210. Frequency and distribution of satellite nodules in hepatocellular carcinoma resections, correlated with primary tumour size and vascular invasion: an archival clinicopathological study.
211. Correlation of tumour necrosis percentage with histological differentiation and tumour size in untreated hepatocellular carcinoma resection specimens: an archival cross-sectional study.
212. Histopathological spectrum of background liver in hepatocellular carcinoma resections, including cirrhosis, chronic hepatitis and steatohepatitis: an archival cross-sectional study.
213. Association of background cirrhosis with tumour multiplicity, size and differentiation in hepatocellular carcinoma resection specimens: a retrospective clinicopathological study.
214. Diagnostic utility of arginase-1 immunohistochemistry for hepatocellular differentiation in primary hepatic malignancies, using final integrated diagnosis as reference standard: an archival diagnostic accuracy study.
215. Diagnostic performance of hepatocyte paraffin 1 and arginase-1 for hepatocellular carcinoma against cholangiocarcinoma and metastatic adenocarcinoma: an archival comparative diagnostic study.
216. Diagnostic utility of glypican-3 immunohistochemistry for hepatocellular carcinoma in morphologically difficult liver tumours, using final integrated histopathological diagnosis as reference: an archival study.
217. Comparative expression of arginase-1, hepatocyte paraffin 1 and glypican-3 in well, moderately and poorly differentiated hepatocellular carcinoma: an archival cross-sectional immunohistochemical study.
218. Correlation of serum alpha-fetoprotein with tumour size, differentiation and vascular invasion in histologically confirmed hepatocellular carcinoma: a retrospective clinicopathological study.
219. Inter-observer agreement for grading hepatocellular carcinoma differentiation using standardized morphological criteria on resection specimens: an archival blinded microscopy study.
220. Histopathology audit of hepatocellular carcinoma resections for tumour size, multiplicity, differentiation, vascular invasion, satellite nodules, margins and background liver pathology: a retrospective quality study.

Intrahepatic Cholangiocarcinoma

221. Histopathological spectrum of intrahepatic cholangiocarcinoma in liver resection specimens using glandular architecture, stromal reaction and tumour differentiation, correlated with pathological stage: an archival cross-sectional study.
222. Histological comparison of small-duct and large-duct patterns of intrahepatic cholangiocarcinoma using tumour architecture, mucin production and stromal characteristics: an archival comparative study.
223. Correlation of tumour differentiation with lymphovascular invasion, perineural invasion and pathological stage in intrahepatic cholangiocarcinoma resections: a retrospective clinicopathological study.
224. Association of desmoplastic stromal reaction with tumour differentiation and invasive characteristics in intrahepatic cholangiocarcinoma: an archival cross-sectional study using semiquantitative stromal assessment.
225. Frequency and pathological significance of perineural invasion in intrahepatic cholangiocarcinoma, correlated with tumour size, differentiation and margin status: an archival study.
226. Frequency and pathological significance of lymphovascular invasion in intrahepatic cholangiocarcinoma, correlated with tumour size and pathological stage: a retrospective cross-sectional study.
227. Histological spectrum of precursor biliary epithelial changes adjacent to intrahepatic cholangiocarcinoma, correlated with tumour morphology and background biliary disease: an archival study.
228. Diagnostic performance of cytokeratin 7 and cytokeratin 19 for supporting biliary differentiation in primary liver adenocarcinoma, using final integrated diagnosis as reference: an archival study.
229. Diagnostic differentiation of intrahepatic cholangiocarcinoma from hepatocellular carcinoma using arginase-1, hepatocyte paraffin 1, cytokeratin 7 and cytokeratin 19: an archival diagnostic study.
230. Diagnostic differentiation of intrahepatic cholangiocarcinoma from metastatic colorectal adenocarcinoma using cytokeratin 7, cytokeratin 20, caudal type homeobox 2 and special AT-rich sequence-binding protein 2: an archival study.
231. Correlation of serum carbohydrate antigen 19-9 with tumour size, differentiation and stage in histologically confirmed intrahepatic cholangiocarcinoma: a retrospective clinicopathological study.
232. Histopathological characteristics of multifocal intrahepatic cholangiocarcinoma compared with solitary tumours using grade, vascular invasion and background liver changes: an archival comparative study.
233. Frequency and morphology of tumour necrosis in intrahepatic cholangiocarcinoma, correlated with tumour size and histological differentiation: an archival cross-sectional study.
234. Histological evaluation of surgical margins in intrahepatic cholangiocarcinoma resections and association with tumour size, perineural invasion and vascular invasion: a retrospective study.
235. Histopathological characteristics of regional lymph-node metastases from intrahepatic cholangiocarcinoma, correlated with primary tumour differentiation and lymphovascular invasion: an archival paired-specimen study.
236. Comparative histopathology of hepatocellular carcinoma and intrahepatic cholangiocarcinoma in poorly differentiated liver tumours using morphology and limited immunohistochemistry: an archival diagnostic study.
237. Inter-observer agreement for histological grading of intrahepatic cholangiocarcinoma using standardized differentiation criteria: an archival blinded microscopy study.
238. Inter-observer agreement for identifying perineural and lymphovascular invasion in intrahepatic cholangiocarcinoma resection specimens: an archival blinded agreement study.
239. Correlation of radiological tumour size and multifocality with histopathological tumour dimensions and multiplicity in intrahepatic cholangiocarcinoma resections: a retrospective radiology-pathology study.
240. Histopathology audit of intrahepatic cholangiocarcinoma resections for subtype, differentiation, vascular invasion, perineural invasion, margins, nodes and pathological staging completeness: a retrospective quality study.

Metastatic Tumours of Liver

241. Histopathological spectrum of metastatic malignancies in liver biopsies, categorized by primary site and morphology, correlated with documented clinical and radiological primary tumour diagnosis: an archival cross-sectional study.
242. Diagnostic differentiation of metastatic adenocarcinoma from hepatocellular carcinoma using morphology, arginase-1 and epithelial immunohistochemical markers, with final integrated diagnosis as reference: an archival study.
243. Histopathological characteristics of colorectal carcinoma metastases to liver using gland formation, dirty necrosis and stromal reaction, correlated with known colorectal primary: an archival study.
244. Diagnostic utility of special AT-rich sequence-binding protein 2 and caudal type homeobox 2 for colorectal origin in metastatic liver adenocarcinoma, using final clinical diagnosis as reference: an archival study.
245. Diagnostic performance of cytokeratin 7 and cytokeratin 20 expression patterns for directing primary-site evaluation in metastatic liver adenocarcinoma: an archival diagnostic correlation study.
246. Histopathological spectrum of pancreaticobiliary adenocarcinoma metastases to liver using glandular morphology and cytokeratin 7 expression, correlated with documented primary site: an archival study.
247. Histomorphological and immunohistochemical characteristics of breast carcinoma metastatic to liver using GATA binding protein 3 and documented breast primary as reference: an archival study.
248. Diagnostic evaluation of lung adenocarcinoma metastatic to liver using thyroid transcription factor 1 immunohistochemistry, correlated with documented pulmonary primary tumour: an archival diagnostic study.
249. Histopathological spectrum of neuroendocrine tumour metastases in liver using architecture and neuroendocrine immunohistochemistry, correlated with documented primary site: an archival cross-sectional study.
250. Correlation of Ki-67 proliferation index with histological grade in metastatic well-differentiated neuroendocrine tumours of liver: an archival cross-sectional immunohistochemical study.
251. Diagnostic utility of synaptophysin and chromogranin immunohistochemistry for neuroendocrine differentiation in metastatic liver tumours, using final integrated diagnosis as reference: an archival study.
252. Histopathological spectrum of metastatic squamous cell carcinoma in liver biopsies using morphology and organ-directed immunohistochemistry, correlated with documented primary tumour: an archival study.
253. Diagnostic work-up of metastatic liver carcinoma of unknown primary using morphology and a limited immunohistochemical panel, measured by proportion assigned a probable primary site: a retrospective study.
254. Correlation of radiological multiplicity and distribution of liver lesions with histopathological diagnosis of metastatic versus primary hepatic malignancy: a retrospective radiology-pathology study.
255. Comparative morphology of solitary and multiple liver metastases using primary-site distribution, tumour differentiation and necrosis as parameters: an archival cross-sectional study.
256. Histological assessment of treatment-related necrosis and fibrosis in resected liver metastases after documented systemic therapy, correlated with viable tumour percentage: a retrospective study.
257. Diagnostic concordance between liver core biopsy and subsequent hepatic resection for metastatic tumour type and differentiation: a retrospective paired-specimen study.
258. Inter-observer agreement for estimating viable tumour percentage in treated hepatic metastases using routine histology: an archival blinded microscopy study.
259. Correlation of serum carcinoembryonic antigen with metastatic tumour burden and histological diagnosis in patients with colorectal carcinoma metastatic to liver: a retrospective clinicopathological study.
260. Histopathology audit of liver biopsy work-up for metastatic malignancy, assessing clinical history, immunohistochemistry panel size, primary-site assignment and diagnostic concordance: a retrospective quality study.

Benign Hepatocellular Lesions and Nodular Liver Lesions

261. Histopathological spectrum of benign hepatocellular nodular lesions in liver resections using architecture, cytology and reticulin framework, correlated with preoperative imaging diagnosis: an archival cross-sectional study.
262. Histological characteristics of focal nodular hyperplasia using central scar, ductular reaction and map-like architecture, correlated with radiological diagnosis: an archival radiology-pathology correlation study.
263. Diagnostic contribution of reticulin staining in focal nodular hyperplasia compared with routine haematoxylin and eosin sections, using final integrated diagnosis as reference: an archival study.
264. Histopathological spectrum of hepatocellular adenoma using steatosis, inflammation, sinusoidal dilatation and cytological atypia, correlated with age and documented hormonal exposure: an archival study.
265. Morphology-based subclassification of hepatocellular adenoma using routine histology and available limited immunohistochemistry, with final integrated diagnosis as reference: an archival cross-sectional study.
266. Histological differentiation of focal nodular hyperplasia from hepatocellular adenoma using ductular reaction, fibrous septa and reticulin architecture: an archival comparative diagnostic study.
267. Histological differentiation of hepatocellular adenoma from well-differentiated hepatocellular carcinoma using reticulin framework, cytological atypia and stromal invasion: an archival diagnostic study.
268. Frequency and morphological features of regenerative nodules in cirrhotic liver resections, using reticulin staining and background fibrosis as assessment parameters: an archival cross-sectional study.
269. Histological differentiation of regenerative nodules from low-grade dysplastic nodules using cell density, cytological atypia and reticulin architecture: an archival blinded diagnostic study.
270. Histological differentiation of low-grade from high-grade dysplastic nodules in cirrhotic liver using small-cell change, architectural atypia and reticulin framework: an archival comparative study.
271. Frequency of high-grade dysplastic nodules adjacent to hepatocellular carcinoma in cirrhotic liver resections, correlated with tumour multiplicity and background liver disease: an archival study.
272. Inter-observer agreement for classification of regenerative, low-grade dysplastic and high-grade dysplastic nodules in cirrhotic liver using standardized morphological criteria: an archival blinded study.
273. Histopathological spectrum of incidental benign hepatic nodules identified in liver resection specimens performed for other lesions: an archival cross-sectional study with radiological correlation.
274. Correlation of radiological enhancement pattern with histological diagnosis in resected benign hepatocellular lesions: a retrospective radiology-pathology cross-sectional study.
275. Diagnostic utility of glutamine synthetase immunohistochemistry in selected hepatocellular nodular lesions, using final integrated histopathological diagnosis as reference: an archival study.
276. Comparative reticulin architecture in focal nodular hyperplasia, hepatocellular adenoma and well-differentiated hepatocellular carcinoma: an archival comparative histopathological study.
277. Frequency and morphology of fatty change in benign hepatocellular nodules, correlated with background metabolic dysfunction-associated steatotic liver disease: an archival cross-sectional study.
278. Histopathological characteristics of haemorrhage and necrosis in hepatocellular adenoma, correlated with tumour size and documented hormonal exposure: an archival study.
279. Diagnostic concordance between core biopsy and resection diagnosis in benign and indeterminate hepatocellular nodular lesions: a retrospective paired-specimen study.
280. Histopathology audit of benign hepatocellular lesion resections for gross sampling, reticulin staining, diagnostic categorization and radiology-pathology concordance: a retrospective quality study.

Liver Cytology and Core Biopsy of Focal Lesions

281. Diagnostic accuracy of fine needle aspiration cytology for focal liver lesions against core biopsy or resection histopathology as reference standard: a hospital-based retrospective cross-sectional study.
282. Diagnostic accuracy of image-guided liver core biopsy for malignant focal liver lesions against subsequent resection or integrated clinicopathological diagnosis as reference standard: a retrospective study.
283. Comparative diagnostic yield of fine needle aspiration cytology and core biopsy in paired focal liver lesion samples, using final integrated diagnosis as reference: a retrospective comparative study.
284. Cytomorphological features of hepatocellular carcinoma in fine needle aspiration specimens, correlated with histological differentiation in paired core biopsy or resection specimens: an archival study.
285. Diagnostic accuracy of cytological trabecular architecture and endothelial wrapping for hepatocellular carcinoma against histopathological diagnosis as reference standard: an archival diagnostic study.
286. Cytomorphological differentiation of hepatocellular carcinoma from metastatic adenocarcinoma in liver aspirates, using histopathology and immunohistochemistry as reference: a retrospective diagnostic study.
287. Cytological spectrum of metastatic adenocarcinoma in focal liver lesions, correlated with core biopsy histopathology and documented primary tumour site: an archival cross-sectional study.
288. Diagnostic utility of cell block preparation as an adjunct to liver fine needle aspiration cytology for malignant focal lesions, using histopathology as reference standard: a retrospective study.
289. Diagnostic contribution of arginase-1 immunocytochemistry on liver aspirate cell blocks in suspected hepatocellular carcinoma, using histopathology as reference: an archival diagnostic study.
290. Diagnostic contribution of cytokeratin 7 and cytokeratin 19 immunocytochemistry on liver lesion cell blocks in suspected cholangiocarcinoma, using histopathology as reference: an archival study.
291. Diagnostic accuracy of fine needle aspiration cytology for liver metastases against core biopsy histopathology as reference standard: a retrospective diagnostic accuracy study.
292. Cytological spectrum of neuroendocrine tumour metastases to liver and correlation with histopathology and Ki-67 proliferation index: an archival cytohistological study.
293. Diagnostic evaluation of liver abscess aspiration cytology using necrotic background and inflammatory cellularity, correlated with microbiological culture and clinical diagnosis: a retrospective study.
294. Cytological identification of granulomatous inflammation in liver aspirates, correlated with core biopsy histopathology and microbiological investigations: a retrospective diagnostic correlation study.
295. Analysis of false-negative cytology in histologically confirmed malignant focal liver lesions, assessing cellularity, necrosis and sampling characteristics: a retrospective laboratory discrepancy audit.
296. Analysis of false-positive cytology diagnoses in focal liver lesions using paired histopathology and retrospective slide review: a laboratory diagnostic discrepancy study.
297. Inter-observer agreement for cytological distinction between primary hepatocellular malignancy and metastatic carcinoma in liver aspirates using standardized criteria: an archival blinded study.
298. Adequacy of image-guided liver core biopsies for tumour typing and immunohistochemistry assessed by core length and viable tumour percentage: a retrospective laboratory audit.
299. Diagnostic concordance of liver core biopsy with subsequent resection for primary and metastatic hepatic malignancies: a retrospective paired-specimen agreement study.
300. Cytopathology and core-biopsy service audit for focal liver lesions assessing adequacy, diagnostic yield, ancillary testing, turnaround time and histological concordance: a retrospective quality study.

Non-Neoplastic Gallbladder Pathology

301. Histopathological spectrum of non-neoplastic gallbladder lesions in routine cholecystectomy specimens, correlated with age, sex, gallstones and preoperative diagnosis: a hospital-based retrospective cross-sectional study.
302. Histological spectrum of chronic cholecystitis in cholecystectomy specimens using mucosal injury, fibrosis and muscular hypertrophy, correlated with gallstone status: an archival cross-sectional study.
303. Correlation of chronic cholecystitis severity with duration of symptoms and gallbladder wall thickness on ultrasonography: a retrospective radiology-pathology correlation study.
304. Histopathological characteristics of acute cholecystitis using neutrophilic inflammation, mucosal ulceration and mural oedema, correlated with clinical and radiological diagnosis: a retrospective study.
305. Diagnostic concordance between clinical acute cholecystitis and histopathological acute inflammation in cholecystectomy specimens: a retrospective cross-sectional agreement study.
306. Histopathological spectrum of xanthogranulomatous cholecystitis using foamy histiocytes, fibrosis and inflammatory infiltrates, correlated with imaging findings suspicious for malignancy: a retrospective study.
307. Diagnostic differentiation of xanthogranulomatous cholecystitis from gallbladder carcinoma using morphology and limited immunohistochemistry where required, with final resection diagnosis as reference: an archival study.
308. Frequency and clinicopathological characteristics of follicular cholecystitis in routine cholecystectomy specimens, correlated with gallstones and chronic inflammatory changes: an archival cross-sectional study.
309. Histopathological characteristics of eosinophilic cholecystitis using eosinophil density and mural distribution, correlated with peripheral eosinophilia where available: a retrospective study.
310. Morphological features of gangrenous cholecystitis using transmural necrosis and vascular thrombosis, correlated with diabetes mellitus and clinical severity: a retrospective cross-sectional study.
311. Frequency and morphological spectrum of cholesterolosis in routine cholecystectomy specimens, correlated with gallstone status and serum lipid profile where available: an archival study.
312. Histopathological characteristics of adenomyomatosis using Rokitansky-Aschoff sinuses and muscular hypertrophy, correlated with ultrasonographic wall thickening: a retrospective radiology-pathology study.
313. Diagnostic concordance between ultrasonographic diagnosis of adenomyomatosis and final cholecystectomy histopathology: a retrospective diagnostic accuracy study.
314. Frequency of pyloric and intestinal metaplasia in chronic cholecystitis, correlated with age, gallstones and mucosal inflammation: an archival cross-sectional study.
315. Association of mucosal metaplasia with dysplasia in routine cholecystectomy specimens using systematic histological review: an archival cross-sectional study.
316. Frequency of unexpected dysplasia in cholecystectomy specimens clinically diagnosed as benign gallstone disease: a retrospective cross-sectional study.
317. Frequency of incidental gallbladder carcinoma in routine cholecystectomy specimens performed for presumed benign disease: a retrospective hospital-based cross-sectional study.
318. Correlation of gross gallbladder wall thickening with chronic inflammation, xanthogranulomatous cholecystitis and carcinoma on histopathology: a retrospective gross-pathology correlation study.
319. Inter-observer agreement for grading chronic inflammatory and mucosal metaplastic changes in gallbladder specimens using standardized morphological criteria: an archival blinded study.
320. Histopathology audit of routine cholecystectomy specimens for representative sampling, mucosal abnormalities, dysplasia, incidental carcinoma and final diagnostic completeness: a retrospective quality study.

Gallstone-Associated Gallbladder Pathology

321. Histopathological spectrum of gallbladder mucosal changes associated with cholelithiasis, including inflammation, metaplasia, dysplasia and carcinoma: a hospital-based retrospective cross-sectional study.
322. Comparative histopathology of gallbladders with and without calculi using chronic inflammation, fibrosis, mucosal metaplasia and dysplasia as index parameters: an archival comparative study.
323. Correlation of gallstone number with severity of chronic cholecystitis and mucosal metaplasia in routine cholecystectomy specimens: a retrospective cross-sectional study.
324. Correlation of gallstone size with gallbladder wall thickness, mucosal ulceration and chronic inflammation in cholecystectomy specimens: an archival clinicopathological study.
325. Association of longstanding gallstone symptoms with pyloric and intestinal metaplasia in cholecystectomy specimens: a retrospective clinicopathological cross-sectional study.
326. Frequency of epithelial dysplasia in gallbladders with cholelithiasis and its association with intestinal metaplasia: an archival cross-sectional study using systematic mucosal examination.
327. Frequency of incidental carcinoma among cholecystectomy specimens with cholelithiasis, correlated with patient age, wall thickening and mucosal abnormalities: a retrospective study.
328. Histopathological comparison of cholesterol and pigment stone-associated gallbladder lesions where stone type is documented, using inflammation and metaplastic changes: a retrospective study.
329. Association of gallbladder wall thickness on ultrasonography with chronic inflammation and fibrosis in patients with cholelithiasis: a retrospective radiology-pathology correlation study.
330. Correlation of gallbladder wall thickness with xanthogranulomatous inflammation in cholecystectomy specimens from patients with gallstones: a retrospective cross-sectional study.
331. Histopathological spectrum of gallbladder neck obstruction associated with impacted calculi, using mucosal injury, fibrosis and muscular hypertrophy as parameters: an archival study.
332. Frequency and morphology of Rokitansky-Aschoff sinuses in gallstone-associated chronic cholecystitis, correlated with muscular hypertrophy and wall thickness: an archival cross-sectional study.
333. Association of mucosal ulceration with acute-on-chronic cholecystitis in gallstone-bearing gallbladders: a retrospective histopathological cross-sectional study.
334. Histological spectrum of gangrenous change in gallstone-associated acute cholecystitis, correlated with diabetes mellitus and inflammatory laboratory parameters: a retrospective study.
335. Frequency of cholesterolosis in gallstone-bearing versus non-gallstone gallbladders using histopathology as reference: an archival comparative cross-sectional study.
336. Histopathological progression from chronic inflammation through metaplasia and dysplasia in gallstone-bearing gallbladders using systematic mucosal mapping: an archival cross-sectional study.
337. Association of age with prevalence of metaplasia, dysplasia and incidental carcinoma in cholecystectomy specimens containing gallstones: a retrospective cross-sectional study.
338. Correlation of ultrasonographic polypoid or focal wall lesions in gallstone-bearing gallbladders with cholesterolosis, adenomyomatosis, dysplasia and neoplasia on histopathology: a retrospective study.
339. Histopathological yield of additional sections from grossly abnormal gallbladder mucosa in cholelithiasis, measured by detection of metaplasia, dysplasia and incidental carcinoma: a retrospective audit.
340. Laboratory audit of gallstone-associated cholecystectomy specimens for clinical information, gross sampling, metaplasia, dysplasia and incidental malignancy detection: a retrospective quality study.

Premalignant Gallbladder Lesions

341. Frequency and distribution of pyloric metaplasia in routine cholecystectomy specimens, correlated with chronic cholecystitis severity and gallstone status: an archival cross-sectional study.
342. Frequency and distribution of intestinal metaplasia in gallbladder mucosa, correlated with age, gallstone status and chronic inflammatory changes: an archival cross-sectional study.
343. Comparative histomorphology of pyloric and intestinal metaplasia in cholecystectomy specimens using epithelial phenotype and associated inflammation: an archival comparative study.
344. Association of intestinal metaplasia with low-grade and high-grade gallbladder dysplasia using systematic review of routine cholecystectomy specimens: an archival cross-sectional study.
345. Histopathological spectrum of gallbladder dysplasia using architectural complexity and cytological atypia, correlated with adjacent metaplasia and invasive carcinoma: an archival study.
346. Inter-observer agreement for distinguishing reactive atypia from low-grade gallbladder dysplasia using standardized morphological criteria: an archival blinded microscopy study.
347. Inter-observer agreement for distinguishing low-grade from high-grade gallbladder dysplasia using standardized architectural and cytological criteria: an archival blinded study.
348. Frequency of low-grade dysplasia in routine cholecystectomy specimens and its association with age, gallstones and mucosal metaplasia: a retrospective cross-sectional study.
349. Frequency of high-grade dysplasia in cholecystectomy specimens and its association with occult invasive gallbladder carcinoma: an archival cross-sectional study.
350. Histological mapping of dysplasia adjacent to invasive gallbladder adenocarcinoma, assessing distance, grade and associated metaplastic changes: an archival resection-specimen study.
351. Correlation of p53 expression pattern with severity of gallbladder epithelial dysplasia using consensus morphology as reference: an archival immunohistochemical cross-sectional study.
352. Correlation of Ki-67 proliferative activity with reactive epithelium, metaplasia, low-grade dysplasia and high-grade dysplasia in gallbladder mucosa: an archival study.
353. Comparative p53 and Ki-67 expression across chronic cholecystitis, metaplasia, dysplasia and gallbladder adenocarcinoma: an archival cross-sectional immunohistochemical study.
354. Histopathological spectrum of intracholecystic papillary-tubular neoplasm using growth pattern, epithelial phenotype and associated invasive carcinoma: an archival descriptive study.
355. Diagnostic differentiation of intracholecystic papillary-tubular neoplasm from reactive polypoid mucosal lesions using architecture and cytological atypia: an archival comparative diagnostic study.
356. Frequency of invasive carcinoma associated with intracholecystic papillary-tubular neoplasm in resected gallbladder specimens: an archival cross-sectional study using systematic sampling.
357. Correlation of gross polypoid gallbladder lesions with histological adenoma, intracholecystic papillary-tubular neoplasm, cholesterol polyp and carcinoma: a retrospective gross-pathology correlation study.
358. Diagnostic yield of extensive sampling in gallbladders with high-grade dysplasia for detection of occult invasive carcinoma: a retrospective laboratory audit.
359. Association of gallstone disease with metaplasia-dysplasia-carcinoma sequence changes in gallbladder mucosa: an archival cross-sectional histopathological study.
360. Histopathology audit of premalignant gallbladder lesions for grading, associated metaplasia, additional sampling and exclusion of invasive carcinoma: a retrospective quality study.

Gallbladder Carcinoma

361. Histopathological spectrum of gallbladder carcinoma in cholecystectomy and radical cholecystectomy specimens classified by current World Health Organization criteria: an archival cross-sectional study with stage correlation.
362. Correlation of histological differentiation with depth of invasion, lymphovascular invasion and nodal metastasis in gallbladder adenocarcinoma: a retrospective clinicopathological study.
363. Histological characteristics of conventional gallbladder adenocarcinoma using gland formation, desmoplasia and invasion pattern, correlated with pathological stage: an archival cross-sectional study.
364. Histopathological features of papillary gallbladder adenocarcinoma using exophytic architecture and invasion depth, compared with conventional adenocarcinoma: an archival comparative study.
365. Histopathological spectrum of mucinous and signet-ring cell gallbladder carcinoma using mucin distribution and tumour differentiation, correlated with pathological stage: an archival study.
366. Histological characteristics of adenosquamous and squamous gallbladder carcinoma using component proportions and invasion, correlated with tumour stage: an archival cross-sectional study.
367. Morphological and immunohistochemical characterization of gallbladder neuroendocrine carcinoma using neuroendocrine markers and Ki-67, compared with final integrated diagnosis: an archival study.
368. Frequency and clinicopathological characteristics of uncommon histological variants of gallbladder carcinoma in resection specimens: an archival descriptive cross-sectional study.
369. Association of depth of gallbladder wall invasion with lymphovascular invasion and nodal metastasis in gallbladder carcinoma: an archival prognostic pathology study.
370. Correlation of direct liver invasion with tumour size, depth of gallbladder wall invasion and nodal metastasis in radical cholecystectomy specimens: a retrospective study.
371. Frequency and pathological significance of lymphovascular invasion in gallbladder carcinoma, correlated with tumour differentiation, depth of invasion and nodal status: an archival study.
372. Frequency and pathological significance of perineural invasion in gallbladder carcinoma, correlated with tumour differentiation, depth of invasion and margin status: an archival study.
373. Association of cystic duct margin involvement with tumour location, depth of invasion and nodal metastasis in gallbladder carcinoma: a retrospective radical cholecystectomy study.
374. Histopathological evaluation of regional lymph nodes in gallbladder carcinoma and correlation of nodal metastasis with primary tumour differentiation and invasion: an archival paired-specimen study.
375. Frequency and morphological characteristics of incidental gallbladder carcinoma detected in cholecystectomy specimens performed for presumed benign disease: a retrospective cross-sectional study.
376. Histopathological comparison of incidental and clinically suspected gallbladder carcinoma using tumour size, differentiation, depth of invasion and stage: an archival comparative study.
377. Correlation of ultrasonographic or computed tomographic wall thickening with tumour depth and liver invasion in gallbladder carcinoma: a retrospective radiology-pathology correlation study.
378. Correlation of serum carbohydrate antigen 19-9 with tumour stage and nodal status in histologically confirmed gallbladder carcinoma: a retrospective clinicopathological study.
379. Inter-observer agreement for assessing depth of invasion and perineural invasion in gallbladder carcinoma resection specimens using standardized criteria: an archival blinded study.
380. Histopathology audit of gallbladder carcinoma resections for tumour type, differentiation, depth, liver invasion, vascular invasion, perineural invasion, margins and nodal staging: a retrospective quality study.

Extrahepatic Bile Duct Pathology and Cholangiocarcinoma

381. Histopathological spectrum of extrahepatic bile duct lesions in resection specimens, including inflammatory strictures, dysplasia and carcinoma, correlated with preoperative diagnosis: an archival cross-sectional study.
382. Comparative histopathology of benign and malignant biliary strictures using epithelial atypia, periductal fibrosis and infiltrative glands, with resection diagnosis as reference: an archival diagnostic study.
383. Histopathological characteristics of chronic cholangitis in extrahepatic bile duct resections using inflammation, fibrosis and epithelial reactive changes: an archival cross-sectional study.
384. Frequency and distribution of biliary intraepithelial neoplasia in extrahepatic bile ducts adjacent to cholangiocarcinoma: an archival cross-sectional study using systematic mucosal examination.
385. Inter-observer agreement for distinguishing reactive biliary atypia from biliary intraepithelial neoplasia using standardized morphological criteria: an archival blinded microscopy study.
386. Histopathological spectrum of perihilar cholangiocarcinoma using tumour differentiation, perineural invasion, lymphovascular invasion and margin status: an archival cross-sectional study.
387. Histopathological spectrum of distal extrahepatic cholangiocarcinoma using grade, depth, vascular invasion and perineural invasion, correlated with pathological stage: an archival study.
388. Comparative histopathology of perihilar and distal extrahepatic cholangiocarcinoma using tumour grade, perineural invasion, lymphovascular invasion and nodal metastasis: an archival comparative study.
389. Frequency and pathological significance of perineural invasion in extrahepatic cholangiocarcinoma, correlated with tumour grade, margin status and nodal metastasis: an archival study.
390. Frequency and pathological significance of lymphovascular invasion in extrahepatic cholangiocarcinoma, correlated with tumour grade and nodal stage: a retrospective cross-sectional study.
391. Histological assessment of proximal and distal duct margins in extrahepatic cholangiocarcinoma and association with adjacent high-grade biliary intraepithelial neoplasia: an archival study.
392. Histopathological characteristics of nodal metastases in extrahepatic cholangiocarcinoma, correlated with primary tumour differentiation and perineural invasion: an archival paired-specimen study.
393. Diagnostic differentiation of cholangiocarcinoma from benign sclerosing biliary lesions using morphology and limited immunohistochemistry, with final surgical diagnosis as reference: an archival study.
394. Diagnostic utility of cytokeratin 7 and cytokeratin 19 for supporting biliary differentiation in extrahepatic adenocarcinoma, using final integrated diagnosis as reference: an archival study.
395. Correlation of serum carbohydrate antigen 19-9 with histological grade, nodal status and pathological stage in extrahepatic cholangiocarcinoma: a retrospective clinicopathological study.
396. Histopathological spectrum of intraductal papillary neoplasm of the bile duct using epithelial phenotype, grade and associated invasive carcinoma: an archival descriptive study.
397. Frequency of invasive carcinoma associated with intraductal papillary neoplasm of the bile duct in resection specimens: an archival cross-sectional study with systematic sampling.
398. Correlation of radiological biliary stricture length with histopathological tumour extent in extrahepatic cholangiocarcinoma resections: a retrospective radiology-pathology study.
399. Inter-observer agreement for histological grading and perineural invasion assessment in extrahepatic cholangiocarcinoma using standardized criteria: an archival blinded study.
400. Histopathology audit of bile duct resections for precursor lesions, tumour grade, invasion, margins, nodes and pathological staging completeness: a retrospective laboratory quality study.

Biliary Cytology and Biliary Strictures

401. Diagnostic accuracy of bile duct brush cytology for malignancy in biliary strictures against surgical biopsy or resection histopathology as reference standard: a retrospective cross-sectional study.
402. Cytomorphological spectrum of benign biliary brushings in patients with inflammatory or obstructive strictures, correlated with histopathology and clinical follow-up diagnosis: a retrospective study.
403. Histopathological outcomes of biliary brush cytology reported as atypical, using subsequent biopsy or resection histopathology as reference standard: an archival correlation study.
404. Histopathological outcomes of biliary brush cytology reported as suspicious for malignancy, using subsequent surgical pathology as reference standard: a retrospective study.
405. Sensitivity, specificity and predictive values of malignant biliary brush cytology for cholangiocarcinoma against histopathological diagnosis as reference standard: a retrospective diagnostic accuracy study.
406. Cytomorphological features associated with malignant biliary strictures using nuclear enlargement, irregularity and three-dimensional clusters, with histopathology as reference: an archival diagnostic study.
407. Analysis of false-negative biliary brush cytology in histologically confirmed cholangiocarcinoma, focusing on cellularity, degeneration and tumour differentiation: a retrospective discrepancy audit.
408. Analysis of false-positive biliary brush cytology in benign biliary strictures using retrospective slide review and histopathological correlation: a laboratory discrepancy audit.
409. Diagnostic contribution of cell block preparation in biliary brushing specimens compared with conventional smears, using histopathology as reference standard: a retrospective study.
410. Inter-observer agreement for classification of biliary brush cytology into benign, atypical, suspicious and malignant categories using standardized cytological criteria: an archival blinded study.
411. Correlation of stricture location with diagnostic sensitivity of biliary brush cytology in perihilar and distal extrahepatic bile duct lesions: a retrospective diagnostic study.
412. Comparative cytological features of benign inflammatory strictures and cholangiocarcinoma using cellularity, architecture and nuclear atypia, with histopathology as reference: an archival study.
413. Correlation of radiological malignant features of biliary strictures with brush cytology and final histopathological diagnosis: a retrospective radiology-cytology-pathology correlation study.
414. Diagnostic accuracy of combined brush cytology and tissue biopsy for malignant biliary strictures against surgical resection as reference standard: a retrospective comparative study.
415. Diagnostic utility of cytokeratin 7 immunocytochemistry on biliary cell blocks in morphologically suspicious cases, using histopathological diagnosis as reference: an archival study.
416. Diagnostic utility of p53 immunocytochemistry in atypical biliary brushings for malignancy against subsequent histopathological diagnosis as reference standard: an archival study.
417. Correlation of serum carbohydrate antigen 19-9 with biliary cytology category and final histopathological diagnosis in patients with biliary strictures: a retrospective study.
418. Adequacy of biliary brushing specimens assessed by cellularity and preservation, correlated with diagnostic sensitivity for malignancy: a retrospective laboratory study.
419. Diagnostic concordance between biliary brush cytology and resection histopathology for benign versus malignant biliary strictures: a retrospective paired-specimen agreement study.
420. Cytopathology audit of biliary brushings for adequacy, category distribution, histological concordance, false-negative diagnoses and turnaround time: a retrospective quality indicator study.

Paediatric Hepatobiliary Pathology

421. Histopathological spectrum of paediatric liver biopsies performed for persistent jaundice or abnormal liver tests, correlated with age and final clinical diagnosis: a retrospective cross-sectional study.
422. Histological spectrum of neonatal hepatitis using lobular disarray, giant-cell transformation and cholestasis, correlated with clinical and biochemical findings: an archival cross-sectional study.
423. Diagnostic differentiation of neonatal hepatitis from biliary atresia using ductular reaction, portal fibrosis and bile plugs, with operative diagnosis as reference: an archival diagnostic study.
424. Histopathological features of biliary atresia in wedge liver biopsies using bile duct proliferation, portal fibrosis and bile plugs, correlated with age at surgery: a retrospective study.
425. Correlation of portal fibrosis severity with age at surgical intervention in infants with histologically confirmed biliary atresia: an archival clinicopathological study.
426. Inter-observer agreement for histological features used to distinguish biliary atresia from neonatal hepatitis in infant liver biopsies: an archival blinded microscopy study.
427. Histopathological spectrum of paediatric cholestatic liver disease using canalicular cholestasis, duct injury and ductular reaction, correlated with final clinical diagnosis: a retrospective study.
428. Histological spectrum of congenital hepatic fibrosis using ductal plate abnormalities and portal fibrosis, correlated with clinical portal hypertension: an archival cross-sectional study.
429. Histopathological characteristics of ductal plate malformations in paediatric liver tissue, correlated with associated congenital hepatobiliary abnormalities: an archival descriptive study.
430. Histological spectrum of paediatric metabolic liver disease using steatosis, storage changes and fibrosis, correlated with established biochemical diagnosis: a retrospective cross-sectional study.
431. Histopathological spectrum of hepatoblastoma in resection specimens using epithelial and mixed epithelial-mesenchymal patterns, correlated with age and pathological stage: an archival study.
432. Distribution of foetal and embryonal epithelial patterns in hepatoblastoma and association with tumour necrosis and stage: an archival cross-sectional study.
433. Histomorphological characterization of mesenchymal hamartoma of liver using cystic architecture and mesenchymal stroma, correlated with radiological diagnosis: an archival study.
434. Diagnostic differentiation of mesenchymal hamartoma from other paediatric cystic liver lesions using routine histology and final surgical diagnosis as reference: an archival study.
435. Histopathological characteristics of undifferentiated embryonal sarcoma of liver using pleomorphic cells and myxoid stroma, correlated with final integrated diagnosis: an archival study.
436. Histopathological spectrum of vascular liver tumours in children using morphology and endothelial immunohistochemistry, with final integrated diagnosis as reference: an archival study.
437. Diagnostic concordance between preoperative imaging and final histopathology in paediatric focal liver lesions: a retrospective radiology-pathology agreement study.
438. Correlation of serum alpha-fetoprotein with histological tumour category in paediatric primary liver neoplasms: a retrospective clinicopathological study.
439. Inter-observer agreement for classifying common paediatric liver biopsy patterns using standardized morphological criteria: an archival blinded study.
440. Histopathology audit of paediatric liver biopsies and resections for adequacy, cholestasis evaluation, fibrosis assessment, tumour classification and clinicopathological correlation: a retrospective quality study.

Immunohistochemistry in Hepatobiliary Pathology

441. Diagnostic accuracy of arginase-1 immunohistochemistry for hepatocellular carcinoma against final integrated histopathological diagnosis in primary and metastatic liver tumours: an archival diagnostic study.
442. Diagnostic performance of hepatocyte paraffin 1 and arginase-1 for confirming hepatocellular differentiation in poorly differentiated liver malignancies: an archival comparative diagnostic study.
443. Diagnostic utility of glypican-3 immunohistochemistry for hepatocellular carcinoma against benign hepatocellular nodules and metastatic carcinoma: an archival comparative study.
444. Comparative expression of arginase-1, hepatocyte paraffin 1 and glypican-3 across hepatocellular carcinoma differentiation grades: an archival cross-sectional immunohistochemical study.
445. Diagnostic performance of cytokeratin 7 and cytokeratin 19 for cholangiocarcinoma against hepatocellular carcinoma, using final integrated diagnosis as reference: an archival study.
446. Diagnostic differentiation of hepatocellular carcinoma and cholangiocarcinoma using a limited panel of arginase-1, hepatocyte paraffin 1, cytokeratin 7 and cytokeratin 19: an archival study.
447. Diagnostic utility of special AT-rich sequence-binding protein 2 and caudal type homeobox 2 for colorectal adenocarcinoma metastatic to liver: an archival diagnostic accuracy study.
448. Diagnostic value of GATA binding protein 3 in breast carcinoma metastatic to liver, using documented primary breast carcinoma and integrated diagnosis as reference: an archival study.
449. Diagnostic value of thyroid transcription factor 1 in lung adenocarcinoma metastatic to liver, using documented pulmonary primary tumour as reference: an archival diagnostic study.
450. Diagnostic performance of synaptophysin and chromogranin for neuroendocrine tumour metastases in liver against final integrated histopathological diagnosis: an archival study.
451. Correlation of Ki-67 proliferation index with histological grade in metastatic well-differentiated neuroendocrine tumours involving liver: an archival cross-sectional study.
452. Diagnostic utility of cluster of differentiation 31 and erythroblast transformation-specific-related gene immunohistochemistry for primary hepatic vascular tumours against final integrated diagnosis: an archival study.
453. Diagnostic differentiation of hepatic vascular tumours from carcinoma using endothelial and epithelial immunohistochemical markers: an archival comparative diagnostic study.
454. Diagnostic utility of p53 immunohistochemistry for gallbladder dysplasia and carcinoma against consensus morphology-based diagnosis: an archival cross-sectional study.
455. Correlation of Ki-67 proliferation index with chronic cholecystitis, dysplasia and invasive gallbladder carcinoma: an archival comparative immunohistochemical study.
456. Diagnostic differentiation of primary gallbladder adenocarcinoma from colorectal metastasis using cytokeratin 7, cytokeratin 20, caudal type homeobox 2 and special AT-rich sequence-binding protein 2: an archival study.
457. Diagnostic utility of p57 or other routinely available trophic markers is excluded; instead, assessment of rational limited immunohistochemistry panels in common hepatobiliary tumours compared with final diagnosis: a retrospective audit study.
458. Concordance between morphology-only diagnosis and immunohistochemistry-supported diagnosis in difficult primary and metastatic hepatobiliary malignancies: an archival diagnostic impact study.
459. Frequency of redundant immunohistochemical stains in hepatobiliary tumour work-up and their contribution to final diagnosis: a retrospective laboratory utilisation audit.
460. Laboratory audit of hepatobiliary immunohistochemistry for panel size, diagnostic yield, repeat staining, turnaround time and concordance with final integrated diagnosis: a retrospective quality study.

Histopathology–Radiology Correlation in Hepatobiliary Disease

461. Diagnostic accuracy of ultrasonographic fatty liver grading against histological steatosis percentage in adults undergoing clinically indicated liver biopsy: a retrospective radiology-pathology study.
462. Correlation of liver surface nodularity and coarse echotexture on ultrasonography with histological fibrosis stage in chronic liver disease: a retrospective radiology-pathology cross-sectional study.
463. Diagnostic accuracy of imaging-based cirrhosis diagnosis against histological cirrhosis in patients with available liver tissue: a retrospective diagnostic accuracy study.
464. Correlation of radiological focal liver lesion categorization with final histopathological diagnosis in patients undergoing biopsy or resection: a retrospective radiology-pathology concordance study.
465. Diagnostic accuracy of radiological diagnosis of hepatocellular carcinoma against resection or biopsy histopathology as reference standard in sampled liver masses: a retrospective study.
466. Correlation of radiological hepatocellular carcinoma size and multiplicity with gross and microscopic tumour measurements in liver resections: a retrospective radiology-pathology study.
467. Correlation of imaging-detected vascular invasion with histopathological vascular invasion in hepatocellular carcinoma resection specimens: a retrospective diagnostic accuracy study.
468. Diagnostic accuracy of radiological diagnosis of intrahepatic cholangiocarcinoma against resection histopathology as reference standard: a retrospective study.
469. Correlation of radiological tumour size and satellite lesions with histopathological findings in intrahepatic cholangiocarcinoma: a retrospective radiology-pathology cross-sectional study.
470. Diagnostic accuracy of imaging for metastatic liver disease against core biopsy or resection histopathology as reference standard: a retrospective cross-sectional study.
471. Correlation of radiological number and distribution of liver metastases with histological primary-site diagnosis in tissue-confirmed metastatic malignancy: a retrospective study.
472. Diagnostic accuracy of ultrasonography for acute cholecystitis against cholecystectomy histopathology as reference standard: a retrospective hospital-based study.
473. Correlation of gallbladder wall thickness on ultrasonography with histological inflammation, fibrosis and muscular hypertrophy in cholecystectomy specimens: a retrospective study.
474. Diagnostic accuracy of imaging for xanthogranulomatous cholecystitis against cholecystectomy histopathology as reference standard: a retrospective radiology-pathology study.
475. Diagnostic accuracy of radiological suspicion of gallbladder carcinoma against cholecystectomy or radical cholecystectomy histopathology as reference standard: a retrospective study.
476. Correlation of focal versus diffuse gallbladder wall thickening on imaging with chronic cholecystitis, adenomyomatosis, xanthogranulomatous inflammation and carcinoma: a retrospective study.
477. Diagnostic accuracy of imaging for malignant biliary stricture against biopsy or resection histopathology as reference standard: a retrospective radiology-pathology study.
478. Correlation of level and length of biliary stricture on imaging with final histopathological diagnosis and tumour extent in resected bile duct lesions: a retrospective study.
479. Diagnostic concordance of preoperative imaging and histopathology for choledochal cyst and other surgically resected congenital biliary abnormalities: a retrospective study.
480. Radiology-pathology audit of hepatobiliary surgical specimens assessing lesion localisation, benign versus malignant categorization, tumour extent and major diagnostic discordances: a retrospective quality study.

Hepatobiliary Surgical Pathology and Clinical-Laboratory Correlation

481. Histopathological spectrum of liver biopsies in a tertiary teaching hospital, correlated with clinical indication, biochemical profile and final clinicopathological diagnosis: a retrospective cross-sectional study.
482. Histopathological spectrum of partial hepatectomy and liver resection specimens, categorized into primary malignancy, metastasis and benign lesions, with preoperative radiological correlation: an archival cross-sectional study.
483. Diagnostic concordance between liver core biopsy and subsequent resection for hepatocellular carcinoma, cholangiocarcinoma and metastatic malignancy: a retrospective paired-specimen agreement study.
484. Histopathological spectrum of routine cholecystectomy specimens, including inflammation, metaplasia, dysplasia and incidental carcinoma, correlated with preoperative clinical and imaging diagnosis: a retrospective study.
485. Diagnostic concordance between preoperative gallbladder imaging and final cholecystectomy histopathology for chronic cholecystitis, adenomyomatosis, xanthogranulomatous cholecystitis and carcinoma: a retrospective study.
486. Histopathological spectrum of radical cholecystectomy specimens using tumour type, grade, invasion, margins and nodal status, correlated with preoperative staging: an archival cross-sectional study.
487. Histopathological spectrum of extrahepatic bile duct resection specimens, including benign strictures, precursor lesions and cholangiocarcinoma, correlated with preoperative diagnosis: an archival cross-sectional study.
488. Histopathological spectrum of hepatic metastasectomy specimens using primary tumour site, viable tumour percentage and treatment-related changes, correlated with clinical treatment history: an archival study.
489. Correlation of serum bilirubin, alkaline phosphatase and aminotransferases with histological cholestatic, hepatitic and obstructive patterns in liver biopsies: a retrospective clinicopathological cross-sectional study.
490. Correlation of serum albumin, platelet count and coagulation parameters with histological fibrosis stage in adult chronic liver disease: a retrospective clinicopathological study.
491. Correlation of alpha-fetoprotein concentration with tumour size, differentiation and vascular invasion in histologically confirmed hepatocellular carcinoma: a retrospective clinicopathological study.
492. Correlation of carbohydrate antigen 19-9 concentration with tumour size, grade and stage in histologically confirmed cholangiocarcinoma and gallbladder carcinoma: a retrospective study.
493. Correlation of carcinoembryonic antigen concentration with histological diagnosis and metastatic burden in colorectal carcinoma metastatic to liver: a retrospective clinicopathological study.
494. Diagnostic accuracy of routine serum fibrosis-related parameters for advanced fibrosis against histological fibrosis staging in chronic liver disease: a retrospective diagnostic accuracy study.
495. Histopathology audit of liver biopsy specimens for adequacy, special stains, fibrosis staging, clinicopathological correlation and standardized reporting completeness: a retrospective laboratory quality study.
496. Histopathology audit of cholecystectomy specimens for gross description, representative sampling, metaplasia, dysplasia, incidental carcinoma and turnaround time: a retrospective laboratory quality study.
497. Histopathology audit of liver tumour resections for tumour type, grade, vascular invasion, margins, background liver and pathological staging completeness: a retrospective quality study.
498. Histopathology audit of radical cholecystectomy specimens for tumour dimensions, depth of invasion, liver involvement, perineural invasion, lymphovascular invasion, margins and nodal status: a retrospective study.
499. Histopathology audit of bile duct resections for dysplasia, invasive carcinoma, perineural invasion, vascular invasion, surgical margins, nodes and pathological staging completeness: a retrospective quality study.
500. Clinicopathological concordance audit of major hepatobiliary specimens comparing clinical diagnosis, imaging impression, laboratory findings and final histopathological diagnosis in a tertiary teaching hospital: a retrospective study.

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