Pathology Research Topics For MD Pathology/DNB Pathology

pathology thesis topics

This master page brings together MD pathology thesis topics and MD pathology research topics across haematology, transfusion medicine, cytopathology, surgical pathology, organ-system pathology, paediatric and perinatal pathology, body fluids, special stains and laboratory quality assurance for MD Pathology and DNB Pathology candidates. The strongest topics are designed around specimens, slides, laboratory parameters and investigations already generated during routine patient care so that the project can be completed within one thesis period without depending on expensive research-only testing. Once a topic is selected, the same question can be converted into an MD pathology protocol or MD pathology synopsis with explicit specimen selection, reference-standard and analysis rules.

Last reviewed and updated: September 2026 · 2026–27 admissions

Haematology: Anaemia, Red Cell Disorders and Haemoglobinopathies

  1. Diagnostic accuracy of Mentzer index in adults with microcytic hypochromic anaemia using high performance liquid chromatography and serum ferritin as reference standards for distinguishing beta thalassaemia trait from iron deficiency anaemia: a hospital-based cross-sectional study
  2. Diagnostic accuracy of red cell distribution width in adults with microcytic anaemia using serum ferritin and high performance liquid chromatography as reference standards for differentiation of iron deficiency anaemia from beta thalassaemia trait: a cross-sectional study
  3. Comparative diagnostic accuracy of Mentzer, Shine and Lal, and England and Fraser indices in adults with microcytosis against high performance liquid chromatography for detection of beta thalassaemia trait: a cross-sectional study
  4. Correlation of mean corpuscular volume with serum ferritin concentration in adults with laboratory-confirmed iron deficiency anaemia for assessment of severity at initial diagnosis: a hospital-based cross-sectional correlation study
  5. Correlation of red cell distribution width with haemoglobin concentration and peripheral smear anisopoikilocytosis in adults with iron deficiency anaemia for assessment of morphological severity at diagnosis: a cross-sectional study
  6. Diagnostic accuracy of peripheral blood smear microcytosis and hypochromia grading in adults with suspected iron deficiency anaemia against serum ferritin as reference standard for iron deficiency: a cross-sectional study
  7. Agreement between automated red cell indices and manual peripheral smear grading in adults with anaemia for classification as microcytic, normocytic or macrocytic at initial laboratory evaluation: an analyser-versus-manual agreement study
  8. Correlation of automated reticulocyte percentage with corrected reticulocyte count calculated from routine haematology parameters in adults with anaemia for assessment of marrow response at diagnosis: a cross-sectional correlation study
  9. Diagnostic accuracy of red cell distribution width to discriminate megaloblastic anaemia from other macrocytic anaemias in adults using bone marrow examination and serum vitamin assays where routinely available as reference standards: a cross-sectional study
  10. Correlation of mean corpuscular volume with bone marrow megaloblastic changes in adults undergoing routine marrow examination for macrocytic anaemia for prediction of megaloblastic morphology: a cross-sectional correlation study
  11. Frequency and morphological severity of hypersegmented neutrophils on peripheral smear in adults with bone marrow-confirmed megaloblastic anaemia compared with non-megaloblastic macrocytic anaemia: a comparative cross-sectional study
  12. Diagnostic accuracy of macro-ovalocytes and hypersegmented neutrophils on peripheral smear in adults with macrocytosis against bone marrow megaloblastic morphology for diagnosis of megaloblastic anaemia: a cross-sectional study
  13. Correlation of pancytopenia severity with marrow megaloblastic change in adults with nutritional megaloblastic anaemia undergoing routine bone marrow examination: a hospital-based cross-sectional correlation study
  14. Diagnostic accuracy of automated mean corpuscular haemoglobin concentration for hereditary spherocytosis screening in patients with spherocytes on peripheral smear using osmotic fragility testing where routinely performed as reference standard: a cross-sectional study
  15. Correlation of nucleated red blood cell count with haemoglobin concentration and reticulocyte response in hospitalised adults with severe anaemia for assessment of haematological stress at initial evaluation: a cross-sectional study
  16. Prevalence and haematological correlates of dimorphic anaemia among adults with anaemia diagnosed on peripheral smear using automated red cell indices as comparator for morphological classification: a hospital-based cross-sectional study
  17. Agreement between peripheral smear morphological classification and automated red cell indices in adults with anaemia for identification of microcytic, macrocytic and dimorphic patterns at diagnosis: a cross-sectional agreement study
  18. Correlation of red cell distribution width with degree of anisocytosis graded on peripheral smear in adults with anaemia for assessment of analyser-derived morphological concordance: an analyser-versus-manual correlation study
  19. Diagnostic accuracy of Mentzer index in children with microcytic anaemia using high performance liquid chromatography and serum ferritin as reference standards for distinguishing beta thalassaemia trait from iron deficiency anaemia: a cross-sectional study
  20. Comparative performance of Green and King, Mentzer, and red cell distribution width indices in children with microcytosis against high performance liquid chromatography for identification of beta thalassaemia trait: a cross-sectional diagnostic accuracy study
  21. Prevalence and haematological profile of haemoglobin variants detected by routinely performed high performance liquid chromatography among patients investigated for chronic anaemia: a retrospective record-based study
  22. Correlation of high performance liquid chromatography haemoglobin fraction patterns with peripheral smear morphology in patients with sickle cell disease and sickle cell trait for haematological phenotyping: a cross-sectional study
  23. Correlation of haemoglobin concentration with sickle cell percentage estimated on peripheral smear where routinely reported in patients with sickling disorders using high performance liquid chromatography classification as comparator: a cross-sectional study
  24. Diagnostic accuracy of sickling test in patients with suspected sickle haemoglobinopathy using high performance liquid chromatography as reference standard for detection of sickle haemoglobin: a hospital-based cross-sectional study
  25. Agreement between peripheral smear findings and high performance liquid chromatography patterns in patients investigated for haemoglobinopathies for classification of thalassaemic and sickling disorders: a cross-sectional agreement study
  26. Prevalence of beta thalassaemia trait among adults with unexplained microcytosis and normal or near-normal haemoglobin concentration using high performance liquid chromatography as diagnostic standard: a hospital-based cross-sectional study
  27. Diagnostic accuracy of mean corpuscular volume below routine laboratory threshold in adults with normal haemoglobin for detection of beta thalassaemia trait using high performance liquid chromatography as reference standard: a cross-sectional study
  28. Diagnostic accuracy of red blood cell count elevation in microcytic adults for detection of beta thalassaemia trait using high performance liquid chromatography and serum ferritin as reference standards: a cross-sectional study
  29. Correlation of haemoglobin A2 percentage with mean corpuscular volume and mean corpuscular haemoglobin in patients with beta thalassaemia trait detected by high performance liquid chromatography: a cross-sectional correlation study
  30. Prevalence and morphological correlates of iron deficiency among women of reproductive age with anaemia using serum ferritin as reference standard and peripheral smear parameters as index findings: a hospital-based cross-sectional study
  31. Diagnostic accuracy of peripheral smear hypochromia grading in women of reproductive age with anaemia using serum ferritin as reference standard for iron deficiency: a cross-sectional study
  32. Correlation of haemoglobin concentration with serum ferritin and red cell distribution width in pregnant women undergoing routine anaemia evaluation for assessment of iron deficiency severity: a cross-sectional observational study
  33. Diagnostic accuracy of automated microcytic red cell parameters in pregnant women with anaemia against serum ferritin for detection of iron deficiency at initial antenatal laboratory assessment: a cross-sectional study
  34. Prevalence and haematological correlates of anaemia among elderly patients attending a tertiary hospital using automated red cell indices and peripheral smear classification as complementary assessment methods: a retrospective record-based study
  35. Agreement between automated and manual packed cell volume measurements in anaemic patients using routine laboratory samples for assessment of analytical concordance across haemoglobin concentration categories: a method-comparison study
  36. Agreement between automated haemoglobin measurement and cyanmethemoglobin method where routinely available in patient samples spanning anaemic and non-anaemic ranges for assessment of laboratory comparability: a method-comparison cross-sectional study
  37. Correlation of red cell distribution width with erythrocyte sedimentation rate in adults with anaemia of chronic inflammatory conditions for assessment of haematological variation at diagnosis: a cross-sectional study
  38. Diagnostic accuracy of red cell distribution width and mean corpuscular volume combination for distinguishing iron deficiency anaemia from anaemia of chronic disease using serum ferritin and inflammatory markers as reference standards: a cross-sectional study
  39. Correlation of peripheral smear polychromasia grading with automated reticulocyte count in patients with haemolytic anaemia for assessment of marrow regenerative response at diagnosis: a cross-sectional correlation study
  40. Agreement between manual reticulocyte count and automated reticulocyte count in patients undergoing routine reticulocyte testing for assessment of analytical concordance across anaemia categories: a laboratory-based method-comparison study
  41. Diagnostic accuracy of peripheral smear schistocyte grading in patients with suspected microangiopathic haemolysis using clinical diagnosis and routine haemolysis parameters as reference standard for significant fragmentation: a cross-sectional study
  42. Inter-observer agreement in grading anisocytosis, poikilocytosis and hypochromia on peripheral smears from adults with anaemia using predefined morphological criteria and automated indices as external comparators: an observer-agreement study
  43. Inter-observer agreement in identification of target cells, tear-drop cells and elliptocytes on peripheral smears from anaemic patients using consensus microscopy as reference classification: a cross-sectional observer-agreement study
  44. Prevalence and morphological patterns of anaemia in patients with chronic kidney disease using automated red cell indices and peripheral smear examination for classification at routine laboratory evaluation: a retrospective record-based study
  45. Correlation of haemoglobin concentration and red cell indices with chronic kidney disease stage documented in routine records for assessment of anaemia severity across disease categories: a retrospective observational study
  46. Diagnostic accuracy of red cell distribution width for identifying mixed nutritional anaemia in adults using serum ferritin, vitamin assays where available and peripheral smear morphology as composite reference standard: a cross-sectional study
  47. Correlation of platelet count elevation with severity of iron deficiency measured by serum ferritin in adults with iron deficiency anaemia for assessment of reactive thrombocytosis at diagnosis: a cross-sectional study
  48. Correlation of leucocyte and platelet abnormalities with haemoglobin severity in adults with megaloblastic anaemia confirmed by marrow morphology for assessment of multilineage involvement: a cross-sectional correlation study
  49. Prevalence of incidental microcytosis among routine complete blood count specimens and proportion attributable to iron deficiency or beta thalassaemia trait using available ferritin and high performance liquid chromatography results: a retrospective study
  50. Diagnostic yield of reflex peripheral smear review among specimens meeting automated microcytosis criteria compared with final laboratory diagnosis for detecting iron deficiency, thalassaemic morphology and other red cell abnormalities: a laboratory audit

Haematological Malignancies and Bone Marrow Pathology

  1. Correlation of peripheral blood blast percentage with bone marrow blast percentage in adults newly evaluated for acute leukaemia using routine marrow aspiration as reference for disease burden at diagnosis: a cross-sectional study
  2. Agreement between bone marrow aspiration and trephine biopsy in adults with suspected acute leukaemia for assessment of marrow cellularity and blast infiltration at initial diagnosis: a cross-sectional agreement study
  3. Diagnostic yield of bone marrow trephine biopsy following inadequate or dry-tap aspiration in patients investigated for haematological disorders using final integrated marrow diagnosis as reference standard: a retrospective observational study
  4. Correlation of marrow cellularity estimated on aspiration smears with trephine biopsy cellularity in adults undergoing routine bone marrow examination for cytopenias and haematological malignancies: a cross-sectional correlation study
  5. Agreement between two observers in bone marrow blast counting among newly diagnosed acute leukaemia cases using consensus microscopy as reference classification: an inter-observer agreement study
  6. Correlation of peripheral leucocyte count with bone marrow blast percentage in adults with acute myeloid leukaemia diagnosed by routine morphology and basic immunophenotypic information where available: a cross-sectional study
  7. Morphological concordance between peripheral blood and bone marrow findings in adults with acute myeloid leukaemia using bone marrow examination as reference standard for blast lineage and maturation: a cross-sectional study
  8. Diagnostic accuracy of peripheral smear blast morphology in suspected acute leukaemia using bone marrow morphology and routine immunophenotypic classification where available as reference standard for lineage assignment: a cross-sectional study
  9. Correlation of platelet count and haemoglobin concentration with bone marrow blast percentage in adults with newly diagnosed acute leukaemia for assessment of marrow failure severity: a cross-sectional correlation study
  10. Frequency and diagnostic significance of Auer rods on peripheral blood and marrow smears in acute myeloid leukaemia using integrated final diagnosis as reference classification: a retrospective morphological study
  11. Agreement between bone marrow aspiration and trephine biopsy in patients with suspected myelodysplastic syndromes for assessment of cellularity, dysplasia and blast percentage at diagnosis: a cross-sectional agreement study
  12. Inter-observer agreement in grading dyserythropoiesis, dysgranulopoiesis and dysmegakaryopoiesis on marrow aspirates from patients investigated for unexplained cytopenias using consensus morphology as reference assessment: an observer-agreement study
  13. Correlation of peripheral cytopenia pattern with marrow dysplasia severity in adults evaluated for suspected myelodysplastic syndromes using routine marrow morphology for diagnostic categorisation: a cross-sectional study
  14. Diagnostic contribution of Perls Prussian blue stain on bone marrow aspirates from patients with unexplained anaemia compared with routine morphology for detection and grading of marrow iron stores: a cross-sectional study
  15. Agreement between aspirate smear iron grading and trephine biopsy iron assessment using Perls Prussian blue stain in patients undergoing routine marrow evaluation for anaemia: a method-comparison study
  16. Correlation of marrow iron grade with serum ferritin in adults undergoing bone marrow examination for anaemia using Perls Prussian blue stain as morphological assessment: a cross-sectional correlation study
  17. Prevalence and clinicopathological correlates of marrow granulomas among bone marrow biopsies using haematoxylin and eosin morphology with Ziehl-Neelsen stain as adjunct for mycobacterial organisms: an archival study
  18. Diagnostic yield of Ziehl-Neelsen stain in bone marrow granulomas identified on trephine biopsies compared with final clinicopathological diagnosis for detection of mycobacterial infection: a retrospective diagnostic study
  19. Correlation of bone marrow fibrosis grade assessed by reticulin stain with splenomegaly and blood count abnormalities in patients with myeloproliferative neoplasms: an archival cross-sectional study
  20. Inter-observer agreement in bone marrow reticulin fibrosis grading among patients with myeloproliferative neoplasms using consensus review as reference assessment: an archival observer-agreement study
  21. Agreement between marrow aspirate megakaryocyte morphology and trephine biopsy megakaryocytic patterns in suspected myeloproliferative neoplasms using integrated final diagnosis as comparator: a cross-sectional study
  22. Correlation of platelet count with megakaryocyte number and morphology on bone marrow examination in patients with suspected essential thrombocythaemia: a hospital-based cross-sectional study
  23. Correlation of haemoglobin concentration with marrow fibrosis grade in patients with primary myelofibrosis using reticulin-stained trephine sections for assessment of disease-associated marrow alteration: an archival study
  24. Frequency of dry tap and its pathological causes among routine bone marrow aspirations using corresponding trephine biopsy diagnosis as reference standard: a retrospective record-based study
  25. Diagnostic yield of trephine biopsy in pancytopenic patients with non-diagnostic aspiration compared with final clinicopathological diagnosis for identification of marrow infiltration, fibrosis and aplasia: a retrospective study
  26. Spectrum of bone marrow findings in adults with pancytopenia using aspiration and trephine biopsy concordance for classification of nutritional, aplastic, infiltrative and malignant causes: a cross-sectional study
  27. Agreement between bone marrow aspiration and trephine biopsy in adults with pancytopenia for identifying megaloblastic change, aplasia, fibrosis and malignant infiltration: a cross-sectional agreement study
  28. Correlation of absolute neutrophil count, platelet count and haemoglobin concentration with marrow cellularity in adults with pancytopenia undergoing routine bone marrow examination: a cross-sectional correlation study
  29. Diagnostic accuracy of peripheral smear leukoerythroblastic pattern for marrow infiltration using trephine biopsy as reference standard in patients undergoing investigation for suspected metastatic or haematological disease: a cross-sectional study
  30. Prevalence of metastatic solid tumour deposits in bone marrow biopsies and correlation with peripheral blood leukoerythroblastic changes using histopathological examination as diagnostic reference: an archival study
  31. Diagnostic yield of routine bone marrow examination in patients with pyrexia of unknown origin using final clinical diagnosis as comparator for detection of haematological malignancy and granulomatous disease: a retrospective study
  32. Morphological patterns of plasma cell proliferation in marrow aspirates and trephine biopsies from patients with plasma cell neoplasms using routine immunohistochemistry where available as reference classification: an archival study
  33. Correlation of marrow plasma cell percentage with haemoglobin, creatinine and calcium values in newly diagnosed plasma cell myeloma using routine diagnostic records: a retrospective cross-sectional study
  34. Agreement between aspirate and trephine estimates of plasma cell percentage in plasma cell myeloma using routine morphology and basic immunohistochemistry as comparator: an archival agreement study
  35. Correlation of rouleaux formation graded on peripheral smear with marrow plasma cell percentage in patients with plasma cell myeloma for assessment of morphological association at diagnosis: a cross-sectional study
  36. Diagnostic accuracy of peripheral smear rouleaux formation for detecting plasma cell myeloma among adults undergoing marrow examination using integrated final marrow diagnosis as reference standard: a cross-sectional study
  37. Frequency and morphological spectrum of marrow involvement by non-Hodgkin lymphomas using trephine histopathology and basic immunohistochemistry as reference classification: an archival cross-sectional study
  38. Agreement between bone marrow aspiration and trephine biopsy for detection of marrow involvement in patients with lymphoma undergoing routine staging evaluation: a retrospective diagnostic agreement study
  39. Diagnostic yield of unilateral bone marrow trephine biopsy for detecting lymphoma involvement using integrated histopathological and clinical staging records as reference assessment: a retrospective study
  40. Correlation of peripheral blood lymphocytosis with marrow infiltration percentage in chronic lymphocytic leukaemia using routine bone marrow examination as morphological comparator: a cross-sectional study
  41. Inter-observer agreement in marrow lymphocyte percentage estimation among chronic lymphoproliferative disorders using consensus microscopy as reference assessment: an observer-agreement study
  42. Correlation of total leucocyte count with splenic enlargement and marrow myeloid-to-erythroid ratio in chronic myeloid leukaemia at initial diagnosis: a retrospective cross-sectional study
  43. Agreement between peripheral smear phase assessment and bone marrow morphology in chronic myeloid leukaemia using integrated clinical diagnosis as reference classification: a cross-sectional agreement study
  44. Frequency of eosinophilia and basophilia on peripheral smear in chronic myeloid leukaemia and correlation with marrow differential counts at initial diagnosis: a cross-sectional study
  45. Inter-observer agreement in bone marrow cellularity estimation on trephine biopsies from adults with haematological disorders using consensus percentage cellularity as reference assessment: an archival study
  46. Comparison of marrow aspirate smear, touch imprint and trephine biopsy morphology in haematological malignancies using final integrated diagnosis as reference standard for diagnostic adequacy: a cross-sectional study
  47. Diagnostic yield of trephine touch imprints in cases with inadequate marrow aspiration compared with trephine histopathology for detecting acute leukaemia, lymphoma and metastatic malignancy: a retrospective study
  48. Prevalence and morphological causes of haemophagocytosis in bone marrow aspirates from patients with cytopenias using clinical diagnosis and laboratory records as comparators: a retrospective cross-sectional study
  49. Correlation of marrow haemophagocytosis grade with cytopenia severity and serum ferritin where available in patients evaluated for haemophagocytic syndromes: a retrospective observational study
  50. Audit of bone marrow aspiration and trephine biopsy adequacy in a teaching hospital using predefined specimen-quality criteria and final diagnostic yield as outcome measures: a retrospective laboratory quality study

Coagulation, Platelets and Thrombocytopenia

  1. Correlation of automated platelet count with manual peripheral smear platelet estimate in thrombocytopenic patients using repeat microscopy as reference assessment for severity classification: an analyser-versus-manual agreement study
  2. Agreement between automated platelet counts obtained from routine analyser channels and manual platelet estimates in patients with platelet counts below the laboratory reference interval: a laboratory method-comparison study
  3. Diagnostic accuracy of peripheral smear platelet estimate for clinically significant thrombocytopenia using automated platelet count as reference standard in hospitalised adults: a cross-sectional study
  4. Correlation of mean platelet volume with platelet count in dengue patients with laboratory-confirmed infection for assessment of thrombocytopenia severity at presentation: a monsoon-season cross-sectional study
  5. Correlation of platelet distribution width with platelet count in dengue patients for assessment of platelet size heterogeneity across thrombocytopenia grades: a monsoon-season cross-sectional study
  6. Diagnostic performance of mean platelet volume for differentiating dengue-associated thrombocytopenia from non-dengue febrile thrombocytopenia using routine clinical diagnosis as reference classification: a comparative cross-sectional study
  7. Comparative platelet indices in dengue and malaria patients with thrombocytopenia using peripheral smear or routine antigen-based diagnosis as disease reference standards: a monsoon-season cross-sectional study
  8. Correlation of platelet count with peripheral smear parasitaemia grading in malaria patients for assessment of thrombocytopenia severity at initial diagnosis: a monsoon-season cross-sectional study
  9. Diagnostic accuracy of thrombocytopenia for identifying malaria among febrile patients undergoing routine peripheral smear examination using parasite demonstration as reference standard: a cross-sectional study
  10. Correlation of platelet count with sepsis severity documented at initial admission in adults with culture-supported or clinically diagnosed sepsis for assessment of haematological derangement: a retrospective cross-sectional study
  11. Comparative mean platelet volume and platelet distribution width in sepsis-related thrombocytopenia and dengue-related thrombocytopenia using routine final clinical diagnosis as comparator: a cross-sectional study
  12. Agreement between automated and manual platelet counts in samples showing platelet clumps or analyser flags using peripheral smear review as reference assessment: a laboratory-based agreement study
  13. Frequency and causes of pseudothrombocytopenia among samples with low automated platelet counts using repeat anticoagulated samples where routinely requested and peripheral smear examination as reference: a laboratory audit
  14. Diagnostic yield of routine peripheral smear review in samples with severe automated thrombocytopenia for detecting platelet clumping, giant platelets and spurious counts: a cross-sectional laboratory study
  15. Correlation of immature platelet fraction where routinely available with platelet count in immune thrombocytopenia using bone marrow findings where clinically performed as comparator for peripheral destruction: a cross-sectional study
  16. Correlation of megakaryocyte number and morphology on bone marrow examination with peripheral platelet count in patients investigated for isolated thrombocytopenia: a cross-sectional observational study
  17. Diagnostic contribution of bone marrow megakaryocyte morphology in thrombocytopenic patients using final clinical diagnosis as comparator for immune destruction, marrow failure and infiltrative causes: a retrospective study
  18. Comparative bone marrow megakaryocyte patterns in immune thrombocytopenia and aplastic anaemia using final clinical diagnosis as reference classification: a retrospective cross-sectional study
  19. Correlation of platelet count with bleeding manifestations documented at presentation among patients with immune thrombocytopenia for assessment of clinicopathological association: a retrospective observational study
  20. Correlation of mean platelet volume with bone marrow megakaryocyte number in patients with isolated thrombocytopenia undergoing routine marrow examination: a cross-sectional correlation study
  21. Prevalence and causes of prolonged prothrombin time among hospitalised adults using mixing studies and routine clinical diagnosis where available as reference classification: a retrospective record-based study
  22. Prevalence and causes of prolonged activated partial thromboplastin time among hospitalised adults using mixing studies and final clinical diagnosis where available as reference classification: a retrospective study
  23. Agreement between manual and automated prothrombin time measurement in routine patient plasma samples across normal and prolonged ranges for assessment of analytical concordance: a method-comparison study
  24. Agreement between manual and automated activated partial thromboplastin time measurement in routine patient plasma samples across normal and prolonged ranges for assessment of analytical concordance: a method-comparison study
  25. Correlation of prothrombin time prolongation with platelet count in adults with chronic liver disease using routine liver function results as clinical comparators for severity assessment: a cross-sectional study
  26. Correlation of activated partial thromboplastin time with platelet count in adults with sepsis-associated coagulopathy using routine clinical diagnosis as disease comparator: a cross-sectional study
  27. Frequency of simultaneous prothrombin time and activated partial thromboplastin time prolongation among patients with liver disease, sepsis and disseminated intravascular coagulation using final clinical diagnosis as comparator: a retrospective study
  28. Diagnostic accuracy of platelet count and prothrombin time combination for detecting clinically diagnosed disseminated intravascular coagulation using routine coagulation criteria as reference standard: a cross-sectional study
  29. Correlation of fibrinogen concentration where routinely measured with platelet count and prothrombin time in patients with disseminated intravascular coagulation for assessment of coagulation derangement: a retrospective observational study
  30. Correlation of D-dimer concentration where routinely measured with platelet count in patients evaluated for disseminated intravascular coagulation using routine clinical diagnosis as comparator: a retrospective study
  31. Prevalence of coagulation abnormalities among patients with chronic liver disease using prothrombin time, activated partial thromboplastin time and platelet count compared with documented disease severity: a cross-sectional study
  32. Correlation of prothrombin time international normalised ratio with histological cirrhosis or documented chronic liver disease category in patients undergoing routine evaluation: a retrospective clinicopathological study
  33. Prevalence of coagulation test abnormalities in nephrotic syndrome using prothrombin time and activated partial thromboplastin time compared with routine clinical diagnosis and serum albumin: a cross-sectional study
  34. Correlation of platelet count and coagulation parameters with peripheral smear findings in patients with severe malaria using parasite demonstration as reference diagnostic standard: a monsoon-season study
  35. Correlation of platelet nadir documented during admission with initial mean platelet volume in dengue patients for assessment of early platelet-index association without extended follow-up: a retrospective observational study
  36. Diagnostic accuracy of admission mean platelet volume for severe thrombocytopenia developing during routine dengue admission using lowest platelet count within five days as outcome measure: a retrospective study
  37. Comparative platelet count recovery patterns within five days in dengue patients stratified by baseline mean platelet volume using routine serial complete blood counts as outcome assessment: a retrospective observational study
  38. Frequency and morphology of giant platelets on peripheral smear in immune thrombocytopenia compared with hypoproliferative thrombocytopenia using final clinical or marrow diagnosis as reference classification: a comparative study
  39. Diagnostic accuracy of giant platelet proportion on peripheral smear for differentiating peripheral destruction from marrow hypoproduction using bone marrow examination where clinically performed as reference standard: a cross-sectional study
  40. Inter-observer agreement in manual peripheral smear platelet estimation among thrombocytopenic samples using automated platelet count and consensus microscopy as comparators: an observer-agreement study
  41. Inter-observer agreement in identification of platelet clumps and giant platelets on peripheral smears from flagged samples using consensus microscopy as reference assessment: a laboratory agreement study
  42. Prevalence and causes of thrombocytosis among routine complete blood count specimens using peripheral smear confirmation and clinical records for classification as reactive or clonal: a retrospective study
  43. Correlation of platelet count with serum ferritin in iron deficiency anaemia patients for assessment of reactive thrombocytosis at diagnosis: a cross-sectional correlation study
  44. Correlation of platelet count with total leucocyte count in patients with acute bacterial infections using final clinical diagnosis as comparator for reactive haematological changes: a cross-sectional study
  45. Diagnostic yield of peripheral smear review among samples with automated thrombocytosis for detecting spurious counts, giant platelets and associated morphological abnormalities: a laboratory audit
  46. Frequency of anticoagulant-related sample rejection in routine coagulation testing using predefined preanalytical quality criteria and repeat specimen requirement as outcome measure: a retrospective laboratory audit
  47. Association of underfilled citrate tubes with prothrombin time and activated partial thromboplastin time prolongation using correctly filled repeat samples as reference measurements: a laboratory method-comparison study
  48. Audit of critical platelet count reporting in a teaching hospital using documented communication time against institutional policy as reference standard for compliance: a retrospective quality-improvement study
  49. Audit of turnaround time for emergency coagulation tests using laboratory information timestamps against predefined institutional targets as reference standards for service performance: a retrospective study
  50. Frequency and causes of coagulation sample rejection in a teaching hospital using predefined specimen acceptability criteria and repeat collection rates as quality outcomes: a retrospective laboratory audit

Transfusion Medicine and Blood Bank Pathology

  1. Prevalence and causes of blood donor deferral among prospective voluntary and replacement donors using blood bank eligibility criteria as reference standards: a retrospective record-based study
  2. Comparative prevalence of temporary and permanent donor deferral among male and female blood donors using national blood donor selection criteria for classification: a retrospective cross-sectional study
  3. Prevalence of anaemia-related donor deferral among prospective female donors using pre-donation haemoglobin testing against blood bank eligibility thresholds as reference standard: a retrospective study
  4. Correlation of donor age and haemoglobin concentration with donation eligibility among prospective blood donors using routine pre-donation screening criteria as comparator: a cross-sectional study
  5. Prevalence and demographic correlates of hypertension-related donor deferral using routine pre-donation blood pressure measurements and eligibility criteria as reference standards: a retrospective study
  6. Prevalence of low body weight as a cause of donor deferral using routine donor screening measurements and national eligibility criteria as reference standards: a retrospective audit
  7. Seasonal variation in voluntary blood donation and donor deferral using monthly blood bank records and predefined eligibility criteria as outcome measures: a retrospective observational study
  8. Prevalence of transfusion-transmitted infection markers among blood donors using routinely performed serological screening assays and confirmatory blood bank records as diagnostic comparators: a retrospective study
  9. Seroprevalence trends of hepatitis B surface antigen among blood donors using routine screening assays and annual donation records for temporal comparison: a retrospective record-based study
  10. Seroprevalence trends of antibodies to human immunodeficiency virus among blood donors using routine screening assays and annual donation records for temporal comparison: a retrospective study
  11. Seroprevalence of antibodies to hepatitis C virus among blood donors using routinely performed serological screening and repeat reactive testing protocols as laboratory reference standards: a retrospective study
  12. Seroprevalence of syphilis screening reactivity among blood donors using routine blood bank serology and confirmatory records where available as reference assessment: a retrospective study
  13. Prevalence of malaria screening positivity among blood donors in an endemic region using routine blood bank testing and donor records as reference assessment: a retrospective cross-sectional study
  14. Frequency of multiple transfusion-transmitted infection marker reactivity among blood donors using routine serological screening results for characterisation of co-reactive patterns: a retrospective study
  15. Comparison of transfusion-transmitted infection marker prevalence between first-time and repeat blood donors using routine blood bank screening results as outcome measures: a retrospective cross-sectional study
  16. Prevalence of ABO and Rh blood groups among blood donors using routine forward and reverse grouping as reference classification: a retrospective record-based study
  17. Frequency and causes of ABO blood group discrepancies among donor and patient samples using repeat forward and reverse grouping as reference resolution methods: a retrospective laboratory study
  18. Agreement between conventional tube and gel-card blood grouping methods where both are routinely used, using resolved blood group as reference standard: a method-comparison study
  19. Agreement between forward and reverse ABO grouping among routine donor samples using repeat testing for discrepant cases as reference assessment: a laboratory agreement study
  20. Frequency of Rh negative blood groups among donors and component recipients using routine serological typing as reference classification: a retrospective study
  21. Prevalence of weak D reactions among samples undergoing routine extended Rh typing using confirmatory serological testing as reference assessment: a retrospective laboratory study
  22. Frequency and specificity of unexpected red cell antibodies detected during pretransfusion testing using routine antibody screening and identification methods as reference classification: a retrospective study
  23. Prevalence of positive indirect antiglobulin tests among multitransfused patients using routine antibody screening and identification as diagnostic reference methods: a cross-sectional study
  24. Frequency of positive direct antiglobulin tests among patients investigated for haemolysis using routine clinical diagnosis and peripheral smear findings as comparators: a retrospective cross-sectional study
  25. Correlation of direct antiglobulin test strength with haemoglobin concentration and biochemical haemolysis parameters in patients evaluated for immune haemolytic anaemia: a cross-sectional study
  26. Frequency and causes of incompatible crossmatches among patients requiring transfusion using antibody screening and resolved serological investigation as reference classification: a retrospective laboratory study
  27. Audit of crossmatch-to-transfusion ratio among surgical patients using blood component issue records and institutional utilisation targets as quality outcome measures: a retrospective study
  28. Audit of blood component utilisation in elective surgical procedures using actual transfusion against reserved units as reference for appropriateness of ordering practices: a retrospective study
  29. Proportion of single-unit red cell transfusions among stable adult inpatients using transfusion request indications and post-transfusion haemoglobin records as utilisation outcomes: a retrospective audit
  30. Appropriateness of packed red cell transfusion requests in adults using institutional haemoglobin thresholds and documented clinical indications as reference criteria: a retrospective audit
  31. Appropriateness of platelet transfusion requests using pretransfusion platelet count and documented clinical indication against institutional transfusion guidelines as reference standards: a retrospective audit
  32. Appropriateness of fresh frozen plasma transfusion requests using coagulation test results and documented bleeding indications against institutional guidelines as reference standards: a retrospective audit
  33. Correlation of pretransfusion haemoglobin with post-transfusion haemoglobin increment after one packed red cell unit in stable adults using routine laboratory measurements as outcome assessment: a retrospective study
  34. Correlation of platelet dose with one-hour or next-routine-count platelet increment where available in thrombocytopenic patients receiving routine platelet transfusion: a retrospective observational study
  35. Frequency and types of acute transfusion reactions using haemovigilance records and standard reaction definitions as reference classification: a retrospective record-based study
  36. Clinical and laboratory profile of febrile non-haemolytic transfusion reactions using routine reaction workup and haemovigilance classification as reference assessment: a retrospective study
  37. Clinical and laboratory profile of allergic transfusion reactions using haemovigilance definitions and documented transfusion reaction workup as reference assessment: a retrospective study
  38. Frequency of transfusion-associated haemolytic reactions among reported events using direct antiglobulin testing, repeat grouping and routine biochemical assessment as reference investigations: a retrospective study
  39. Audit of bedside transfusion reaction reporting completeness using haemovigilance forms against predefined documentation standards as quality outcome measures: a retrospective study
  40. Turnaround time of emergency blood component issue using blood bank timestamps against institutional emergency-release targets as reference standards: a retrospective audit
  41. Frequency and causes of blood component wastage using component disposition records and predefined avoidable-wastage categories as outcome measures: a retrospective blood bank audit
  42. Comparative wastage rates of red cell, platelet and plasma components using expiry, storage and return records for classification of preventable causes: a retrospective study
  43. Correlation of platelet component wastage with monthly demand and expiry patterns using routine inventory records as service utilisation outcomes: a retrospective study
  44. Audit of cold-chain breaches for returned red cell units using documented temperature and return-time criteria against blood bank acceptance standards: a retrospective quality study
  45. Frequency of blood bag discard due to seroreactivity, undercollection, expiry and technical causes using component production records for classification of preventable loss: a retrospective study
  46. Prevalence of low haemoglobin among repeat blood donors using routine pre-donation testing and donation history as comparator for cumulative donation-related iron depletion risk: a cross-sectional study
  47. Association of donation frequency with haemoglobin concentration among repeat blood donors using routine donation records and pre-donation haemoglobin measurements: a retrospective observational study
  48. Audit of informed consent documentation for blood transfusion using patient records against institutional consent requirements as reference standards for compliance: a retrospective quality study
  49. Audit of traceability from blood donation to component issue using blood bank records against predefined documentation standards as outcome measures: a retrospective quality-assurance study
  50. Audit of turnaround time from blood component request to issue across emergency and routine requests using laboratory timestamps against institutional targets as service-performance outcomes: a retrospective study

Lymph Node Pathology and Haematolymphoid Cytology

  1. Diagnostic accuracy of fine needle aspiration cytology in patients with cervical lymphadenopathy using histopathological examination where available as reference standard for classification of benign and malignant lesions: a cross-sectional study
  2. Diagnostic accuracy of fine needle aspiration cytology for tuberculous lymphadenitis in patients with cervical lymphadenopathy using histopathology, Ziehl-Neelsen stain and clinical diagnosis as composite reference standard: a cross-sectional study
  3. Diagnostic yield of Ziehl-Neelsen staining in cytological smears showing granulomatous lymphadenitis using final clinicopathological diagnosis as reference standard for tuberculous lymphadenitis: a cross-sectional study
  4. Correlation of cytomorphological patterns of granulomatous lymphadenitis with Ziehl-Neelsen stain positivity in patients with cervical lymphadenopathy for predicting mycobacterial infection: a cross-sectional study
  5. Diagnostic accuracy of caseous necrosis on fine needle aspiration cytology for tuberculous lymphadenitis using final clinicopathological diagnosis as reference standard: a cross-sectional study
  6. Comparative diagnostic yield of direct smear cytology and cell-block examination in lymph node aspirates using histopathological examination where available as reference standard for malignant lesions: a prospective observational study
  7. Incremental diagnostic yield of cell-block preparation over conventional smears in lymph node aspirates with suspected malignancy using histopathology as reference standard: a cross-sectional study
  8. Diagnostic accuracy of fine needle aspiration cytology for metastatic squamous cell carcinoma in cervical lymph nodes using histopathology of lymph node or primary tumour as reference standard: a cross-sectional study
  9. Diagnostic accuracy of fine needle aspiration cytology for metastatic adenocarcinoma in lymph nodes using histopathological examination as reference standard for metastatic malignancy: a cross-sectional study
  10. Cytohistological correlation of metastatic malignancies in lymph nodes sampled by fine needle aspiration using corresponding biopsy or resection histopathology as reference standard: a retrospective study
  11. Diagnostic accuracy of cytological necrosis with atypical cells for metastatic carcinoma in lymph node aspirates using histopathology as reference standard: a cross-sectional study
  12. Correlation of lymph node cytomorphology with site of primary carcinoma in patients with metastatic nodal disease using histopathological confirmation as comparator: a retrospective cross-sectional study
  13. Diagnostic accuracy of fine needle aspiration cytology for lymphoma among patients with persistent lymphadenopathy using histopathology and routine immunohistochemistry as reference standard: a cross-sectional study
  14. Frequency and causes of false-negative fine needle aspiration cytology in lymphoma using subsequent lymph node biopsy histopathology as reference standard: a retrospective diagnostic audit
  15. Frequency and causes of false-positive fine needle aspiration cytology for lymphoma using subsequent histopathology and routine immunohistochemistry as reference standard: a retrospective audit
  16. Inter-observer agreement in cytological classification of reactive hyperplasia, granulomatous lymphadenitis, metastatic carcinoma and suspected lymphoma using consensus microscopy as reference assessment: an observer-agreement study
  17. Diagnostic accuracy of monomorphic lymphoid population on cytology for lymphoma using histopathology with routine immunohistochemistry as reference standard: a cross-sectional study
  18. Diagnostic accuracy of tingible-body macrophages and polymorphous lymphoid population for reactive lymphadenitis using histopathology or final clinical diagnosis as reference standard: a cross-sectional study
  19. Correlation of lymph node size and anatomical site with cytological diagnosis in patients undergoing routine fine needle aspiration for lymphadenopathy: a cross-sectional observational study
  20. Prevalence of tuberculous lymphadenitis among cervical lymph node aspirates and correlation with age, sex and cytomorphological pattern using final clinicopathological diagnosis as comparator: a retrospective study
  21. Seasonal distribution of tuberculous lymphadenitis diagnosed by lymph node cytology using monthly laboratory records and Ziehl-Neelsen positivity as secondary outcome measures: a retrospective study
  22. Diagnostic yield of repeat fine needle aspiration in initially inadequate lymph node cytology samples using final cytological or histological diagnosis as reference outcome: a retrospective study
  23. Audit of adequacy rates in lymph node fine needle aspiration cytology using predefined cellularity criteria and final diagnostic category as quality outcomes: a retrospective laboratory study
  24. Correlation of aspirate gross appearance with cytological diagnosis in lymph node fine needle aspiration samples using final cytomorphological classification as reference assessment: a prospective observational study
  25. Diagnostic accuracy of pus-like aspirate for suppurative or tuberculous lymphadenitis using microscopy, Ziehl-Neelsen stain and final diagnosis as reference standards: a cross-sectional study
  26. Diagnostic yield of periodic acid-Schiff stain in lymph node aspirates with suspected fungal infection using final clinicopathological diagnosis as reference standard: a retrospective archival study
  27. Frequency and cytomorphological features of fungal lymphadenitis among granulomatous lymph node aspirates using periodic acid-Schiff staining and final clinical diagnosis as reference classification: an archival study
  28. Cytohistological correlation of paediatric lymphadenopathy using fine needle aspiration cytology and corresponding biopsy histopathology for assessment of diagnostic concordance: a retrospective study
  29. Prevalence and cytological spectrum of paediatric cervical lymphadenopathy using routine fine needle aspiration specimens and final clinical or histological diagnosis as comparators: a retrospective study
  30. Diagnostic accuracy of fine needle aspiration cytology for suppurative lymphadenitis using microbiological or clinical diagnosis where available as reference standard: a cross-sectional study
  31. Correlation of neutrophilic background and necrosis on lymph node cytology with suppurative clinical diagnosis using routine culture where available as comparator: a cross-sectional study
  32. Diagnostic accuracy of fine needle aspiration cytology for Kikuchi disease where suspected using excision biopsy histopathology as reference standard for necrotising lymphadenitis: a retrospective study
  33. Morphological features associated with Kikuchi disease in lymph node cytology compared with histopathological diagnosis in excised nodes: a retrospective case-control study
  34. Diagnostic accuracy of fine needle aspiration cytology for metastatic papillary thyroid carcinoma in cervical lymph nodes using histopathology of thyroid or lymph node as reference standard: a retrospective study
  35. Diagnostic accuracy of fine needle aspiration cytology for metastatic breast carcinoma in axillary lymph nodes using nodal histopathology as reference standard: a cross-sectional study
  36. Correlation of axillary lymph node cytology with final nodal histopathology in patients with breast carcinoma undergoing routine preoperative nodal assessment: a prospective observational study
  37. Diagnostic accuracy of fine needle aspiration cytology for metastatic oral squamous cell carcinoma in cervical lymph nodes using nodal histopathology as reference standard: a cross-sectional study
  38. Correlation of extranodal tumour features on cytology with histological extranodal extension in metastatic cervical squamous cell carcinoma where corresponding resection is available: a retrospective study
  39. Diagnostic contribution of cell-block immunohistochemistry in cytologically indeterminate malignant lymph node aspirates using subsequent biopsy diagnosis as reference standard: an archival cross-sectional study
  40. Agreement between conventional smear and cell-block classification in malignant lymph node aspirates using histopathology as reference standard for tumour category: a comparative cross-sectional study
  41. Diagnostic accuracy of lymphoglandular bodies on cytological smears for lymphoid neoplasms using histopathology with routine immunohistochemistry as reference standard: a retrospective study
  42. Correlation of cytological mitotic activity with histological proliferation category in lymphomas using excision biopsy and routinely performed Ki-67 immunohistochemistry as comparators: an archival study
  43. Agreement between cytological and histological assessment of necrosis in metastatic lymph node malignancies using paired fine needle aspiration and biopsy specimens: a retrospective study
  44. Diagnostic accuracy of fine needle aspiration cytology in supraclavicular lymphadenopathy using histopathology or clinically confirmed primary malignancy as reference standard: a cross-sectional study
  45. Spectrum and diagnostic yield of fine needle aspiration cytology in supraclavicular lymph nodes using final clinical or histopathological diagnosis as comparator: a retrospective study
  46. Diagnostic accuracy of fine needle aspiration cytology in inguinal lymphadenopathy using biopsy histopathology where available as reference standard for benign and malignant disease: a cross-sectional study
  47. Prevalence of malignant diagnoses among elderly patients undergoing lymph node fine needle aspiration using final cytological and histological records for classification: a retrospective study
  48. Correlation of necrosis percentage on cytology with Ziehl-Neelsen positivity in granulomatous lymphadenitis using final tuberculous diagnosis as comparator: a cross-sectional study
  49. Inter-observer agreement in grading granulomas, necrosis and giant cells in cytologically diagnosed tuberculous lymphadenitis using consensus microscopy as reference assessment: an observer-agreement study
  50. Audit of lymph node cytology reporting turnaround time and non-diagnostic rate using laboratory information timestamps and predefined quality targets as service-performance outcomes: a retrospective study

Thyroid Pathology and Cytopathology

  1. Diagnostic accuracy of fine needle aspiration cytology reported by the Bethesda System for Reporting Thyroid Cytopathology against histopathological examination of resected specimens for detection of malignancy in adults with thyroid nodules: a cross-sectional study
  2. Risk of malignancy for each Bethesda System for Reporting Thyroid Cytopathology category in patients with thyroid nodules using resection histopathology as reference standard: a retrospective cross-sectional study
  3. Cytohistological correlation of thyroid nodules reported by the Bethesda System for Reporting Thyroid Cytopathology using corresponding surgical histopathology for assessment of categorical concordance: a retrospective study
  4. Diagnostic accuracy of the Bethesda System for Reporting Thyroid Cytopathology category six for thyroid malignancy using resection histopathology as reference standard: a retrospective study
  5. Diagnostic accuracy of the Bethesda System for Reporting Thyroid Cytopathology category five for thyroid malignancy using resection histopathology as reference standard: a retrospective study
  6. Malignancy risk of the Bethesda System for Reporting Thyroid Cytopathology category three in surgically followed thyroid nodules using resection histopathology as reference standard: a retrospective study
  7. Malignancy risk of the Bethesda System for Reporting Thyroid Cytopathology category four in surgically followed thyroid nodules using resection histopathology as reference standard: a retrospective study
  8. Diagnostic accuracy of papillary nuclear features on thyroid fine needle aspiration cytology for papillary thyroid carcinoma using resection histopathology as reference standard: a cross-sectional study
  9. Inter-observer agreement in identifying nuclear grooves, inclusions, chromatin clearing and overlap on thyroid cytology using consensus review and histopathological diagnosis as comparators: an observer-agreement study
  10. Diagnostic accuracy of nuclear inclusions on thyroid cytology for papillary thyroid carcinoma using resection histopathology as reference standard: a retrospective study
  11. Diagnostic accuracy of nuclear grooves on thyroid cytology for papillary thyroid carcinoma using resection histopathology as reference standard: a retrospective study
  12. Correlation of cytological papillary architecture with histological papillary thyroid carcinoma in thyroid nodules using resection specimens as reference assessment: a retrospective study
  13. Diagnostic accuracy of colloid quantity and follicular architecture for benign follicular nodules using resection histopathology as reference standard: a retrospective cross-sectional study
  14. Diagnostic accuracy of thyroid fine needle aspiration cytology for Hashimoto thyroiditis using histopathology or integrated clinical and serological diagnosis as reference standard: a cross-sectional study
  15. Correlation of lymphocytic infiltration grading on thyroid cytology with histological lymphocytic thyroiditis in paired specimens using resection histopathology as reference assessment: a retrospective study
  16. Diagnostic accuracy of Hürthle cell predominance on thyroid cytology for Hürthle cell neoplasm using resection histopathology as reference standard: a retrospective study
  17. Frequency and histological outcomes of Hürthle cell-rich thyroid aspirates classified by the Bethesda System for Reporting Thyroid Cytopathology using resection diagnosis as comparator: a retrospective study
  18. Diagnostic accuracy of thyroid fine needle aspiration cytology for medullary thyroid carcinoma using histopathology and routine immunohistochemistry as reference standard: a retrospective study
  19. Cytomorphological features distinguishing medullary thyroid carcinoma from papillary thyroid carcinoma using histopathologically confirmed cases as reference groups: a retrospective case-control study
  20. Diagnostic accuracy of amyloid-like material on thyroid cytology for medullary thyroid carcinoma using Congo red staining and histopathology as reference standards: an archival study
  21. Diagnostic accuracy of fine needle aspiration cytology for anaplastic thyroid carcinoma using histopathological examination as reference standard: a retrospective study
  22. Cytomorphological features distinguishing anaplastic thyroid carcinoma from metastatic carcinoma in thyroid aspirates using histopathology and basic immunohistochemistry as reference classification: a retrospective study
  23. Diagnostic accuracy of fine needle aspiration cytology for thyroid lymphoma using histopathology with routine immunohistochemistry as reference standard: a retrospective study
  24. Frequency and causes of non-diagnostic thyroid fine needle aspiration cytology using the Bethesda System for Reporting Thyroid Cytopathology and repeat cytology or histology as outcome measures: a retrospective audit
  25. Diagnostic yield of repeat fine needle aspiration in initially non-diagnostic thyroid nodules using final cytological or histological diagnosis as reference outcome: a retrospective study
  26. Diagnostic yield of repeat fine needle aspiration in thyroid nodules initially categorised as atypia of undetermined significance using subsequent cytology or histopathology as reference assessment: a retrospective study
  27. Inter-observer agreement in categorising thyroid fine needle aspiration smears by the Bethesda System for Reporting Thyroid Cytopathology using consensus classification as reference assessment: an observer-agreement study
  28. Intra-observer reproducibility of the Bethesda System for Reporting Thyroid Cytopathology in selected indeterminate thyroid aspirates using blinded repeat review as outcome measure: an archival agreement study
  29. Correlation of thyroid nodule size with Bethesda System for Reporting Thyroid Cytopathology category and histological malignancy in resected nodules: a retrospective observational study
  30. Correlation of patient age with malignancy risk within indeterminate Bethesda System for Reporting Thyroid Cytopathology categories using resection histopathology as reference standard: a retrospective study
  31. Correlation of sex with malignancy risk across Bethesda System for Reporting Thyroid Cytopathology categories using histopathological outcome in surgically managed thyroid nodules: a retrospective study
  32. Diagnostic accuracy of cystic background on thyroid fine needle aspiration cytology for benign cystic nodules using resection or repeat cytology as reference assessment: a cross-sectional study
  33. Frequency and histological outcomes of cystic thyroid lesions sampled by fine needle aspiration using corresponding surgical pathology where available as reference classification: a retrospective study
  34. Diagnostic accuracy of psammoma bodies on thyroid cytology for papillary thyroid carcinoma using resection histopathology as reference standard: a retrospective study
  35. Diagnostic accuracy of multinucleated giant cells on thyroid cytology for papillary thyroid carcinoma using histopathological examination as reference standard: a retrospective study
  36. Diagnostic accuracy of thick ropy colloid for benign colloid nodules on thyroid cytology using resection histopathology or stable repeat cytology as reference assessment: a cross-sectional study
  37. Cytohistological correlation of follicular-patterned thyroid lesions using Bethesda System for Reporting Thyroid Cytopathology categories and resection histopathology for final classification: a retrospective study
  38. Frequency of follicular adenoma and follicular carcinoma among Bethesda System for Reporting Thyroid Cytopathology category four nodules using resection histopathology as reference classification: a retrospective study
  39. Correlation of capsular and vascular invasion on histopathology with preoperative cytological features in follicular thyroid neoplasms using paired specimens: a retrospective study
  40. Histopathological spectrum of resected multinodular goitre specimens using fine needle aspiration diagnosis where available as comparator for detection of incidental malignancy: a retrospective study
  41. Prevalence of incidental papillary microcarcinoma in thyroidectomy specimens for benign preoperative diagnoses using complete histopathological examination as reference assessment: an archival study
  42. Correlation of tumour size with lymphovascular invasion in papillary thyroid carcinoma using routine histopathological sections and nodal status as comparator: an archival cross-sectional study
  43. Correlation of papillary thyroid carcinoma histological subtype with cervical lymph node metastasis using resection and nodal histopathology as outcome assessment: a retrospective study
  44. Correlation of extrathyroidal extension with lymph node metastasis in papillary thyroid carcinoma using thyroidectomy and neck dissection histopathology as reference assessment: a retrospective study
  45. Association of lymphovascular invasion with lymph node metastasis in papillary thyroid carcinoma using routine histopathological examination as outcome measurement: an archival cross-sectional study
  46. Correlation of tumour multifocality with lymph node metastasis in papillary thyroid carcinoma using complete thyroidectomy histopathology and nodal examination: a retrospective study
  47. Agreement between cytological and histological diagnosis of Hashimoto thyroiditis in paired thyroid specimens using resection histopathology as reference standard: a retrospective agreement study
  48. Diagnostic contribution of cell-block preparation in thyroid fine needle aspiration specimens with suspected malignancy using resection histopathology as reference standard: a prospective observational study
  49. Audit of adequacy and reporting distribution of thyroid fine needle aspiration cytology using the Bethesda System for Reporting Thyroid Cytopathology and predefined laboratory quality indicators: a retrospective study
  50. Audit of turnaround time for thyroid fine needle aspiration cytology using laboratory information timestamps and predefined institutional targets with non-diagnostic rate as secondary quality outcome: a retrospective study

Breast Pathology and Cytopathology

  1. Diagnostic accuracy of breast fine needle aspiration cytology reported by the International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology using histopathology as reference standard for malignancy: a cross-sectional study
  2. Risk of malignancy for each International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology category using surgical histopathology as reference standard: a retrospective study
  3. Cytohistological correlation of breast lesions classified by the International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology using corresponding histopathology: a retrospective study
  4. Inter-observer agreement in categorising breast fine needle aspiration cytology by the International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology using consensus diagnosis as reference: an archival study
  5. Diagnostic accuracy of breast fine needle aspiration cytology for fibroadenoma using histopathology or concordant clinical follow-up within six months as reference assessment: a cross-sectional study
  6. Diagnostic accuracy of breast fine needle aspiration cytology for invasive carcinoma using core biopsy or resection histopathology as reference standard: a hospital-based cross-sectional study
  7. Diagnostic accuracy of cytological nuclear atypia, discohesion and necrosis for invasive breast carcinoma using histopathological diagnosis as reference standard: a retrospective study
  8. Diagnostic accuracy of breast fine needle aspiration cytology for proliferative fibrocystic lesions using histopathology as reference standard in surgically sampled cases: a retrospective study
  9. Diagnostic contribution of cell-block preparation in malignant breast aspirates using core biopsy or resection histopathology as reference standard for tumour classification: a prospective observational study
  10. Agreement between conventional cytological smears and cell-block sections in breast aspirates with suspected malignancy using histopathology as reference standard: a comparative cross-sectional study
  11. Correlation of cytological tumour grade with Nottingham modification of the Bloom-Richardson grading system on histopathology in invasive breast carcinoma: a retrospective cross-sectional study
  12. Inter-observer agreement in Nottingham modification of the Bloom-Richardson grading system among invasive breast carcinomas using consensus histological grade as reference assessment: an archival study
  13. Correlation of tubule formation, nuclear pleomorphism and mitotic score with final Nottingham modification of the Bloom-Richardson grading system in invasive breast carcinoma: an archival correlation study
  14. Correlation of Nottingham modification of the Bloom-Richardson grading system with oestrogen receptor expression in invasive breast carcinoma using routine immunohistochemistry as outcome assessment: an archival study
  15. Correlation of Nottingham modification of the Bloom-Richardson grading system with progesterone receptor expression in invasive breast carcinoma using routine immunohistochemistry as outcome assessment: an archival study
  16. Correlation of Nottingham modification of the Bloom-Richardson grading system with human epidermal growth factor receptor 2 expression in invasive breast carcinoma using routine immunohistochemistry as outcome assessment: an archival study
  17. Correlation of Nottingham modification of the Bloom-Richardson grading system with Ki-67 proliferation index in invasive breast carcinoma using routinely performed immunohistochemistry as comparator: an archival study
  18. Association of lymphovascular invasion with axillary lymph node metastasis in invasive breast carcinoma using resection histopathology as reference assessment: a retrospective cross-sectional study
  19. Correlation of tumour size with axillary lymph node metastasis in invasive breast carcinoma using mastectomy or breast-conserving surgery specimens with nodal histopathology: a retrospective study
  20. Correlation of histological grade with axillary lymph node metastasis in invasive breast carcinoma using Nottingham modification of the Bloom-Richardson grading system and nodal histopathology: a retrospective study
  21. Association of perineural invasion with tumour grade and nodal metastasis in invasive breast carcinoma using routine histopathological examination as outcome assessment: an archival study
  22. Frequency and clinicopathological correlates of lymphovascular invasion in invasive breast carcinoma using haematoxylin and eosin sections and nodal status as comparator: an archival cross-sectional study
  23. Correlation of tumour necrosis with Nottingham modification of the Bloom-Richardson grading system in invasive breast carcinoma using routine histopathology: an archival study
  24. Correlation of tumour-infiltrating lymphocyte density assessed on routine haematoxylin and eosin sections with histological grade in invasive breast carcinoma: an archival cross-sectional study
  25. Inter-observer agreement in semiquantitative assessment of tumour-infiltrating lymphocytes in invasive breast carcinoma using consensus microscopy as reference assessment: an archival agreement study
  26. Correlation of tumour-infiltrating lymphocyte density with oestrogen receptor, progesterone receptor and human epidermal growth factor receptor 2 status using routine immunohistochemistry: an archival study
  27. Histopathological distribution of invasive breast carcinoma subtypes using World Health Organization Classification of Tumours Fifth Edition criteria and routine immunohistochemical profile as comparator: an archival study
  28. Correlation of histological subtype with Nottingham modification of the Bloom-Richardson grading system in invasive breast carcinoma using routine resection specimens: an archival study
  29. Frequency of ductal carcinoma in situ associated with invasive breast carcinoma and correlation with tumour grade using routine resection histopathology: a retrospective study
  30. Correlation of extensive in situ component with surgical margin involvement in breast-conserving excision specimens using routine histopathological margin assessment: a retrospective study
  31. Agreement between gross tumour size and microscopic tumour size in breast carcinoma resection specimens using histopathological measurement as reference standard: a specimen-based comparison study
  32. Correlation of gross tumour size with pathological tumour category in invasive breast carcinoma using microscopic measurement as reference assessment: a retrospective study
  33. Frequency and causes of positive surgical margins in breast-conserving specimens using inked histopathological margin assessment and re-excision findings where available as comparator: a retrospective study
  34. Correlation of fine needle aspiration cytology of axillary lymph nodes with final nodal histopathology in patients with breast carcinoma undergoing surgery: a prospective observational study
  35. Diagnostic accuracy of axillary lymph node fine needle aspiration cytology for metastatic breast carcinoma using nodal histopathology as reference standard: a cross-sectional study
  36. Diagnostic accuracy of cytological features of apocrine change in breast aspirates using histopathology as reference standard for benign apocrine lesions: a retrospective study
  37. Cytological features distinguishing fibroadenoma from phyllodes tumour in breast fine needle aspiration specimens using resection histopathology as reference classification: a retrospective case-control study
  38. Diagnostic accuracy of stromal hypercellularity and leaf-like fragments on breast cytology for phyllodes tumour using histopathology as reference standard: a retrospective study
  39. Correlation of histological grade of phyllodes tumour with mitotic count, stromal cellularity and margin status using World Health Organization Classification of Tumours Fifth Edition criteria: an archival study
  40. Inter-observer agreement in classifying phyllodes tumours as benign, borderline or malignant using World Health Organization Classification of Tumours Fifth Edition criteria and consensus diagnosis as reference: an archival study
  41. Correlation of mitotic count with histological category in phyllodes tumour using resection histopathology as reference assessment: an archival study
  42. Diagnostic accuracy of breast fine needle aspiration cytology for granulomatous mastitis using core biopsy histopathology and special stains where performed as reference standard: a cross-sectional study
  43. Correlation of granulomatous inflammation pattern in breast cytology with histological granulomatous mastitis using paired cytology and biopsy specimens: a retrospective study
  44. Diagnostic yield of Ziehl-Neelsen and periodic acid-Schiff stains in granulomatous mastitis biopsies using final clinicopathological diagnosis as reference standard for infectious causes: an archival study
  45. Frequency of male breast lesions on fine needle aspiration cytology and correlation with histopathological diagnosis where available for classification of gynaecomastia and malignancy: a retrospective study
  46. Diagnostic accuracy of fine needle aspiration cytology for gynaecomastia using histopathology or concordant clinical diagnosis as reference assessment: a cross-sectional study
  47. Diagnostic accuracy of fine needle aspiration cytology for male breast carcinoma using histopathology as reference standard: a retrospective study
  48. Audit of breast fine needle aspiration adequacy using predefined cytological criteria and International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology categories as quality outcomes: a retrospective study
  49. Audit of cytohistological discordance in breast lesions using paired fine needle aspiration and surgical pathology diagnoses for identification of major causes of diagnostic error: a retrospective quality study
  50. Audit of breast pathology reporting turnaround time using laboratory information timestamps and predefined institutional targets with immunohistochemistry completion time as secondary outcome: a retrospective study

Gynaecological Pathology and Cervical Cytology

  1. Prevalence of epithelial cell abnormalities in routine cervical cytology reported by the Bethesda System for Reporting Cervical Cytology using histopathology where available as reference assessment: a retrospective screening study
  2. Cytohistological correlation of cervical epithelial abnormalities reported by the Bethesda System for Reporting Cervical Cytology using cervical biopsy histopathology as reference standard: a retrospective study
  3. Diagnostic accuracy of high-grade squamous intraepithelial lesion on cervical cytology for histological high-grade cervical intraepithelial neoplasia using biopsy as reference standard: a cross-sectional study
  4. Diagnostic accuracy of atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion, for histological high-grade cervical intraepithelial neoplasia using biopsy as reference standard: a retrospective study
  5. Histological outcomes of atypical squamous cells of undetermined significance on cervical cytology using biopsy where performed as reference assessment: a retrospective study
  6. Histological outcomes of low-grade squamous intraepithelial lesion on cervical cytology using cervical biopsy as reference assessment: a retrospective study
  7. Risk of significant histological cervical lesion across Bethesda System for Reporting Cervical Cytology categories using biopsy histopathology as reference standard: a retrospective cross-sectional study
  8. Inter-observer agreement in reporting cervical cytology by the Bethesda System for Reporting Cervical Cytology using consensus microscopy as reference assessment: an archival observer-agreement study
  9. Inter-observer agreement in distinguishing reactive squamous atypia from squamous intraepithelial lesions on cervical cytology using histopathological outcome where available as comparator: an archival study
  10. Frequency and cytological correlates of unsatisfactory cervical smears using Bethesda System for Reporting Cervical Cytology adequacy criteria and repeat smear outcome as reference assessment: a retrospective audit
  11. Diagnostic yield of repeat cervical cytology after an unsatisfactory initial smear using subsequent satisfactory cytology or biopsy as reference outcome: a retrospective study
  12. Association of transformation-zone component presence with detection of epithelial abnormalities in cervical cytology using Bethesda System for Reporting Cervical Cytology reporting categories as outcome measures: a retrospective study
  13. Correlation of inflammatory background severity with epithelial cell abnormality detection on cervical cytology using final cytological category as comparator: a cross-sectional study
  14. Prevalence of specific infectious cytomorphological changes in cervical smears using routine microscopy and clinical or microbiological diagnosis where available as reference assessment: a retrospective study
  15. Diagnostic accuracy of Candida morphology on cervical cytology using routine microbiological findings where available as reference standard for candidal infection: a cross-sectional study
  16. Diagnostic accuracy of bacterial vaginosis-associated clue cells on cervical cytology using routine clinical or microbiological diagnosis as reference standard: a cross-sectional study
  17. Correlation of age and menopausal status with cervical cytological epithelial abnormalities using Bethesda System for Reporting Cervical Cytology categories as outcome measures: a retrospective study
  18. Prevalence of atrophic changes and associated atypia in cervical smears from postmenopausal women using biopsy where available to assess significant lesions: a retrospective study
  19. Correlation of cervical cytology category with histological lesion severity in women undergoing colposcopy-directed biopsy using biopsy diagnosis as reference standard: a retrospective cross-sectional study
  20. Audit of turnaround time and reporting completeness for cervical cytology using laboratory timestamps and Bethesda System for Reporting Cervical Cytology mandatory elements as quality standards: a retrospective study
  21. Histopathological spectrum of endometrial biopsies from women with abnormal uterine bleeding using age and menopausal status as clinical comparators: a retrospective cross-sectional study
  22. Correlation of endometrial histological pattern with age in women undergoing biopsy for abnormal uterine bleeding using routine histopathology as outcome assessment: a retrospective study
  23. Prevalence of endometrial hyperplasia without atypia, atypical hyperplasia and carcinoma among women with abnormal uterine bleeding using biopsy histopathology as reference diagnosis: a retrospective study
  24. Correlation of endometrial thickness documented by ultrasonography with biopsy histopathology in women with abnormal uterine bleeding for prediction of hyperplasia or carcinoma: a retrospective diagnostic study
  25. Diagnostic accuracy of ultrasonographic endometrial thickness for significant endometrial pathology in postmenopausal bleeding using endometrial biopsy histopathology as reference standard: a retrospective study
  26. Correlation of histological endometrial pattern with menstrual status in perimenopausal women with abnormal uterine bleeding using routine biopsy specimens: a retrospective observational study
  27. Prevalence of disordered proliferative endometrium among women with abnormal uterine bleeding using histopathological examination and age category as comparative parameter: a retrospective study
  28. Frequency of endometrial polyps in women with abnormal uterine bleeding using biopsy or hysterectomy histopathology as reference diagnosis and ultrasonography where available as comparator: a retrospective study
  29. Diagnostic accuracy of endometrial biopsy for hyperplasia and carcinoma using subsequent hysterectomy histopathology as reference standard in women undergoing definitive surgery: a retrospective study
  30. Agreement between preoperative endometrial biopsy and hysterectomy diagnosis in endometrial hyperplasia using hysterectomy histopathology as reference assessment: a retrospective agreement study
  31. Agreement between endometrial biopsy tumour grade and hysterectomy tumour grade in endometrioid carcinoma using final resection histopathology as reference standard: a retrospective study
  32. Correlation of myometrial invasion depth with tumour grade in endometrioid carcinoma using hysterectomy histopathology as outcome assessment: an archival cross-sectional study
  33. Association of lymphovascular invasion with myometrial invasion depth in endometrioid carcinoma using routine hysterectomy histopathology as reference assessment: an archival study
  34. Correlation of cervical stromal involvement with myometrial invasion and tumour grade in endometrial carcinoma using hysterectomy histopathology: a retrospective study
  35. Histopathological spectrum of hysterectomy specimens for abnormal uterine bleeding using preoperative endometrial biopsy diagnosis where available as comparator: a retrospective study
  36. Agreement between preoperative endometrial biopsy and hysterectomy histopathology for non-neoplastic and neoplastic endometrial lesions in women with abnormal uterine bleeding: a retrospective study
  37. Histopathological spectrum of ovarian tumours using World Health Organization Classification of Tumours Fifth Edition criteria and age distribution as clinicopathological comparator: an archival cross-sectional study
  38. Correlation of gross morphology with histological category of ovarian tumours using resection histopathology as reference standard: a retrospective specimen-based study
  39. Diagnostic accuracy of intraoperative gross assessment recorded for ovarian masses using final histopathology as reference standard for benign versus malignant classification: a retrospective study
  40. Correlation of ovarian tumour size with benign, borderline and malignant histological categories using final resection histopathology as reference assessment: an archival study
  41. Histopathological spectrum of epithelial ovarian tumours using World Health Organization Classification of Tumours Fifth Edition criteria and menopausal status as comparator: an archival study
  42. Histopathological spectrum of germ cell tumours of the ovary using World Health Organization Classification of Tumours Fifth Edition criteria and age as clinical comparator: an archival study
  43. Correlation of mitotic activity with histological category in selected ovarian sex cord-stromal tumours using resection histopathology and Ki-67 where routinely performed as comparators: an archival study
  44. Diagnostic accuracy of peritoneal fluid cytology for detecting malignant cells in ovarian carcinoma using peritoneal or omental histopathology as reference standard: a retrospective study
  45. Correlation of peritoneal cytology positivity with omental metastasis in epithelial ovarian carcinoma using staging histopathology as reference assessment: a retrospective study
  46. Histopathological spectrum of cervical biopsies in women with abnormal cervical cytology using Bethesda System for Reporting Cervical Cytology category as comparator: a retrospective study
  47. Correlation of cervical intraepithelial neoplasia grade with p16 immunohistochemistry where routinely performed using consensus histopathological grade as reference assessment: an archival study
  48. Inter-observer agreement in grading cervical intraepithelial neoplasia on haematoxylin and eosin sections using consensus microscopy and p16 immunohistochemistry where available as comparators: an archival study
  49. Correlation of tumour differentiation with lymphovascular invasion in cervical squamous cell carcinoma using routine hysterectomy or biopsy histopathology as outcome assessment: an archival study
  50. Audit of gynaecological biopsy and hysterectomy pathology turnaround time using laboratory timestamps and predefined institutional targets with add-on immunohistochemistry as secondary outcome: a retrospective study

Gastrointestinal Pathology

  1. Prevalence of Helicobacter pylori in gastric biopsies using routine haematoxylin and eosin morphology with special stain where performed as reference assessment: an archival cross-sectional study
  2. Diagnostic accuracy of haematoxylin and eosin examination for Helicobacter pylori in gastric biopsies using routinely performed special stain as reference standard: an archival study
  3. Correlation of Helicobacter pylori density with chronic inflammation severity in gastric biopsies using routine histological grading as outcome assessment: an archival cross-sectional study
  4. Correlation of Helicobacter pylori presence with neutrophilic activity in chronic gastritis using gastric biopsy histopathology as reference assessment: an archival study
  5. Correlation of Helicobacter pylori infection with intestinal metaplasia in gastric biopsies using routine histopathology and special stain where available as diagnostic comparator: an archival study
  6. Inter-observer agreement in grading chronic inflammation, activity, atrophy and intestinal metaplasia in gastric biopsies using consensus microscopy as reference assessment: an archival study
  7. Prevalence of gastric intestinal metaplasia among adults undergoing endoscopic biopsy using routine histopathology and age as clinicopathological comparator: a retrospective study
  8. Correlation of gastric intestinal metaplasia with Helicobacter pylori status using routine histopathology and special stains where performed as comparator: an archival cross-sectional study
  9. Histopathological spectrum of gastric biopsies from dyspeptic adults using endoscopic findings as clinical comparator for inflammatory, premalignant and malignant lesions: a retrospective study
  10. Agreement between endoscopic impression and gastric biopsy histopathology for gastritis, ulcer and malignancy using histopathology as reference standard: a retrospective diagnostic study
  11. Diagnostic accuracy of endoscopic suspicion of gastric carcinoma using biopsy histopathology as reference standard for malignancy: a retrospective cross-sectional study
  12. Correlation of gastric carcinoma histological type with tumour location using World Health Organization Classification of Tumours Fifth Edition criteria and resection specimens: an archival study
  13. Correlation of gastric carcinoma grade with lymph node metastasis using gastrectomy histopathology and nodal examination as outcome assessment: a retrospective study
  14. Association of lymphovascular invasion with lymph node metastasis in gastric adenocarcinoma using routine resection histopathology as reference assessment: an archival study
  15. Association of perineural invasion with lymph node metastasis in gastric adenocarcinoma using routine gastrectomy histopathology as outcome assessment: an archival study
  16. Correlation of depth of invasion with lymph node metastasis in gastric carcinoma using resection histopathology as reference assessment: a retrospective cross-sectional study
  17. Correlation of tumour differentiation with depth of invasion in gastric adenocarcinoma using gastrectomy histopathology: an archival cross-sectional study
  18. Histopathological spectrum of oesophageal biopsies using endoscopic impression as comparator for inflammatory, dysplastic and malignant lesions: a retrospective study
  19. Diagnostic accuracy of endoscopic suspicion for oesophageal carcinoma using biopsy histopathology as reference standard: a retrospective study
  20. Correlation of histological grade with depth of invasion in oesophageal squamous cell carcinoma using resection specimens as outcome assessment: an archival study
  21. Association of lymphovascular invasion with lymph node metastasis in oesophageal squamous cell carcinoma using resection and nodal histopathology as reference assessment: an archival study
  22. Association of perineural invasion with lymph node metastasis in oesophageal squamous cell carcinoma using routine resection histopathology: an archival study
  23. Correlation of tumour budding assessed on haematoxylin and eosin sections with lymph node metastasis in colorectal adenocarcinoma using resection histopathology: an archival cross-sectional study
  24. Inter-observer agreement in tumour budding assessment in colorectal adenocarcinoma using consensus microscopy as reference classification: an archival observer-agreement study
  25. Correlation of tumour grade with lymph node metastasis in colorectal adenocarcinoma using resection histopathology and nodal examination: a retrospective study
  26. Association of lymphovascular invasion with nodal metastasis in colorectal adenocarcinoma using routine resection histopathology as outcome assessment: an archival study
  27. Association of perineural invasion with nodal metastasis in colorectal adenocarcinoma using routine resection histopathology as outcome assessment: an archival study
  28. Correlation of depth of bowel-wall invasion with lymph node metastasis in colorectal adenocarcinoma using resection histopathology: a retrospective cross-sectional study
  29. Correlation of tumour necrosis with histological grade in colorectal adenocarcinoma using routine haematoxylin and eosin sections: an archival study
  30. Correlation of tumour-infiltrating lymphocyte density with histological grade in colorectal adenocarcinoma using routine haematoxylin and eosin sections: an archival study
  31. Inter-observer agreement in semiquantitative tumour-infiltrating lymphocyte assessment in colorectal carcinoma using consensus microscopy as reference assessment: an archival study
  32. Frequency and pathological significance of mucinous differentiation in colorectal adenocarcinoma using World Health Organization Classification of Tumours Fifth Edition criteria and nodal status as comparator: an archival study
  33. Correlation of signet-ring cell morphology with pathological stage at resection in colorectal carcinoma using routine histopathological examination: a retrospective study
  34. Agreement between colonoscopic impression and colorectal biopsy histopathology for adenoma and carcinoma using histopathology as reference standard: a retrospective diagnostic study
  35. Histopathological spectrum of colorectal polyps using World Health Organization Classification of Tumours Fifth Edition criteria and anatomical site as comparator: an archival study
  36. Correlation of colorectal polyp size with dysplasia grade using routine histopathological examination as reference assessment: an archival cross-sectional study
  37. Correlation of villous architecture with high-grade dysplasia in colorectal adenomas using routine histopathology as outcome assessment: an archival study
  38. Inter-observer agreement in grading dysplasia in colorectal adenomas using consensus microscopy as reference classification: an archival observer-agreement study
  39. Histopathological spectrum of appendicectomy specimens using gross findings and clinical diagnosis as comparators for acute, chronic and incidental lesions: a retrospective study
  40. Agreement between clinical diagnosis of acute appendicitis and histopathological examination of appendicectomy specimens using histopathology as reference standard: a retrospective study
  41. Frequency of incidental neoplasms in appendicectomy specimens using complete histopathological examination as reference assessment: a retrospective archival study
  42. Correlation of gross appendiceal findings with histological acute inflammation severity using routine appendicectomy specimens: a retrospective specimen-based study
  43. Histopathological spectrum of small intestinal biopsies from patients with chronic diarrhoea using endoscopic and clinical findings as comparators: a retrospective study
  44. Correlation of villous atrophy grade with intraepithelial lymphocyte density in duodenal biopsies from patients evaluated for malabsorption using routine histopathology: an archival study
  45. Inter-observer agreement in grading villous atrophy on duodenal biopsies using consensus microscopy as reference assessment: an archival study
  46. Diagnostic accuracy of duodenal biopsy histology for coeliac-pattern enteropathy using clinical and serological diagnosis where routinely available as composite reference standard: a retrospective study
  47. Prevalence of intestinal tuberculosis in gastrointestinal biopsies using histopathology, Ziehl-Neelsen stain and clinical diagnosis as reference assessment: an archival study
  48. Diagnostic yield of Ziehl-Neelsen stain in gastrointestinal granulomatous lesions using final clinicopathological diagnosis as reference standard for tuberculosis: an archival study
  49. Histological features distinguishing intestinal tuberculosis from Crohn-type inflammatory bowel disease using final clinicopathological diagnosis as reference classification: a retrospective case-control study
  50. Audit of gastrointestinal biopsy pathology turnaround time and adequacy using laboratory timestamps and predefined specimen-quality criteria as service-performance outcomes: a retrospective study

Hepatobiliary and Pancreatic Pathology

  1. Histopathological spectrum of cholecystectomy specimens using preoperative clinical and imaging diagnosis as comparator for inflammatory, metaplastic, dysplastic and malignant lesions: a retrospective study
  2. Prevalence of incidental gallbladder carcinoma in cholecystectomy specimens performed for presumed benign disease using complete histopathological examination as reference assessment: a retrospective study
  3. Correlation of gallstone presence with histological chronic cholecystitis severity in cholecystectomy specimens using routine gross and microscopic examination: an archival cross-sectional study
  4. Correlation of gallbladder intestinal metaplasia with dysplasia in cholecystectomy specimens using routine histopathology as outcome assessment: an archival study
  5. Association of pyloric metaplasia with chronic inflammation severity in gallbladder specimens using routine histopathological examination: an archival cross-sectional study
  6. Correlation of gallbladder wall thickness measured grossly with histological chronic inflammation and fibrosis severity using routine cholecystectomy specimens: a specimen-based study
  7. Diagnostic accuracy of gross suspicion for gallbladder carcinoma using histopathological examination as reference standard in cholecystectomy specimens: a retrospective study
  8. Correlation of gallbladder carcinoma histological grade with depth of invasion using resection histopathology as outcome assessment: an archival study
  9. Association of lymphovascular invasion with lymph node metastasis in gallbladder carcinoma using resection and nodal histopathology as reference assessment: an archival study
  10. Association of perineural invasion with pathological tumour category in gallbladder carcinoma using routine resection histopathology: an archival cross-sectional study
  11. Correlation of tumour differentiation with lymph node metastasis in gallbladder adenocarcinoma using resection histopathology and nodal examination: a retrospective study
  12. Frequency and pathological significance of dysplasia adjacent to gallbladder carcinoma using routine resection sections and tumour grade as comparator: an archival study
  13. Prevalence of xanthogranulomatous cholecystitis and its gross mimics of carcinoma using histopathology as reference standard: a retrospective study
  14. Histological features distinguishing xanthogranulomatous cholecystitis from gallbladder carcinoma using histopathologically confirmed specimens as reference groups: a retrospective case-control study
  15. Agreement between preoperative imaging impression and gallbladder histopathology for suspected malignancy using histopathology as reference standard: a retrospective diagnostic study
  16. Histopathological spectrum of liver biopsies using clinical indication and biochemical liver profile as comparators for inflammatory, fatty, fibrotic and neoplastic lesions: a retrospective study
  17. Correlation of steatosis grade with inflammatory activity in liver biopsies from patients with fatty liver disease using routine histopathological assessment: an archival study
  18. Correlation of steatosis grade with fibrosis stage in liver biopsies from patients with fatty liver disease using Masson trichrome stain as fibrosis comparator: an archival study
  19. Inter-observer agreement in grading hepatic steatosis on haematoxylin and eosin sections using consensus microscopy as reference assessment: an archival study
  20. Inter-observer agreement in hepatic fibrosis staging using Masson trichrome-stained liver biopsies and consensus review as reference assessment: an archival study
  21. Correlation of serum aminotransferase levels with histological inflammation grade in liver biopsies using routine biochemical results and pathology records: a retrospective clinicopathological study
  22. Correlation of serum bilirubin with histological cholestasis severity in liver biopsies using routine biochemical results as comparator: a retrospective study
  23. Diagnostic yield of Masson trichrome stain for hepatic fibrosis assessment compared with haematoxylin and eosin examination in routine liver biopsies: an archival comparative study
  24. Diagnostic yield of reticulin stain in evaluating altered hepatic architecture in liver biopsies with suspected chronic liver disease using final histopathological diagnosis as reference assessment: an archival study
  25. Diagnostic contribution of Perls Prussian blue stain in liver biopsies from patients with chronic liver disease using routine iron deposition grading as outcome measure: an archival study
  26. Prevalence and histological patterns of granulomatous hepatitis using haematoxylin and eosin sections with Ziehl-Neelsen and periodic acid-Schiff stains as adjunctive comparators: an archival study
  27. Diagnostic yield of Ziehl-Neelsen stain in hepatic granulomas using final clinicopathological diagnosis as reference standard for mycobacterial infection: an archival study
  28. Diagnostic yield of periodic acid-Schiff stain in hepatic granulomatous lesions using final clinicopathological diagnosis as reference standard for fungal organisms: an archival study
  29. Histopathological spectrum of hepatic space-occupying lesions sampled by core biopsy using imaging diagnosis and routine immunohistochemistry where available as comparators: a retrospective study
  30. Diagnostic accuracy of liver core biopsy for metastatic carcinoma using final clinical, imaging or resection diagnosis as reference standard: a retrospective study
  31. Correlation of tumour differentiation with necrosis in hepatocellular carcinoma biopsies or resections using routine histopathology: an archival cross-sectional study
  32. Diagnostic contribution of reticulin stain in suspected hepatocellular carcinoma using final histopathological diagnosis and routine immunohistochemistry where available as reference assessment: an archival study
  33. Histopathological spectrum of pancreatic biopsies and resections using radiological or operative diagnosis as clinical comparator for inflammatory and neoplastic lesions: a retrospective study
  34. Diagnostic accuracy of pancreatic fine needle aspiration or cytology for malignancy using biopsy or resection histopathology as reference standard: a retrospective study
  35. Correlation of pancreatic adenocarcinoma histological grade with lymph node metastasis using resection histopathology and nodal examination: an archival study
  36. Association of perineural invasion with lymph node metastasis in pancreatic adenocarcinoma using routine resection histopathology as outcome assessment: an archival study
  37. Association of lymphovascular invasion with pathological tumour category in pancreatic adenocarcinoma using routine resection histopathology: an archival cross-sectional study
  38. Histopathological spectrum of periampullary tumours using World Health Organization Classification of Tumours Fifth Edition criteria and anatomical site as comparator: an archival study
  39. Correlation of periampullary carcinoma histological subtype with lymph node metastasis using resection and nodal histopathology: a retrospective study
  40. Diagnostic accuracy of periampullary endoscopic biopsy for malignancy using subsequent resection histopathology as reference standard: a retrospective study
  41. Agreement between preoperative biopsy and resection histology in periampullary carcinoma for tumour type and differentiation grade: a retrospective agreement study
  42. Histopathological spectrum of extrahepatic bile duct biopsies using imaging and operative findings as comparators for inflammatory and malignant lesions: a retrospective study
  43. Diagnostic accuracy of bile duct biopsy for cholangiocarcinoma using resection histopathology or final clinicoradiological diagnosis as reference standard: a retrospective study
  44. Correlation of cholangiocarcinoma histological grade with perineural invasion using resection histopathology as outcome assessment: an archival study
  45. Association of lymphovascular invasion with nodal metastasis in cholangiocarcinoma using resection and lymph node histopathology: an archival study
  46. Diagnostic yield of bile cytology for malignant biliary obstruction using biopsy or resection histopathology as reference standard: a retrospective study
  47. Agreement between bile cytology and biliary biopsy in patients with obstructive jaundice using final histopathological diagnosis as reference assessment: a retrospective study
  48. Audit of cholecystectomy specimen sampling adequacy in suspected gallbladder malignancy using predefined grossing protocols and final detection of dysplasia or carcinoma as outcomes: a retrospective study
  49. Audit of liver biopsy adequacy using portal tract count and specimen length against predefined laboratory criteria with diagnostic yield as secondary outcome: a retrospective study
  50. Audit of hepatobiliary pathology turnaround time using laboratory timestamps and predefined institutional targets with special-stain completion time as secondary quality outcome: a retrospective study

Head, Neck and Oral Pathology

  1. Histopathological spectrum of oral cavity biopsies in patients with tobacco or smokeless tobacco exposure using clinical diagnosis as comparator for benign, premalignant and malignant lesions: a retrospective study
  2. Correlation of oral epithelial dysplasia grade with documented smokeless tobacco exposure in oral mucosal biopsies using routine histopathological assessment: a retrospective cross-sectional study
  3. Inter-observer agreement in grading oral epithelial dysplasia on haematoxylin and eosin sections using consensus microscopy as reference assessment: an archival study
  4. Correlation of oral epithelial dysplasia grade with p53 immunohistochemical expression where routinely performed using histological grade as comparator: an archival study
  5. Correlation of oral epithelial dysplasia grade with Ki-67 proliferation index where routinely performed using histopathological grade as reference assessment: an archival study
  6. Diagnostic accuracy of clinical suspicion for oral malignancy using biopsy histopathology as reference standard in patients with persistent oral lesions: a retrospective study
  7. Histopathological spectrum of leukoplakic oral lesions using clinical diagnosis and routine biopsy histopathology for classification of hyperkeratosis, dysplasia and carcinoma: a retrospective study
  8. Histopathological spectrum of erythroplakic and erythroleukoplakic oral lesions using clinical appearance and biopsy histopathology for detection of dysplasia and carcinoma: a retrospective study
  9. Correlation of oral squamous cell carcinoma histological grade with cervical lymph node metastasis using resection and nodal histopathology: a retrospective study
  10. Association of lymphovascular invasion with cervical lymph node metastasis in oral squamous cell carcinoma using routine resection histopathology as outcome assessment: an archival study
  11. Association of perineural invasion with cervical lymph node metastasis in oral squamous cell carcinoma using routine resection and nodal histopathology: an archival study
  12. Correlation of depth of invasion with cervical lymph node metastasis in oral squamous cell carcinoma using resection histopathology as reference assessment: a retrospective study
  13. Correlation of tumour budding with cervical lymph node metastasis in oral squamous cell carcinoma using routine haematoxylin and eosin sections: an archival study
  14. Inter-observer agreement in tumour budding assessment in oral squamous cell carcinoma using consensus microscopy as reference classification: an archival observer-agreement study
  15. Correlation of worst pattern of invasion with lymph node metastasis in oral squamous cell carcinoma using routine resection histopathology: an archival cross-sectional study
  16. Correlation of tumour-infiltrating lymphocyte density with histological grade in oral squamous cell carcinoma using routine haematoxylin and eosin sections: an archival study
  17. Inter-observer agreement in semiquantitative tumour-infiltrating lymphocyte assessment in oral squamous cell carcinoma using consensus microscopy as reference assessment: an archival study
  18. Correlation of surgical margin distance with histological risk features in oral squamous cell carcinoma using inked resection specimens and routine microscopy: a retrospective study
  19. Frequency and causes of positive margins in oral squamous cell carcinoma resections using histopathological margin assessment and re-resection findings where available as comparator: a retrospective study
  20. Correlation of mandibular bone invasion with tumour depth and nodal metastasis in oral squamous cell carcinoma using resection histopathology: a retrospective study
  21. Histopathological spectrum of salivary gland fine needle aspiration specimens reported by the Milan System for Reporting Salivary Gland Cytopathology using histopathology where available as reference: a retrospective study
  22. Risk of malignancy for each Milan System for Reporting Salivary Gland Cytopathology category using surgical histopathology as reference standard: a retrospective cross-sectional study
  23. Diagnostic accuracy of salivary gland fine needle aspiration cytology reported by the Milan System for Reporting Salivary Gland Cytopathology using histopathology as reference standard for malignancy: a cross-sectional study
  24. Inter-observer agreement in categorising salivary gland fine needle aspiration specimens by the Milan System for Reporting Salivary Gland Cytopathology using consensus microscopy as reference assessment: an archival study
  25. Diagnostic accuracy of fine needle aspiration cytology for pleomorphic adenoma using resection histopathology as reference standard: a retrospective study
  26. Diagnostic accuracy of fine needle aspiration cytology for Warthin tumour using resection histopathology as reference standard: a retrospective study
  27. Cytological features distinguishing pleomorphic adenoma from malignant salivary gland tumours using histopathologically confirmed cases as reference groups: a retrospective case-control study
  28. Diagnostic accuracy of chondromyxoid stroma on salivary gland cytology for pleomorphic adenoma using histopathology as reference standard: a retrospective study
  29. Diagnostic accuracy of oncocytic cells with lymphoid background for Warthin tumour using histopathology as reference standard: a retrospective study
  30. Frequency and histological outcomes of salivary gland aspirates categorised as neoplasm of uncertain malignant potential by the Milan System for Reporting Salivary Gland Cytopathology: a retrospective study
  31. Diagnostic contribution of cell-block preparation in salivary gland aspirates with suspected malignancy using resection histopathology as reference standard: a prospective observational study
  32. Agreement between conventional smears and cell-block preparations in salivary gland fine needle aspiration using histopathology as reference standard for tumour category: a comparative study
  33. Histopathological spectrum of parotid gland tumours using World Health Organization Classification of Tumours Fifth Edition criteria and preoperative cytology as comparator: an archival study
  34. Histopathological spectrum of submandibular gland tumours using World Health Organization Classification of Tumours Fifth Edition criteria and preoperative cytology as comparator: an archival study
  35. Cytohistological correlation of salivary gland lesions using the Milan System for Reporting Salivary Gland Cytopathology and corresponding surgical histopathology: a retrospective study
  36. Diagnostic accuracy of fine needle aspiration cytology for metastatic squamous cell carcinoma in cervical nodes from oral primary tumours using histopathology as reference standard: a cross-sectional study
  37. Histopathological spectrum of laryngeal biopsies using clinical and endoscopic impression as comparator for inflammatory, dysplastic and malignant lesions: a retrospective study
  38. Diagnostic accuracy of endoscopic suspicion for laryngeal carcinoma using biopsy histopathology as reference standard: a retrospective study
  39. Correlation of laryngeal squamous cell carcinoma grade with lymph node metastasis using resection and nodal histopathology: a retrospective study
  40. Association of lymphovascular invasion with nodal metastasis in laryngeal squamous cell carcinoma using routine resection histopathology: an archival study
  41. Histopathological spectrum of sinonasal masses using clinical and radiological impression as comparators for inflammatory, fungal and neoplastic lesions: a retrospective study
  42. Diagnostic yield of periodic acid-Schiff stain in sinonasal biopsies with suspected fungal infection using final clinicopathological diagnosis as reference standard: an archival study
  43. Correlation of fungal morphology on haematoxylin and eosin sections with periodic acid-Schiff positivity in sinonasal fungal disease using final pathology diagnosis as comparator: an archival study
  44. Histopathological spectrum of nasopharyngeal biopsies using endoscopic impression as comparator for inflammatory and malignant lesions: a retrospective study
  45. Diagnostic accuracy of nasopharyngeal biopsy for malignancy using final clinicopathological diagnosis as reference assessment: a retrospective study
  46. Histopathological spectrum of tonsillectomy specimens using clinical indication as comparator for chronic inflammation and unsuspected neoplasia: a retrospective study
  47. Frequency of incidental malignancy in adult tonsillectomy specimens using complete histopathological examination as reference assessment: a retrospective study
  48. Audit of oral biopsy specimen adequacy using predefined orientation and depth criteria with diagnostic yield as quality outcome: a retrospective laboratory study
  49. Audit of salivary gland fine needle aspiration adequacy using Milan System for Reporting Salivary Gland Cytopathology criteria and non-diagnostic rate as primary quality outcome: a retrospective study
  50. Audit of head-and-neck pathology turnaround time using laboratory information timestamps and predefined institutional targets with special-stain or immunohistochemistry completion time as secondary outcome: a retrospective study

Respiratory and Thoracic Pathology

  1. Diagnostic accuracy of sputum cytology for lung malignancy in patients with radiologically suspicious lesions using biopsy histopathology as reference standard: a retrospective cross-sectional study
  2. Diagnostic accuracy of bronchial brush cytology for lung carcinoma using bronchoscopic biopsy histopathology as reference standard: a cross-sectional study
  3. Diagnostic accuracy of bronchial wash cytology for lung carcinoma using bronchoscopic biopsy histopathology as reference standard: a cross-sectional study
  4. Comparative diagnostic yield of bronchial brushing and bronchial washing for lung malignancy using bronchoscopic biopsy histopathology as reference standard: a prospective observational study
  5. Diagnostic accuracy of combined bronchial brushing and washing cytology for lung malignancy using biopsy histopathology as reference standard: a cross-sectional study
  6. Cytohistological correlation of bronchial cytology and biopsy in suspected lung carcinoma using histopathological diagnosis as reference standard: a retrospective study
  7. Diagnostic accuracy of fine needle aspiration cytology for peripheral lung masses using core biopsy or resection histopathology as reference standard: a retrospective study
  8. Diagnostic contribution of cell-block preparation in respiratory cytology specimens with suspected malignancy using biopsy histopathology as reference standard: a prospective observational study
  9. Agreement between conventional cytology and cell-block diagnosis in bronchial washing specimens using histopathology as reference standard for malignancy: a comparative cross-sectional study
  10. Cytomorphological features distinguishing squamous cell carcinoma from adenocarcinoma in respiratory cytology using histopathology with routine immunohistochemistry as reference classification: a retrospective case-control study
  11. Diagnostic accuracy of keratinisation and tadpole cells on respiratory cytology for squamous cell carcinoma using histopathology as reference standard: a retrospective study
  12. Diagnostic accuracy of glandular clusters and cytoplasmic vacuolation on respiratory cytology for adenocarcinoma using histopathology as reference standard: a retrospective study
  13. Diagnostic accuracy of nuclear moulding and scant cytoplasm on respiratory cytology for small cell carcinoma using histopathology and routine immunohistochemistry as reference standard: a retrospective study
  14. Histopathological spectrum of lung biopsies using World Health Organization Classification of Tumours Fifth Edition criteria and radiological impression as comparator: an archival study
  15. Correlation of lung carcinoma histological subtype with age, sex and smoking history using biopsy or resection histopathology as outcome assessment: a retrospective study
  16. Correlation of lung carcinoma histological grade with lymph node metastasis using resection and nodal histopathology: an archival study
  17. Association of lymphovascular invasion with nodal metastasis in resected lung carcinoma using routine histopathology as outcome assessment: an archival study
  18. Association of visceral pleural invasion with lymph node metastasis in lung carcinoma using resection histopathology: a retrospective study
  19. Correlation of tumour size with nodal metastasis in resected lung carcinoma using histopathological measurement and lymph node examination: a retrospective study
  20. Histopathological spectrum of pleural biopsies using clinical and radiological diagnosis as comparators for tuberculosis, inflammation and malignancy: a retrospective study
  21. Diagnostic accuracy of pleural biopsy for tuberculosis using granulomatous histology, Ziehl-Neelsen stain and final clinical diagnosis as composite reference standard: a retrospective study
  22. Diagnostic yield of Ziehl-Neelsen stain in granulomatous pleural biopsies using final clinicopathological diagnosis as reference standard for mycobacterial infection: an archival study
  23. Diagnostic accuracy of pleural fluid cytology for malignant pleural effusion using pleural biopsy or confirmed underlying malignancy as reference standard: a cross-sectional study
  24. Diagnostic yield of cell-block preparation in pleural effusions with suspected malignancy using biopsy or clinical diagnosis as reference standard: a prospective observational study
  25. Comparative diagnostic yield of conventional smear and cell-block examination in pleural effusions using final malignant diagnosis as reference standard: a comparative cross-sectional study
  26. Correlation of pleural fluid cytomorphological pattern with histological type of underlying lung carcinoma using biopsy diagnosis as reference assessment: a retrospective study
  27. Diagnostic accuracy of pleural fluid cytology for metastatic adenocarcinoma using histopathology and routine immunohistochemistry where available as reference standard: a retrospective study
  28. Inter-observer agreement in classifying reactive mesothelial cells and malignant cells in pleural effusion cytology using consensus microscopy and final diagnosis as comparators: an observer-agreement study
  29. Diagnostic accuracy of three-dimensional cell clusters and nuclear atypia in pleural fluid cytology for malignancy using biopsy or clinical diagnosis as reference standard: a retrospective study
  30. Histopathological spectrum of mediastinal biopsies using radiological compartment and final histological diagnosis as clinicopathological comparators: a retrospective study
  31. Diagnostic accuracy of fine needle aspiration cytology for mediastinal masses using histopathology as reference standard where corresponding biopsy is available: a retrospective study
  32. Histopathological spectrum of thymic lesions using World Health Organization Classification of Tumours Fifth Edition criteria and radiological diagnosis as comparator: an archival study
  33. Correlation of thymoma histological type with tumour invasion documented on resection histopathology using World Health Organization Classification of Tumours Fifth Edition criteria: an archival study
  34. Histopathological spectrum of pulmonary tuberculosis in lung biopsies and resections using Ziehl-Neelsen stain and final clinical diagnosis as comparators: an archival study
  35. Diagnostic yield of Ziehl-Neelsen stain in pulmonary granulomatous biopsies using final clinicopathological diagnosis as reference standard for tuberculosis: an archival study
  36. Diagnostic yield of periodic acid-Schiff stain in pulmonary biopsies with fungal morphology using final clinicopathological diagnosis as reference standard: an archival study
  37. Histological features distinguishing tuberculosis from fungal granulomatous lung disease using special stains and final clinicopathological diagnosis as reference classification: a retrospective case-control study
  38. Histopathological spectrum of non-neoplastic lung resections using clinical and radiological diagnosis as comparators for infection, bronchiectasis and inflammatory lesions: a retrospective study
  39. Correlation of radiological cavitation with histopathological necrosis in pulmonary infectious lesions using resection or biopsy specimens: a retrospective clinicopathological study
  40. Histopathological spectrum of endobronchial biopsies in patients with suspected malignancy using bronchoscopy findings as comparator: a retrospective study
  41. Agreement between bronchoscopic visual impression and biopsy histopathology for lung malignancy using histopathology as reference standard: a retrospective study
  42. Correlation of tumour necrosis with histological subtype in lung carcinoma using routine biopsy or resection histopathology: an archival study
  43. Correlation of Ki-67 proliferation index with histological category in pulmonary neuroendocrine tumours where routine immunohistochemistry is available using final histopathological classification as reference: an archival study
  44. Inter-observer agreement in mitotic count assessment in pulmonary neuroendocrine tumours using consensus microscopy as reference assessment: an archival study
  45. Diagnostic accuracy of respiratory cytology for small cell carcinoma using biopsy histopathology and routine immunohistochemistry as reference standard: a retrospective study
  46. Frequency and causes of false-negative respiratory cytology in lung cancer using corresponding biopsy histopathology as reference standard: a retrospective diagnostic audit
  47. Frequency and causes of false-positive respiratory cytology for lung malignancy using corresponding biopsy histopathology as reference standard: a retrospective diagnostic audit
  48. Audit of bronchoscopic biopsy adequacy for lung malignancy using predefined tissue criteria and final diagnostic yield as quality outcomes: a retrospective study
  49. Audit of respiratory cytology adequacy and malignancy detection using specimen type, cellularity criteria and histopathological concordance as quality indicators: a retrospective study
  50. Audit of thoracic pathology turnaround time using laboratory information timestamps and predefined institutional targets with immunohistochemistry completion time as secondary outcome: a retrospective study

Renal and Urinary Tract Pathology

  1. Histopathological spectrum of native renal biopsies using clinical syndrome and routine light microscopy with special stains as comparators for glomerular, interstitial and vascular lesions: a retrospective study
  2. Correlation of proteinuria severity with glomerular histopathological pattern in native renal biopsies using routine clinical laboratory results as comparator: a retrospective clinicopathological study
  3. Correlation of serum creatinine with chronicity features in native renal biopsies using interstitial fibrosis and tubular atrophy grading on routine histopathology: an archival study
  4. Inter-observer agreement in grading interstitial fibrosis and tubular atrophy on native renal biopsies using consensus microscopy as reference assessment: an archival study
  5. Correlation of global glomerulosclerosis percentage with serum creatinine in native renal biopsies using routine histopathology and clinical chemistry results: a retrospective study
  6. Diagnostic contribution of periodic acid-Schiff stain in native renal biopsies compared with haematoxylin and eosin sections for assessment of glomerular basement membrane and mesangial abnormalities: an archival study
  7. Diagnostic contribution of Masson trichrome stain in native renal biopsies compared with routine haematoxylin and eosin examination for interstitial fibrosis assessment: an archival comparative study
  8. Diagnostic contribution of silver stain where routinely available in native renal biopsies using final histopathological diagnosis as reference assessment for glomerular capillary-wall abnormalities: an archival study
  9. Correlation of haematuria with histopathological glomerular lesions in native renal biopsies using routine urine microscopy and biopsy diagnosis as comparators: a retrospective study
  10. Correlation of hypertension with vascular and chronic parenchymal changes in native renal biopsies using routine histopathological grading as outcome assessment: a retrospective study
  11. Histopathological spectrum of renal biopsies in nephrotic syndrome using age and clinical diagnosis as comparators for major glomerular patterns: a retrospective study
  12. Histopathological spectrum of renal biopsies in nephritic syndrome using routine clinical diagnosis and urine findings as comparators: a retrospective study
  13. Histopathological spectrum of renal biopsies in rapidly progressive renal dysfunction using serum creatinine and clinical diagnosis as comparators for crescentic patterns: a retrospective study
  14. Correlation of crescent percentage with serum creatinine in crescentic glomerulonephritis using routine renal biopsy histopathology as outcome assessment: an archival study
  15. Inter-observer agreement in crescent percentage estimation on renal biopsies using consensus microscopy as reference assessment: an archival observer-agreement study
  16. Correlation of tubular atrophy grade with estimated renal dysfunction documented at biopsy using routine histopathological examination: a retrospective clinicopathological study
  17. Histopathological spectrum of nephrectomy specimens using preoperative imaging and clinical diagnosis as comparators for non-neoplastic and neoplastic lesions: a retrospective study
  18. Diagnostic accuracy of preoperative imaging impression for renal malignancy using nephrectomy histopathology as reference standard: a retrospective study
  19. Histopathological spectrum of renal cell carcinoma using World Health Organization Classification of Tumours Fifth Edition criteria and tumour size as comparator: an archival study
  20. Correlation of renal cell carcinoma histological grade with tumour size using nephrectomy histopathology: an archival cross-sectional study
  21. Correlation of renal cell carcinoma grade with tumour necrosis using routine nephrectomy histopathology as outcome assessment: an archival study
  22. Association of lymphovascular invasion with pathological tumour category in renal cell carcinoma using nephrectomy histopathology: an archival study
  23. Correlation of renal sinus invasion with tumour size in renal cell carcinoma using nephrectomy histopathology as reference assessment: a retrospective study
  24. Correlation of perinephric fat invasion with tumour grade in renal cell carcinoma using routine nephrectomy histopathology: an archival study
  25. Histopathological spectrum of non-neoplastic nephrectomy specimens using clinical indication and gross findings as comparators for hydronephrosis, pyelonephritis and calculous disease: a retrospective study
  26. Correlation of renal calculi with chronic pyelonephritis severity in nephrectomy specimens using routine histopathology: an archival cross-sectional study
  27. Frequency of xanthogranulomatous pyelonephritis in nephrectomy specimens and correlation with calculi and hydronephrosis using gross and microscopic findings: a retrospective study
  28. Histological features distinguishing xanthogranulomatous pyelonephritis from renal malignancy in nephrectomy specimens using final histopathological diagnosis as reference classification: a retrospective case-control study
  29. Diagnostic accuracy of urine cytology reported by the Paris System for Reporting Urinary Cytology for high-grade urothelial carcinoma using biopsy histopathology as reference standard: a cross-sectional study
  30. Risk of malignancy across Paris System for Reporting Urinary Cytology categories using corresponding urinary tract histopathology as reference standard: a retrospective study
  31. Cytohistological correlation of urine cytology reported by the Paris System for Reporting Urinary Cytology using biopsy or resection histopathology as reference assessment: a retrospective study
  32. Inter-observer agreement in urine cytology categorisation by the Paris System for Reporting Urinary Cytology using consensus microscopy as reference assessment: an archival study
  33. Diagnostic accuracy of nuclear-to-cytoplasmic ratio and hyperchromasia in urine cytology for high-grade urothelial carcinoma using histopathology as reference standard: a retrospective study
  34. Diagnostic contribution of cell-block preparation in urine specimens suspicious for malignancy using biopsy histopathology as reference standard: a prospective observational study
  35. Comparative diagnostic yield of conventional urine cytology and cell-block examination for urothelial carcinoma using histopathology as reference standard: a cross-sectional study
  36. Histopathological spectrum of urinary bladder biopsies using cystoscopic impression as comparator for inflammatory, preneoplastic and neoplastic lesions: a retrospective study
  37. Diagnostic accuracy of cystoscopic suspicion for bladder carcinoma using biopsy histopathology as reference standard: a retrospective study
  38. Correlation of urothelial carcinoma histological grade with muscularis propria invasion using biopsy or resection histopathology: an archival study
  39. Association of lymphovascular invasion with pathological tumour category in urothelial carcinoma using cystectomy histopathology: an archival study
  40. Correlation of tumour necrosis with histological grade in urothelial carcinoma using routine histopathology: an archival study
  41. Inter-observer agreement in grading urothelial carcinoma using World Health Organization Classification of Tumours Fifth Edition criteria and consensus microscopy as reference assessment: an archival study
  42. Agreement between transurethral biopsy grade and cystectomy grade in urothelial carcinoma using cystectomy histopathology as reference standard: a retrospective study
  43. Agreement between transurethral biopsy assessment of muscularis propria invasion and cystectomy pathological stage using cystectomy histopathology as reference standard: a retrospective study
  44. Frequency of muscularis propria absence in transurethral bladder tumour specimens and its association with diagnostic uncertainty using final pathology reports as outcome measures: a retrospective audit
  45. Histopathological spectrum of ureteric lesions using clinical and radiological diagnosis as comparators for inflammatory and neoplastic pathology: a retrospective study
  46. Histopathological spectrum of renal pelvis tumours using World Health Organization Classification of Tumours Fifth Edition criteria and tumour grade as comparator: an archival study
  47. Diagnostic accuracy of urine cytology for upper urinary tract urothelial carcinoma using biopsy or nephroureterectomy histopathology as reference standard: a retrospective study
  48. Audit of native renal biopsy adequacy using glomerular count and tissue composition against predefined laboratory standards with diagnostic yield as secondary outcome: a retrospective study
  49. Audit of transurethral bladder biopsy adequacy for muscularis propria representation using predefined reporting standards and repeat biopsy recommendation as outcome measure: a retrospective study
  50. Audit of renal and urinary tract pathology turnaround time using laboratory timestamps and predefined institutional targets with special-stain completion time as secondary outcome: a retrospective study

Male Genital and Prostatic Pathology

  1. Histopathological spectrum of prostate needle biopsies using serum prostate-specific antigen concentration and clinical indication as comparators for benign, premalignant and malignant lesions: a retrospective study
  2. Correlation of serum prostate-specific antigen concentration with prostate adenocarcinoma grade group on needle biopsy using routine histopathological diagnosis: a retrospective cross-sectional study
  3. Diagnostic accuracy of serum prostate-specific antigen thresholds for prostate adenocarcinoma using needle biopsy histopathology as reference standard: a retrospective diagnostic study
  4. Correlation of prostate-specific antigen density where routinely documented with biopsy diagnosis of carcinoma using histopathology as reference standard: a retrospective study
  5. Correlation of prostate adenocarcinoma grade group with serum prostate-specific antigen concentration using needle biopsy histopathology and routine laboratory records: an archival study
  6. Inter-observer agreement in Gleason pattern assignment and prostate adenocarcinoma grade grouping on needle biopsies using consensus microscopy as reference assessment: an archival study
  7. Agreement between prostate needle biopsy grade group and prostatectomy grade group using resection histopathology as reference standard: a retrospective agreement study
  8. Correlation of perineural invasion on prostate needle biopsy with prostatectomy pathological tumour category using resection histopathology as reference assessment: a retrospective study
  9. Association of perineural invasion with higher prostate adenocarcinoma grade group on needle biopsy using routine histopathology as outcome assessment: an archival study
  10. Correlation of percentage core involvement by carcinoma with prostate adenocarcinoma grade group using needle biopsy histopathology: an archival cross-sectional study
  11. Association of number of positive biopsy cores with prostatectomy pathological tumour category using resection histopathology as reference assessment: a retrospective study
  12. Correlation of tumour volume estimate on needle biopsy with prostatectomy tumour extent using resection histopathology as reference assessment: a retrospective study
  13. Diagnostic accuracy of suspicious small acinar proliferation on needle biopsy for subsequent prostate adenocarcinoma using repeat biopsy or prostatectomy histopathology as reference outcome: a retrospective study
  14. Histological outcomes of high-grade prostatic intraepithelial neoplasia on needle biopsy using subsequent repeat biopsy or prostatectomy histopathology as reference assessment: a retrospective study
  15. Frequency and histological patterns of chronic prostatitis in prostate biopsies using serum prostate-specific antigen and clinical diagnosis as comparators: a retrospective study
  16. Correlation of chronic prostatic inflammation severity with serum prostate-specific antigen concentration in benign prostate biopsies using routine histopathology: a retrospective study
  17. Histopathological spectrum of transurethral prostate resection specimens using clinical diagnosis and serum prostate-specific antigen as comparators: a retrospective study
  18. Prevalence of incidental prostate adenocarcinoma in transurethral resection specimens performed for presumed benign enlargement using complete histopathological examination as reference assessment: a retrospective study
  19. Correlation of prostate gland weight with benign prostatic hyperplasia histological pattern using transurethral or prostatectomy specimens: a retrospective specimen-based study
  20. Histopathological spectrum of orchidectomy specimens using clinical and imaging diagnosis as comparators for torsion, infection, atrophy and neoplasia: a retrospective study
  21. Histopathological spectrum of testicular tumours using World Health Organization Classification of Tumours Fifth Edition criteria and patient age as comparator: an archival study
  22. Correlation of testicular germ cell tumour histological type with serum tumour markers where routinely available using resection histopathology as reference classification: a retrospective study
  23. Correlation of lymphovascular invasion with tumour size in testicular germ cell tumours using orchidectomy histopathology: an archival study
  24. Association of rete testis invasion with tumour size in testicular seminoma using orchidectomy histopathology: an archival study
  25. Correlation of tumour necrosis with histological type in testicular germ cell tumours using routine orchidectomy histopathology: an archival study
  26. Inter-observer agreement in histological classification of testicular germ cell tumours using World Health Organization Classification of Tumours Fifth Edition criteria and consensus diagnosis as reference: an archival study
  27. Histopathological spectrum of epididymal and paratesticular masses using clinical and imaging diagnosis as comparators for benign and malignant lesions: a retrospective study
  28. Histopathological spectrum of penile biopsies using clinical diagnosis as comparator for inflammatory, premalignant and malignant lesions: a retrospective study
  29. Correlation of penile squamous cell carcinoma histological grade with lymphovascular invasion using routine resection histopathology: an archival cross-sectional study
  30. Association of perineural invasion with tumour grade in penile squamous cell carcinoma using routine histopathology: an archival study
  31. Correlation of depth of invasion with lymphovascular invasion in penile squamous cell carcinoma using resection histopathology: an archival study
  32. Histopathological spectrum of foreskin specimens submitted for pathological examination using clinical indication as comparator for inflammatory, premalignant and malignant lesions: a retrospective study
  33. Prevalence of lichen sclerosus in adult circumcision specimens using routine histopathological examination and clinical diagnosis as comparator: a retrospective study
  34. Histopathological spectrum of infertility-related testicular biopsies using clinical diagnosis and seminiferous tubular morphology as outcome assessment: a retrospective study
  35. Correlation of seminiferous tubular diameter with spermatogenic pattern in testicular biopsies from men evaluated for infertility using routine histopathology: an archival study
  36. Inter-observer agreement in classification of spermatogenic patterns on testicular biopsy using consensus microscopy as reference assessment: an archival study
  37. Correlation of Sertoli-cell-only pattern with testicular volume where documented in infertility evaluations using biopsy histopathology as reference assessment: a retrospective study
  38. Histopathological spectrum of hydrocele sac specimens using clinical diagnosis as comparator for chronic inflammation and unexpected lesions: a retrospective study
  39. Frequency of unexpected pathological findings in hydrocele sac specimens using complete histopathological examination as reference assessment: a retrospective study
  40. Histopathological spectrum of scrotal skin lesions using clinical diagnosis as comparator for inflammatory and neoplastic lesions: a retrospective study
  41. Diagnostic accuracy of fine needle aspiration cytology in palpable testicular or paratesticular masses where routinely performed using histopathology as reference standard: a retrospective study
  42. Correlation of gross appearance with histological diagnosis in testicular tumours using orchidectomy specimens and routine microscopy: a retrospective specimen-based study
  43. Diagnostic accuracy of intraoperative gross assessment for testicular neoplasia using final histopathology as reference standard where documented: a retrospective study
  44. Correlation of prostate adenocarcinoma tumour percentage with grade group on needle biopsy using routine histopathological assessment: an archival study
  45. Frequency of cribriform architecture in prostate adenocarcinoma and correlation with grade group using routine needle biopsy or prostatectomy histopathology: an archival study
  46. Inter-observer agreement in identifying cribriform architecture in prostate adenocarcinoma using consensus microscopy as reference assessment: an archival study
  47. Correlation of extraprostatic extension with grade group in radical prostatectomy specimens using routine histopathology: an archival study
  48. Association of seminal vesicle invasion with prostate adenocarcinoma grade group using radical prostatectomy histopathology: an archival study
  49. Audit of prostate needle biopsy adequacy using core length and number of cores against predefined laboratory criteria with cancer detection as secondary outcome: a retrospective study
  50. Audit of male genital pathology turnaround time using laboratory information timestamps and predefined institutional targets with immunohistochemistry completion time as secondary outcome: a retrospective study

Dermatopathology

  1. Histopathological spectrum of skin biopsies from clinically suspected infectious dermatoses using clinical diagnosis and special stains where indicated as comparators: a retrospective study
  2. Diagnostic accuracy of clinical diagnosis in leprosy using skin biopsy histopathology as reference standard for disease confirmation and spectrum classification: a retrospective study
  3. Clinicopathological agreement in classification of leprosy spectrum using clinical category and skin biopsy histopathology as comparative assessments: a retrospective agreement study
  4. Diagnostic yield of modified acid-fast staining where routinely performed in leprosy biopsies using histopathological diagnosis as reference assessment for bacillary detection: an archival study
  5. Correlation of bacillary load on routine special stain with histological leprosy spectrum using skin biopsy diagnosis as comparator: an archival study
  6. Inter-observer agreement in histopathological classification of leprosy using consensus microscopy as reference assessment: an archival observer-agreement study
  7. Diagnostic accuracy of clinical suspicion for cutaneous tuberculosis using skin biopsy histopathology, Ziehl-Neelsen stain and final clinical diagnosis as composite reference standard: a retrospective study
  8. Diagnostic yield of Ziehl-Neelsen stain in granulomatous skin biopsies using final clinicopathological diagnosis as reference standard for mycobacterial infection: an archival study
  9. Histological patterns of cutaneous tuberculosis and their correlation with Ziehl-Neelsen positivity using final clinical diagnosis as reference assessment: an archival study
  10. Diagnostic yield of periodic acid-Schiff stain in skin biopsies with suspected fungal infection using final clinicopathological diagnosis as reference standard: an archival study
  11. Correlation of fungal morphology on haematoxylin and eosin sections with periodic acid-Schiff positivity in cutaneous fungal infections using final pathology diagnosis as comparator: an archival study
  12. Histopathological spectrum of non-infectious vesiculobullous disorders using clinical diagnosis and routine biopsy morphology as comparators: a retrospective study
  13. Clinicopathological agreement in pemphigus vulgaris using clinical impression and skin biopsy histopathology as comparative assessments: a retrospective study
  14. Histological features distinguishing pemphigus vulgaris from bullous pemphigoid using biopsy-confirmed cases as reference groups: a retrospective case-control study
  15. Histopathological spectrum of papulosquamous dermatoses using clinical diagnosis as comparator for psoriasis, lichen planus and related disorders: a retrospective study
  16. Diagnostic accuracy of clinical psoriasis using skin biopsy histopathology as reference standard in biopsied cases: a retrospective study
  17. Correlation of neutrophils in stratum corneum and epidermal hyperplasia with histological psoriasis diagnosis using consensus microscopy as reference assessment: an archival study
  18. Diagnostic accuracy of clinical lichen planus using skin biopsy histopathology as reference standard in biopsied lesions: a retrospective study
  19. Histological features distinguishing psoriasis from chronic dermatitis using biopsy-confirmed cases as reference groups: a retrospective case-control study
  20. Inter-observer agreement in grading epidermal hyperplasia, spongiosis and interface change in inflammatory dermatoses using consensus microscopy as reference assessment: an archival study
  21. Histopathological spectrum of vasculitic skin lesions using clinical diagnosis and vessel-wall morphology as comparators: a retrospective study
  22. Correlation of leukocytoclasis and fibrinoid necrosis with clinical small-vessel vasculitis diagnosis using routine skin biopsy histopathology: an archival study
  23. Histopathological spectrum of panniculitis using clinical diagnosis and septal-versus-lobular pattern as comparative parameters: a retrospective study
  24. Inter-observer agreement in classifying panniculitis as septal, lobular or mixed using consensus microscopy as reference assessment: an archival study
  25. Histopathological spectrum of pigmentary skin lesions using clinical diagnosis as comparator for melanocytic and non-melanocytic lesions: a retrospective study
  26. Diagnostic accuracy of clinical diagnosis of melanocytic nevus using skin biopsy histopathology as reference standard: a retrospective study
  27. Histopathological spectrum of epidermal cystic lesions using clinical diagnosis as comparator for epidermoid, pilar and related cysts: a retrospective study
  28. Agreement between clinical diagnosis and histopathology in common benign skin tumours using histopathology as reference standard: a retrospective study
  29. Histopathological spectrum of adnexal skin tumours using World Health Organization Classification of Tumours Fifth Edition criteria and anatomical site as comparator: an archival study
  30. Clinicopathological correlation of sweat gland tumours using clinical impression and histopathological classification as comparative assessments: a retrospective study
  31. Clinicopathological correlation of hair follicle tumours using clinical impression and histopathological diagnosis as comparative assessments: a retrospective study
  32. Histopathological spectrum of sebaceous lesions using clinical diagnosis and routine biopsy morphology as comparators: a retrospective study
  33. Histopathological spectrum of keratinocytic malignancies using World Health Organization Classification of Tumours Fifth Edition criteria and anatomical site as comparator: an archival study
  34. Correlation of cutaneous squamous cell carcinoma histological grade with depth of invasion using excision histopathology: an archival study
  35. Association of perineural invasion with tumour depth in cutaneous squamous cell carcinoma using routine excision histopathology: an archival study
  36. Correlation of lymphovascular invasion with histological grade in cutaneous squamous cell carcinoma using routine histopathology: an archival study
  37. Histopathological spectrum of basal cell carcinoma using World Health Organization Classification of Tumours Fifth Edition criteria and anatomical site as comparator: an archival study
  38. Correlation of basal cell carcinoma histological subtype with margin involvement using excision histopathology: a retrospective study
  39. Frequency and causes of positive surgical margins in basal cell carcinoma excisions using inked histopathological margins and re-excision findings where available as comparator: a retrospective study
  40. Histopathological spectrum of melanocytic lesions using clinical diagnosis and routine histopathology as comparators for benign nevi and melanoma: a retrospective study
  41. Correlation of melanoma thickness with ulceration using excision histopathology as outcome assessment: an archival study
  42. Correlation of mitotic activity with melanoma thickness using routine histopathological sections: an archival cross-sectional study
  43. Inter-observer agreement in measuring melanoma thickness using consensus microscopic measurement as reference assessment: an archival study
  44. Histopathological spectrum of cutaneous lymphoid infiltrates using clinical diagnosis and basic immunohistochemistry where routinely performed as comparators: a retrospective study
  45. Histological features distinguishing reactive lymphoid infiltrates from cutaneous lymphoma using final clinicopathological diagnosis as reference classification: a retrospective case-control study
  46. Histopathological spectrum of diabetic foot debridement and amputation specimens using clinical infection status as comparator for ulceration, osteomyelitis and vascular changes: a retrospective study
  47. Correlation of tissue necrosis severity with acute inflammation in diabetic foot specimens using routine histopathology: an archival study
  48. Audit of skin biopsy adequacy using depth, orientation and representation of diagnostic compartment against predefined laboratory criteria with diagnostic yield as outcome: a retrospective study
  49. Audit of special-stain utilisation in dermatopathology using indication, positivity and final diagnosis as measures of diagnostic yield: a retrospective laboratory study
  50. Audit of dermatopathology turnaround time using laboratory information timestamps and predefined institutional targets with special-stain completion time as secondary outcome: a retrospective study

Bone and Soft Tissue Pathology

  1. Histopathological spectrum of bone tumours using World Health Organization Classification of Tumours Fifth Edition criteria and radiological diagnosis as comparator: an archival cross-sectional study
  2. Agreement between radiological impression and histopathological diagnosis in primary bone tumours using histopathology as reference standard: a retrospective study
  3. Correlation of patient age and anatomical site with histological category of bone tumours using routine biopsy and resection pathology: a retrospective study
  4. Diagnostic accuracy of core biopsy for primary bone tumours using subsequent resection histopathology as reference standard: a retrospective study
  5. Agreement between core biopsy and resection diagnosis in bone tumours using final resection histopathology as reference assessment: a retrospective study
  6. Histological features distinguishing giant cell tumour of bone from other giant-cell-rich lesions using histopathologically confirmed cases as reference groups: a retrospective case-control study
  7. Correlation of mitotic activity with local aggressiveness documented radiologically in giant cell tumour of bone using biopsy or resection histopathology: a retrospective study
  8. Histopathological spectrum of osteogenic tumours using World Health Organization Classification of Tumours Fifth Edition criteria and radiological matrix pattern as comparator: an archival study
  9. Correlation of osteosarcoma histological subtype with tumour necrosis percentage in resection specimens where preoperative treatment was given as standard care: a retrospective observational study
  10. Inter-observer agreement in estimating tumour necrosis percentage in resected osteosarcoma using consensus microscopy as reference assessment: an archival study
  11. Histopathological spectrum of cartilaginous tumours using World Health Organization Classification of Tumours Fifth Edition criteria and radiological diagnosis as comparator: an archival study
  12. Histological features distinguishing enchondroma from low-grade chondrosarcoma using final multidisciplinary diagnosis as reference classification: a retrospective case-control study
  13. Inter-observer agreement in grading chondrosarcoma using consensus histological grade as reference assessment: an archival study
  14. Correlation of chondrosarcoma histological grade with tumour size using resection histopathology: an archival cross-sectional study
  15. Histopathological spectrum of metastatic tumours involving bone using biopsy histopathology and documented primary tumour site as comparators: a retrospective study
  16. Diagnostic accuracy of bone biopsy morphology for metastatic carcinoma using known primary tumour histopathology and basic immunohistochemistry where available as reference standard: a retrospective study
  17. Histopathological spectrum of osteomyelitis in bone biopsies and resections using clinical diagnosis, microbiology where available and special stains as comparators: a retrospective study
  18. Diagnostic yield of Ziehl-Neelsen stain in granulomatous bone lesions using final clinicopathological diagnosis as reference standard for tuberculosis: an archival study
  19. Diagnostic yield of periodic acid-Schiff stain in bone lesions with suspected fungal infection using final clinicopathological diagnosis as reference standard: an archival study
  20. Histological features distinguishing tuberculous osteomyelitis from pyogenic osteomyelitis using final clinicopathological diagnosis as reference classification: a retrospective case-control study
  21. Histopathological spectrum of soft tissue tumours using World Health Organization Classification of Tumours Fifth Edition criteria and anatomical site as comparator: an archival study
  22. Agreement between clinical or radiological diagnosis and histopathological diagnosis in soft tissue masses using histopathology as reference standard: a retrospective study
  23. Diagnostic accuracy of fine needle aspiration cytology for soft tissue tumours using biopsy or resection histopathology as reference standard: a retrospective study
  24. Diagnostic accuracy of core biopsy for soft tissue sarcoma using resection histopathology as reference standard: a retrospective study
  25. Agreement between core biopsy histological type and resection histological type in soft tissue sarcomas using final resection diagnosis as reference assessment: a retrospective study
  26. Agreement between core biopsy grade and resection grade in soft tissue sarcomas using final resection histopathology as reference standard: a retrospective study
  27. Correlation of soft tissue sarcoma histological grade with tumour size using resection histopathology: an archival cross-sectional study
  28. Correlation of tumour necrosis with histological grade in soft tissue sarcomas using routine resection histopathology: an archival study
  29. Association of lymphovascular invasion with histological grade in soft tissue sarcoma using routine resection histopathology: an archival study
  30. Correlation of mitotic count with histological grade in soft tissue sarcomas using routine haematoxylin and eosin sections: an archival study
  31. Inter-observer agreement in mitotic counting in soft tissue sarcomas using consensus microscopy as reference assessment: an archival observer-agreement study
  32. Inter-observer agreement in soft tissue sarcoma grading using consensus histological grade as reference assessment: an archival study
  33. Histopathological spectrum of adipocytic tumours using World Health Organization Classification of Tumours Fifth Edition criteria and anatomical site as comparator: an archival study
  34. Histological features distinguishing lipoma from atypical adipocytic tumour using final histopathological diagnosis as reference classification: a retrospective case-control study
  35. Histopathological spectrum of peripheral nerve sheath tumours using World Health Organization Classification of Tumours Fifth Edition criteria and anatomical site as comparator: an archival study
  36. Histological features distinguishing schwannoma from neurofibroma using histopathologically confirmed specimens as reference groups: a retrospective case-control study
  37. Correlation of degenerative change with tumour size in schwannoma using resection histopathology: an archival study
  38. Histopathological spectrum of vascular tumours using World Health Organization Classification of Tumours Fifth Edition criteria and clinical diagnosis as comparator: an archival study
  39. Histological features distinguishing benign vascular proliferations from malignant vascular tumours using final histopathological diagnosis as reference classification: a retrospective case-control study
  40. Histopathological spectrum of fibrohistiocytic tumours using World Health Organization Classification of Tumours Fifth Edition criteria and anatomical site as comparator: an archival study
  41. Histopathological spectrum of smooth muscle tumours of soft tissue using World Health Organization Classification of Tumours Fifth Edition criteria and anatomical site as comparator: an archival study
  42. Correlation of mitotic count with necrosis in smooth muscle tumours of soft tissue using resection histopathology: an archival study
  43. Histopathological spectrum of benign soft tissue masses in extremities using clinical diagnosis and routine histopathology as comparators: a retrospective study
  44. Prevalence of unexpected malignancy among clinically benign soft tissue masses using excision histopathology as reference assessment: a retrospective study
  45. Correlation of surgical margin status with tumour size in soft tissue sarcoma resections using inked histopathological margin assessment: a retrospective study
  46. Frequency and causes of positive margins in soft tissue sarcoma resections using routine margin histopathology and re-excision findings where available as comparator: a retrospective study
  47. Audit of bone tumour biopsy adequacy using viable tissue representation and decalcification quality against predefined laboratory standards with diagnostic yield as outcome: a retrospective study
  48. Audit of decalcification-related morphological artefacts in bone specimens using predefined microscopy criteria and need for repeat sectioning as quality outcomes: a retrospective study
  49. Audit of soft tissue tumour immunohistochemistry utilisation using initial morphology, panel size and final diagnostic category as measures of diagnostic efficiency: a retrospective study
  50. Audit of bone and soft tissue pathology turnaround time using laboratory timestamps and predefined institutional targets with decalcification duration as secondary outcome: a retrospective study

Central Nervous System Pathology

  1. Histopathological spectrum of central nervous system tumours using World Health Organization Classification of Tumours Fifth Edition criteria and anatomical site as comparator: an archival cross-sectional study
  2. Correlation of patient age with histological category of central nervous system tumours using routine surgical pathology specimens: a retrospective study
  3. Correlation of anatomical site with histological type of central nervous system tumour using World Health Organization Classification of Tumours Fifth Edition criteria: an archival study
  4. Agreement between radiological impression and histopathological diagnosis in intracranial tumours using histopathology as reference standard: a retrospective study
  5. Diagnostic accuracy of intraoperative squash cytology for central nervous system tumours using paraffin-section histopathology as reference standard: a cross-sectional study
  6. Agreement between intraoperative squash cytology and paraffin-section diagnosis in central nervous system tumours using final histopathology as reference assessment: a retrospective study
  7. Diagnostic accuracy of squash cytology for glioma using paraffin-section histopathology as reference standard: a retrospective study
  8. Diagnostic accuracy of squash cytology for meningioma using paraffin-section histopathology as reference standard: a retrospective study
  9. Diagnostic accuracy of squash cytology for metastatic carcinoma in the central nervous system using histopathology and basic immunohistochemistry as reference standard: a retrospective study
  10. Frequency and causes of discordance between intraoperative cytology and final histopathology in central nervous system tumours using final diagnosis as reference standard: a retrospective audit
  11. Histopathological spectrum of gliomas using World Health Organization Classification of Tumours Fifth Edition morphological criteria and age as comparator where molecular testing is unavailable: an archival study
  12. Correlation of mitotic count with histological grade in diffusely infiltrating astrocytic tumours using routine haematoxylin and eosin sections: an archival study
  13. Correlation of microvascular proliferation with histological grade in astrocytic tumours using routine histopathology: an archival cross-sectional study
  14. Correlation of necrosis with histological grade in astrocytic tumours using routine histopathology: an archival study
  15. Correlation of Ki-67 proliferation index with histological grade in gliomas where routine immunohistochemistry is performed using final integrated pathological diagnosis as comparator: an archival study
  16. Inter-observer agreement in Ki-67 proliferation index estimation in gliomas using consensus microscopic assessment as reference: an archival study
  17. Inter-observer agreement in mitotic counting in gliomas using consensus microscopy as reference assessment: an archival observer-agreement study
  18. Histopathological spectrum of meningiomas using World Health Organization Classification of Tumours Fifth Edition criteria and anatomical site as comparator: an archival study
  19. Correlation of meningioma histological grade with mitotic count using routine resection histopathology: an archival study
  20. Correlation of brain invasion with meningioma histological grade using routine resection specimens: an archival cross-sectional study
  21. Correlation of necrosis with meningioma histological grade using routine haematoxylin and eosin sections: an archival study
  22. Inter-observer agreement in grading meningiomas using World Health Organization Classification of Tumours Fifth Edition criteria and consensus diagnosis as reference: an archival study
  23. Correlation of Ki-67 proliferation index with histological grade in meningiomas where routinely performed using final pathological classification as comparator: an archival study
  24. Histopathological spectrum of pituitary region lesions using radiological diagnosis and routine histopathology with basic immunohistochemistry as comparators: a retrospective study
  25. Correlation of pituitary neuroendocrine tumour cytological atypia with Ki-67 proliferation index where routinely performed using final histopathological diagnosis as comparator: an archival study
  26. Histopathological spectrum of spinal tumours using World Health Organization Classification of Tumours Fifth Edition criteria and anatomical compartment as comparator: an archival study
  27. Agreement between radiological compartment diagnosis and histopathological tumour type in spinal masses using histopathology as reference standard: a retrospective study
  28. Histopathological spectrum of peripheral nerve tumours involving the neuraxis using World Health Organization Classification of Tumours Fifth Edition criteria and anatomical site as comparator: an archival study
  29. Histopathological spectrum of paediatric central nervous system tumours using World Health Organization Classification of Tumours Fifth Edition criteria and age group as comparator: a retrospective study
  30. Correlation of posterior fossa location with histological tumour type in paediatric central nervous system tumours using routine surgical pathology: a retrospective study
  31. Diagnostic accuracy of squash cytology in paediatric posterior fossa tumours using paraffin-section histopathology as reference standard: a retrospective study
  32. Cytological features distinguishing medulloblastoma from ependymoma on squash preparations using paraffin-section histopathology as reference classification: a retrospective case-control study
  33. Correlation of Ki-67 proliferation index with histological category in medulloblastoma where routinely performed using final histopathological diagnosis as comparator: an archival study
  34. Histopathological spectrum of ependymal tumours using World Health Organization Classification of Tumours Fifth Edition morphological criteria and anatomical site as comparator: an archival study
  35. Correlation of mitotic activity with histological grade in ependymal tumours using routine histopathology: an archival study
  36. Histopathological spectrum of metastatic central nervous system tumours using morphology, basic immunohistochemistry and documented primary tumour as comparators: a retrospective study
  37. Diagnostic accuracy of histomorphology for identifying the primary category of central nervous system metastasis using known primary tumour diagnosis and basic immunohistochemistry as reference assessment: a retrospective study
  38. Histopathological spectrum of non-neoplastic brain biopsies using clinical and radiological diagnosis as comparators for infection, inflammation and demyelinating lesions: a retrospective study
  39. Diagnostic yield of Ziehl-Neelsen stain in central nervous system granulomatous lesions using final clinicopathological diagnosis as reference standard for tuberculosis: an archival study
  40. Diagnostic yield of periodic acid-Schiff stain in central nervous system lesions with suspected fungal infection using final clinicopathological diagnosis as reference standard: an archival study
  41. Histological features distinguishing tuberculous granulomas from fungal granulomas in central nervous system biopsies using special stains and final diagnosis as reference classification: a retrospective case-control study
  42. Histopathological spectrum of brain abscess specimens using clinical diagnosis, microbiology where available and routine histopathology as comparators: a retrospective study
  43. Histopathological spectrum of temporal lobe resections for epilepsy using clinical and radiological diagnosis as comparators for gliosis, sclerosis and neoplasia: a retrospective study
  44. Correlation of hippocampal neuronal loss and gliosis with clinical diagnosis of mesial temporal sclerosis using routine resection histopathology: an archival study
  45. Histopathological spectrum of sellar and suprasellar masses using imaging diagnosis and routine pathology as comparators: a retrospective study
  46. Agreement between radiological diagnosis and histopathological diagnosis in sellar and suprasellar masses using histopathology as reference standard: a retrospective study
  47. Audit of central nervous system biopsy adequacy using viable tissue representation and crush artefact against predefined criteria with final diagnostic yield as outcome: a retrospective study
  48. Audit of intraoperative squash cytology diagnostic concordance using final paraffin histopathology as reference standard and major discrepancy rate as quality indicator: a retrospective study
  49. Audit of basic immunohistochemistry utilisation in central nervous system tumours using morphology, number of markers and final diagnosis as measures of diagnostic efficiency: a retrospective study
  50. Audit of central nervous system pathology turnaround time using laboratory information timestamps and predefined institutional targets with immunohistochemistry completion time as secondary outcome: a retrospective study

Paediatric and Perinatal Pathology

  1. Histopathological spectrum of paediatric surgical pathology specimens using age group, anatomical site and clinical diagnosis as comparators for common benign and malignant lesions: a retrospective study
  2. Histopathological spectrum of paediatric lymph node biopsies using clinical diagnosis as comparator for reactive, infectious and malignant lesions: a retrospective study
  3. Diagnostic accuracy of fine needle aspiration cytology in paediatric lymphadenopathy using histopathology or final clinical diagnosis as reference standard: a cross-sectional study
  4. Prevalence and cytomorphological patterns of tuberculous lymphadenitis in children using Ziehl-Neelsen stain and final clinicopathological diagnosis as comparators: a retrospective study
  5. Histopathological spectrum of paediatric gastrointestinal biopsies using clinical indication as comparator for inflammatory, infectious and congenital lesions: a retrospective study
  6. Correlation of villous atrophy with intraepithelial lymphocyte density in duodenal biopsies from children evaluated for malabsorption using routine histopathology: an archival study
  7. Histopathological spectrum of appendicectomy specimens in children using clinical diagnosis and gross findings as comparators: a retrospective study
  8. Agreement between clinical diagnosis of acute appendicitis and histopathology in paediatric appendicectomy specimens using histopathology as reference standard: a retrospective study
  9. Histopathological spectrum of paediatric nephrectomy specimens using clinical and imaging diagnosis as comparators for congenital, inflammatory and neoplastic lesions: a retrospective study
  10. Correlation of Wilms tumour histological components with tumour size in nephrectomy specimens using routine histopathological assessment: an archival study
  11. Correlation of tumour necrosis percentage with histological pattern in Wilms tumour specimens following routine preoperative therapy where applicable: a retrospective observational study
  12. Inter-observer agreement in assessing tumour necrosis percentage in Wilms tumour nephrectomy specimens using consensus microscopy as reference assessment: an archival study
  13. Histopathological spectrum of paediatric testicular masses using clinical and imaging diagnosis as comparators for benign and malignant lesions: a retrospective study
  14. Histopathological spectrum of paediatric ovarian masses using World Health Organization Classification of Tumours Fifth Edition criteria and age as comparator: a retrospective study
  15. Correlation of ovarian germ cell tumour histological type with serum tumour markers where routinely available using resection histopathology as reference classification: a retrospective study
  16. Histopathological spectrum of paediatric soft tissue tumours using World Health Organization Classification of Tumours Fifth Edition criteria and anatomical site as comparator: an archival study
  17. Agreement between core biopsy and resection diagnosis in paediatric soft tissue tumours using final histopathology as reference standard: a retrospective study
  18. Histopathological spectrum of small round cell tumours in children using routine morphology and basic immunohistochemistry as reference classification: an archival study
  19. Diagnostic accuracy of initial morphology for paediatric small round cell tumours using final basic immunohistochemical diagnosis as reference standard: a retrospective study
  20. Histopathological spectrum of paediatric bone tumours using World Health Organization Classification of Tumours Fifth Edition criteria and radiological diagnosis as comparator: an archival study
  21. Agreement between radiological impression and histopathological diagnosis in paediatric bone tumours using histopathology as reference standard: a retrospective study
  22. Histopathological spectrum of Hirschsprung disease resection and biopsy specimens using clinical diagnosis and ganglion-cell assessment as comparators: a retrospective study
  23. Diagnostic accuracy of rectal biopsy for Hirschsprung disease using subsequent resection histopathology or final clinical diagnosis as reference standard: a retrospective study
  24. Inter-observer agreement in ganglion-cell identification in rectal biopsies for suspected Hirschsprung disease using consensus microscopy as reference assessment: an archival study
  25. Histopathological spectrum of congenital gastrointestinal obstruction specimens in children using operative findings as comparator for atresia, stenosis and malrotation-associated pathology: a retrospective study
  26. Histopathological spectrum of paediatric liver biopsies using clinical indication and biochemical profile as comparators for neonatal cholestasis, metabolic-pattern and inflammatory lesions: a retrospective study
  27. Correlation of cholestasis severity with portal inflammation in paediatric liver biopsies using routine histopathological grading: an archival study
  28. Histopathological spectrum of biliary atresia specimens using operative diagnosis and liver biopsy findings as comparators: a retrospective study
  29. Correlation of portal fibrosis grade with age at biopsy in infants with biliary atresia using Masson trichrome stain as fibrosis assessment: an archival study
  30. Histopathological spectrum of paediatric skin biopsies using clinical diagnosis as comparator for inflammatory, infectious and genetic-pattern dermatoses: a retrospective study
  31. Histopathological spectrum of congenital cystic lesions in children using clinical and imaging diagnosis as comparators for final pathological classification: a retrospective study
  32. Histopathological spectrum of paediatric head-and-neck masses using clinical diagnosis and fine needle aspiration where available as comparators: a retrospective study
  33. Diagnostic accuracy of fine needle aspiration cytology in paediatric head-and-neck masses using histopathology as reference standard where corresponding biopsy is available: a retrospective study
  34. Histopathological spectrum of placental lesions in pregnancies with foetal growth restriction using birth weight and gestational age as clinical comparators: a retrospective study
  35. Correlation of placental infarction percentage with low birth weight using gross and microscopic placental examination and neonatal weight as outcome assessment: a retrospective study
  36. Correlation of maternal hypertension with placental maternal vascular malperfusion features using routine placental histopathology as outcome assessment: a retrospective study
  37. Correlation of maternal diabetes with placental villous maturation abnormalities using routine placental histopathology as outcome assessment: a retrospective study
  38. Histopathological spectrum of placentas from preterm deliveries using gestational age and maternal clinical diagnosis as comparators: a retrospective study
  39. Correlation of acute chorioamnionitis severity with documented maternal fever or neonatal sepsis evaluation using routine placental histopathology: a retrospective study
  40. Inter-observer agreement in grading acute chorioamnionitis on placental sections using consensus microscopy as reference assessment: an archival study
  41. Correlation of placental weight with neonatal birth weight using routine gross examination and delivery records: a retrospective observational study
  42. Histopathological spectrum of placentas from stillbirths using gestational age and documented maternal or foetal risk factors as comparators: a retrospective study
  43. Correlation of placental thrombotic lesions with stillbirth using routine histopathology and matched live-birth placentas as comparator groups: a retrospective case-control study
  44. Histopathological spectrum of products of conception specimens using clinical diagnosis as comparator for miscarriage, molar pregnancy and other gestational lesions: a retrospective study
  45. Diagnostic accuracy of pre-evacuation clinical or ultrasonographic suspicion for hydatidiform mole using histopathology as reference standard: a retrospective study
  46. Inter-observer agreement in histological classification of hydatidiform mole using consensus microscopy and p57 immunohistochemistry where routinely performed as reference assessment: an archival study
  47. Histopathological spectrum of paediatric autopsy tissues where institutional autopsy material is routinely available using premortem clinical diagnosis as comparator for major diagnostic discrepancies: a retrospective study
  48. Audit of placental examination adequacy using predefined grossing and sampling criteria with detection of clinically significant lesions as outcome measure: a retrospective study
  49. Audit of paediatric biopsy specimen adequacy using tissue volume, orientation and diagnostic yield against predefined laboratory quality standards: a retrospective study
  50. Audit of paediatric and perinatal pathology turnaround time using laboratory timestamps and predefined institutional targets with special-stain completion time as secondary outcome: a retrospective study

Body Fluids, Exfoliative Cytology and Infectious Cytopathology

  1. Diagnostic accuracy of pleural fluid cytology for malignancy using pleural biopsy or confirmed primary malignancy as reference standard in adults with pleural effusion: a cross-sectional study
  2. Diagnostic accuracy of ascitic fluid cytology for malignancy using peritoneal biopsy or confirmed intra-abdominal malignancy as reference standard: a cross-sectional study
  3. Diagnostic accuracy of peritoneal wash cytology for metastatic carcinoma using peritoneal or omental histopathology as reference standard: a retrospective study
  4. Diagnostic accuracy of cerebrospinal fluid cytology for malignant cells using confirmed haematological or solid malignancy diagnosis as reference standard: a retrospective study
  5. Diagnostic accuracy of pericardial fluid cytology for malignancy using biopsy or confirmed underlying malignancy as reference standard: a retrospective study
  6. Comparative diagnostic yield of conventional smear and cell-block examination in pleural fluid specimens using final malignant diagnosis as reference standard: a cross-sectional study
  7. Comparative diagnostic yield of conventional smear and cell-block examination in ascitic fluid specimens using final malignant diagnosis as reference standard: a cross-sectional study
  8. Incremental diagnostic yield of cell-block preparation over conventional smears in serous effusions suspicious for malignancy using final clinicopathological diagnosis as reference standard: a prospective observational study
  9. Agreement between conventional smear and cell-block cytology in malignant pleural effusions using biopsy or confirmed primary malignancy as reference assessment: a comparative study
  10. Agreement between conventional smear and cell-block cytology in malignant ascitic effusions using biopsy or confirmed primary malignancy as reference assessment: a comparative study
  11. Diagnostic accuracy of three-dimensional clusters, nuclear irregularity and macronucleoli in pleural effusion cytology for malignancy using final diagnosis as reference standard: a retrospective study
  12. Diagnostic accuracy of three-dimensional clusters and cytoplasmic vacuolation in ascitic fluid cytology for adenocarcinoma using final histopathological diagnosis as reference standard: a retrospective study
  13. Inter-observer agreement in distinguishing reactive mesothelial proliferation from metastatic adenocarcinoma in serous effusion cytology using consensus microscopy and final diagnosis as comparators: an archival study
  14. Diagnostic contribution of basic cell-block immunohistochemistry in cytologically indeterminate serous effusions using final histopathological diagnosis as reference standard: an archival study
  15. Correlation of malignant cell burden graded on effusion cytology with cell-block tumour cellularity using paired specimens: a cross-sectional correlation study
  16. Diagnostic accuracy of ascitic fluid cytology for ovarian carcinoma dissemination using omental or peritoneal histopathology as reference standard: a retrospective study
  17. Diagnostic accuracy of ascitic fluid cytology for gastrointestinal carcinoma dissemination using biopsy-confirmed malignancy and peritoneal histopathology as reference standard: a retrospective study
  18. Correlation of pleural fluid cytological tumour type with histological subtype of underlying lung carcinoma using biopsy diagnosis as reference assessment: a retrospective study
  19. Correlation of ascitic fluid cytological tumour morphology with histological type of ovarian carcinoma using surgical histopathology as reference assessment: a retrospective study
  20. Frequency and causes of false-negative malignant effusion cytology using subsequent cell block, biopsy or confirmed primary malignancy as reference standard: a retrospective diagnostic audit
  21. Frequency and causes of false-positive malignant effusion cytology using subsequent biopsy and clinical diagnosis as reference standard: a retrospective diagnostic audit
  22. Diagnostic yield of repeat pleural fluid cytology after an initially negative specimen in patients with subsequently confirmed malignancy using final diagnosis as reference outcome: a retrospective study
  23. Diagnostic yield of repeat ascitic fluid cytology after an initially negative specimen in patients with subsequently confirmed malignancy using final diagnosis as reference outcome: a retrospective study
  24. Audit of serous fluid specimen adequacy using cellularity, volume and final diagnostic category as quality outcome measures: a retrospective laboratory study
  25. Correlation of submitted pleural fluid volume with cytological adequacy and malignancy detection using routine laboratory specimens: a retrospective study
  26. Correlation of submitted ascitic fluid volume with cytological adequacy and malignancy detection using routine laboratory specimens: a retrospective study
  27. Diagnostic accuracy of urine cytology reported by the Paris System for Reporting Urinary Cytology for high-grade urothelial carcinoma using biopsy histopathology as reference standard: a cross-sectional study
  28. Diagnostic contribution of urine cell-block preparation in specimens suspicious for urothelial carcinoma using biopsy histopathology as reference standard: a prospective observational study
  29. Diagnostic accuracy of sputum cytology for pulmonary malignancy using biopsy histopathology as reference standard: a retrospective study
  30. Diagnostic accuracy of cervical cytology for high-grade squamous intraepithelial lesions using cervical biopsy histopathology as reference standard: a retrospective study
  31. Diagnostic accuracy of fine needle aspiration cytology for tuberculous lymphadenitis using final clinicopathological diagnosis and Ziehl-Neelsen stain as reference assessments: a cross-sectional study
  32. Diagnostic yield of Ziehl-Neelsen staining in necrotic lymph node aspirates using final clinicopathological diagnosis as reference standard for tuberculosis: a cross-sectional study
  33. Correlation of granuloma formation with Ziehl-Neelsen positivity in lymph node aspirates diagnosed as granulomatous lymphadenitis using final clinical diagnosis as comparator: a cross-sectional study
  34. Diagnostic yield of Ziehl-Neelsen staining in pus-like aspirates from lymph nodes using final clinicopathological diagnosis as reference standard for tuberculosis: a cross-sectional study
  35. Diagnostic yield of periodic acid-Schiff stain in cytology specimens with suspected fungal infection using final clinicopathological diagnosis as reference standard: an archival study
  36. Cytomorphological patterns of fungal infection in fine needle aspiration specimens using periodic acid-Schiff positivity and final diagnosis as reference classification: an archival study
  37. Diagnostic accuracy of cytological suppurative inflammation for bacterial infection in aspirates using routine culture where available and clinical diagnosis as reference assessment: a cross-sectional study
  38. Correlation of neutrophil-rich cytology with culture positivity in aspirated abscess material submitted for routine pathology and microbiology evaluation: a retrospective cross-sectional study
  39. Diagnostic accuracy of cytology in salivary gland inflammatory lesions using histopathology or final clinical diagnosis as reference standard: a retrospective study
  40. Diagnostic accuracy of cytology for granulomatous mastitis using core biopsy histopathology and special stains as reference standard: a cross-sectional study
  41. Correlation of cytological granuloma burden with histological granulomatous inflammation in paired breast aspirate and biopsy specimens: a retrospective study
  42. Diagnostic accuracy of cytology for thyroiditis using histopathology or integrated clinical diagnosis as reference standard in thyroid fine needle aspiration specimens: a retrospective study
  43. Diagnostic accuracy of cytology for metastatic malignancy in supraclavicular lymph nodes using histopathology or documented primary malignancy as reference standard: a cross-sectional study
  44. Diagnostic yield of cell-block preparation in supraclavicular lymph node aspirates suspicious for malignancy using histopathology as reference standard: a prospective observational study
  45. Inter-observer agreement in malignant-versus-benign classification of body fluid cytology using consensus microscopy and final clinicopathological diagnosis as comparators: an archival study
  46. Intra-observer reproducibility of serous fluid cytology categorisation using blinded repeat review and final consensus diagnosis as reference assessment: an archival agreement study
  47. Audit of body fluid cytology reporting turnaround time using laboratory information timestamps and predefined institutional targets with cell-block completion time as secondary outcome: a retrospective study
  48. Audit of cell-block adequacy in serous effusions using cellularity criteria and incremental diagnostic yield over conventional smears as quality outcomes: a retrospective study
  49. Audit of special-stain utilisation in infectious cytopathology using indication, positivity rate and final diagnosis as measures of diagnostic yield: a retrospective laboratory study
  50. Audit of cytology-histology discordance across body fluid and exfoliative cytology specimens using paired diagnoses and major discrepancy categories as quality indicators: a retrospective study

Laboratory Quality Assurance, Special Stains and Pathology Service Audits

  1. Audit of surgical pathology specimen rejection using predefined identification, container and fixation criteria with repeat submission and diagnostic delay as outcome measures: a retrospective quality-assurance study
  2. Audit of histopathology specimen fixation adequacy using documented fixation time and microscopic artefact criteria with repeat processing as outcome measure: a retrospective study
  3. Correlation of fixation delay with histological artefact severity in routine surgical pathology specimens using predefined microscopic quality criteria: a retrospective observational study
  4. Audit of grossing-to-report turnaround time in routine surgical pathology using laboratory information timestamps against predefined institutional targets: a retrospective quality study
  5. Audit of biopsy turnaround time by specimen category using laboratory information timestamps and predefined service standards as performance outcomes: a retrospective study
  6. Audit of large resection specimen turnaround time using laboratory information timestamps and immunohistochemistry requirement as comparative parameter: a retrospective study
  7. Correlation of number of tissue blocks submitted with report turnaround time in major resection specimens using routine laboratory information records: a retrospective study
  8. Audit of repeat section requests in histopathology using cause, specimen type and final diagnostic impact as quality outcome measures: a retrospective laboratory study
  9. Audit of deeper-section utilisation in small biopsies using indication and change in final diagnosis as measures of incremental diagnostic yield: a retrospective study
  10. Diagnostic yield of deeper sections in initially non-diagnostic gastrointestinal biopsies using final pathology diagnosis as reference outcome: a retrospective study
  11. Diagnostic yield of deeper sections in initially non-diagnostic skin biopsies using final pathology diagnosis as reference outcome: a retrospective study
  12. Diagnostic yield of deeper sections in cervical biopsies with suspected epithelial lesions using final pathology diagnosis as reference outcome: a retrospective study
  13. Audit of haematoxylin and eosin staining quality using predefined nuclear and cytoplasmic staining criteria with repeat staining rate as outcome measure: a laboratory quality study
  14. Inter-observer agreement in grading haematoxylin and eosin staining quality using predefined scoring criteria and consensus assessment as reference: a laboratory agreement study
  15. Audit of periodic acid-Schiff stain utilisation using specimen type, indication, positivity rate and contribution to final diagnosis as measures of diagnostic yield: a retrospective study
  16. Audit of Ziehl-Neelsen stain utilisation using specimen type, indication, positivity rate and contribution to final diagnosis as measures of diagnostic yield: a retrospective study
  17. Audit of Congo red stain utilisation using specimen type, indication, positivity rate and final amyloid diagnosis as measures of diagnostic yield: a retrospective study
  18. Audit of Perls Prussian blue stain utilisation using specimen type, indication, iron grade and contribution to final diagnosis as outcome measures: a retrospective study
  19. Audit of Masson trichrome stain utilisation using specimen type, indication, fibrosis assessment and contribution to final diagnosis as outcome measures: a retrospective study
  20. Audit of reticulin stain utilisation in bone marrow and liver pathology using indication, grading result and contribution to final diagnosis as outcome measures: a retrospective study
  21. Agreement between two observers in bone marrow iron grading using Perls Prussian blue stain and consensus microscopy as reference assessment: an archival agreement study
  22. Agreement between two observers in bone marrow reticulin fibrosis grading using consensus microscopy as reference assessment: an archival observer-agreement study
  23. Agreement between two observers in liver fibrosis grading on Masson trichrome stain using consensus microscopy as reference assessment: an archival study
  24. Audit of immunohistochemistry request patterns using specimen type, number of markers, provisional morphology and final diagnosis as measures of diagnostic efficiency: a retrospective study
  25. Proportion of routine immunohistochemistry panels resulting in change from provisional morphological diagnosis using final pathology report as outcome measure: a retrospective audit
  26. Correlation of immunohistochemistry panel size with report turnaround time in malignant biopsies using laboratory information timestamps as service outcome: a retrospective study
  27. Audit of repeat immunohistochemistry staining using technical failure, tissue exhaustion and interpretative causes as quality outcome categories: a retrospective study
  28. Audit of paraffin block tissue exhaustion in small biopsies using specimen type, number of levels and immunohistochemistry requests as associated parameters: a retrospective study
  29. Audit of cytology specimen inadequacy across thyroid, breast, lymph node and salivary gland aspirates using reporting-system adequacy criteria as reference standards: a retrospective study
  30. Comparative adequacy rates of thyroid, breast, salivary gland and lymph node fine needle aspiration specimens using predefined cytological criteria as quality outcomes: a retrospective study
  31. Audit of cytology-histology discordance in thyroid lesions using paired Bethesda System for Reporting Thyroid Cytopathology categories and resection histopathology as reference assessment: a retrospective study
  32. Audit of cytology-histology discordance in breast lesions using International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology categories and histopathology as reference: a retrospective study
  33. Audit of cytology-histology discordance in salivary gland lesions using Milan System for Reporting Salivary Gland Cytopathology categories and resection histopathology as reference: a retrospective study
  34. Audit of urine cytology-histology discordance using Paris System for Reporting Urinary Cytology categories and urinary tract biopsy histopathology as reference: a retrospective study
  35. Audit of cervical cytology-histology discordance using Bethesda System for Reporting Cervical Cytology categories and cervical biopsy histopathology as reference: a retrospective study
  36. Audit of amended pathology reports using reason for amendment, specimen type and potential clinical significance as quality outcome measures: a retrospective study
  37. Audit of critical pathology result communication using documented notification time against institutional policy as reference standard for compliance: a retrospective quality study
  38. Audit of specimen identification errors in histopathology and cytology using laboratory incident records and predefined error categories as outcome measures: a retrospective study
  39. Audit of preanalytical errors in pathology specimens using labelling, fixation, container and requisition completeness criteria as quality indicators: a retrospective study
  40. Audit of pathology requisition form completeness using predefined mandatory clinical-information fields and impact on diagnostic clarification requests as outcome measures: a retrospective study
  41. Correlation of incomplete clinical information with report turnaround time in biopsy specimens using laboratory information timestamps and requisition completeness scores: a retrospective study
  42. Audit of frozen section diagnostic concordance where routinely performed using permanent paraffin-section histopathology as reference standard and major discrepancy rate as quality indicator: a retrospective study
  43. Diagnostic accuracy of frozen section for benign-versus-malignant classification where routinely performed using permanent paraffin-section histopathology as reference standard: a retrospective study
  44. Audit of decalcified specimen turnaround time using decalcification duration, specimen size and final reporting time as service-performance outcomes: a retrospective study
  45. Correlation of decalcification duration with histomorphological preservation in bone specimens using predefined microscopic artefact criteria: a retrospective study
  46. Audit of tissue block and slide retrieval from pathology archives using retrieval success rate and retrieval time against predefined departmental standards as quality outcomes: a retrospective study
  47. Audit of paraffin block labelling and archival traceability using random block-to-register verification against predefined laboratory identification standards: a cross-sectional quality study
  48. Audit of pathology report completeness in cancer resections using predefined mandatory histopathological parameters and institutional reporting templates as reference standards: a retrospective study
  49. Audit of lymph node yield reporting in major oncological resections using specimen-specific minimum documentation requirements and final pathology reports as quality measures: a retrospective study
  50. Comprehensive audit of preanalytical, analytical and postanalytical quality indicators in a teaching-hospital pathology department using predefined departmental benchmarks for specimen rejection, turnaround time, diagnostic concordance and amended reports: a retrospective quality-assurance study

Not the pathology subspeciality you need? Master list of pathology is one section of our full pathology collection — the hub page lists every subspeciality, each with its own free topic list. Updated September 2026.

Browse all Pathology Thesis Topics →

📌 Updated for 2026–2027 MD Pathology admissions

The master list has been reviewed for current tumour classification, cytology terminology, molecularly integrated diagnosis, digital pathology and practical laboratory-based study design.

  • Most topics can be completed with routine microscopy, automated laboratory analysers, cytology, histopathology, special stains, selected immunohistochemistry, immunofluorescence or routine clinical records according to the chosen section.
  • Whole-genome sequencing, broad research panels, dedicated digital scanners and research-only invasive sampling are not required for most feasible MD dissertations; advanced methods should be added only when already available and central to the primary question.
  • Publication potential is strongest when the project uses a current classification system, a clearly independent reference standard, reproducible specimen-quality criteria, observer-agreement methods or a measurable laboratory quality indicator.
Generate a protocol from any topic above

Select Generate Protocol → beside any title in the list above and receive a submission-ready document built around that topic, containing all eighteen components:

  • Introduction / Synopsis
  • Research Question
  • Aim of the Study
  • Primary Objective
  • Secondary Objectives
  • Materials and Methods
  • Inclusion Criteria
  • Exclusion Criteria
  • Sample Size Calculation
  • Methodology
  • Statistical Analysis
  • Ethical Considerations
  • Review of Literature
  • References
  • Gantt Chart / Study Timeline
  • Patient Information Sheet
  • Consent Form
  • Data Collection Form

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Alongside master list of pathology protocols and synopses, support is also available for departmental presentations, journal club presentations, ethics committee presentations, and posters and oral presentations for medical conferences — for postgraduate residents, board trainees and research scholars across India and the GCC. Prepared by a practising doctor with long experience in medical publishing and thesis supervision.

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Master list of pathology research outside India

The topics above work as research questions anywhere — what changes is the document the institution expects, and who approves it before data collection begins. The Gulf equivalent of an Indian synopsis is the master list of pathology research proposal submitted to an institutional review board, and it ordinarily carries three sections an Indian synopsis does not: a Gantt chart, a budget and resources section, and a Declaration of Helsinki statement.

Board and residency programmes — country by country

Saudi Arabia — SCFHS and the Saudi Board. Residency and fellowship training under the Saudi Commission for Health Specialties includes a research project with a set timeline, and the master list of pathology research proposal is the document prepared at the outset and cleared by the institutional review board before recruitment starts.

United Arab Emirates — DHA, DOH Abu Dhabi and MOHAP. Residents training in Dubai, Abu Dhabi and the northern emirates prepare a master list of pathology research protocol for their programme and submit it for institutional review board approval before any data are collected.

Qatar — DHP (formerly QCHP) and Hamad Medical Corporation. A master list of pathology IRB proposal is reviewed before recruitment, with the ethics section written to the institution's own template rather than a generic one.

Bahrain — NHRA. Trainees turning master list of pathology research topics into a project need the proposal cleared by their institutional research and ethics committee before fieldwork begins.

Oman — OMSB. Residency programmes under the Oman Medical Specialty Board include a research component, and the master list of pathology research proposal is the document assessed at the start of it.

Kuwait — KIMS. A master list of pathology study protocol goes to the institutional committee for approval before the project begins.

Arab Board programmes across the region. The Arab Board carries its own research requirement irrespective of the host country, and the master list of pathology proposal follows the same structure throughout.

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Postgraduate degrees — Malaysia, the Gulf and beyond

Malaysia — MMed, the National Medical Research Register and MREC. A master list of pathology dissertation proposal for a Master of Medicine programme carried out in a Ministry of Health facility must be registered on the NMRR and approved by the Medical Research and Ethics Committee before the study begins, and the guidance asks for submission four to six months ahead of data collection. Every investigator on the study team registers on the NMRR as well, so the methodology, ethics and team sections are written in far more detail than an Indian synopsis requires.

PhD and Master's candidates elsewhere. University programmes generally require a full master list of pathology research proposal of roughly 6,000 to 10,000 words, with an extended literature review, a theoretical framework and a detailed methodology chapter.

PhD and MMed proposals are written individually by a medical doctor and revised until the supervisor accepts them. They are not produced by the automated protocol generator.

Enquire about a master list of pathology PhD or MMed proposal →

🔥 Trending research areas in Pathology for 2026–27

  • Completed WHO fifth-edition tumour classification: the current Blue Book series now provides a unified framework across organ systems with increasing integration of histomorphology, diagnostic molecular pathology and genetic tumour syndromes.
  • Digital pathology and artificial intelligence validation: current research is moving from proof-of-concept image classification toward reproducibility, workflow integration, external validation, error analysis and comparison with conventional microscopy.
  • Molecularly integrated diagnosis using practical surrogates: morphology combined with targeted immunohistochemistry, in-situ methods or selected molecular tests is increasingly used to approximate or support classifications that cannot be resolved by morphology alone.
  • Standardised cytology and laboratory quality metrics: current Bethesda, Paris, Yokohama and other structured reporting systems create thesis opportunities around risk of malignancy, inter-observer agreement, cytohistological discordance, specimen adequacy and laboratory turnaround or error indicators.

Protocol and synopsis guidance

What a Pathology protocol must contain

A pathology protocol should define the unit of analysis before recruitment begins. The unit may be a patient, specimen, biopsy, resection, blood sample, cytology preparation or laboratory episode. Multiple blocks, slides, fields or cells from one patient can provide repeated measurements, but they do not automatically become independent study participants.

Specimen and pre-analytical definition: state how material is collected, fixed, transported, processed and judged adequate. In laboratory studies this includes anticoagulant, storage and analysis interval; in histopathology it includes fixation, sampling and block selection; in cytology it includes adequacy and preparation method.

Diagnostic criteria: name the classification, grading system, reporting terminology or laboratory threshold being used. If an older archived diagnosis is reclassified under a current system, the protocol should state whether original reports or blinded slide review provide the study diagnosis.

Reference standard: define what establishes the final diagnosis. Histology, immunohistochemistry, molecular testing, microbiology, flow cytometry, clinical follow-up and multidisciplinary diagnosis may each be appropriate in different projects. A comparator should not be called a gold standard merely because it is more complex than the index test.

Observer handling: morphology studies should define reader number, experience, blinding, diagnostic thresholds and how disagreement is resolved. When the same pathologist rereads slides, the interval and de-identification procedure should be specified for intra-observer studies.

Pathology synopsis versus Pathology protocol

A synopsis gives the committee the problem, rationale, objectives, broad methods and sample size. The protocol is the operational document and should make specimen selection, laboratory workflow, morphological criteria and analysis reproducible enough that another resident could collect the same variables from the same material.

For diagnostic-accuracy studies: define the index test, threshold, reference standard and verification pathway. If only patients with an abnormal index test proceed to biopsy or definitive investigation, sensitivity and specificity may be biased.

For morphology studies: define the exact feature being measured, magnification or counting approach where relevant, number of observers, blinding and whether consensus is part of the reference classification. A consensus diagnosis is appropriate for some agreement questions but should not be confused with an independent biological truth.

For archival studies: define how cases are retrieved, whether missing blocks or faded slides are excluded, whether reclassification is performed and how changes in classification or laboratory methods over the archive period are handled.

For laboratory studies: define analyser platform, internal quality-control status, specimen rejection rules, repeat-testing policy and how analytical error is separated from biological variation. Derived indices should not be treated as independent measurements when they are calculated from the same underlying variables.

Sample size and statistical analysis

Sample size should be calculated from the primary objective rather than from the number of variables available. Prevalence, diagnostic accuracy, agreement, correlation, paired method comparison and laboratory audit questions require different assumptions and should not use one generic formula.

Unit of analysis: sample-size calculations should count independent patients or other prespecified independent units. If several slides, blocks, fields or serial samples are analysed from the same patient, clustering or repeated-measures methods may be required.

Agreement versus association: Pearson or Spearman correlation measures association, not agreement. Method-comparison studies may require bias and limits of agreement; categorical observer studies may require kappa; continuous reader measurements may require an intraclass correlation coefficient.

Diagnostic accuracy: sensitivity, specificity, predictive values and likelihood ratios require a defined index test and reference standard. Verification bias, incorporation bias and case-control sampling can materially alter apparent diagnostic performance and should be considered before analysis.

Rare outcomes: rare tumours and uncommon laboratory events are often better handled as descriptive archival series, pooled categories or focused agreement studies than as unstable multivariable models. The number of predictors should be limited by the number of actual outcome events.

Frequently Asked Questions – Master List Of Pathology Thesis Topics (2026–27)

1. How do I choose a feasible Pathology thesis topic?

For 2026–2027 admissions, begin with the material your department already generates in adequate numbers: complete blood counts, smears, bone marrow specimens, blood-bank records, fine-needle aspirates, biopsies, resections, body fluids, special stains or quality-control data. A strong topic has one primary question, a realistic case yield and a comparator or outcome that can be retrieved consistently.

2. Which study designs are accepted for a Pathology thesis?

Common designs include cross-sectional descriptive studies, diagnostic-accuracy studies, method-comparison studies, inter-observer or intra-observer agreement studies, retrospective archival studies, cytohistological correlation, clinicopathological correlation, immunohistochemical studies and laboratory quality audits. The design should follow the question rather than being labelled cross-sectional by default.

3. What should I settle with my guide before registering a Pathology topic?

Settle the primary objective, independent unit of analysis, expected case yield, specimen type, minimum adequacy, reference standard, classification system, ancillary tests, observer workflow and availability of clinical follow-up. For archival projects, confirm that slides, blocks and reports are retrievable before registration.

4. Can an archival Pathology thesis be methodologically strong?

Yes. Archival pathology can be particularly strong for uncommon tumours, observer agreement, biopsy-resection concordance, immunohistochemistry, cytology-histology correlation and quality audits. The protocol should measure missing data and unavailable tissue, define the archive period and account for changes in classifications, stains, analysers or clinical practice that occurred during that period.

5. What is the difference between a Pathology synopsis and a Pathology protocol?

The synopsis is the concise approval document describing the research question, objectives, broad methods and sample size. The protocol should additionally define specimen handling, eligibility, adequacy, classification criteria, reference standard, blinding, repeat measurements, data variables and the statistical test for the primary objective.

6. What ethical issues are important in a Pathology thesis?

Prospective participants require informed consent, with guardian consent and age-appropriate child assent from about seven years when children are directly recruited. Retrospective use of archived slides, blocks, laboratory data and records may qualify for a waiver of consent after ethics-committee approval and appropriate anonymisation. No biopsy, bone marrow procedure, additional radiation, contrast investigation or other invasive test should be performed only to satisfy a dissertation endpoint. Research-only venepuncture requires a justified volume and frequency. Separate consent is required for identifiable photographs or videos. Clinically actionable unexpected findings discovered during research review should have a predefined pathway for communication to the treating team.

7. What should count as one case in a Pathology thesis?

The independent unit should be defined from the research question. In many studies one patient is one case, even if that patient contributes several blocks, slides, fields, aspirations or stains. In other studies the true unit may be a blood donation, blood component, laboratory sample or transfusion episode. Treating multiple observations from the same patient as independent cases creates pseudoreplication and can exaggerate precision. If repeated samples or multiple lesions are scientifically necessary, the protocol should prespecify a patient-level rule or use statistical methods that account for clustering and repeated measurements.

8. How does a Pathology dissertation differ from research-proposal pathways outside the Indian MD?

An Indian MD dissertation usually develops from a focused synopsis into a detailed protocol for institutional ethics and university registration. A PhD proposal is broader and supports a larger programme of original work. In Gulf training pathways, the requirement may instead be a supervised board research project; programmes linked to SCFHS and the Saudi Board, the Arab Board of Health Specializations, and DHP, DHA, DOH or MOHAP may use different approval, supervision and submission structures. The scientific core remains a defined question, reproducible methods, ethical approval and a prespecified analysis plan.

9. When should I register my Pathology thesis topic?

Register after a short feasibility review confirms that enough eligible cases, specimens or laboratory records exist and that the proposed reference standard can actually be obtained. Checking a small run of recent cases before registration often reveals missing clinical data, inadequate specimens, unavailable blocks or ancillary tests, or an unexpectedly low case frequency.

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