Infectious Diseases Thesis Topics For MD/DNB Medicine

Infectious Diseases Research Topics

This page brings together infectious diseases thesis topics and infectious disease research topics suitable for MD/DNB Medicine residents, covering acute febrile illness, dengue, pneumonia, urinary infections, enteric fever, tuberculosis, malaria, sepsis, human immunodeficiency virus infection, central nervous system infections, acute gastroenteritis, viral hepatitis, skin and soft-tissue infections, zoonotic and vector-borne infections, antimicrobial resistance and hospital-acquired infection. Most designs can be completed within one thesis period using patients, routine microbiology, standard laboratory investigations, imaging obtained during care and hospital records already available in teaching hospitals. Before registration, the selected question should be converted into a department-specific MD Medicine infectious diseases protocol and MD Medicine infectious diseases synopsis.

Last reviewed and updated: September 2026 · 2026–27 admissions

Our MD Medicine Thesis Guidance provides structured protocols, sample size formulas, and institutional review board (IRB) layout guides.

Acute Febrile Illness and Undifferentiated Fever

  1. Aetiological profile of acute undifferentiated febrile illness among adults admitted to a tertiary care teaching hospital in India: a hospital-based cross-sectional observational study.
  2. Clinical and laboratory profile of adults presenting with acute undifferentiated fever: a cross-sectional observational study.
  3. Association of thrombocytopenia with aetiology of acute febrile illness among hospitalised adults: a cross-sectional analytical study.
  4. Comparison of clinical features among dengue, malaria, enteric fever, and scrub typhus presenting as acute febrile illness: a cross-sectional comparative study.
  5. Association between duration of fever at presentation and laboratory abnormalities in adults with acute febrile illness: a cross-sectional analytical study.
  6. Diagnostic distribution of common infectious causes of acute fever during monsoon season in adults: a hospital-based cross-sectional study.
  7. Comparison of aetiological patterns of acute febrile illness during monsoon and non-monsoon periods: a cross-sectional comparative study.
  8. Association of leukopenia with specific etiologies of acute undifferentiated fever in adults: a cross-sectional analytical study.
  9. Association of leukocytosis with bacterial causes of acute febrile illness among hospitalised adults: a cross-sectional study.
  10. Clinical significance of relative bradycardia in adults presenting with acute febrile illness: a cross-sectional observational study.
  11. Association between elevated liver enzymes and aetiology of acute febrile illness: a cross-sectional analytical study.
  12. Comparison of liver function abnormalities among dengue, malaria, enteric fever, and scrub typhus: a cross-sectional comparative study.
  13. Prevalence of acute kidney injury at presentation among adults with acute infectious febrile illnesses: a cross-sectional observational study.
  14. Association of hyponatraemia with common infectious causes of acute febrile illness: a cross-sectional analytical study.
  15. Comparison of serum sodium levels among patients with dengue, malaria, enteric fever, and scrub typhus: a cross-sectional comparative study.
  16. Association of C-reactive protein levels with bacterial and non-bacterial causes of acute febrile illness: a cross-sectional analytical study.
  17. Comparison of neutrophil-to-lymphocyte ratio among common causes of acute undifferentiated fever: a cross-sectional comparative study.
  18. Association of platelet-to-lymphocyte ratio with severity of illness at presentation in acute febrile infections: a cross-sectional analytical study.
  19. Clinical and biochemical profile of acute febrile illness with thrombocytopenia in adults: a cross-sectional observational study.
  20. Aetiological spectrum of fever with thrombocytopenia among adults admitted to a tertiary care hospital: a cross-sectional study.
  21. Comparison of clinical characteristics of acute febrile illness with and without thrombocytopenia: a cross-sectional comparative study.
  22. Association between splenomegaly and infectious aetiology among adults with acute febrile illness: a cross-sectional analytical study.
  23. Aetiological profile of fever with hepatosplenomegaly among adult medical patients: a cross-sectional observational study.
  24. Association of rash with specific infectious causes of acute febrile illness: a cross-sectional analytical study.
  25. Clinical profile of acute febrile illness associated with rash in adults: a cross-sectional observational study.
  26. Aetiological pattern of fever with altered liver function tests among hospitalised adults: a cross-sectional study.
  27. Association between serum bilirubin elevation and common acute infectious diseases: a cross-sectional analytical study.
  28. Comparison of haematological abnormalities among common causes of acute undifferentiated fever: a cross-sectional comparative study.
  29. Relationship between body temperature at presentation and inflammatory markers among adults with acute infection: a cross-sectional analytical study.
  30. Prevalence and clinical significance of bicytopenia among adults with acute infectious febrile illnesses: a cross-sectional observational study.
  31. Aetiological profile of acute febrile illness with acute kidney injury among adults: a cross-sectional study.
  32. Association of hypotension at presentation with clinical and laboratory abnormalities in acute infectious diseases: a cross-sectional analytical study.
  33. Comparison of bedside clinical features for differentiating common tropical febrile illnesses in adults: a cross-sectional comparative study.
  34. Clinical and laboratory factors associated with severe presentation of acute undifferentiated febrile illness among adults: a hospital-based cross-sectional analytical study.

Dengue

  1. Clinical and laboratory profile of adults with laboratory-confirmed dengue infection: a cross-sectional observational study.
  2. Prevalence of thrombocytopenia and its severity among adults with dengue infection: a cross-sectional study.
  3. Association between platelet count and clinical severity of dengue at presentation: a cross-sectional analytical study.
  4. Relationship between haematocrit and severity classification in adults with dengue: a cross-sectional study.
  5. Comparison of haematological parameters between dengue with warning signs and dengue without warning signs: a cross-sectional comparative study.
  6. Association between leukopenia and clinical severity of dengue infection: a cross-sectional analytical study.
  7. Prevalence of liver enzyme elevation among adults with dengue infection: a cross-sectional observational study.
  8. Association between serum transaminase elevation and severity of dengue: a cross-sectional analytical study.
  9. Comparison of liver function abnormalities between patients with severe and non-severe dengue: a cross-sectional comparative study.
  10. Prevalence of acute kidney injury among adults hospitalised with dengue: a cross-sectional observational study.
  11. Association of acute kidney injury with thrombocytopenia and hemoconcentration in dengue: a cross-sectional analytical study.
  12. Prevalence of hyponatraemia among adults with dengue and its association with disease severity: a cross-sectional study.
  13. Comparison of serum sodium levels between dengue with and without warning signs: a cross-sectional comparative study.
  14. Association between serum albumin levels and severity of dengue at presentation: a cross-sectional analytical study.
  15. Prevalence of hypocalcaemia among adults with dengue and its relationship with clinical severity: a cross-sectional study.
  16. Association of C-reactive protein with severity of dengue infection: a cross-sectional analytical study.
  17. Comparison of neutrophil-to-lymphocyte ratio between severe and non-severe dengue: a cross-sectional comparative study.
  18. Relationship between platelet-to-lymphocyte ratio and dengue severity: a cross-sectional analytical study.
  19. Association between red cell distribution width and severe clinical presentation in dengue: a cross-sectional study.
  20. Comparison of mean platelet volume between patients with mild and severe dengue: a cross-sectional comparative study.
  21. Prevalence and pattern of bleeding manifestations among adults with dengue: a cross-sectional observational study.
  22. Association of platelet count with spontaneous bleeding manifestations in dengue: a cross-sectional analytical study.
  23. Comparison of clinical characteristics of dengue patients with and without bleeding manifestations: a cross-sectional comparative study.
  24. Prevalence of gallbladder wall oedema and ascites on ultrasonography among hospitalised adults with dengue: a cross-sectional study.
  25. Association between ultrasonographic plasma leakage markers and dengue severity: a cross-sectional analytical study.
  26. Prevalence of pleural effusion among hospitalised adults with dengue and its association with severity: a cross-sectional study.
  27. Clinical and biochemical profile of dengue infection in patients with type 2 diabetes mellitus: a cross-sectional observational study.
  28. Comparison of dengue severity between patients with and without type 2 diabetes mellitus: a cross-sectional comparative study.
  29. Comparison of dengue presentation in hypertensive and normotensive adults: a cross-sectional comparative study.
  30. Association of obesity with severe clinical presentation of dengue in adults: a cross-sectional analytical study.
  31. Comparison of dengue manifestations between younger and elderly adults: a cross-sectional comparative study.
  32. Clinical profile of dengue infection with marked transaminase elevation: a cross-sectional observational study.
  33. Association between thrombocytopenia and liver dysfunction among patients with dengue: a cross-sectional analytical study.
  34. Clinical, haematological, and biochemical factors associated with severe dengue at hospital presentation: a cross-sectional analytical study.

Respiratory Tract Infections and Community-Acquired Pneumonia

  1. Clinical and microbiological profile of community-acquired pneumonia among adults admitted to a tertiary care hospital: a cross-sectional observational study.
  2. Aetiological spectrum of community-acquired pneumonia in adult medical patients: a cross-sectional study.
  3. Association between age and severity of community-acquired pneumonia at presentation: a cross-sectional analytical study.
  4. Comparison of clinical features of community-acquired pneumonia in younger and elderly adults: a cross-sectional comparative study.
  5. Prevalence of type 2 diabetes mellitus among patients with community-acquired pneumonia and its association with severe presentation: a cross-sectional study.
  6. Comparison of clinical and laboratory features of community-acquired pneumonia in patients with and without type 2 diabetes mellitus: a cross-sectional comparative study.
  7. Association between hyperglycaemia at admission and severity of community-acquired pneumonia: a cross-sectional analytical study.
  8. Prevalence of hyponatraemia among adults with community-acquired pneumonia: a cross-sectional observational study.
  9. Association between hyponatraemia and severity of community-acquired pneumonia: a cross-sectional analytical study.
  10. Association of serum albumin levels with severity of community-acquired pneumonia: a cross-sectional study.
  11. Relationship between neutrophil-to-lymphocyte ratio and severity of community-acquired pneumonia: a cross-sectional analytical study.
  12. Comparison of neutrophil-to-lymphocyte ratio in mild and severe community-acquired pneumonia: a cross-sectional comparative study.
  13. Association between platelet-to-lymphocyte ratio and severity of community-acquired pneumonia: a cross-sectional analytical study.
  14. Association between red cell distribution width and severity of community-acquired pneumonia: a cross-sectional study.
  15. Relationship between C-reactive protein levels and radiological extent of community-acquired pneumonia: a cross-sectional analytical study.
  16. Comparison of clinical and laboratory parameters in lobar and multilobar pneumonia: a cross-sectional comparative study.
  17. Prevalence and pattern of radiological abnormalities in adults with community-acquired pneumonia: a cross-sectional observational study.
  18. Association between smoking and clinical severity of community-acquired pneumonia: a cross-sectional analytical study.
  19. Comparison of pneumonia presentation among smokers and non-smokers: a cross-sectional comparative study.
  20. Clinical and microbiological profile of pneumonia among patients with chronic obstructive pulmonary disease: a cross-sectional observational study.
  21. Comparison of pneumonia severity in patients with and without chronic obstructive pulmonary disease: a cross-sectional comparative study.
  22. Bacteriological profile and antimicrobial susceptibility pattern of sputum isolates in community-acquired pneumonia: a cross-sectional microbiological study.
  23. Prevalence of Gram-negative bacterial infection among adults with community-acquired pneumonia: a cross-sectional study.
  24. Clinical characteristics associated with Gram-negative community-acquired pneumonia: a cross-sectional analytical study.
  25. Comparison of bacterial and non-bacterial community-acquired pneumonia using routine clinical and laboratory parameters: a cross-sectional comparative study.
  26. Prevalence of acute kidney injury among adults with severe community-acquired pneumonia: a cross-sectional study.
  27. Association between renal dysfunction and severity of community-acquired pneumonia: a cross-sectional analytical study.
  28. Prevalence of thrombocytopenia among adults hospitalised with community-acquired pneumonia and its association with severe presentation: a cross-sectional study.
  29. Association between anaemia and severity of community-acquired pneumonia among adult inpatients: a cross-sectional analytical study.
  30. Clinical and laboratory profile of lower respiratory tract infection among elderly medical patients: a cross-sectional observational study.
  31. Comparison of lower respiratory tract infection in elderly patients with and without diabetes mellitus: a cross-sectional comparative study.
  32. Aetiological profile of acute lower respiratory tract infection among immunocompetent adults: a cross-sectional study.
  33. Association of multimorbidity with severe presentation of community-acquired pneumonia: a cross-sectional analytical study.
  34. Clinical, radiological, and laboratory factors associated with severe community-acquired pneumonia at admission: a cross-sectional analytical study.

Urinary Tract Infections

  1. Clinical and microbiological profile of urinary tract infection among adults admitted to a tertiary care hospital: a cross-sectional observational study.
  2. Bacteriological spectrum and antimicrobial susceptibility pattern of urinary isolates among adult patients with urinary tract infection: a cross-sectional study.
  3. Comparison of urinary tract infection among patients with and without type 2 diabetes mellitus: a cross-sectional comparative study.
  4. Prevalence of urinary tract infection among patients with type 2 diabetes mellitus presenting with urinary symptoms: a cross-sectional study.
  5. Association between glycaemic control and urinary tract infection among adults with type 2 diabetes mellitus: a cross-sectional analytical study.
  6. Comparison of microbiological patterns of urinary tract infection in diabetic and non-diabetic patients: a cross-sectional comparative study.
  7. Prevalence of asymptomatic bacteriuria among women with type 2 diabetes mellitus: a cross-sectional observational study.
  8. Clinical and microbiological profile of complicated urinary tract infection among adult medical patients: a cross-sectional study.
  9. Comparison of complicated and uncomplicated urinary tract infections in adult women: a cross-sectional comparative study.
  10. Association between age and multidrug-resistant urinary isolates in adults with urinary tract infection: a cross-sectional analytical study.
  11. Prevalence of multidrug-resistant organisms among urinary isolates in hospitalised adults: a cross-sectional microbiological study.
  12. Clinical factors associated with multidrug-resistant urinary tract infection: a cross-sectional analytical study.
  13. Comparison of urinary tract infections caused by multidrug-resistant and susceptible organisms: a cross-sectional comparative study.
  14. Prevalence and antimicrobial susceptibility pattern of Escherichia coli in adult urinary tract infections: a cross-sectional study.
  15. Prevalence and antimicrobial susceptibility pattern of Klebsiella species in adult urinary tract infections: a cross-sectional study.
  16. Comparison of Escherichia coli and Klebsiella urinary tract infections with respect to clinical and resistance profiles: a cross-sectional comparative study.
  17. Association between prior antibiotic exposure and resistant urinary isolates among adults: a cross-sectional analytical study.
  18. Association between recent hospitalisation and multidrug-resistant urinary tract infection: a cross-sectional analytical study.
  19. Clinical and microbiological profile of urinary tract infection in elderly adults: a cross-sectional observational study.
  20. Comparison of urinary tract infection patterns between younger and elderly adults: a cross-sectional comparative study.
  21. Prevalence of acute kidney injury among adults with complicated urinary tract infection: a cross-sectional study.
  22. Association between renal dysfunction and complicated urinary tract infection: a cross-sectional analytical study.
  23. Clinical profile of pyelonephritis among adults admitted to a tertiary care hospital: a cross-sectional observational study.
  24. Comparison of clinical and laboratory parameters in lower urinary tract infection and pyelonephritis: a cross-sectional comparative study.
  25. Association between leukocytosis and upper urinary tract involvement among adults with urinary infection: a cross-sectional analytical study.
  26. Association between C-reactive protein levels and clinical severity of urinary tract infection: a cross-sectional study.
  27. Relationship between neutrophil-to-lymphocyte ratio and complicated urinary tract infection: a cross-sectional analytical study.
  28. Prevalence of urinary tract infection among catheterized medical inpatients: a cross-sectional study.
  29. Microbiological profile of catheter-associated urinary tract infection among adult medical inpatients: a cross-sectional observational study.
  30. Comparison of antimicrobial resistance patterns in catheter-associated and non-catheter-associated urinary tract infections: a cross-sectional comparative study.
  31. Association between duration of catheterisation at evaluation and bacteriuria among hospitalised adults: a cross-sectional analytical study.
  32. Clinical factors associated with fungal urinary tract infection among hospitalised adults: a cross-sectional analytical study.
  33. Comparison of bacterial and fungal urinary tract infections among patients with diabetes mellitus: a cross-sectional comparative study.
  34. Clinical, laboratory, and microbiological factors associated with complicated urinary tract infection in adult medical patients: a cross-sectional analytical study.

Enteric Fever

  1. Clinical and laboratory profile of adults with culture-confirmed enteric fever: a cross-sectional observational study.
  2. Bacteriological profile and antimicrobial susceptibility pattern of Salmonella isolates in enteric fever: a cross-sectional microbiological study.
  3. Comparison of clinical characteristics of Salmonella Typhi and Salmonella Paratyphi infection in adults: a cross-sectional comparative study.
  4. Association between age and clinical severity of enteric fever at presentation: a cross-sectional analytical study.
  5. Prevalence of thrombocytopenia among adults with enteric fever: a cross-sectional study.
  6. Association between thrombocytopenia and clinical severity of enteric fever: a cross-sectional analytical study.
  7. Prevalence of leukopenia among adults with enteric fever and its association with clinical manifestations: a cross-sectional study.
  8. Comparison of haematological abnormalities in culture-positive and clinically suspected enteric fever: a cross-sectional comparative study.
  9. Prevalence of liver enzyme elevation among adults with enteric fever: a cross-sectional observational study.
  10. Association between transaminase elevation and severity of enteric fever: a cross-sectional analytical study.
  11. Comparison of liver function abnormalities in enteric fever and dengue: a cross-sectional comparative study.
  12. Association between splenomegaly and haematological abnormalities in enteric fever: a cross-sectional analytical study.
  13. Clinical significance of relative bradycardia among adults with enteric fever: a cross-sectional observational study.
  14. Comparison of pulse-temperature dissociation in enteric fever and other acute febrile illnesses: a cross-sectional comparative study.
  15. Prevalence of hyponatraemia among hospitalised adults with enteric fever: a cross-sectional study.
  16. Association between hyponatraemia and clinical severity of enteric fever: a cross-sectional analytical study.
  17. Association between serum albumin levels and severe clinical presentation of enteric fever: a cross-sectional study.
  18. Prevalence of acute kidney injury among adults with enteric fever: a cross-sectional observational study.
  19. Association between renal dysfunction and severe enteric fever: a cross-sectional analytical study.
  20. Relationship between C-reactive protein levels and clinical severity of enteric fever: a cross-sectional study.
  21. Comparison of neutrophil-to-lymphocyte ratio between enteric fever and dengue: a cross-sectional comparative study.
  22. Comparison of neutrophil-to-lymphocyte ratio between enteric fever and malaria: a cross-sectional comparative study.
  23. Association between platelet-to-lymphocyte ratio and severity of enteric fever: a cross-sectional analytical study.
  24. Antimicrobial resistance pattern of enteric fever isolates among adults attending a tertiary care hospital: a cross-sectional study.
  25. Prevalence of fluoroquinolone non-susceptibility among Salmonella isolates in enteric fever: a cross-sectional microbiological study.
  26. Prevalence of multidrug-resistant Salmonella among culture-confirmed enteric fever cases: a cross-sectional study.
  27. Clinical characteristics associated with resistant enteric fever isolates: a cross-sectional analytical study.
  28. Comparison of laboratory abnormalities between antimicrobial-susceptible and antimicrobial-resistant enteric fever: a cross-sectional comparative study.
  29. Association of prior antibiotic exposure with blood culture positivity among clinically suspected enteric fever cases: a cross-sectional analytical study.
  30. Comparison of clinical and laboratory findings between blood culture-positive and culture-negative suspected enteric fever: a cross-sectional comparative study.
  31. Diagnostic agreement between commonly used serological testing and blood culture in suspected enteric fever: a cross-sectional diagnostic study.
  32. Clinical utility of routine haematological parameters for differentiating enteric fever from dengue: a cross-sectional comparative study.
  33. Clinical utility of routine haematological parameters for differentiating enteric fever from malaria: a cross-sectional comparative study.
  34. Clinical and laboratory factors associated with severe presentation of enteric fever among hospitalised adults: a cross-sectional analytical study.

Tuberculosis

  1. Clinical and demographic profile of pulmonary tuberculosis among adults admitted to a tertiary care medical unit: a cross-sectional observational study.
  2. Association between nutritional status and severity of pulmonary tuberculosis at presentation: a cross-sectional analytical study.
  3. Prevalence of undernutrition among adults with pulmonary tuberculosis: a cross-sectional study.
  4. Comparison of clinical and radiological findings in undernourished and normally nourished patients with pulmonary tuberculosis: a cross-sectional comparative study.
  5. Prevalence of type 2 diabetes mellitus among adults with pulmonary tuberculosis: a cross-sectional observational study.
  6. Comparison of pulmonary tuberculosis presentation in patients with and without type 2 diabetes mellitus: a cross-sectional comparative study.
  7. Association between glycaemic control and radiological extent of pulmonary tuberculosis among patients with diabetes mellitus: a cross-sectional analytical study.
  8. Comparison of sputum bacillary burden among pulmonary tuberculosis patients with and without diabetes mellitus: a cross-sectional comparative study.
  9. Association between smoking and radiological severity of pulmonary tuberculosis: a cross-sectional analytical study.
  10. Comparison of clinical presentation of pulmonary tuberculosis in smokers and non-smokers: a cross-sectional comparative study.
  11. Prevalence of anaemia among adults with pulmonary tuberculosis and its association with disease severity: a cross-sectional study.
  12. Relationship between haemoglobin concentration and radiological extent of pulmonary tuberculosis: a cross-sectional analytical study.
  13. Association between serum albumin and severity of pulmonary tuberculosis: a cross-sectional study.
  14. Comparison of serum albumin levels in sputum-positive and sputum-negative pulmonary tuberculosis: a cross-sectional comparative study.
  15. Relationship between neutrophil-to-lymphocyte ratio and radiological severity of pulmonary tuberculosis: a cross-sectional analytical study.
  16. Association between platelet-to-lymphocyte ratio and sputum bacillary burden in pulmonary tuberculosis: a cross-sectional study.
  17. Prevalence of hyponatraemia among adults with tuberculosis admitted to medical wards: a cross-sectional observational study.
  18. Association between hyponatraemia and extrapulmonary tuberculosis: a cross-sectional analytical study.
  19. Clinical profile of extrapulmonary tuberculosis among adults admitted under General Medicine: a cross-sectional observational study.
  20. Distribution of extrapulmonary tuberculosis sites among adult medical patients: a cross-sectional study.
  21. Comparison of clinical and laboratory profiles of pulmonary and extrapulmonary tuberculosis: a cross-sectional comparative study.
  22. Clinical profile of tuberculous pleural effusion among adults: a cross-sectional observational study.
  23. Comparison of pleural fluid characteristics in tuberculous and non-tuberculous exudative pleural effusions: a cross-sectional comparative study.
  24. Association between pleural fluid lymphocyte proportion and tuberculous pleural effusion: a cross-sectional analytical study.
  25. Clinical and laboratory profile of abdominal tuberculosis among adults: a cross-sectional observational study.
  26. Comparison of abdominal tuberculosis and other causes of ascites using routine clinical and biochemical parameters: a cross-sectional comparative study.
  27. Prevalence of human immunodeficiency virus infection among adults diagnosed with tuberculosis: a cross-sectional study.
  28. Comparison of tuberculosis presentation in patients with and without human immunodeficiency virus infection: a cross-sectional comparative study.
  29. Association of low body mass index with extrapulmonary tuberculosis: a cross-sectional analytical study.
  30. Comparison of chest radiographic patterns in pulmonary tuberculosis with and without diabetes mellitus: a cross-sectional comparative study.
  31. Association between leucocyte indices and radiological extent of pulmonary tuberculosis: a cross-sectional analytical study.
  32. Clinical and biochemical factors associated with extensive pulmonary tuberculosis at presentation: a cross-sectional analytical study.
  33. Spectrum of comorbidities among adults with tuberculosis attending a tertiary care hospital: a cross-sectional observational study.

Malaria

  1. Clinical and laboratory profile of adults with malaria admitted to a tertiary care hospital: a cross-sectional observational study.
  2. Comparison of Plasmodium vivax and Plasmodium falciparum malaria in adults: a cross-sectional comparative study.
  3. Prevalence and severity of thrombocytopenia among adults with malaria: a cross-sectional study.
  4. Association between platelet count and severe malaria at presentation: a cross-sectional analytical study.
  5. Comparison of thrombocytopenia in Plasmodium vivax and Plasmodium falciparum malaria: a cross-sectional comparative study.
  6. Prevalence of anaemia among adults with malaria and its association with parasite species: a cross-sectional study.
  7. Comparison of haemoglobin levels in Plasmodium vivax and Plasmodium falciparum malaria: a cross-sectional comparative study.
  8. Prevalence of jaundice among adults with malaria and its association with severe disease: a cross-sectional study.
  9. Association between serum bilirubin and severe malaria: a cross-sectional analytical study.
  10. Comparison of liver function abnormalities between Plasmodium vivax and Plasmodium falciparum malaria: a cross-sectional comparative study.
  11. Prevalence of acute kidney injury among adults with malaria: a cross-sectional observational study.
  12. Association between acute kidney injury and severe malaria at presentation: a cross-sectional analytical study.
  13. Comparison of renal function abnormalities in Plasmodium vivax and Plasmodium falciparum malaria: a cross-sectional comparative study.
  14. Prevalence of hyponatraemia among adults with malaria: a cross-sectional study.
  15. Association between serum sodium levels and severe malaria: a cross-sectional analytical study.
  16. Comparison of electrolyte abnormalities in Plasmodium vivax and Plasmodium falciparum malaria: a cross-sectional comparative study.
  17. Association between blood glucose abnormalities and severe malaria among adults: a cross-sectional study.
  18. Relationship between C-reactive protein levels and severity of malaria: a cross-sectional analytical study.
  19. Comparison of neutrophil-to-lymphocyte ratio in severe and non-severe malaria: a cross-sectional comparative study.
  20. Association between platelet-to-lymphocyte ratio and severe malaria: a cross-sectional analytical study.
  21. Association between red cell distribution width and severe clinical presentation of malaria: a cross-sectional study.
  22. Comparison of haematological parameters between malaria and dengue: a cross-sectional comparative study.
  23. Comparison of liver function tests between malaria and dengue: a cross-sectional comparative study.
  24. Comparison of acute kidney injury patterns in malaria and dengue: a cross-sectional comparative study.
  25. Clinical profile of malaria with severe thrombocytopenia among adults: a cross-sectional observational study.
  26. Association between splenomegaly and haematological abnormalities in malaria: a cross-sectional analytical study.
  27. Prevalence of mixed-species malaria among adults diagnosed at a tertiary care hospital: a cross-sectional study.
  28. Comparison of mixed-species malaria and mono-infection with respect to clinical severity: a cross-sectional comparative study.
  29. Prevalence of severe manifestations among adults with Plasmodium vivax malaria: a cross-sectional observational study.
  30. Comparison of severe manifestations of Plasmodium vivax and Plasmodium falciparum malaria: a cross-sectional comparative study.
  31. Association of diabetes mellitus with severe presentation of malaria among adults: a cross-sectional analytical study.
  32. Comparison of malaria presentation in patients with and without diabetes mellitus: a cross-sectional comparative study.
  33. Clinical and laboratory factors associated with severe malaria at hospital admission: a cross-sectional analytical study.

Sepsis and Bloodstream Infections

  1. Clinical and microbiological profile of sepsis among adult medical inpatients: a cross-sectional observational study.
  2. Aetiological spectrum of sepsis among adults admitted to a tertiary care hospital: a cross-sectional study.
  3. Comparison of clinical and laboratory profiles of culture-positive and culture-negative sepsis: a cross-sectional comparative study.
  4. Spectrum and antimicrobial susceptibility pattern of organisms isolated from blood cultures in adult sepsis: a cross-sectional microbiological study.
  5. Prevalence of Gram-negative bacteraemia among adults with sepsis: a cross-sectional observational study.
  6. Comparison of Gram-positive and Gram-negative bloodstream infections among adult medical patients: a cross-sectional comparative study.
  7. Clinical factors associated with Gram-negative sepsis among hospitalised adults: a cross-sectional analytical study.
  8. Prevalence of multidrug-resistant bloodstream infection among adults with sepsis: a cross-sectional study.
  9. Association between prior hospitalisation and multidrug-resistant bloodstream infection: a cross-sectional analytical study.
  10. Association between prior antibiotic exposure and multidrug-resistant bloodstream infection: a cross-sectional analytical study.
  11. Comparison of laboratory parameters between multidrug-resistant and susceptible bloodstream infections: a cross-sectional comparative study.
  12. Association between lactate level at presentation and severity of sepsis: a cross-sectional analytical study.
  13. Relationship between platelet count and severity of sepsis at presentation: a cross-sectional study.
  14. Prevalence of thrombocytopenia among adult patients with sepsis: a cross-sectional observational study.
  15. Association between neutrophil-to-lymphocyte ratio and severity of sepsis: a cross-sectional analytical study.
  16. Comparison of neutrophil-to-lymphocyte ratio in sepsis and non-infectious systemic inflammatory conditions: a cross-sectional comparative study.
  17. Association between platelet-to-lymphocyte ratio and severity of sepsis: a cross-sectional study.
  18. Relationship between red cell distribution width and severity of sepsis among adults: a cross-sectional analytical study.
  19. Association between serum albumin levels and severe sepsis: a cross-sectional study.
  20. Comparison of serum albumin levels in culture-positive and culture-negative sepsis: a cross-sectional comparative study.
  21. Prevalence of acute kidney injury among adult patients with sepsis: a cross-sectional observational study.
  22. Association between renal dysfunction and severity of sepsis at presentation: a cross-sectional analytical study.
  23. Prevalence of hyponatraemia among adults with sepsis and its association with clinical severity: a cross-sectional study.
  24. Association between hyperglycaemia at admission and severe sepsis among adults without known diabetes mellitus: a cross-sectional analytical study.
  25. Clinical and microbiological profile of sepsis among patients with type 2 diabetes mellitus: a cross-sectional observational study.
  26. Comparison of sepsis presentation in diabetic and non-diabetic adults: a cross-sectional comparative study.
  27. Distribution of primary infection sources among adults presenting with sepsis: a cross-sectional study.
  28. Comparison of pulmonary and urinary sources of sepsis with respect to clinical and laboratory parameters: a cross-sectional comparative study.
  29. Clinical profile of elderly patients presenting with sepsis: a cross-sectional observational study.
  30. Comparison of sepsis presentation in elderly and younger adults: a cross-sectional comparative study.
  31. Association between multimorbidity and severe sepsis at presentation: a cross-sectional analytical study.
  32. Relationship between simple bedside severity scores and laboratory markers among adults with sepsis: a cross-sectional analytical study.
  33. Clinical, laboratory, and microbiological factors associated with severe sepsis at hospital presentation: a cross-sectional analytical study.

Human Immunodeficiency Virus Infection and Opportunistic Infections

  1. Clinical profile of adults newly diagnosed with human immunodeficiency virus infection at a tertiary care hospital: a cross-sectional observational study.
  2. Spectrum of opportunistic infections among adults with human immunodeficiency virus infection: a cross-sectional study.
  3. Association between cluster of differentiation 4 cell count and pattern of opportunistic infections: a cross-sectional analytical study.
  4. Comparison of opportunistic infection patterns across different cluster of differentiation 4 cell count categories: a cross-sectional comparative study.
  5. Prevalence of tuberculosis among adults with human immunodeficiency virus infection: a cross-sectional observational study.
  6. Comparison of tuberculosis presentation in human immunodeficiency virus-positive and human immunodeficiency virus-negative adults: a cross-sectional comparative study.
  7. Clinical profile of pulmonary tuberculosis among adults with human immunodeficiency virus infection: a cross-sectional observational study.
  8. Clinical profile of extrapulmonary tuberculosis among adults with human immunodeficiency virus infection: a cross-sectional observational study.
  9. Association between low cluster of differentiation 4 cell count and extrapulmonary tuberculosis: a cross-sectional analytical study.
  10. Prevalence of oral candidiasis among adults with human immunodeficiency virus infection: a cross-sectional study.
  11. Association between oral candidiasis and cluster of differentiation 4 cell count: a cross-sectional analytical study.
  12. Prevalence of chronic diarrhoea among adults with human immunodeficiency virus infection: a cross-sectional observational study.
  13. Aetiological profile of chronic diarrhoea among adults with human immunodeficiency virus infection: a cross-sectional study.
  14. Association between anaemia and cluster of differentiation 4 cell count in adults with human immunodeficiency virus infection: a cross-sectional analytical study.
  15. Prevalence and pattern of anaemia among adults with human immunodeficiency virus infection: a cross-sectional observational study.
  16. Prevalence of leukopenia and thrombocytopenia among adults with human immunodeficiency virus infection: a cross-sectional study.
  17. Association between cytopenias and advanced human immunodeficiency virus disease: a cross-sectional analytical study.
  18. Prevalence of liver function abnormalities among adults with human immunodeficiency virus infection: a cross-sectional observational study.
  19. Association between liver enzyme abnormalities and antiretroviral treatment pattern among adults with human immunodeficiency virus infection: a cross-sectional analytical study.
  20. Prevalence of renal dysfunction among adults with human immunodeficiency virus infection: a cross-sectional study.
  21. Association between renal dysfunction and current antiretroviral regimen in adults with human immunodeficiency virus infection: a cross-sectional analytical study.
  22. Prevalence of dyslipidaemia among adults receiving antiretroviral therapy: a cross-sectional observational study.
  23. Comparison of lipid profiles across commonly used antiretroviral regimens: a cross-sectional comparative study.
  24. Prevalence of type 2 diabetes mellitus among adults receiving antiretroviral therapy: a cross-sectional study.
  25. Association between body mass index and metabolic abnormalities among adults with human immunodeficiency virus infection: a cross-sectional analytical study.
  26. Prevalence of hepatitis B virus coinfection among adults with human immunodeficiency virus infection: a cross-sectional study.
  27. Prevalence of hepatitis C virus coinfection among adults with human immunodeficiency virus infection: a cross-sectional study.
  28. Comparison of liver function parameters in human immunodeficiency virus infection with and without viral hepatitis coinfection: a cross-sectional comparative study.
  29. Prevalence of skin manifestations among adults with human immunodeficiency virus infection: a cross-sectional observational study.
  30. Association between mucocutaneous manifestations and cluster of differentiation 4 cell count: a cross-sectional analytical study.
  31. Clinical and laboratory profile of hospitalised adults with advanced human immunodeficiency virus disease: a cross-sectional observational study.
  32. Comparison of clinical profiles of treatment-naive and treatment-experienced adults with human immunodeficiency virus infection: a cross-sectional comparative study.
  33. Association between nutritional status and advanced human immunodeficiency virus disease: a cross-sectional analytical study.

Central Nervous System Infections

  1. Clinical and aetiological profile of acute meningitis among adults admitted to a tertiary care hospital: a cross-sectional observational study.
  2. Comparison of clinical and cerebrospinal fluid findings in bacterial and viral meningitis among adults: a cross-sectional comparative study.
  3. Clinical and cerebrospinal fluid profile of tuberculous meningitis among adults: a cross-sectional observational study.
  4. Comparison of cerebrospinal fluid parameters in tuberculous and bacterial meningitis: a cross-sectional comparative study.
  5. Association between cerebrospinal fluid protein concentration and clinical severity of meningitis: a cross-sectional analytical study.
  6. Association between cerebrospinal fluid glucose levels and aetiology of meningitis: a cross-sectional analytical study.
  7. Diagnostic value of cerebrospinal fluid cell differential in common causes of meningitis: a cross-sectional analytical study.
  8. Clinical and laboratory profile of acute meningoencephalitis among adults: a cross-sectional observational study.
  9. Aetiological spectrum of acute encephalitis syndrome among adult medical patients: a cross-sectional study.
  10. Prevalence of seizures among adults with central nervous system infections: a cross-sectional observational study.
  11. Association between seizures and cerebrospinal fluid abnormalities in meningitis and encephalitis: a cross-sectional analytical study.
  12. Prevalence of hyponatraemia among adults with central nervous system infections: a cross-sectional study.
  13. Association between hyponatraemia and severity of central nervous system infections: a cross-sectional analytical study.
  14. Comparison of serum sodium abnormalities in tuberculous meningitis and acute bacterial meningitis: a cross-sectional comparative study.
  15. Prevalence of altered sensorium among adults with meningitis and its association with cerebrospinal fluid findings: a cross-sectional study.
  16. Association between Glasgow Coma Scale score and laboratory abnormalities in adult meningitis: a cross-sectional analytical study.
  17. Comparison of clinical presentation of meningitis in younger and elderly adults: a cross-sectional comparative study.
  18. Clinical profile of cryptococcal meningitis among adults with human immunodeficiency virus infection: a cross-sectional observational study.
  19. Association between cluster of differentiation 4 cell count and cryptococcal meningitis among adults with human immunodeficiency virus infection: a cross-sectional analytical study.
  20. Comparison of cerebrospinal fluid profiles of cryptococcal and tuberculous meningitis in human immunodeficiency virus infection: a cross-sectional comparative study.
  21. Prevalence of human immunodeficiency virus infection among adults presenting with meningitis: a cross-sectional study.
  22. Association between diabetes mellitus and bacterial meningitis among adults: a cross-sectional analytical study.
  23. Comparison of bacterial meningitis presentation in patients with and without diabetes mellitus: a cross-sectional comparative study.
  24. Clinical and radiological profile of brain abscess among adults admitted under General Medicine: a cross-sectional observational study.
  25. Aetiological pattern of brain abscess among adult patients: a cross-sectional study.
  26. Association between source of infection and location of brain abscess: a cross-sectional analytical study.
  27. Clinical profile of neurotuberculosis among adults: a cross-sectional observational study.
  28. Comparison of tuberculous meningitis with intracranial tuberculoma regarding clinical and laboratory features: a cross-sectional comparative study.
  29. Prevalence of cranial nerve involvement among adults with tuberculous meningitis: a cross-sectional study.
  30. Association between cranial nerve involvement and cerebrospinal fluid abnormalities in tuberculous meningitis: a cross-sectional analytical study.
  31. Prevalence of acute kidney injury among adults with severe central nervous system infections: a cross-sectional observational study.
  32. Association between inflammatory markers and severe presentation of meningitis among adults: a cross-sectional analytical study.
  33. Clinical, cerebrospinal fluid, and laboratory factors associated with severe presentation of adult meningitis: a cross-sectional analytical study.

Acute Gastroenteritis and Gastrointestinal Infections

  1. Clinical and aetiological profile of acute infectious diarrhoea among adults admitted to a tertiary care hospital: a cross-sectional observational study.
  2. Microbiological spectrum of acute gastroenteritis among adult medical patients: a cross-sectional study.
  3. Comparison of clinical features of bacterial and non-bacterial acute gastroenteritis: a cross-sectional comparative study.
  4. Prevalence of dehydration among adults with acute gastroenteritis and its association with electrolyte abnormalities: a cross-sectional study.
  5. Association between serum sodium abnormalities and severity of dehydration in acute gastroenteritis: a cross-sectional analytical study.
  6. Prevalence of hypokalaemia among adults with acute gastroenteritis: a cross-sectional observational study.
  7. Association between hypokalaemia and electrocardiographic abnormalities in adults with acute gastroenteritis: a cross-sectional analytical study.
  8. Prevalence of acute kidney injury among adults admitted with acute gastroenteritis: a cross-sectional study.
  9. Association between dehydration and acute kidney injury in adults with acute gastroenteritis: a cross-sectional analytical study.
  10. Comparison of clinical and laboratory parameters in patients with and without acute kidney injury during acute gastroenteritis: a cross-sectional comparative study.
  11. Prevalence of leukocytosis among adults with infectious diarrhoea and its association with bacterial aetiology: a cross-sectional study.
  12. Relationship between C-reactive protein and bacterial acute gastroenteritis: a cross-sectional analytical study.
  13. Clinical profile of dysentery among adult patients: a cross-sectional observational study.
  14. Microbiological profile of acute dysentery among adults: a cross-sectional study.
  15. Comparison of dysenteric and non-dysenteric acute diarrhoea regarding clinical and laboratory parameters: a cross-sectional comparative study.
  16. Prevalence of antibiotic use before hospital presentation among adults with acute gastroenteritis: a cross-sectional observational study.
  17. Association between prior antibiotic use and stool culture positivity in acute infectious diarrhoea: a cross-sectional analytical study.
  18. Clinical and microbiological profile of acute gastroenteritis among elderly adults: a cross-sectional observational study.
  19. Comparison of acute gastroenteritis in elderly and younger adults: a cross-sectional comparative study.
  20. Association between diabetes mellitus and severe dehydration in acute gastroenteritis: a cross-sectional analytical study.
  21. Comparison of electrolyte abnormalities in diabetic and non-diabetic adults with acute gastroenteritis: a cross-sectional comparative study.
  22. Clinical profile of food-borne acute gastroenteritis outbreaks presenting to a tertiary care hospital: a cross-sectional observational study.
  23. Association between food consumption history and clinical pattern of acute gastroenteritis: a cross-sectional analytical study.
  24. Prevalence of fever among adults with acute infectious diarrhoea and its association with bacterial aetiology: a cross-sectional study.
  25. Relationship between stool microscopy findings and bacterial stool culture in acute gastroenteritis: a cross-sectional diagnostic study.
  26. Prevalence of intestinal parasitic infection among adults presenting with chronic or recurrent diarrhoea: a cross-sectional study.
  27. Comparison of clinical characteristics of parasitic and non-parasitic diarrhoea among adults: a cross-sectional comparative study.
  28. Prevalence of intestinal parasitic infection among adults with human immunodeficiency virus infection and diarrhoea: a cross-sectional study.
  29. Association between immunosuppression and intestinal parasitic infections in human immunodeficiency virus-positive adults: a cross-sectional analytical study.
  30. Clinical and laboratory profile of infectious colitis among adults: a cross-sectional observational study.
  31. Prevalence of Clostridioides difficile infection among hospitalised adults with antibiotic-associated diarrhoea: a cross-sectional study.
  32. Clinical factors associated with Clostridioides difficile infection among adults with hospital-associated diarrhoea: a cross-sectional analytical study.
  33. Clinical, electrolyte, and renal abnormalities associated with severe acute infectious gastroenteritis among adults: a cross-sectional analytical study.

Viral Hepatitis and Infectious Liver Disease

  1. Clinical and biochemical profile of acute viral hepatitis among adults admitted to a tertiary care hospital: a cross-sectional observational study.
  2. Aetiological distribution of acute viral hepatitis among adult medical patients: a cross-sectional study.
  3. Comparison of clinical and biochemical profiles of hepatitis A and hepatitis E infections in adults: a cross-sectional comparative study.
  4. Association between serum bilirubin levels and severity of acute viral hepatitis at presentation: a cross-sectional analytical study.
  5. Relationship between serum transaminase levels and clinical manifestations of acute viral hepatitis: a cross-sectional study.
  6. Prevalence of coagulopathy among adults with acute viral hepatitis: a cross-sectional observational study.
  7. Association between prolonged prothrombin time and severe presentation of acute viral hepatitis: a cross-sectional analytical study.
  8. Prevalence of thrombocytopenia among adults with acute viral hepatitis: a cross-sectional study.
  9. Association between platelet count and biochemical severity of acute viral hepatitis: a cross-sectional analytical study.
  10. Prevalence of acute kidney injury among adults with acute viral hepatitis: a cross-sectional observational study.
  11. Association between renal dysfunction and severe acute viral hepatitis: a cross-sectional analytical study.
  12. Comparison of acute hepatitis E infection in younger and elderly adults: a cross-sectional comparative study.
  13. Clinical and biochemical profile of acute hepatitis E infection among adults: a cross-sectional observational study.
  14. Comparison of hepatitis E and hepatitis A infections regarding haematological and biochemical abnormalities: a cross-sectional comparative study.
  15. Prevalence of hepatitis B surface antigen positivity among adult medical inpatients: a cross-sectional study.
  16. Clinical and biochemical profile of newly detected hepatitis B virus infection among adults: a cross-sectional observational study.
  17. Association between hepatitis B virus infection and liver enzyme abnormalities among asymptomatic adults: a cross-sectional analytical study.
  18. Prevalence of hepatitis C virus infection among adults attending a tertiary care medicine department: a cross-sectional study.
  19. Clinical and biochemical profile of newly detected hepatitis C virus infection among adults: a cross-sectional observational study.
  20. Comparison of biochemical liver profiles in hepatitis B and hepatitis C virus infections: a cross-sectional comparative study.
  21. Prevalence of hepatitis B virus infection among patients with type 2 diabetes mellitus: a cross-sectional study.
  22. Prevalence of hepatitis C virus infection among patients with type 2 diabetes mellitus: a cross-sectional study.
  23. Comparison of metabolic profiles of patients with type 2 diabetes mellitus with and without hepatitis C virus infection: a cross-sectional comparative study.
  24. Prevalence of hepatitis B and hepatitis C coinfection among adults with human immunodeficiency virus infection: a cross-sectional study.
  25. Comparison of liver function parameters in human immunodeficiency virus infection with and without hepatitis virus coinfection: a cross-sectional comparative study.
  26. Association between thrombocytopenia and chronic viral hepatitis among adults: a cross-sectional analytical study.
  27. Relationship between serum albumin levels and chronic viral hepatitis-related liver dysfunction: a cross-sectional analytical study.
  28. Comparison of non-invasive laboratory indices of liver fibrosis among adults with chronic hepatitis B and hepatitis C infections: a cross-sectional comparative study.
  29. Association between age and non-invasive fibrosis indices among patients with chronic viral hepatitis: a cross-sectional analytical study.
  30. Prevalence of fatty liver on ultrasonography among adults with chronic hepatitis B infection: a cross-sectional study.
  31. Comparison of metabolic risk factors in chronic hepatitis B infection with and without fatty liver: a cross-sectional comparative study.
  32. Clinical and laboratory profile of febrile jaundice among adult medical patients: a cross-sectional observational study.
  33. Aetiological spectrum of acute febrile illness with jaundice among adults admitted to a tertiary care hospital: a cross-sectional study.

Skin, Soft-Tissue and Common Focal Bacterial Infections

  1. Clinical and microbiological profile of cellulitis among adults admitted to a tertiary care hospital: a cross-sectional observational study.
  2. Bacteriological spectrum and antimicrobial susceptibility pattern of skin and soft-tissue infections among adults: a cross-sectional study.
  3. Comparison of cellulitis in patients with and without type 2 diabetes mellitus: a cross-sectional comparative study.
  4. Association between glycaemic control and severity of cellulitis among patients with type 2 diabetes mellitus: a cross-sectional analytical study.
  5. Prevalence of lower-limb cellulitis among adults with diabetes mellitus: a cross-sectional study.
  6. Clinical and microbiological profile of diabetic foot infection among adult medical patients: a cross-sectional observational study.
  7. Bacterial spectrum and antimicrobial susceptibility pattern in diabetic foot infections: a cross-sectional microbiological study.
  8. Prevalence of multidrug-resistant organisms in diabetic foot infections: a cross-sectional study.
  9. Clinical factors associated with multidrug-resistant diabetic foot infection: a cross-sectional analytical study.
  10. Comparison of clinical and microbiological characteristics of mild and severe diabetic foot infections: a cross-sectional comparative study.
  11. Association between glycated haemoglobin and severity of diabetic foot infection: a cross-sectional analytical study.
  12. Association between peripheral neuropathy and severity of diabetic foot infection: a cross-sectional study.
  13. Association between peripheral arterial disease and diabetic foot infection severity: a cross-sectional analytical study.
  14. Comparison of microbiological profiles of neuropathic and ischaemic diabetic foot infections: a cross-sectional comparative study.
  15. Prevalence of osteomyelitis among adults with diabetic foot infection at presentation: a cross-sectional study.
  16. Association between inflammatory markers and underlying osteomyelitis in diabetic foot infection: a cross-sectional analytical study.
  17. Clinical and bacteriological profile of abscesses among adult medical patients: a cross-sectional observational study.
  18. Prevalence of methicillin-resistant Staphylococcus aureus among skin and soft-tissue infection isolates: a cross-sectional microbiological study.
  19. Comparison of methicillin-resistant and methicillin-sensitive Staphylococcus aureus skin infections: a cross-sectional comparative study.
  20. Clinical factors associated with methicillin-resistant Staphylococcus aureus skin and soft-tissue infection: a cross-sectional analytical study.
  21. Clinical and microbiological profile of infected pressure ulcers among bedridden medical patients: a cross-sectional observational study.
  22. Prevalence of multidrug-resistant organisms in infected pressure ulcers: a cross-sectional study.
  23. Association between diabetes mellitus and infected pressure ulcers among bedridden adults: a cross-sectional analytical study.
  24. Clinical profile of erysipelas among adults attending a tertiary care hospital: a cross-sectional observational study.
  25. Comparison of recurrent self-reported and first-episode cellulitis with respect to predisposing factors: a cross-sectional comparative study.
  26. Association between obesity and lower-limb cellulitis among adults: a cross-sectional analytical study.
  27. Association between chronic oedema and lower-limb cellulitis: a cross-sectional study.
  28. Association between tinea pedis and lower-limb cellulitis among adults: a cross-sectional analytical study.
  29. Clinical profile of parotid and salivary gland bacterial infections among adult medical patients: a cross-sectional observational study.
  30. Clinical and microbiological profile of pyomyositis among adults: a cross-sectional observational study.
  31. Association between diabetes mellitus and pyomyositis among adults: a cross-sectional analytical study.
  32. Comparison of skin and soft-tissue infections in younger and elderly adults: a cross-sectional comparative study.
  33. Clinical, metabolic, and microbiological factors associated with severe skin and soft-tissue infection among adult medical patients: a cross-sectional analytical study.

Scrub Typhus, Leptospirosis and Other Zoonotic or Vector-Borne Infections

  1. Clinical and laboratory profile of scrub typhus among adults admitted to a tertiary care hospital: a cross-sectional observational study.
  2. Prevalence of thrombocytopenia among adults with scrub typhus: a cross-sectional study.
  3. Association between thrombocytopenia and severe clinical presentation of scrub typhus: a cross-sectional analytical study.
  4. Prevalence of liver dysfunction among adults with scrub typhus: a cross-sectional observational study.
  5. Association between transaminase elevation and severity of scrub typhus: a cross-sectional analytical study.
  6. Prevalence of acute kidney injury among adults with scrub typhus: a cross-sectional study.
  7. Association between renal dysfunction and severe scrub typhus: a cross-sectional analytical study.
  8. Prevalence of hyponatraemia among adults with scrub typhus and its association with severe presentation: a cross-sectional study.
  9. Comparison of clinical and laboratory features of scrub typhus and dengue: a cross-sectional comparative study.
  10. Comparison of scrub typhus and enteric fever using routine haematological and biochemical parameters: a cross-sectional comparative study.
  11. Comparison of scrub typhus and malaria with respect to clinical and laboratory features: a cross-sectional comparative study.
  12. Association between eschar presence and clinical severity of scrub typhus: a cross-sectional analytical study.
  13. Prevalence and distribution of eschar sites among adults with scrub typhus: a cross-sectional observational study.
  14. Clinical and laboratory factors associated with severe scrub typhus at presentation: a cross-sectional analytical study.
  15. Clinical and laboratory profile of leptospirosis among adults admitted to a tertiary care hospital: a cross-sectional observational study.
  16. Prevalence of acute kidney injury among adults with leptospirosis: a cross-sectional study.
  17. Association between jaundice and renal dysfunction among patients with leptospirosis: a cross-sectional analytical study.
  18. Prevalence of thrombocytopenia among adults with leptospirosis: a cross-sectional observational study.
  19. Association between platelet count and severe presentation of leptospirosis: a cross-sectional analytical study.
  20. Comparison of leptospirosis and dengue among adults presenting with fever and thrombocytopenia: a cross-sectional comparative study.
  21. Comparison of leptospirosis and malaria among adults presenting with fever, jaundice, and renal dysfunction: a cross-sectional comparative study.
  22. Clinical profile of adults presenting with suspected zoonotic febrile illness following occupational exposure: a cross-sectional observational study.
  23. Association between agricultural occupation and scrub typhus among adults with acute undifferentiated fever: a cross-sectional analytical study.
  24. Association between animal exposure and leptospirosis among adults with acute febrile illness: a cross-sectional analytical study.
  25. Clinical profile of brucellosis among adults diagnosed at a tertiary care hospital: a cross-sectional observational study.
  26. Prevalence of musculoskeletal manifestations among adults with brucellosis: a cross-sectional study.
  27. Association between occupational animal exposure and brucellosis among adults with prolonged fever: a cross-sectional analytical study.
  28. Comparison of brucellosis and tuberculosis among adults presenting with prolonged fever: a cross-sectional comparative study.
  29. Aetiological profile of prolonged fever among adult patients admitted to General Medicine: a cross-sectional observational study.
  30. Contribution of tuberculosis, brucellosis, human immunodeficiency virus infection, and occult bacterial infection to prolonged fever in adults: a cross-sectional study.
  31. Association between splenomegaly and infectious causes of prolonged fever: a cross-sectional analytical study.
  32. Comparison of haematological parameters among common zoonotic and vector-borne febrile illnesses: a cross-sectional comparative study.
  33. Clinical and laboratory factors associated with zoonotic or vector-borne aetiology among adults with acute undifferentiated fever: a cross-sectional analytical study.

Antimicrobial Resistance, Hospital-Acquired Infections and Antibiotic Use

  1. Prevalence and pattern of antimicrobial resistance among bacterial isolates from adult medical inpatients: a cross-sectional microbiological study.
  2. Distribution of multidrug-resistant organisms among urine, blood, sputum, and wound isolates in adult medical patients: a cross-sectional study.
  3. Comparison of antimicrobial resistance patterns between community-acquired and hospital-acquired bacterial infections: a cross-sectional comparative study.
  4. Clinical factors associated with multidrug-resistant bacterial infection among adult medical inpatients: a cross-sectional analytical study.
  5. Association between prior antibiotic exposure and multidrug-resistant bacterial infection: a cross-sectional analytical study.
  6. Association between recent hospitalisation and multidrug-resistant infection among adult medical patients: a cross-sectional analytical study.
  7. Association between diabetes mellitus and multidrug-resistant bacterial infection among hospitalised adults: a cross-sectional study.
  8. Comparison of antimicrobial resistance patterns in diabetic and non-diabetic adult medical patients: a cross-sectional comparative study.
  9. Prevalence of extended-spectrum beta-lactamase-producing Enterobacterales among clinical isolates from adult medical patients: a cross-sectional microbiological study.
  10. Clinical factors associated with extended-spectrum beta-lactamase-producing urinary tract infections: a cross-sectional analytical study.
  11. Prevalence of carbapenem-resistant Gram-negative organisms among adult medical inpatients: a cross-sectional microbiological study.
  12. Comparison of clinical characteristics of carbapenem-resistant and carbapenem-susceptible Gram-negative infections: a cross-sectional comparative study.
  13. Prevalence of methicillin-resistant Staphylococcus aureus among clinical isolates from adult medical patients: a cross-sectional study.
  14. Comparison of community-associated and hospital-associated methicillin-resistant Staphylococcus aureus infections: a cross-sectional comparative study.
  15. Prevalence of hospital-acquired infections among adult patients admitted to General Medicine wards: a point-prevalence cross-sectional study.
  16. Distribution of hospital-acquired infection sites among adult medical inpatients: a cross-sectional observational study.
  17. Prevalence and microbiological profile of hospital-acquired pneumonia among adult medical inpatients: a cross-sectional study.
  18. Comparison of antimicrobial resistance patterns in community-acquired and hospital-acquired pneumonia: a cross-sectional comparative study.
  19. Prevalence and microbiological profile of catheter-associated urinary tract infection among adult medical inpatients: a cross-sectional study.
  20. Association between urinary catheter use and multidrug-resistant urinary infection among hospitalised adults: a cross-sectional analytical study.
  21. Prevalence of bloodstream infection associated with intravascular catheters among adult medical inpatients: a cross-sectional observational study.
  22. Microbiological profile and antimicrobial resistance pattern of bloodstream infections among hospitalised adults: a cross-sectional study.
  23. Point prevalence of antibiotic use among adult patients admitted to General Medicine wards: a cross-sectional observational study.
  24. Pattern of empirical antibiotic prescribing among adult medical inpatients with suspected infection: a cross-sectional study.
  25. Comparison of empirical antibiotic therapy with microbiological susceptibility results among culture-positive infections: a cross-sectional comparative study.
  26. Proportion of inappropriate empirical antibiotic selection among adult medical inpatients based on culture susceptibility results: a cross-sectional analytical study.
  27. Pattern of broad-spectrum antibiotic use among adults admitted to General Medicine wards: a cross-sectional observational study.
  28. Association between recent broad-spectrum antibiotic exposure and colonization or infection with multidrug-resistant organisms: a cross-sectional analytical study.
  29. Knowledge and practices regarding antimicrobial use among adult patients attending a tertiary care hospital: a cross-sectional study.
  30. Prevalence of self-medication with antibiotics before hospital presentation among adults with acute infectious illness: a cross-sectional observational study.
  31. Association between over-the-counter antibiotic use and culture negativity among adults with suspected bacterial infection: a cross-sectional analytical study.
  32. Comparison of antimicrobial resistance patterns among common bacterial infections in community-dwelling and recently hospitalised adults: a cross-sectional comparative study.
  33. Clinical, microbiological, and treatment-related factors associated with multidrug-resistant infection among adults admitted to a tertiary care General Medicine department in India: a hospital-based analytical cross-sectional study.

Not the general medicine subspeciality you need? Infectious diseases is one section of our full general medicine collection — the hub page lists every subspeciality, each with its own free topic list. Updated September 2026.

Browse all General Medicine Thesis Topics →Browse Premium Infectious Disease Topics →

📌 Updated for 2026–2027 MD/DNB Medicine Infectious Diseases admissions

The page has been reviewed for practical feasibility, microbiological confirmation, realistic case definitions and investigations commonly available in medical colleges and teaching hospitals.

  • Most topics can be completed with complete blood counts, liver and renal function tests, inflammatory markers, urine and blood cultures, sputum testing, serology, cerebrospinal fluid analysis and routine imaging already obtained during clinical care.
  • Research-only molecular panels, metagenomic sequencing, specialised cytokine assays and expensive pathogen testing are not required for the majority of projects.
  • Strong publication potential lies in acute febrile illness, antimicrobial resistance, culture-positive and culture-negative sepsis, tuberculosis and diabetes, multidrug-resistant urinary infection, hospital-acquired infection and antibiotic stewardship.
Generate a protocol from any topic above

Select Generate Protocol → beside any title in the list above and receive a submission-ready document built around that topic, containing all eighteen components:

  • Introduction / Synopsis
  • Research Question
  • Aim of the Study
  • Primary Objective
  • Secondary Objectives
  • Materials and Methods
  • Inclusion Criteria
  • Exclusion Criteria
  • Sample Size Calculation
  • Methodology
  • Statistical Analysis
  • Ethical Considerations
  • Review of Literature
  • References
  • Gantt Chart / Study Timeline
  • Patient Information Sheet
  • Consent Form
  • Data Collection Form

Already have your thesis title?

Generate the full infectious diseases protocol directly — objectives, methodology, sample size, statistics, timeline, references and annexures.

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Alongside infectious diseases protocols and synopses, support is also available for departmental presentations, journal club presentations, ethics committee presentations, and posters and oral presentations for medical conferences — for postgraduate residents, board trainees and research scholars across India and the GCC. Prepared by a practising doctor with long experience in medical publishing and thesis supervision.

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Infectious diseases research outside India

The topics above work as research questions anywhere — what changes is the document the institution expects, and who approves it before data collection begins. The Gulf equivalent of an Indian synopsis is the infectious diseases research proposal submitted to an institutional review board, and it ordinarily carries three sections an Indian synopsis does not: a Gantt chart, a budget and resources section, and a Declaration of Helsinki statement.

Board and residency programmes — country by country

Saudi Arabia — SCFHS and the Saudi Board. Residency and fellowship training under the Saudi Commission for Health Specialties includes a research project with a set timeline, and the infectious diseases research proposal is the document prepared at the outset and cleared by the institutional review board before recruitment starts.

United Arab Emirates — DHA, DOH Abu Dhabi and MOHAP. Residents training in Dubai, Abu Dhabi and the northern emirates prepare an infectious diseases research protocol for their programme and submit it for institutional review board approval before any data are collected.

Qatar — DHP (formerly QCHP) and Hamad Medical Corporation. A infectious diseases IRB proposal is reviewed before recruitment, with the ethics section written to the institution's own template rather than a generic one.

Bahrain — NHRA. Trainees turning infectious diseases research topics into a project need the proposal cleared by their institutional research and ethics committee before fieldwork begins.

Oman — OMSB. Residency programmes under the Oman Medical Specialty Board include a research component, and the infectious diseases research proposal is the document assessed at the start of it.

Kuwait — KIMS. A infectious diseases study protocol goes to the institutional committee for approval before the project begins.

Arab Board programmes across the region. The Arab Board carries its own research requirement irrespective of the host country, and the infectious diseases proposal follows the same structure throughout.

Generate an infectious diseases research proposal →

Postgraduate degrees — Malaysia, the Gulf and beyond

Malaysia — MMed, the National Medical Research Register and MREC. A infectious diseases dissertation proposal for a Master of Medicine programme carried out in a Ministry of Health facility must be registered on the NMRR and approved by the Medical Research and Ethics Committee before the study begins, and the guidance asks for submission four to six months ahead of data collection. Every investigator on the study team registers on the NMRR as well, so the methodology, ethics and team sections are written in far more detail than an Indian synopsis requires.

PhD and Master's candidates elsewhere. University programmes generally require a full infectious diseases research proposal of roughly 6,000 to 10,000 words, with an extended literature review, a theoretical framework and a detailed methodology chapter.

PhD and MMed proposals are written individually by a medical doctor and revised until the supervisor accepts them. They are not produced by the automated protocol generator.

Enquire about an infectious diseases PhD or MMed proposal →

🔥 Trending research areas in Infectious Diseases for 2026–27

  • Antimicrobial resistance and stewardship: resistance patterns, prior antibiotic exposure, empirical therapy concordance and de-escalation are increasingly important because they connect microbiology directly with prescribing practice.
  • Culture-negative infection: prior antibiotics, low organism burden and imperfect sampling can produce clinically important infection without microbiological confirmation, making case-definition work especially relevant.
  • Host factors and infection severity: diabetes, chronic kidney disease, obesity, undernutrition, older age and immunosuppression offer practical ways to study why the same pathogen produces different clinical outcomes.
  • Low-cost severity markers: platelet count, neutrophil-to-lymphocyte ratio, red-cell distribution width, serum albumin and routine biochemical abnormalities remain attractive when studied as adjuncts rather than replacements for validated clinical assessment.

Protocol and synopsis guidance

What an Infectious Diseases protocol must contain

Define how infection is established. The protocol should distinguish microbiologically confirmed infection, probable infection and clinically diagnosed infection. Culture, antigen detection, nucleic-acid testing, microscopy, serology and imaging do not have the same diagnostic meaning, so the reference standard should be stated explicitly.

Fix the sampling time in relation to treatment. Blood culture, urine culture, sputum testing, inflammatory markers and parasite detection can change after antibiotics, fluids or other treatment. The protocol should record whether samples were obtained before or after antimicrobial therapy and define how prior treatment will be handled analytically.

Separate infection, colonisation and contamination. A positive culture does not automatically prove invasive disease. The protocol should define how likely contaminants, colonising organisms, asymptomatic bacteriuria and repeated isolates will be classified, particularly in hospital-acquired infection and antimicrobial-resistance studies.

Define the analytical unit. Patients, infection episodes, cultures and isolates are different units. Repeat isolates from the same patient should not be counted as independent observations unless the protocol prespecifies an episode-based or isolate-based analysis and handles clustering appropriately.

Infectious Diseases synopsis versus Infectious Diseases protocol

The synopsis is the concise academic registration document. It usually contains the title, rationale, objectives, study design, setting, eligibility criteria, principal variables, sample size, analysis plan and ethical safeguards required by the institution or university.

The protocol is the operational document. It should additionally define the infection case criteria, specimen type, specimen-collection timing, microbiological method, contamination rules, prior antibiotic exposure, antimicrobial-resistance definitions, severity classification, follow-up window and handling of repeat infections or isolates.

Infectious-disease research is particularly vulnerable to verification bias. If only severe or test-positive patients undergo the definitive microbiological or imaging investigation, apparent diagnostic performance may be distorted. The protocol should therefore state which participants receive the reference test and how clinically suspected but test-negative cases will be classified.

Sample size and statistical analysis

Base the sample size on the primary objective. Prevalence studies need an expected proportion and precision; comparative studies need an expected group difference; diagnostic studies require assumptions for sensitivity or specificity; and prospective outcome studies need an expected event rate such as severe disease, organ dysfunction or mortality.

Do not inflate the sample by counting repeat cultures from one patient as independent patients. If the study is isolate-based, state that clearly and define how duplicate isolates from the same infection episode will be removed or handled. If it is patient-based, use one prespecified isolate or infection episode per participant.

Match the analysis to the diagnostic structure. Culture positivity, multidrug resistance, severe infection and organ dysfunction are categorical outcomes, while inflammatory markers and biochemical values are continuous measures. Diagnostic studies should report sensitivity, specificity and confidence intervals against the stated reference standard.

Plan important confounders before recruitment. Age, diabetes, prior antibiotic exposure, recent hospitalisation, immunosuppression, renal function, infection source and baseline severity can affect both microbiological findings and clinical outcomes. Prespecifying clinically important variables is preferable to testing every available laboratory parameter.

Frequently Asked Questions – Infectious Diseases Thesis Topics (2026–27)

1. How do I choose a feasible infectious diseases thesis topic?

For the 2026–2027 academic year, a feasible topic should use a common infection or syndrome, a routinely available diagnostic pathway, one clearly defined primary outcome and a recruitment period that matches seasonal case flow. Before finalising the title, confirm case volume, microbiology access, expected culture positivity, availability of susceptibility testing and whether the chosen infection is frequent enough during the thesis period.

2. Which study designs are commonly accepted for an infectious diseases thesis?

Cross-sectional, comparative cross-sectional, case-control, prospective observational, retrospective record-based, diagnostic accuracy, microbiological surveillance and clinical-audit designs are all suitable when they match the objective. A design should not be labelled cross-sectional if the primary outcome depends on future clinical deterioration, treatment response, recurrence or mortality.

3. What should I settle with my guide before registering the topic?

Settle the infection case definition, primary outcome, microbiological reference standard, timing of specimen collection, prior antibiotic window, severity definition, antimicrobial-resistance criteria, handling of repeat isolates, important confounders and main statistical comparison. If the project depends on a particular culture, serology or molecular assay, confirm routine availability and turnaround time before registration.

4. Can I study an infection if microbiological confirmation is not available in every patient?

Yes, but the protocol should create transparent diagnostic categories rather than treating all suspected cases as equivalent. Microbiologically confirmed, probable and clinically diagnosed infection can be analysed separately where appropriate. The proportion without definitive testing, reasons for missing confirmation and effect of prior antimicrobial therapy should be reported because these factors can systematically differ between mild and severe disease.

5. What is the difference between an infectious diseases synopsis and a protocol?

The synopsis is the shorter academic registration document, while the protocol contains the detailed operating rules needed to conduct the study reproducibly. In infectious diseases, these rules should include diagnostic categories, specimen timing, microbiological methods, prior antibiotic exposure, contamination rules, severity definitions, resistance criteria and handling of repeated infection episodes or isolates.

6. What ethical issues should an infectious diseases thesis address?

Prospective studies require informed consent, and paediatric studies require guardian consent with age-appropriate assent from about seven years where applicable. Record-based work may seek an ethics-approved waiver of consent when risk is minimal and confidentiality is protected. Research should not add lumbar puncture, imaging, invasive sampling or venepuncture solely to create data unless scientifically justified and approved; when extra blood sampling is necessary, the protocol should state an appropriate blood-volume limit. Separate consent is required for identifiable photographs of rashes, wounds or skin lesions. Newly detected severe infection, antimicrobial resistance requiring treatment change, positive human immunodeficiency virus or viral-hepatitis screening where applicable, or other clinically important results should have a named counselling, confirmation and referral pathway.

7. How should infection, colonisation, contamination and culture-negative disease be distinguished?

The protocol should not equate every positive culture with disease or every negative culture with absence of infection. Likely contaminants should be defined using specimen type, organism, number of positive samples and clinical context. Colonisation should be separated from symptomatic infection, particularly for urine, respiratory and wound isolates. Prior antibiotics can reduce culture yield, so culture-negative patients who otherwise fulfil a prespecified clinical and laboratory case definition may need a separate category. Antimicrobial-resistance analyses should also remove duplicate isolates from the same episode unless repeated isolates are an explicit part of the research question.

8. Can these topics be adapted for PhD or Gulf board research requirements?

Yes, but the scope and document type should be redesigned rather than simply expanding an MD synopsis. A PhD proposal generally requires a broader conceptual framework, stronger originality and more extensive methodology. Gulf training pathways may require a board research project rather than an Indian-style dissertation; this includes programmes linked to SCFHS and the Saudi Board, the Arab Board of Health Specializations, and DHP, DHA, DOH and MOHAP-linked training programmes. The same clinical question can often be adapted, but approval pathways, sample size, supervision and reporting requirements should be checked against the relevant programme.

9. When should I register my infectious diseases thesis topic?

Registration should occur after confirming expected case volume, seasonal availability, microbiology support, specimen workflow, diagnostic definition and analysis plan, while leaving sufficient time for ethics approval and recruitment. Topics dependent on monsoon infections, uncommon pathogens, specialised cultures or resistance phenotyping need an especially careful feasibility check before formal submission.

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