Cardiology Thesis Topics For DM/dnb

Cardiology Thesis Topics

This collection of cardiology thesis topics for MD Medicine is intended for MD and DNB General Medicine residents studying coronary disease, heart failure, hypertension, arrhythmias, valvular disease and cardiovascular risk. These cardiology research topics for medicine residents can be shaped into projects completable within one thesis period using patients and investigations already available in medicine wards, outpatient clinics and collaborating cardiology units, after confirming recruitment and follow-up capacity. ECG, routine laboratory tests and standard echocardiography support many feasible questions, with advanced investigations selected only where access is established. Each chosen question should be developed into a cardiology protocol for MD Medicine and an institution-specific cardiology synopsis for medicine residents.

Last reviewed and updated: September 2026 · 2026–27 admissions

Our MD Medicine Thesis Guidance provides structured protocols, sample size formulas, and institutional review board (IRB) layout guides.

Acute Coronary Syndrome

  1. Predictive performance of the Global Registry of Acute Coronary Events risk score for in-hospital mortality and major cardiovascular complications in adults admitted with acute coronary syndrome: a prospective observational validation study.
  2. Clinical utility of the Thrombolysis in Myocardial Infarction risk score for predicting in-hospital recurrent ischaemia and mortality in adults with non-elevation acute coronary syndrome: a prospective observational study.
  3. Prognostic value of admission blood glucose for in-hospital heart failure, arrhythmia and mortality in adults presenting with acute myocardial infarction, irrespective of diabetes status: a prospective observational study.
  4. Relationship between glycated haemoglobin and angiographic coronary artery disease severity in adults with type 2 diabetes mellitus undergoing clinically indicated coronary angiography for acute coronary syndrome: a cross-sectional analytical study.
  5. Ability of admission shock index to identify adults with acute myocardial infarction who develop in-hospital hypotension, intensive care requirement or mortality: a prospective observational study.
  6. Spectrum of presentation delays and their determinants among adults with acute myocardial infarction, with comparison of in-hospital complications between early and delayed presenters: a prospective observational study.
  7. Comparative in-hospital outcomes of adults with acute myocardial infarction with and without previously diagnosed type 2 diabetes mellitus: a prospective comparative observational study assessing heart failure, arrhythmia and mortality.
  8. Diagnostic yield of glycated haemoglobin screening for previously unrecognized diabetes mellitus among adults admitted with first acute coronary syndrome: a cross-sectional study with in-hospital complication assessment.
  9. Prognostic significance of admission haemoglobin concentration for heart failure, transfusion requirement, length of stay and mortality in adults hospitalised with acute coronary syndrome: a prospective observational study.
  10. Utility of red cell distribution width for stratifying in-hospital mortality risk among adults admitted with acute coronary syndrome, using the Global Registry of Acute Coronary Events risk score for comparison: a prospective study.
  11. Comparison of in-hospital heart failure, arrhythmia and mortality between adults with acute coronary syndrome with and without chronic kidney disease defined by estimated glomerular filtration rate: a prospective observational study.
  12. Predictive value of admission serum sodium concentration for in-hospital heart failure, intensive care requirement and mortality among adults admitted with acute myocardial infarction: a prospective observational study.
  13. Clinical relevance of admission serum potassium abnormalities for documented arrhythmias during hospitalisation in adults with acute myocardial infarction: a prospective observational study using continuous clinical and electrocardiographic surveillance records.
  14. Performance of the Killip classification for predicting in-hospital mortality and length of stay among adults admitted with acute myocardial infarction: a prospective observational validation study.
  15. Incremental prognostic utility of neutrophil-to-lymphocyte ratio alongside the Global Registry of Acute Coronary Events risk score for in-hospital complications among adults with acute coronary syndrome: a prospective observational study.
  16. Comparative clinical profile and in-hospital outcomes of adults younger than forty-five years and older adults presenting with first acute myocardial infarction: a prospective observational study.
  17. Determinants of acute myocardial infarction before forty-five years of age among adults with first myocardial infarction compared with age-matched hospital controls without coronary artery disease: a case-control study.
  18. Echocardiographic left ventricular ejection fraction as a predictor of in-hospital heart failure, arrhythmia and mortality in adults admitted with acute myocardial infarction: a prospective observational study.
  19. Bedside lung ultrasonography for detection of pulmonary congestion compared with chest radiography in adults with acute coronary syndrome and suspected acute heart failure: a prospective diagnostic accuracy study.
  20. Frequency and short-term consequences of right ventricular systolic dysfunction identified by echocardiography among adults admitted with inferior wall acute myocardial infarction: a prospective observational study assessing in-hospital hypotension and mortality.
  21. Prognostic performance of admission heart rate for in-hospital heart failure and mortality in adults admitted with acute myocardial infarction: a prospective observational study with comparison across predefined heart-rate categories.
  22. Value of serum uric acid measured at admission for predicting in-hospital heart failure, length of stay and mortality among adults with acute coronary syndrome: a prospective observational study.
  23. Angiographic disease burden across categories of serum triglyceride to high-density lipoprotein cholesterol ratio in adults undergoing clinically indicated coronary angiography for acute coronary syndrome: a cross-sectional analytical study.
  24. Influence of active tobacco use on age at presentation, angiographic disease extent and in-hospital complications among adults with first acute myocardial infarction: a prospective observational study.
  25. Prevalence and clinical impact of previously unrecognized hypertension among adults admitted with first acute coronary syndrome, assessed against documented blood pressure history and in-hospital cardiovascular complications: a cross-sectional analytical study.
  26. Agreement between visual echocardiographic estimation and calculated left ventricular ejection fraction for classification of systolic dysfunction in adults hospitalised with acute myocardial infarction: a prospective method-agreement study.
  27. Predictive usefulness of admission respiratory rate for acute pulmonary oedema, ventilatory support requirement and in-hospital mortality among adults presenting with acute myocardial infarction: a prospective observational study.
  28. Comparative in-hospital outcomes of adults with acute coronary syndrome presenting during working hours and non-working hours, using mortality, reperfusion delay and length of stay as outcomes: a retrospective record-based study.
  29. Audit of guideline-recommended antiplatelet, lipid-lowering and secondary prevention therapy at discharge among adults hospitalised with acute coronary syndrome in a teaching hospital: a retrospective record-based study.
  30. Twelve-week adherence to prescribed secondary prevention medicines after acute myocardial infarction and its determinants among adults discharged from a tertiary care hospital: a prospective observational follow-up study.

Heart Failure

  1. Prognostic performance of admission serum sodium concentration for intensive care requirement, length of stay and in-hospital mortality among adults with acute decompensated heart failure: a prospective observational study.
  2. Utility of blood urea nitrogen measured at admission for predicting in-hospital mortality and prolonged hospitalisation among adults admitted with acute decompensated heart failure: a prospective observational study.
  3. Frequency of worsening renal function during hospitalisation and its relationship with in-hospital mortality among adults treated for acute decompensated heart failure: a prospective observational study.
  4. Predictive value of red cell distribution width for in-hospital mortality and prolonged length of stay among adults with acute decompensated heart failure: a prospective observational study.
  5. Clinical burden of anaemia among adults admitted with chronic heart failure exacerbation and its relationship with functional class, hospitalisation duration and in-hospital mortality: a prospective observational study.
  6. Prevalence of iron deficiency and comparison of six-minute walk distance between iron-deficient and iron-replete adults with stable chronic heart failure: a cross-sectional analytical study.
  7. Bedside lung ultrasonography compared with chest radiography for detection of pulmonary congestion among adults admitted with suspected acute decompensated heart failure: a prospective diagnostic accuracy study.
  8. Agreement between inferior vena cava collapsibility and bedside clinical congestion assessment among adults admitted with acute decompensated heart failure: a prospective method-comparison study.
  9. Inter-observer reproducibility of inferior vena cava diameter and collapsibility measurements performed by two trained physicians in adults with acute decompensated heart failure: a prospective observer-agreement study.
  10. Relationship of tricuspid annular plane systolic excursion with functional limitation and in-hospital mortality among adults with heart failure and echocardiographic right ventricular dysfunction: a prospective observational study.
  11. Predictive usefulness of admission systolic blood pressure for intensive care requirement and in-hospital mortality among adults presenting with acute decompensated heart failure: a prospective observational study.
  12. Clinical outcomes across admission heart-rate categories among adults hospitalised with acute decompensated heart failure, using in-hospital mortality and length of stay as endpoints: a prospective observational study.
  13. Value of serum uric acid for identifying adults with decompensated chronic heart failure at increased risk of prolonged hospitalisation and in-hospital mortality: a prospective observational study.
  14. Prognostic utility of serum albumin for in-hospital mortality and prolonged hospitalisation among adults presenting with acute decompensated heart failure and peripheral oedema: a prospective observational study.
  15. Comparative outcomes of adults with acute decompensated heart failure with and without type 2 diabetes mellitus, assessed by intensive care requirement, length of stay and in-hospital mortality: a prospective study.
  16. Burden of previously unrecognized thyroid dysfunction among adults with chronic heart failure and its relationship with functional class and clinically documented rhythm abnormalities: a cross-sectional analytical study.
  17. Effect of atrial fibrillation on length of stay and in-hospital mortality compared with sinus rhythm among adults admitted with acute decompensated heart failure: a prospective comparative observational study.
  18. Six-minute walk distance compared with New York Heart Association functional classification for assessment of functional limitation among adults with stable chronic heart failure: a cross-sectional analytical study.
  19. Echocardiographic mitral annular plane systolic excursion compared with left ventricular ejection fraction for classification of left ventricular systolic dysfunction in adults with chronic heart failure: a cross-sectional method-comparison study.
  20. Clinical significance of left atrial volume in adults with chronic heart failure, assessed against New York Heart Association functional class and six-minute walk distance: a cross-sectional analytical study.
  21. Prediction of non-invasive ventilation requirement using admission respiratory rate and oxygen saturation among adults admitted with acute decompensated heart failure: a prospective observational study.
  22. Frequency and determinants of medication non-adherence among adults admitted with worsening chronic heart failure, using a validated adherence questionnaire and precipitating cause of hospitalisation: a cross-sectional analytical study.
  23. Twelve-week symptom and functional outcomes among adults with heart failure and reduced left ventricular ejection fraction discharged on guideline-recommended medical therapy: a prospective observational follow-up study.
  24. Validation of the Clinical Frailty Scale for prediction of prolonged hospitalisation and in-hospital mortality among adults aged sixty years or older admitted with acute heart failure: a prospective observational study.
  25. Comparison of clinical congestion score at admission and discharge for predicting residual symptoms at twelve weeks among adults hospitalised with acute decompensated heart failure: a prospective observational study.
  26. Diagnostic accuracy of physical examination findings for pulmonary congestion compared with bedside lung ultrasonography among adults presenting with suspected acute decompensated heart failure: a prospective diagnostic study.
  27. Spectrum of precipitating factors for acute decompensated heart failure and their relationship with length of stay among adults admitted to a tertiary teaching hospital: a prospective observational study.
  28. Readiness of discharge assessed by clinical decongestion criteria and twelve-week symptom status among adults hospitalised with acute decompensated heart failure: a prospective observational follow-up study.
  29. Hospital audit of documented assessment of left ventricular function and guideline-recommended discharge medicines among adults admitted with heart failure: a retrospective record-based study using standard treatment recommendations as reference.
  30. Comparative clinical characteristics and in-hospital outcomes of adults with preserved and reduced left ventricular ejection fraction admitted with acute heart failure: a prospective observational study.

Hypertension and Target Organ Damage

  1. Prevalence of echocardiographic left ventricular hypertrophy among adults receiving treatment for primary hypertension and its relationship with blood pressure control during outpatient assessment: a cross-sectional analytical study.
  2. Diagnostic performance of electrocardiographic criteria for left ventricular hypertrophy compared with echocardiographic left ventricular mass assessment among adults with primary hypertension: a cross-sectional diagnostic accuracy study.
  3. Burden of albuminuria among adults with primary hypertension and comparison of urine albumin to creatinine ratio between controlled and uncontrolled blood pressure groups: a cross-sectional analytical study.
  4. Relationship between duration of hypertension and echocardiographic left ventricular structural changes among adults receiving antihypertensive treatment in a tertiary care outpatient clinic: a cross-sectional analytical study.
  5. Frequency of previously unrecognized chronic kidney disease among adults with hypertension, using estimated glomerular filtration rate and urine albumin to creatinine ratio as reference measures: a cross-sectional screening study.
  6. Clinical profile of resistant hypertension among adults taking three or more antihypertensive medicines and comparison with adults achieving blood pressure control on fewer medicines: a comparative cross-sectional study.
  7. Determinants of uncontrolled blood pressure among adults receiving antihypertensive therapy, assessed using medication adherence, body mass index, dietary salt practices and treatment characteristics: a cross-sectional analytical study.
  8. Agreement between automated office blood pressure and conventional auscultatory blood pressure measurements in adults attending a hypertension clinic: a prospective method-agreement study using standardized repeated measurements.
  9. Inter-observer agreement of manual blood pressure measurements performed by two trained observers in adults attending a medicine outpatient department: a prospective observer-agreement study.
  10. Prevalence of orthostatic hypotension and its relationship with antihypertensive medication burden among adults aged sixty years or older receiving treatment for hypertension: a cross-sectional analytical study.
  11. Comparative frequency of target organ damage among newly diagnosed and previously treated adults with primary hypertension, assessed by albuminuria, fundus abnormalities and echocardiographic left ventricular hypertrophy: a cross-sectional study.
  12. Yield of fundus examination for hypertensive retinopathy among adults with newly diagnosed hypertension and its relationship with blood pressure severity at presentation: a cross-sectional analytical study.
  13. Concordance between hypertensive retinopathy grade and urine albumin to creatinine ratio among adults with primary hypertension attending a tertiary care clinic: a cross-sectional analytical study.
  14. Clinical utility of pulse pressure for identifying echocardiographic left ventricular hypertrophy among adults aged fifty years or older with primary hypertension: a cross-sectional diagnostic study.
  15. Relationship of body mass index and waist circumference with blood pressure control among adults receiving treatment for primary hypertension: a cross-sectional analytical study.
  16. Prevalence of masked poor blood pressure control detected through standardized home blood pressure records among treated adults with apparently controlled clinic hypertension: a cross-sectional observational study.
  17. Comparison of renal target organ damage between adults with isolated systolic hypertension and combined systolic-diastolic hypertension, using albuminuria and estimated glomerular filtration rate: a cross-sectional analytical study.
  18. Frequency of electrolyte abnormalities among adults receiving multidrug antihypertensive therapy and their relationship with diuretic exposure at routine outpatient evaluation: a cross-sectional analytical study.
  19. Twelve-week blood pressure control and medication adherence among adults newly started on treatment for primary hypertension in a government teaching hospital: a prospective observational follow-up study.
  20. Predictors of failure to achieve blood pressure control at twelve weeks among adults with newly diagnosed primary hypertension receiving usual clinical care: a prospective observational study.
  21. Comparison of blood pressure control between adults using single-pill combination therapy and those receiving equivalent medicines as separate tablets under routine care: a cross-sectional comparative study.
  22. Burden of polypharmacy and potentially inappropriate antihypertensive prescribing among adults aged sixty-five years or older with hypertension: a cross-sectional study using established prescribing criteria as reference.
  23. Diagnostic yield of serum creatinine, urine albumin to creatinine ratio and fundus examination for detecting occult target organ damage in asymptomatic adults with newly diagnosed hypertension: a cross-sectional study.
  24. Clinical characteristics of hypertensive emergencies presenting to a medical emergency department and determinants of in-hospital complications among affected adults: a prospective observational study.
  25. Predictive value of admission mean arterial pressure for in-hospital neurological, cardiac and renal complications among adults presenting with hypertensive emergency: a prospective observational study.
  26. Spectrum of acute target organ injury among adults presenting with hypertensive emergency, defined by routine neurological, renal, cardiac and fundus assessments: a prospective observational study.
  27. Comparison of in-hospital outcomes between adults presenting with hypertensive emergency with and without pre-existing chronic kidney disease: a prospective comparative observational study.
  28. Frequency and determinants of treatment default among adults previously diagnosed with hypertension who present with severe uncontrolled blood pressure to a teaching hospital: a cross-sectional analytical study.
  29. Audit of documentation, cardiovascular risk assessment and target organ screening among adults newly diagnosed with hypertension in a medicine outpatient department: a retrospective record-based study against standard treatment guidelines.
  30. Agreement between estimated cardiovascular risk categories derived from routinely recorded clinical variables and presence of hypertension-related target organ damage among adults with primary hypertension: a cross-sectional analytical study.

Arrhythmias and Conduction Disorders

  1. Clinical spectrum and precipitating factors of newly detected atrial fibrillation among adults admitted to medical wards, with assessment of in-hospital heart failure, stroke and mortality: a prospective observational study.
  2. Validation of the Congestive heart failure, Hypertension, Age, Diabetes mellitus, Stroke, Vascular disease, Age and Sex Category score against documented thromboembolic risk factors in adults with non-valvular atrial fibrillation: a cross-sectional study.
  3. Bleeding risk profile measured using the Hypertension, Abnormal renal or liver function, Stroke, Bleeding history, Labile coagulation, Elderly and Drugs or alcohol score among adults receiving anticoagulation for atrial fibrillation: a cross-sectional study.
  4. Prevalence of previously unrecognized thyroid dysfunction among adults presenting with newly diagnosed atrial fibrillation and its relationship with ventricular rate at presentation: a cross-sectional analytical study.
  5. Comparison of clinical characteristics and in-hospital complications between adults with atrial fibrillation and rapid ventricular response and those with controlled ventricular response: a prospective observational study.
  6. Echocardiographic left atrial size as a marker of persistent versus paroxysmal atrial fibrillation among adults undergoing routine cardiac evaluation: a cross-sectional analytical study.
  7. Frequency of electrolyte abnormalities among adults admitted with clinically significant supraventricular or ventricular arrhythmias and their relationship with arrhythmia type during hospitalisation: a prospective observational study.
  8. Diagnostic yield of a standard twelve-lead electrocardiogram for identifying the cause of recurrent palpitations among adults evaluated in a medicine outpatient clinic: a cross-sectional observational study.
  9. Clinical profile of adults presenting with symptomatic bradyarrhythmia and predictors of temporary pacing requirement during hospitalisation: a prospective observational study.
  10. Spectrum of conduction abnormalities among adults admitted with acute myocardial infarction and their relationship with in-hospital mortality and length of stay: a prospective observational study.
  11. Predictive value of serum potassium at admission for clinically documented arrhythmias among adults hospitalised with acute decompensated heart failure: a prospective observational study.
  12. Comparison of arrhythmia burden during hospitalisation between adults with acute myocardial infarction with and without left ventricular systolic dysfunction: a prospective comparative observational study.
  13. Prevalence of atrial fibrillation among adults with rheumatic mitral stenosis and its relationship with left atrial diameter and functional class: a cross-sectional analytical study.
  14. Clinical determinants of inadequate ventricular rate control among adults receiving routine treatment for persistent atrial fibrillation: a cross-sectional analytical study using resting heart rate as the outcome.
  15. Agreement between pulse palpation and electrocardiographic rhythm diagnosis for detection of atrial fibrillation among adults aged sixty-five years or older attending a medicine outpatient department: a diagnostic accuracy study.
  16. Diagnostic accuracy of automated blood pressure device irregular-pulse notification for atrial fibrillation compared with twelve-lead electrocardiography among adults aged sixty-five years or older: a prospective diagnostic study.
  17. Frequency of asymptomatic atrial fibrillation detected through opportunistic pulse screening followed by electrocardiography among adults aged sixty-five years or older attending general medicine clinics: a cross-sectional screening study.
  18. Comparative clinical profile of adults with valvular and non-valvular atrial fibrillation, assessed by age, comorbidities, thromboembolic risk factors and in-hospital complications: a cross-sectional analytical study.
  19. Patterns of antithrombotic prescribing among adults with atrial fibrillation and concordance with documented stroke and bleeding risk assessment at hospital discharge: a retrospective record-based audit.
  20. Twelve-week adherence to prescribed anticoagulant therapy and determinants of non-adherence among adults with atrial fibrillation discharged from a tertiary care hospital: a prospective observational follow-up study.
  21. Frequency and causes of inadequate anticoagulation among adults receiving vitamin K antagonist therapy for valvular atrial fibrillation, assessed against contemporaneous coagulation measurements: a cross-sectional analytical study.
  22. Clinical utility of resting ventricular rate for predicting in-hospital heart failure among adults admitted with atrial fibrillation: a prospective observational study comparing predefined ventricular-rate categories.
  23. Prevalence of atrial fibrillation among adults admitted with ischaemic stroke and its relationship with stroke severity measured using the National Institutes of Health Stroke Scale: a cross-sectional analytical study.
  24. Relationship between left atrial enlargement and ischaemic stroke history among adults with non-valvular atrial fibrillation: a case-control study comparing patients with and without previous documented stroke.
  25. Predictors of in-hospital mortality among adults admitted with ventricular tachyarrhythmia, using underlying structural heart disease, serum electrolytes and haemodynamic status as candidate clinical variables: a prospective observational study.
  26. Spectrum of arrhythmias occurring during acute febrile illness among hospitalised adults and comparison of in-hospital outcomes between those with and without documented rhythm disturbances: a prospective observational study.
  27. Clinical characteristics of adults with complete heart block and factors associated with permanent pacemaker implantation during the index hospitalisation: a retrospective record-based study.
  28. Aetiological profile of newly diagnosed complete heart block among adults presenting to a tertiary hospital and its relationship with in-hospital haemodynamic complications: a prospective observational study.
  29. Audit of recommended anticoagulation assessment and prescription at discharge among adults with atrial fibrillation admitted under general medicine: a retrospective record-based study using guideline-defined eligibility as reference.
  30. Agreement between two clinicians interpreting routine twelve-lead electrocardiograms for atrial fibrillation, atrioventricular block and bundle branch conduction abnormalities in hospitalised adults: a prospective observer-agreement study.

Valvular and Rheumatic Heart Disease

  1. Clinical spectrum of rheumatic mitral stenosis among adults attending a tertiary care hospital and its relationship with echocardiographic valve area and New York Heart Association functional class: a cross-sectional analytical study.
  2. Prevalence of atrial fibrillation among adults with rheumatic mitral stenosis and comparison of left atrial dimensions between patients with atrial fibrillation and sinus rhythm: a cross-sectional study.
  3. Functional limitation measured by six-minute walk distance across echocardiographic severity categories of rheumatic mitral stenosis in adults receiving routine care: a cross-sectional analytical study.
  4. Diagnostic performance of physical examination findings for severe mitral stenosis compared with routine transthoracic echocardiography among adults with suspected rheumatic mitral valve disease: a prospective diagnostic accuracy study.
  5. Clinical utility of tricuspid regurgitation velocity for identifying functional limitation among adults with rheumatic mitral stenosis undergoing routine echocardiography: a cross-sectional analytical study.
  6. Frequency of pulmonary hypertension and its relationship with mitral valve area among adults with rheumatic mitral stenosis undergoing clinically indicated echocardiography: a cross-sectional analytical study.
  7. Comparison of functional status and right ventricular systolic function between adults with rheumatic mitral stenosis with and without echocardiographic pulmonary hypertension: a cross-sectional comparative study.
  8. Agreement between mitral valve area estimated by pressure half-time and planimetry in adults with rheumatic mitral stenosis undergoing routine transthoracic echocardiography: a prospective method-agreement study.
  9. Inter-observer agreement for echocardiographic grading of rheumatic mitral stenosis severity between two trained observers in adults undergoing routine cardiac evaluation: a prospective observer-agreement study.
  10. Clinical determinants of atrial fibrillation among adults with rheumatic mitral stenosis, assessed using age, left atrial diameter and echocardiographic valve severity: a cross-sectional analytical study.
  11. Prevalence of anaemia among adults with rheumatic valvular heart disease and its relationship with functional class and six-minute walk distance: a cross-sectional analytical study.
  12. Spectrum of multivalvular involvement among adults with established rheumatic heart disease and its relationship with New York Heart Association functional class: a cross-sectional observational study.
  13. Echocardiographic predictors of right ventricular dysfunction among adults with rheumatic mitral stenosis and pulmonary hypertension: a cross-sectional analytical study using tricuspid annular plane systolic excursion as outcome.
  14. Clinical profile and in-hospital outcomes of adults admitted with acute decompensated heart failure due to rheumatic valvular disease: a prospective observational study assessing mortality and length of stay.
  15. Predictive value of admission serum sodium for in-hospital mortality among adults admitted with decompensated heart failure secondary to rheumatic valvular heart disease: a prospective observational study.
  16. Burden of previously unrecognized rheumatic valvular disease among adults presenting with newly diagnosed atrial fibrillation, using transthoracic echocardiography as the reference evaluation: a cross-sectional screening study.
  17. Comparison of functional limitation between adults with isolated mitral stenosis and mixed mitral stenosis with regurgitation using six-minute walk distance and functional class: a cross-sectional study.
  18. Frequency of left atrial enlargement among adults with rheumatic mitral regurgitation and its relationship with atrial fibrillation detected on electrocardiography: a cross-sectional analytical study.
  19. Clinical and echocardiographic profile of adults with chronic severe mitral regurgitation and preserved left ventricular ejection fraction: a cross-sectional study assessing symptoms and chamber dimensions.
  20. Diagnostic value of bedside clinical signs for severe aortic stenosis compared with routine transthoracic echocardiographic severity assessment among symptomatic adults: a prospective diagnostic accuracy study.
  21. Functional status across echocardiographic severity categories of aortic stenosis among adults undergoing routine evaluation, measured using New York Heart Association functional class and six-minute walk distance: a cross-sectional study.
  22. Prevalence of left ventricular hypertrophy and its relationship with echocardiographic aortic stenosis severity among adults with calcific aortic valve disease: a cross-sectional analytical study.
  23. Comparison of clinical presentation and echocardiographic characteristics between rheumatic and degenerative valvular heart disease among adults attending a tertiary care hospital: a cross-sectional comparative study.
  24. Spectrum of anticoagulation control among adults with mechanical prosthetic heart valves receiving vitamin K antagonist therapy and determinants of measurements outside the prescribed therapeutic range: a cross-sectional analytical study.
  25. Frequency of bleeding and thromboembolic complications during the preceding six months among adults with mechanical prosthetic valves receiving anticoagulation, compared across documented anticoagulation-control categories: a cross-sectional study.
  26. Twelve-week adherence to secondary prophylaxis among adults with rheumatic heart disease prescribed regular benzathine benzylpenicillin under routine care: a prospective observational study assessing missed doses and determinants.
  27. Audit of secondary rheumatic fever prophylaxis documentation and adherence among adults with established rheumatic heart disease attending a teaching hospital: a retrospective record-based study against standard treatment recommendations.
  28. Clinical determinants of poor functional status among adults with chronic valvular heart disease, assessed using valve severity, rhythm, anaemia and pulmonary hypertension: a cross-sectional analytical study.
  29. Agreement between bedside functional class and six-minute walk distance for grading exercise limitation among adults with moderate-to-severe valvular heart disease: a cross-sectional method-comparison study.
  30. Hospital audit of echocardiographic assessment, anticoagulation evaluation and discharge therapy among adults admitted with rheumatic valvular heart disease: a retrospective record-based study using standard care recommendations as reference.

Cardiomyopathies

  1. Clinical and echocardiographic profile of adults with newly diagnosed nonischemic dilated cardiomyopathy and its relationship with New York Heart Association functional class at presentation: a cross-sectional observational study.
  2. Prevalence of previously unrecognized thyroid dysfunction among adults with nonischemic dilated cardiomyopathy and its relationship with left ventricular ejection fraction and resting heart rate: a cross-sectional analytical study.
  3. Burden of anaemia in adults with dilated cardiomyopathy and comparison of six-minute walk distance between patients with and without anaemia: a cross-sectional analytical study.
  4. Predictive value of admission serum sodium for in-hospital mortality and prolonged hospitalisation among adults admitted with decompensated heart failure due to dilated cardiomyopathy: a prospective observational study.
  5. Utility of red cell distribution width for stratifying in-hospital mortality risk among adults with decompensated dilated cardiomyopathy: a prospective observational study using left ventricular ejection fraction for clinical comparison.
  6. Echocardiographic right ventricular systolic function as a predictor of in-hospital mortality among adults admitted with decompensated dilated cardiomyopathy: a prospective observational study using tricuspid annular plane systolic excursion.
  7. Functional limitation across categories of left ventricular ejection fraction among adults with nonischemic dilated cardiomyopathy, assessed by six-minute walk distance: a cross-sectional analytical study.
  8. Relationship between left atrial volume and functional class among adults with dilated cardiomyopathy receiving routine outpatient care: a cross-sectional analytical study using transthoracic echocardiography.
  9. Frequency of atrial fibrillation and ventricular arrhythmias among adults with dilated cardiomyopathy and comparison of functional status between patients with and without documented arrhythmia: a cross-sectional study.
  10. Determinants of prolonged hospitalisation among adults admitted with acute decompensation of dilated cardiomyopathy, assessed using renal function, serum sodium, blood pressure and ventricular function: a prospective observational study.
  11. Comparison of clinical characteristics and in-hospital outcomes between adults with ischaemic and nonischemic dilated cardiomyopathy admitted with acute heart failure: a prospective comparative observational study.
  12. Prevalence of type 2 diabetes mellitus among adults with dilated cardiomyopathy and its relationship with functional status and left ventricular systolic function: a cross-sectional analytical study.
  13. Clinical utility of inferior vena cava collapsibility for assessment of systemic congestion among adults with decompensated dilated cardiomyopathy, compared with a standardized bedside congestion score: a cross-sectional diagnostic study.
  14. Agreement between mitral annular plane systolic excursion and left ventricular ejection fraction for classification of systolic dysfunction among adults with dilated cardiomyopathy: a cross-sectional method-comparison study.
  15. Prognostic value of admission systolic blood pressure for in-hospital mortality among adults presenting with decompensated dilated cardiomyopathy: a prospective observational study comparing predefined blood-pressure categories.
  16. Frequency of chronic kidney disease among adults with dilated cardiomyopathy and its relationship with functional limitation measured by six-minute walk distance: a cross-sectional analytical study.
  17. Burden of iron deficiency among adults with stable dilated cardiomyopathy and its relationship with functional class and six-minute walk distance: a cross-sectional analytical study.
  18. Clinical and echocardiographic characteristics of adults with hypertrophic cardiomyopathy attending a tertiary hospital, with comparison of symptomatic and asymptomatic patients: a cross-sectional observational study.
  19. Prevalence of atrial fibrillation among adults with hypertrophic cardiomyopathy and its relationship with left atrial enlargement and symptom burden: a cross-sectional analytical study.
  20. Relationship between maximum ventricular wall thickness and functional limitation among adults with hypertrophic cardiomyopathy undergoing routine echocardiographic evaluation: a cross-sectional analytical study.
  21. Diagnostic yield of family history and electrocardiography for identifying first-degree relatives requiring echocardiographic evaluation among families of adults with hypertrophic cardiomyopathy: a cross-sectional screening study.
  22. Clinical profile of adults with peripartum cardiomyopathy presenting during late pregnancy or within five months after delivery and predictors of left ventricular recovery at three months: a prospective observational study.
  23. Three-month change in left ventricular ejection fraction among women with peripartum cardiomyopathy receiving usual care and clinical factors associated with recovery: a prospective observational follow-up study.
  24. Frequency of ventricular thrombus identified on routine echocardiography among adults with severe dilated cardiomyopathy and its relationship with left ventricular ejection fraction: a cross-sectional analytical study.
  25. Spectrum of precipitating factors for acute decompensation among adults with established dilated cardiomyopathy and their relationship with in-hospital length of stay: a prospective observational study.
  26. Twelve-week medication adherence among adults with dilated cardiomyopathy discharged after acute heart failure hospitalisation and determinants of non-adherence: a prospective observational follow-up study.
  27. Comparative functional status of adults with dilated cardiomyopathy with and without secondary mitral regurgitation, assessed using six-minute walk distance and functional class: a cross-sectional analytical study.
  28. Prognostic performance of the Clinical Frailty Scale for in-hospital outcomes among adults aged sixty years or older admitted with cardiomyopathy-related heart failure: a prospective observational validation study.
  29. Audit of aetiological evaluation and guideline-recommended medical therapy among adults with newly diagnosed dilated cardiomyopathy in a teaching hospital: a retrospective record-based study against standard care recommendations.
  30. Agreement between two echocardiography observers for left ventricular ejection fraction classification in adults with dilated cardiomyopathy undergoing routine transthoracic echocardiography: a prospective observer-agreement study.

Pulmonary Hypertension and Right Heart Disease

  1. Clinical and echocardiographic profile of adults with pulmonary hypertension detected on routine transthoracic echocardiography and its relationship with New York Heart Association functional class: a cross-sectional observational study.
  2. Prevalence of pulmonary hypertension among adults with chronic obstructive pulmonary disease undergoing clinically indicated echocardiography and its relationship with spirometric airflow limitation severity: a cross-sectional analytical study.
  3. Functional limitation across echocardiographic pulmonary hypertension severity categories among adults with chronic obstructive pulmonary disease, measured using six-minute walk distance: a cross-sectional analytical study.
  4. Relationship between tricuspid annular plane systolic excursion and six-minute walk distance among adults with echocardiographic pulmonary hypertension: a cross-sectional analytical study.
  5. Clinical utility of right ventricular fractional area change for identifying functional impairment among adults with pulmonary hypertension undergoing routine echocardiography: a cross-sectional analytical study.
  6. Agreement between tricuspid annular plane systolic excursion and right ventricular fractional area change for classification of right ventricular systolic dysfunction in adults with pulmonary hypertension: a method-comparison study.
  7. Inter-observer agreement for tricuspid annular plane systolic excursion measurement among adults with pulmonary hypertension examined by two trained echocardiography observers: a prospective observer-agreement study.
  8. Frequency of right ventricular systolic dysfunction among adults with rheumatic mitral stenosis and pulmonary hypertension and its relationship with functional class: a cross-sectional analytical study.
  9. Clinical profile and in-hospital outcomes of adults admitted with decompensated right heart failure due to pulmonary hypertension: a prospective observational study assessing mortality and length of stay.
  10. Predictive value of admission serum sodium for in-hospital mortality and prolonged hospitalisation among adults admitted with pulmonary hypertension complicated by right heart failure: a prospective observational study.
  11. Utility of serum uric acid for identifying severe functional limitation among adults with pulmonary hypertension, using six-minute walk distance as the reference functional measure: a cross-sectional diagnostic study.
  12. Comparative right ventricular function in adults with pulmonary hypertension secondary to chronic lung disease and rheumatic mitral valve disease: a cross-sectional echocardiographic study.
  13. Prevalence of chronic hypoxaemia among adults with chronic obstructive pulmonary disease and comparison of pulmonary hypertension frequency between hypoxaemic and non-hypoxaemic groups: a cross-sectional analytical study.
  14. Diagnostic accuracy of clinical signs of right heart failure compared with echocardiographic right ventricular dysfunction among adults with suspected pulmonary hypertension: a prospective diagnostic accuracy study.
  15. Relationship between inferior vena cava diameter and systemic venous congestion score among adults with pulmonary hypertension and right heart failure: a cross-sectional analytical study using bedside ultrasonography.
  16. Frequency of electrocardiographic right-heart strain patterns among adults with echocardiographic pulmonary hypertension and their relationship with right ventricular systolic dysfunction: a cross-sectional analytical study.
  17. Clinical determinants of severe exercise limitation among adults with pulmonary hypertension, assessed using six-minute walk distance, haemoglobin concentration, oxygen saturation and right ventricular function: a cross-sectional analytical study.
  18. Comparison of six-minute walk distance between adults with pulmonary hypertension with preserved and impaired right ventricular systolic function on echocardiography: a cross-sectional comparative study.
  19. Burden of anaemia among adults with pulmonary hypertension and its relationship with functional class and six-minute walk distance: a cross-sectional analytical study.
  20. Frequency of chronic kidney disease among adults with pulmonary hypertension complicated by right heart failure and its relationship with hospitalisation duration: a prospective observational study.
  21. Spectrum of underlying diseases among adults newly identified with pulmonary hypertension on routine echocardiography in a tertiary care hospital: a cross-sectional observational study.
  22. Diagnostic yield of transthoracic echocardiography for pulmonary hypertension among adults with unexplained exertional dyspnoea after routine clinical and chest radiographic evaluation: a cross-sectional screening study.
  23. Clinical utility of resting oxygen saturation for identifying adults with chronic lung disease who have echocardiographic pulmonary hypertension: a cross-sectional diagnostic study.
  24. Prognostic significance of right ventricular systolic dysfunction for in-hospital mortality among adults admitted with acute pulmonary embolism diagnosed during routine clinical care: a prospective observational study.
  25. Clinical severity and in-hospital outcomes across echocardiographic right ventricular function categories among adults with acute pulmonary embolism: a prospective observational study.
  26. Comparison of heart rate, blood pressure and oxygen saturation between adults with acute pulmonary embolism with and without echocardiographic right ventricular dysfunction: a cross-sectional comparative study.
  27. Predictive performance of a simplified pulmonary embolism severity score for in-hospital mortality among adults with confirmed acute pulmonary embolism: a prospective observational validation study.
  28. Diagnostic yield of bedside echocardiographic right-heart findings among haemodynamically unstable adults with clinically confirmed acute pulmonary embolism: a prospective observational study using routine computed tomography findings as reference where available.
  29. Twelve-week functional status after hospitalisation for pulmonary hypertension-related right heart failure and its relationship with discharge right ventricular function: a prospective observational follow-up study.
  30. Hospital audit of aetiological evaluation and documented right ventricular assessment among adults diagnosed with pulmonary hypertension in a tertiary teaching hospital: a retrospective record-based study against recommended evaluation standards.

Cardiovascular Disease in Diabetes and Metabolic Disorders

  1. Prevalence of asymptomatic electrocardiographic abnormalities among adults with type 2 diabetes mellitus without known cardiovascular disease and their relationship with duration of diabetes and glycated haemoglobin: a cross-sectional study.
  2. Diagnostic yield of resting electrocardiography for previously unrecognized ischaemic changes among adults with type 2 diabetes mellitus and multiple cardiovascular risk factors: a cross-sectional screening study.
  3. Burden of echocardiographic left ventricular diastolic dysfunction among asymptomatic adults with type 2 diabetes mellitus and preserved left ventricular ejection fraction: a cross-sectional analytical study.
  4. Relationship between glycaemic control measured by glycated haemoglobin and left ventricular diastolic dysfunction among adults with type 2 diabetes mellitus without established coronary artery disease: a cross-sectional analytical study.
  5. Frequency of albuminuria and echocardiographic left ventricular hypertrophy among adults with type 2 diabetes mellitus and hypertension, with assessment of concordant target organ damage: a cross-sectional analytical study.
  6. Comparative cardiovascular risk-factor burden among adults with newly diagnosed and previously known type 2 diabetes mellitus attending a medicine outpatient clinic: a cross-sectional study assessing hypertension, dyslipidaemia, obesity and albuminuria.
  7. Prevalence of metabolic syndrome among adults with type 2 diabetes mellitus and comparison of electrocardiographic abnormalities between those with and without metabolic syndrome: a cross-sectional analytical study.
  8. Relationship between waist circumference and echocardiographic left ventricular mass among adults with type 2 diabetes mellitus and hypertension: a cross-sectional analytical study.
  9. Clinical utility of triglyceride to high-density lipoprotein cholesterol ratio for identifying metabolic syndrome among adults with type 2 diabetes mellitus: a cross-sectional diagnostic study using accepted metabolic syndrome criteria as reference.
  10. Comparison of cardiovascular risk-factor control between adults with type 2 diabetes mellitus attending regular follow-up and those with irregular follow-up: a cross-sectional analytical study.
  11. Prevalence of previously unrecognized hypertension among adults with type 2 diabetes mellitus attending a tertiary hospital and its relationship with albuminuria: a cross-sectional screening study.
  12. Diagnostic yield of urine albumin to creatinine ratio for occult renal cardiovascular risk among adults with type 2 diabetes mellitus who have preserved estimated glomerular filtration rate: a cross-sectional study.
  13. Relationship between diabetic retinopathy severity and albuminuria among adults with type 2 diabetes mellitus undergoing routine fundus and renal evaluation: a cross-sectional analytical study.
  14. Cardiovascular risk profile across glycated haemoglobin categories among adults with type 2 diabetes mellitus, assessed using blood pressure, lipid profile, albuminuria and obesity measures: a cross-sectional analytical study.
  15. Comparative in-hospital outcomes of acute myocardial infarction among adults with diabetes mellitus, newly detected diabetes mellitus and normal glycaemic status: a prospective comparative observational study.
  16. Predictive value of admission hyperglycaemia for in-hospital mortality among adults with acute myocardial infarction without previously diagnosed diabetes mellitus: a prospective observational study.
  17. Clinical impact of chronic kidney disease on in-hospital heart failure and mortality among adults with type 2 diabetes mellitus admitted with acute coronary syndrome: a prospective observational study.
  18. Prevalence of heart failure with preserved left ventricular ejection fraction among symptomatic adults with type 2 diabetes mellitus undergoing clinically indicated echocardiography: a cross-sectional observational study.
  19. Functional limitation in adults with type 2 diabetes mellitus and heart failure compared with adults with heart failure without diabetes, measured using six-minute walk distance: a comparative cross-sectional study.
  20. Burden of obesity among adults with hypertension and comparison of echocardiographic left ventricular hypertrophy prevalence across body mass index categories: a cross-sectional analytical study.
  21. Relationship between waist-to-height ratio and blood pressure control among overweight or obese adults receiving antihypertensive treatment: a cross-sectional analytical study.
  22. Diagnostic performance of body mass index compared with waist circumference for identifying metabolic syndrome among adults attending a general medicine outpatient clinic: a cross-sectional diagnostic study.
  23. Frequency of dyslipidaemia among adults with newly diagnosed type 2 diabetes mellitus and its relationship with glycated haemoglobin at initial assessment: a cross-sectional analytical study.
  24. Comparison of lipid profiles between adults with type 2 diabetes mellitus with and without albuminuria, using routine fasting lipid measurements and urine albumin to creatinine ratio: a cross-sectional study.
  25. Prevalence of subclinical hypothyroidism among adults with dyslipidaemia and comparison of lipid parameters between euthyroid and subclinically hypothyroid groups: a cross-sectional analytical study.
  26. Relationship between thyroid-stimulating hormone concentration and lipid profile among adults with newly diagnosed primary hypothyroidism without lipid-lowering therapy: a cross-sectional analytical study.
  27. Twelve-week change in blood pressure, glycated haemoglobin and lipid control among adults with diabetes mellitus and hypertension receiving routine integrated outpatient care: a prospective observational follow-up study.
  28. Medication adherence and attainment of blood pressure and glycaemic targets at twelve weeks among adults with coexisting type 2 diabetes mellitus and hypertension: a prospective observational study.
  29. Audit of cardiovascular risk-factor assessment and lipid-lowering therapy among adults with type 2 diabetes mellitus attending a teaching hospital: a retrospective record-based study against standard treatment recommendations.
  30. Concordance between routinely documented cardiovascular risk classification and actual burden of hypertension, dyslipidaemia, smoking, obesity and albuminuria among adults with type 2 diabetes mellitus: a cross-sectional analytical study.

Preventive Cardiology and Dyslipidaemia

  1. Prevalence and pattern of dyslipidaemia among adults attending a general medicine outpatient department and its relationship with age, sex, obesity and diabetes mellitus: a cross-sectional analytical study.
  2. Diagnostic utility of triglyceride to high-density lipoprotein cholesterol ratio for identifying metabolic syndrome among adults without established cardiovascular disease: a cross-sectional diagnostic study using accepted metabolic syndrome criteria as reference.
  3. Comparative lipid profiles of adults with and without central obesity attending a tertiary care hospital, using waist circumference as the defining anthropometric criterion: a cross-sectional analytical study.
  4. Relationship between body mass index and fasting lipid abnormalities among adults without previously diagnosed cardiovascular disease: a cross-sectional analytical study using routinely measured anthropometric and biochemical parameters.
  5. Burden of multiple cardiovascular risk factors among asymptomatic adults aged forty years or older attending a medicine outpatient department: a cross-sectional study assessing hypertension, diabetes mellitus, dyslipidaemia, smoking and obesity.
  6. Frequency of previously undiagnosed diabetes mellitus and hypertension among adults undergoing cardiovascular risk-factor screening in a teaching hospital: a cross-sectional screening study using standard diagnostic criteria.
  7. Clinical characteristics of adults with severe hypertriglyceridaemia identified during routine care and determinants of coexisting diabetes mellitus, obesity and fatty liver: a cross-sectional analytical study.
  8. Prevalence of low high-density lipoprotein cholesterol among adults attending a general medicine clinic and its relationship with smoking, obesity, diabetes mellitus and physical inactivity: a cross-sectional analytical study.
  9. Comparison of lipid abnormalities between current smokers and never-smokers without known cardiovascular disease: a cross-sectional analytical study using fasting lipid profile as the outcome measure.
  10. Relationship between smoking burden measured in pack-years and age at first acute myocardial infarction among adult current and former smokers: a cross-sectional analytical study.
  11. Determinants of continued tobacco use after acute myocardial infarction among adults attending twelve-week follow-up: a prospective observational study assessing dependence, counselling exposure and cessation status.
  12. Twelve-week adherence to lipid-lowering therapy among adults discharged after acute coronary syndrome and factors associated with missed medication: a prospective observational follow-up study.
  13. Proportion of adults achieving guideline-recommended low-density lipoprotein cholesterol goals twelve weeks after acute coronary syndrome under routine care: a prospective observational study.
  14. Comparison of twelve-week low-density lipoprotein cholesterol reduction between adults prescribed high-intensity and moderate-intensity statin therapy under routine clinical care after acute coronary syndrome: a prospective observational study.
  15. Frequency of documented statin intolerance among adults receiving lipid-lowering therapy and its relationship with treatment discontinuation during twelve-week follow-up: a prospective observational study.
  16. Audit of lipid profile testing and lipid-lowering therapy among adults admitted with acute coronary syndrome: a retrospective record-based study using contemporary secondary prevention recommendations as reference.
  17. Prevalence of metabolic syndrome among adults with premature coronary artery disease presenting before forty-five years of age: a cross-sectional analytical study using accepted metabolic syndrome criteria.
  18. Comparison of conventional cardiovascular risk factors between adults with premature acute myocardial infarction and age-matched hospital controls without clinically established coronary artery disease: a case-control study.
  19. Frequency of family history of premature coronary artery disease among adults presenting with acute myocardial infarction before forty-five years of age and its relationship with risk-factor clustering: a cross-sectional study.
  20. Clinical profile of women presenting with first acute coronary syndrome and comparison of cardiovascular risk-factor burden with age-matched men: a prospective comparative observational study.
  21. Burden of cardiovascular risk factors among postmenopausal women without established cardiovascular disease attending a medicine outpatient department: a cross-sectional observational study.
  22. Relationship between sedentary behaviour measured by a validated questionnaire and metabolic syndrome among adults attending a general medicine clinic: a cross-sectional analytical study using accepted metabolic syndrome criteria.
  23. Comparison of cardiovascular risk-factor burden between urban and rural adults attending the same tertiary care hospital: a cross-sectional analytical study assessing hypertension, diabetes mellitus, smoking, obesity and dyslipidaemia.
  24. Diagnostic yield of opportunistic blood pressure, glucose and lipid screening among attendants of hospitalised patients aged forty years or older without known cardiovascular disease: a cross-sectional screening study.
  25. Twelve-week lifestyle adherence after acute myocardial infarction and its relationship with smoking cessation, physical activity and dietary practices among adults receiving routine secondary prevention counselling: a prospective observational study.
  26. Determinants of poor adherence to cardiovascular preventive medicines among adults with established coronary artery disease attending outpatient follow-up: a cross-sectional analytical study using a validated medication adherence questionnaire.
  27. Comparison of medication adherence between adults prescribed once-daily and multiple-daily cardiovascular medicine regimens after acute coronary syndrome: a cross-sectional comparative study.
  28. Prevalence of polypharmacy among adults aged sixty-five years or older with cardiovascular disease and its relationship with medication non-adherence: a cross-sectional analytical study.
  29. Frequency of potentially inappropriate cardiovascular medication use among adults aged sixty-five years or older, assessed against established geriatric prescribing criteria: a cross-sectional observational study.
  30. Hospital audit of smoking-cessation advice, blood pressure assessment, diabetes screening and lipid-lowering therapy at discharge after acute coronary syndrome: a retrospective record-based study against secondary prevention standards.

Pericardial and Miscellaneous Cardiovascular Disorders

  1. Clinical spectrum and aetiological profile of adults presenting with pericardial effusion detected on routine echocardiography in a tertiary care hospital: a cross-sectional observational study using available clinical investigations.
  2. Prevalence of tuberculosis among adults with clinically significant pericardial effusion and its relationship with effusion size and presenting symptoms: a cross-sectional analytical study using routine diagnostic criteria.
  3. Diagnostic yield of clinical examination and chest radiography for moderate-to-large pericardial effusion compared with transthoracic echocardiography among symptomatic adults: a prospective diagnostic accuracy study.
  4. Clinical predictors of echocardiographic cardiac tamponade physiology among adults with moderate-to-large pericardial effusion undergoing routine evaluation: a prospective observational study.
  5. Comparison of clinical presentation between adults with tuberculous and non-tuberculous pericardial effusion diagnosed during routine care: a cross-sectional comparative study assessing symptoms, laboratory findings and echocardiographic features.
  6. Relationship between pericardial effusion size and haemodynamic findings among adults undergoing clinically indicated transthoracic echocardiography: a cross-sectional analytical study using blood pressure, heart rate and pulsus paradoxus.
  7. Agreement between clinical estimation and echocardiographic grading of pericardial effusion severity among adults with suspected pericardial disease: a prospective method-comparison study.
  8. Frequency of hypothyroidism among adults with newly detected pericardial effusion and comparison of effusion severity between hypothyroid and euthyroid patients: a cross-sectional analytical study.
  9. Clinical and echocardiographic profile of adults with pericardial effusion associated with chronic kidney disease and its relationship with renal dysfunction severity: a cross-sectional analytical study.
  10. Short-term change in pericardial effusion size over twelve weeks among adults receiving usual treatment for an established underlying cause: a prospective observational follow-up study using clinically scheduled echocardiography.
  11. Spectrum of cardiovascular manifestations among adults hospitalised with severe anaemia and comparison of heart failure frequency across haemoglobin severity categories: a prospective observational study.
  12. Frequency of high-output heart failure among adults with severe anaemia and its relationship with haemoglobin concentration and heart rate at admission: a cross-sectional analytical study.
  13. Clinical profile of adults admitted with acute heart failure precipitated by severe anaemia and predictors of prolonged hospitalisation: a prospective observational study.
  14. Prevalence of electrocardiographic and echocardiographic abnormalities among adults with overt primary hypothyroidism undergoing routine cardiovascular evaluation: a cross-sectional observational study.
  15. Comparison of heart rate, blood pressure and pericardial effusion frequency between adults with overt hypothyroidism and euthyroid controls: a comparative cross-sectional study.
  16. Cardiovascular manifestations of overt hyperthyroidism among adults presenting to a tertiary care hospital, with assessment of atrial fibrillation, heart failure and blood pressure abnormalities: a cross-sectional observational study.
  17. Predictors of atrial fibrillation among adults with overt hyperthyroidism, assessed using age, thyroid hormone levels, blood pressure and echocardiographic left atrial size: a cross-sectional analytical study.
  18. Clinical profile and in-hospital cardiovascular complications among adults admitted with organophosphorus poisoning, assessed by heart rate, blood pressure, electrocardiography and serum electrolytes: a prospective observational study.
  19. Frequency of cardiac rhythm abnormalities among adults hospitalised after acute organophosphorus poisoning and their relationship with poisoning severity and in-hospital mortality: a prospective observational study.
  20. Cardiovascular manifestations among adults admitted with snakebite and comparison of complications between patients with and without systemic envenomation: a prospective observational study assessing hypotension, arrhythmia and myocardial injury.
  21. Clinical utility of admission electrocardiography for identifying adults at risk of cardiovascular complications after snakebite with systemic envenomation: a prospective observational study using in-hospital complications as outcomes.
  22. Frequency of myocardial injury detected during routine care among adults hospitalised with sepsis and its relationship with in-hospital mortality and vasopressor requirement: a prospective observational study.
  23. Echocardiographic left ventricular systolic dysfunction among adults with sepsis undergoing clinically indicated echocardiography and its relationship with intensive care requirement and in-hospital mortality: a prospective observational study.
  24. Predictive value of admission lactate for cardiovascular organ dysfunction and in-hospital mortality among adults with sepsis: a prospective observational study using the sequential organ failure assessment score for comparison.
  25. Cardiovascular profile of adults with chronic kidney disease receiving maintenance haemodialysis, assessed by blood pressure, electrocardiography and routine transthoracic echocardiography: a cross-sectional observational study.
  26. Prevalence of left ventricular hypertrophy among adults receiving maintenance haemodialysis and its relationship with blood pressure control and anaemia: a cross-sectional analytical study.
  27. Frequency of intradialytic hypotension during routinely scheduled haemodialysis sessions and its relationship with pre-dialysis blood pressure and antihypertensive medication burden: a prospective observational study.
  28. Agreement between clinical volume-status assessment and inferior vena cava collapsibility measured by bedside ultrasonography among adults receiving maintenance haemodialysis: a prospective method-comparison study.
  29. Clinical predictors of falls and orthostatic hypotension among adults aged sixty-five years or older receiving cardiovascular medicines: a cross-sectional analytical study using the Clinical Frailty Scale and medication burden.
  30. Audit of cardiovascular medication burden, orthostatic blood pressure assessment and fall-risk documentation among hospitalised adults aged sixty-five years or older: a retrospective record-based study against geriatric care standards.

Looking for premium Cardiology thesis topics for your DM? Or the full medicine collection across all sections? Updated September 2026.

📌 Updated for 2026–2027 MD and DNB Medicine admissions: Cardiology

The accompanying guidance has been reviewed for diagnostic definitions, measurement timing, treatment-related changes and realistic follow-up within a medicine residency.

  • Many projects can use clinical assessment, standardised blood-pressure measurement, ECG, routine biochemistry and available echocardiography; confirm assay access and cardiology support before registration.
  • Cardiac MRI, coronary CT, invasive angiography, strain imaging and prolonged rhythm monitoring are not prerequisites for every study; select these only when clinically appropriate access and funding are confirmed.
  • Publication potential is stronger when the question addresses a local diagnostic, prognostic or care-delivery gap with consistent definitions, adequate follow-up and clinically interpretable results.
Generate a protocol from any topic above

Select Generate Protocol → beside any title in the list above and receive a submission-ready document built around that topic, containing all eighteen components:

  • Introduction / Synopsis
  • Research Question
  • Aim of the Study
  • Primary Objective
  • Secondary Objectives
  • Materials and Methods
  • Inclusion Criteria
  • Exclusion Criteria
  • Sample Size Calculation
  • Methodology
  • Statistical Analysis
  • Ethical Considerations
  • Review of Literature
  • References
  • Gantt Chart / Study Timeline
  • Patient Information Sheet
  • Consent Form
  • Data Collection Form

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Alongside cardiology protocols and synopses, support is also available for departmental presentations, journal club presentations, ethics committee presentations, and posters and oral presentations for medical conferences — for postgraduate residents, board trainees and research scholars across India and the GCC. Prepared by a practising doctor with long experience in medical publishing and thesis supervision.

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Cardiology research outside India

The topics above work as research questions anywhere — what changes is the document the institution expects, and who approves it before data collection begins. The Gulf equivalent of an Indian synopsis is the cardiology research proposal submitted to an institutional review board, and it ordinarily carries three sections an Indian synopsis does not: a Gantt chart, a budget and resources section, and a Declaration of Helsinki statement.

Board and residency programmes — country by country

Saudi Arabia — SCFHS and the Saudi Board. Residency and fellowship training under the Saudi Commission for Health Specialties includes a research project with a set timeline, and the cardiology research proposal is the document prepared at the outset and cleared by the institutional review board before recruitment starts.

United Arab Emirates — DHA, DOH Abu Dhabi and MOHAP. Residents training in Dubai, Abu Dhabi and the northern emirates prepare a cardiology research protocol for their programme and submit it for institutional review board approval before any data are collected.

Qatar — DHP (formerly QCHP) and Hamad Medical Corporation. A cardiology IRB proposal is reviewed before recruitment, with the ethics section written to the institution's own template rather than a generic one.

Bahrain — NHRA. Trainees turning cardiology research topics into a project need the proposal cleared by their institutional research and ethics committee before fieldwork begins.

Oman — OMSB. Residency programmes under the Oman Medical Specialty Board include a research component, and the cardiology research proposal is the document assessed at the start of it.

Kuwait — KIMS. A cardiology study protocol goes to the institutional committee for approval before the project begins.

Arab Board programmes across the region. The Arab Board carries its own research requirement irrespective of the host country, and the cardiology proposal follows the same structure throughout.

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Postgraduate degrees — Malaysia, the Gulf and beyond

Malaysia — MMed, the National Medical Research Register and MREC. A cardiology dissertation proposal for a Master of Medicine programme carried out in a Ministry of Health facility must be registered on the NMRR and approved by the Medical Research and Ethics Committee before the study begins, and the guidance asks for submission four to six months ahead of data collection. Every investigator on the study team registers on the NMRR as well, so the methodology, ethics and team sections are written in far more detail than an Indian synopsis requires.

PhD and Master's candidates elsewhere. University programmes generally require a full cardiology research proposal of roughly 6,000 to 10,000 words, with an extended literature review, a theoretical framework and a detailed methodology chapter.

PhD and MMed proposals are written individually by a medical doctor and revised until the supervisor accepts them. They are not produced by the automated protocol generator.

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🔥 Trending research areas in Cardiology for 2026–27

  • Heart failure phenotyping and cardiometabolic risk: evaluating obesity, diabetes and kidney dysfunction alongside clinical and echocardiographic findings, rather than classifying the syndrome from ejection fraction alone.
  • Implementation of evidence-based heart failure care: examining eligibility, prescribing, access, tolerability and follow-up, with reasons for non-prescription distinguished from missed treatment opportunities.
  • Integrated assessment of congestion: comparing clinical findings, available natriuretic peptides and lung ultrasound at defined treatment stages to study complementary information and reproducibility.
  • Digital cardiovascular assessment: evaluating available ECG interpretation or rhythm-monitoring tools with independent clinician confirmation, patient-level analysis and explicit handling of artefact and inconclusive recordings.

Protocol and synopsis guidance

What a Cardiology protocol must contain

Define the syndrome and classification. Specify criteria for coronary events, heart failure, hypertension, arrhythmias or valve disease, as applicable. Name the guideline or consensus edition adopted and document how updates during the study will be handled. Use the relevant ESC guideline collection to identify applicable contemporary guidance. Do not silently pool diagnoses classified under different definitions.

Fix the measurement window. Record symptom onset, hospital arrival, blood sampling, ECG, echocardiography and major treatment times. Specify whether the principal measurements represent presentation, early treatment or a stable discharge state. Troponin kinetics, fluid status, blood pressure and ventricular loading can change during admission. Research sampling must not delay reperfusion, treatment of unstable arrhythmia or other urgent care.

Standardise measurements and interpretation. State the troponin assay and its applicable reference limits, ECG criteria, blood-pressure technique and echocardiographic acquisition and measurement methods. Record rhythm, image quality and relevant haemodynamic conditions. Plan reader blinding and reproducibility assessment where interpretation is subjective; two readers agreeing does not establish diagnostic accuracy.

Make the outcome independent of the predictor. Avoid evaluating a biomarker against a disease definition that already requires that biomarker without acknowledging incorporation bias. Define admission, discharge and follow-up endpoints separately. If angiography is the reference, explain how participants who do not undergo it will be handled instead of analysing only a selectively investigated subgroup as though it represented all patients.

Cardiology synopsis versus Cardiology protocol

The synopsis summarises the rationale, objectives, population, design, sample-size basis and essential methods for institutional submission. The protocol provides the detail needed to conduct the study consistently, although institutional terminology may overlap.

For cardiology, the synopsis must already state the clinical state and timing of the primary measurements. The full protocol specifies how to handle tests performed after diuresis or revascularisation, changing rhythm, repeated admissions and missing follow-up. Both documents should distinguish association, diagnostic accuracy and prognosis. A cross-sectional correlation between a biomarker and ejection fraction does not show that the biomarker predicts future cardiovascular events.

Sample size and statistical analysis

Calculate for one primary endpoint. Use a justified expected proportion and precision for prevalence, an anticipated difference and variability for group comparisons, or an expected correlation for a correlation study. Prognostic models require enough outcome events relative to the planned model complexity; a large total sample with few events may still be inadequate. Include realistic allowances for missing measurements and loss to follow-up.

Account for treatment and repeated observations. Record clinically relevant confounders such as age, sex, renal function, diabetes, haemoglobin, rhythm and baseline disease severity. Treatment choice often reflects severity, contraindications and affordability, so an observational drug comparison cannot assume comparable groups. Serial ECGs, echocardiograms or admissions from one patient are not independent participants.

Match analysis to follow-up. Use paired or repeated-measures methods for serial assessments and appropriate time-to-event methods when follow-up varies. Prespecify the components of any composite cardiovascular endpoint and report them separately. State whether hospitalisation means first or recurrent admission and how death will be handled. Report effect sizes and confidence intervals; select a local diagnostic threshold only with an explicit plan for evaluating its optimism and generalisability.

Frequently Asked Questions – Cardiology Thesis Topics (2026–27)

1. How do I choose a feasible Cardiology thesis topic for MD or DNB Medicine?

For 2026–2027 admissions, choose a common clinical problem with sufficient eligible patients and tests already available in the institution. Check echocardiography access, assay costs, cardiology collaboration and the ability to complete follow-up. Prefer one clear primary outcome to multiple biomarkers or uncommon interventions whose recruitment is uncertain.

2. Which study designs are suitable for a Cardiology thesis?

Cross-sectional studies suit contemporaneous associations, cohorts suit subsequent outcomes, diagnostic-accuracy studies require a suitable reference assessment, and case-control studies can examine selected associations. Retrospective designs need adequate records. Treatment allocation by routine clinical choice remains observational; a research-assigned intervention needs the corresponding trial design and approvals. Confirm institutional acceptance of the proposed design.

3. What should I settle with my guide before finalising the title?

Agree on the population, diagnostic criteria, primary endpoint, measurement window, sample-size basis and follow-up duration. Confirm assay and imaging access, reader responsibilities and collaboration with the treating unit. Specify whether measurements are taken before or after major treatment and how repeated admissions, renal dysfunction, atrial fibrillation and missing data will be handled.

4. Can I complete a Cardiology thesis without angiography or advanced cardiac imaging?

Yes. Many questions involving hypertension, ECG findings, standard echocardiography, clinical risk factors and routine laboratory measurements are feasible without advanced imaging. Choose a question that those measurements can actually answer. A study claiming angiographic coronary severity needs suitable angiography data, whereas a clinical association study should not imply that obstructive coronary disease has been anatomically confirmed.

5. Is a Cardiology synopsis different from a Cardiology protocol?

The synopsis usually presents the proposed study for review and registration, while the protocol describes its detailed conduct. Local terminology varies. Both must agree on case definitions, timing of measurements, endpoints, sample size, analysis and ethics. The protocol additionally documents operational details such as serial testing, outcome adjudication and follow-up procedures.

6. What ethical safeguards are needed for a Cardiology thesis?

Obtain Institutional Ethics Committee review and applicable consent; retrospective records or PACS review require an approved waiver where justified. Adult-only studies need no child-assent procedure; if children are included, obtain guardian permission and age-appropriate assent from about seven years. A routine-care observational design should add no research-only radiation, contrast or venepuncture and specify 0 mL extra research blood. Justify any additional blood volume, sampling frequency, scan, sequence or contrast exposure and obtain approval. Seek separate consent for identifiable photographs or video.

Remove identifiers from records, DICOM headers and any reconstructed facial surfaces. Define immediate escalation to the reporting cardiologist or treating team for suspected acute ischaemia, dangerous arrhythmia, severe valve disease or other urgent incidental findings. Research procedures must not delay treatment.

Use ICMR ethical guidance when preparing these safeguards.

7. Can an elevated troponin alone define myocardial infarction in my study?

No. An elevated cardiac troponin indicates myocardial injury; myocardial infarction requires the appropriate evidence of acute myocardial ischaemia under the adopted consensus definition. Record the assay, applicable reference limit, serial sampling and relevant symptoms, ECG or imaging evidence. Renal dysfunction, heart failure and other illnesses can complicate interpretation. Prespecify adjudication rather than classifying every troponin-positive admission as infarction, and distinguish acute from chronic injury using the clinical course and serial results.

8. Can these topics support a PhD proposal or a Gulf board research project?

Yes, with adaptation. A PhD proposal requires a substantive original contribution beyond the usual MD synopsis. For SCFHS and Saudi Board programmes, the Arab Board of Health Specializations, and DHP-, DHA-, DOH- or MOHAP-linked training programmes, confirm the applicable curriculum, supervision and local ethics requirements. Where a board research project is mandatory, align its scope and assessment milestones with that programme. Do not assume uniform research obligations or dissertation formats across these bodies and linked programmes.

9. When should I register my Cardiology thesis topic?

Follow the university or training board deadline after guide agreement and a feasibility review. Obtain the required scientific, departmental and ethics approvals before recruitment, research testing or research access to identifiable records. Work backwards from submission to allow time for recruitment, the full planned follow-up period, analysis and writing; the last recruited participant also needs that follow-up window.

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